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    ALDH2 aldehyde dehydrogenase 2 family member [ Homo sapiens (human) ]

    Gene ID: 217, updated on 8-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Activation of mitochondrial aldehyde dehydrogenase 2 promotes hair growth in human hair follicles.

    Activation of mitochondrial aldehyde dehydrogenase 2 promotes hair growth in human hair follicles.
    Lee S, Ohn J, Kang BM, Hwang ST, Kwon O., Free PMC Article

    10/7/2024
    Associations of ADH1B and ALDH2 genotypes and alcohol flushing with drinking history, withdrawal symptoms, and ICD-10 criteria in Japanese alcohol-dependent men.

    Associations of ADH1B and ALDH2 genotypes and alcohol flushing with drinking history, withdrawal symptoms, and ICD-10 criteria in Japanese alcohol-dependent men.
    Yokoyama A, Yokoyama T, Yumoto Y, Takimura T, Toyama T, Yoneda J, Nishimura K, Minobe R, Matsuzaki T, Kimura M, Matsushita S.

    09/17/2024
    Multi-Omics profiling identifies aldehyde dehydrogenase 2 as a critical mediator in the crosstalk between Treg-mediated immunosuppression microenvironment and hepatocellular carcinoma.

    Multi-Omics profiling identifies aldehyde dehydrogenase 2 as a critical mediator in the crosstalk between Treg-mediated immunosuppression microenvironment and hepatocellular carcinoma.
    Liu ZY, Lin XH, Guo HY, Shi X, Zhang DY, Sun JL, Zhang GC, Xu RC, Wang F, Yu XN, Wang D, Weng SQ, Shen XZ, Liu TT, Dong L, Zhu JM., Free PMC Article

    08/22/2024
    Exploring patterns of alcohol use and alcohol use disorder among Asian Americans with a finer lens.

    Exploring patterns of alcohol use and alcohol use disorder among Asian Americans with a finer lens.
    Zhang H, Ruan WJ, Chou SP, Saha TD, Fan AZ, Huang B, White AM.

    06/20/2024
    Research Progress on the Correlation between Acetaldehyde Dehydrogenase 2 and Hepatocellular Carcinoma Development.

    Research Progress on the Correlation between Acetaldehyde Dehydrogenase 2 and Hepatocellular Carcinoma Development.
    Yang D, Hu Y, Yang J, Tao L, Su Y, Wu Y, Yao Y, Wang S, Ye S, Xu T.

    04/25/2024
    To determine the frequency of aldehyde dehydrogenase type 2 (aldh2) deficiency in aplastic anaemia: A single center experience from pakistan.

    To determine the frequency of aldehyde dehydrogenase type 2 (aldh2) deficiency in aplastic anaemia: A single center experience from pakistan.
    Shamim N, Khan MA, Iftikhar R, Akram Z, Jamshaid H, Rehman J, Chaudhry QUN, Ghafoor T.

    04/17/2024
    The ALDH2 gene rs671 polymorphism is associated with cardiometabolic risk factors in East Asian population: an updated meta-analysis.

    The ALDH2 gene rs671 polymorphism is associated with cardiometabolic risk factors in East Asian population: an updated meta-analysis.
    Liu R, Peng M, Zhang J, Qiu K, Zeng T, Chen L., Free PMC Article

    04/4/2024
    The aldehyde dehydrogenase 2 rs671 variant enhances amyloid beta pathology.

    The aldehyde dehydrogenase 2 rs671 variant enhances amyloid β pathology.
    Wang X, Wang J, Chen Y, Qian X, Luo S, Wang X, Ma C, Ge W., Free PMC Article

    03/28/2024
    Aldehyde Dehydrogenase 2 (ALDH2) rs671 Polymorphism is a Predictor of Pulmonary Hypertension Due to Left Heart Disease.

    Aldehyde Dehydrogenase 2 (ALDH2) rs671 Polymorphism is a Predictor of Pulmonary Hypertension Due to Left Heart Disease.
    Tang C, Shi F, Ji Y, Zhu J, Gu X.

    03/13/2024
    Changes of neurofilament light chain in patients with alcohol dependence following withdrawal and the genetic effect from ALDH2 Polymorphism.

    Changes of neurofilament light chain in patients with alcohol dependence following withdrawal and the genetic effect from ALDH2 Polymorphism.
    Huang MC, Tu HY, Chung RH, Kuo HW, Liu TH, Chen CH, Mochly-Rosen D, Liu YL., Free PMC Article

    03/12/2024
    ALDH2: Essential Mediator for the Remote Ischemic Conditioning Strategy to Reduce Myocardial Ischemia/Reperfusion Injury.

    ALDH2: Essential Mediator for the Remote Ischemic Conditioning Strategy to Reduce Myocardial Ischemia/Reperfusion Injury.
    Zhu Y, Jiao Z, Bei Y.

    02/28/2024
    ALDH2 is a novel biomarker and exerts an inhibitory effect on melanoma.

    ALDH2 is a novel biomarker and exerts an inhibitory effect on melanoma.
    Lei H, Liao J, Wang X, Huang R, Ying C, Yang J., Free PMC Article

    02/23/2024
    ALDH2 deficiency exacerbates MCD-diet induced MASLD by modulating bile acid metabolism.

    ALDH2 deficiency exacerbates MCD-diet induced MASLD by modulating bile acid metabolism.
    Luo J, Lu Z, Zhong Z, Pi M, Xiong Y, Li L, Chen T, Chen Y, Wang CY, Liu Z, Ye Q.

