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    F7 coagulation factor VII [ Homo sapiens (human) ]

    Gene ID: 2155, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    [Pedigree Analysis of Hereditary Coagulation Factor XII Deficiency Caused by Compound Heterozygous Mutation p.Gly175Cys and p.Gly542Ser of F12 Gene].

    [Pedigree Analysis of Hereditary Coagulation Factor XII Deficiency Caused by Compound Heterozygous Mutation p.Gly175Cys and p.Gly542Ser of F12 Gene].
    Cheng XL, Yang T, Yang L, Xin YJ, He M, Zhu L, Liu JY.

    07/17/2024
    [Congenital F Deficiency Associated with a Novel Mutation in F7 Gene].

    [Congenital FⅦ Deficiency Associated with a Novel Mutation in F7 Gene].
    Wang YY, Zhang YG, Chen WB.

    07/16/2024
    Frequency of the p.Thr241Asn mutation in Chinese patients with congenital factor VII deficiency.

    Frequency of the p.Thr241Asn mutation in Chinese patients with congenital factor VII deficiency.
    Zhou P, Peng Y, Li Q, Huang Q, Kong Y.

    03/5/2024
    Acquired factor VII deficiency in pediatric inflammatory bowel disease: Report of three cases.

    Acquired factor VII deficiency in pediatric inflammatory bowel disease: Report of three cases.
    Çakar S, Eren G, Karapınar TH, Ecevıt ÇÖ, Bekem Ö.

    12/22/2023
    Structural and functional characterization of novel F7 mutations identified in Chinese factor VII-deficient patients.

    Structural and functional characterization of novel F7 mutations identified in Chinese factor VII-deficient patients.
    Lou C, Jiang J, Chen W, Zhang Z, Xu G, Liu Y, Dai J, Ding Q, Wang X, Wei H, Wu Y, Xu Q, Wu W.

    08/2/2023
    Factor VII deficiency: A cause of (or risk factor for) bleeding?

    Factor VII deficiency: A cause of (or risk factor for) bleeding?
    Hampshire DJ.

    07/26/2023
    Factor VII Padua in Iran: clinical and laboratory findings of three unrelated patients.

    Factor VII Padua in Iran: clinical and laboratory findings of three unrelated patients.
    Shams M, Hassani S, Dorgalaleh A, Zamani F, Ahmadi A.

    04/14/2023
    Phenotypic variation in severe hemophilia A is related to endogenous thrombin potential and plasma levels of factor VII.

    Phenotypic variation in severe hemophilia A is related to endogenous thrombin potential and plasma levels of factor VII.
    Chaves DG, Fonseca FML, Araújo HCB, de Oliveira LMM, Amorim MVA, Assis Neto CC, Carvalho MDG.

    12/3/2022
    Clinical phenotype and F7 gene genotype in 40 Tunisian patients with congenital factor VII deficiency.

    Clinical phenotype and F7 gene genotype in 40 Tunisian patients with congenital factor VII deficiency.
    Ouardani C, Elmahmoudi H, ELborgi W, Gharbi M, Meriem A, Gouider E.

    07/16/2022
    Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding.

    Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding.
    Andersen E, Chollet ME, Sletten M, Stavik B, Skarpen E, Backe PH, Thiede B, Glosli H, Henriksson CE, Iversen N.

    03/19/2022
    FVII gene R353Q polymorphism and coronary heart disease: a meta-analysis including 3258 subjects.

    FVII gene R353Q polymorphism and coronary heart disease: a meta-analysis including 3258 subjects.
    Li YY, Wang H, Zhang YY.

    03/19/2022
    Factor VIIa suppresses inflammation and barrier disruption through the release of EEVs and transfer of microRNA 10a.

    Factor VIIa suppresses inflammation and barrier disruption through the release of EEVs and transfer of microRNA 10a.
    Das K, Keshava S, Pendurthi UR, Rao LVM., Free PMC Article

    02/26/2022
    Contribution of factor VII polymorphisms to coagulopathy in patients with isolated traumatic brain injury.

    Contribution of factor VII polymorphisms to coagulopathy in patients with isolated traumatic brain injury.
    Fang J, Yuan Q, Du Z, Liu C, Xu H, Yang W, Chen L, Zhao J, Xie R, Hu J, Wu X.