    01/29/2024
    Relationship between esophageal squamous cell carcinoma risk and alcohol-related ALDH2 and ADH1B polymorphisms: Evidence from a meta-analysis and Mendelian randomization analysis.

    Relationship between esophageal squamous cell carcinoma risk and alcohol-related ALDH2 and ADH1B polymorphisms: Evidence from a meta-analysis and Mendelian randomization analysis.
    Zhang B, Peng YH, Luo Y, Hong CQ, Lin YW, Zhang YL, Xu YW, Su XF, Wu FC., Free PMC Article

    12/6/2023
    ALDH2 polymorphism rs671 and alcohol consumption: possible explanatory factors for race/ethnic differences in bone density.

    ALDH2 polymorphism rs671 and alcohol consumption: possible explanatory factors for race/ethnic differences in bone density.
    Tokiya M, Kobayashi T, Kido MA, Matsumoto A.

    11/18/2023
    A Single nucleotide polymorphism in the ALDH2 gene modifies the risk of esophageal squamous cell carcinoma in BRCA2 p.K3326* carriers.

    A Single nucleotide polymorphism in the ALDH2 gene modifies the risk of esophageal squamous cell carcinoma in BRCA2 p.K3326* carriers.
    Zamani N, Szymiczek A, Shakeri R, Poustchi H, Pourshams A, Narod S, Malekzadeh R, Akbari MR., Free PMC Article

    11/14/2023
    The effect of vitamin C on nitroglycerin-mediated vasodilation in individuals with and without the aldehyde dehydrogenase 2 polymorphism.

    The effect of vitamin C on nitroglycerin-mediated vasodilation in individuals with and without the aldehyde dehydrogenase 2 polymorphism.
    He JD, Parker JD.

    11/7/2023
    Genetic influences on alcohol flushing in East Asian populations.

    Genetic influences on alcohol flushing in East Asian populations.
    Cho Y, Lin K, Lee SH, Yu C, Valle DS, Avery D, Lv J, Jung K, Li L, Smith GD, China Kadoorie Biobank Collaborative Group, Sun D, Chen Z, Millwood IY, Hemani G, Walters RG., Free PMC Article

    11/1/2023
    Aldehyde dehydrogenase 2 gene rs671 G>A polymorphism is associated with an increased risk of digestive tract cancer.

    Aldehyde dehydrogenase 2 gene rs671 G>A polymorphism is associated with an increased risk of digestive tract cancer.
    Yang Y, Liang Q, Chen Y, Cao Y, Zhuo Q, Liu B, Wang S., Free PMC Article

    10/28/2023
    Prognostic Significance of a Model Based on Acetaldehyde Dehydrogenase 2 Genetic Polymorphisms in Laryngeal Carcinoma.

    Prognostic Significance of a Model Based on Acetaldehyde Dehydrogenase 2 Genetic Polymorphisms in Laryngeal Carcinoma.
    Ye Y, Wu T, Liang F, Fan J, Song P, Li Y, Xie W, Huang X, Han P.

    09/1/2023
    A Common East Asian aldehyde dehydrogenase 2*2 variant promotes ventricular arrhythmia with chronic light-to-moderate alcohol use in mice.

    A Common East Asian aldehyde dehydrogenase 2*2 variant promotes ventricular arrhythmia with chronic light-to-moderate alcohol use in mice.
    Lee AS, Sung YL, Pan SH, Sung KT, Su CH, Ding SL, Lu YJ, Hsieh CL, Chen YF, Liu CC, Chen WY, Chen XR, Chung FP, Wang SW, Chen CH, Mochly-Rosen D, Hung CL, Yeh HI, Lin SF., Free PMC Article

    08/25/2023
    Efficacy of Low-Dose Aspirin in Colorectal Cancer Risk Prevention is Dependent on ADH1B and ALDH2 Genotype in Japanese Familial Adenomatous Polyposis Patients.

    Efficacy of Low-Dose Aspirin in Colorectal Cancer Risk Prevention is Dependent on ADH1B and ALDH2 Genotype in Japanese Familial Adenomatous Polyposis Patients.
    Mure K, Ishikawa H, Mutoh M, Horinaka M, Otani T, Suzuki S, Wakabayashi K, Sakai T, J-FAPP Study IV group., Free PMC Article

    08/9/2023
    Associations of alcohol intake with subclinical carotid atherosclerosis in 22,000 Chinese adults.

    Associations of alcohol intake with subclinical carotid atherosclerosis in 22,000 Chinese adults.
    Zhou T, Im PK, Hariri P, Du H, Guo Y, Lin K, Yang L, Yu C, Chen Y, Sohoni R, Avery D, Guan M, Yang M, Lv J, Clarke R, Li L, Walters RG, Chen Z, Millwood IY, China Kadoorie Biobank Group., Free PMC Article

    07/30/2023
    [Aldehyde dehydrogenase 2 rs671 genetic polymorphisms are associated with chemotherapy-induced nausea and vomiting].

    [Aldehyde dehydrogenase 2 rs671 genetic polymorphisms are associated with chemotherapy-induced nausea and vomiting].
    Yang Q, Liu X, Jiang Y, Ma J., Free PMC Article

    07/17/2023
    Effects of the genetic variants of alcohol-metabolizing enzymes on lipid levels in Asian populations: a systematic review and meta-analysis.

    Effects of the genetic variants of alcohol-metabolizing enzymes on lipid levels in Asian populations: a systematic review and meta-analysis.
    Luo Z, Cheng J, Wang Y.

    07/12/2023
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