    01/29/2022
    Novel factor VII gene mutations in six families with hereditary coagulation factor VII deficiency.

    Novel factor VII gene mutations in six families with hereditary coagulation factor VII deficiency.
    Zhang X, Wang S, Leng S, Feng Q, Zhang Y, Xu S, Zhang L, Zhang X, Fang Y, Peng J, Sheng Z., Free PMC Article

    01/22/2022
    Compound Heterozygous Mutations in the F7 Gene in 2 Unrelated Families With Congenital Factor VII Deficiency.

    Compound Heterozygous Mutations in the F7 Gene in 2 Unrelated Families With Congenital Factor VII Deficiency.
    Ma C, Wang Y, Gao H, Xue L, Wu S, Xu X, Zhang H, Li C.

    01/8/2022
    Determining the association of thrombophilic gene polymorphisms with recurrent pregnancy loss in Iranian women.

    Determining the association of thrombophilic gene polymorphisms with recurrent pregnancy loss in Iranian women.
    Khorshidi F, Hajizadeh S, Choobineh H, Alizadeh S, Sharifi MJ, Kavosh Z, Omidkhoda A.

    10/2/2021
    Factor VII Activating Protease Expression in Human Platelets and Accumulation in Symptomatic Carotid Plaque.

    Factor VII Activating Protease Expression in Human Platelets and Accumulation in Symptomatic Carotid Plaque.
    Parahuleva MS, Worsch M, Euler G, Choukeir M, Mardini A, Parviz B, Kanse SM, Portig I, Khayrutdinov E, Schieffer B, Markus B., Free PMC Article

    03/13/2021
    Efficient refolding and reconstitution of tissue factor into nanodiscs facilitates structural investigation of a multicomponent system on a lipid bilayer.

    Efficient refolding and reconstitution of tissue factor into nanodiscs facilitates structural investigation of a multicomponent system on a lipid bilayer.
    Tidemand FG, Østergaard H, Ploug M, Kragelund BB, Arleth L.

    08/22/2020
    Association Between R353Q (rs6046) Polymorphism in Factor VII with Coronary Heart Disease.

    Association Between R353Q (rs6046) Polymorphism in Factor VII with Coronary Heart Disease.
    Li F, Hu S, Zhou X, Mei X, Zhou Y.

    08/15/2020
    Thrombotic Events in Homozygotes with a Proven or Highly Probable Arg304Gln Factor VII Mutation (FVII Padua)1): Only Limited Replacement Therapy is Needed in Case of Surgery.

    Thrombotic Events in Homozygotes with a Proven or Highly Probable Arg304Gln Factor VII Mutation (FVII Padua)1): Only Limited Replacement Therapy is Needed in Case of Surgery.
    Girolami A, Cosi E, Ferrari S, Girolami B, Randi ML.

    08/13/2020
    Compound coagulation factor VII (FVII) heterozygous mutations (p.Lys341Glu and nt27 del CT) which were responsible for the bleeding tendency were found in a pedigree of inherited FVII deficiency.

    Analysis of Phenotype and Genotypein an Inherited Coagulation Factor VII Deficiency Pedigree.
    Li M, Jin Y, Wang M, Ding H.

    05/23/2020
    High Factor VII expression is associated with ischemic stroke.

    A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.
    de Vries PS, Sabater-Lleal M, Huffman JE, Marten J, Song C, Pankratz N, Bartz TM, de Haan HG, Delgado GE, Eicher JD, Martinez-Perez A, Ward-Caviness CK, Brody JA, Chen MH, de Maat MPM, Frånberg M, Gill D, Kleber ME, Rivadeneira F, Soria JM, Tang W, Tofler GH, Uitterlinden AG, van Hylckama Vlieg A, Seshadri S, Boerwinkle E, Davies NM, Giese AK, Ikram MK, Kittner SJ, McKnight B, Psaty BM, Reiner AP, Sargurupremraj M, Taylor KD, INVENT Consortium, MEGASTROKE Consortium of the International Stroke Genetics Consortium, Fornage M, Hamsten A, März W, Rosendaal FR, Souto JC, Dehghan A, Johnson AD, Morrison AC, O'Donnell CJ, Smith NL., Free PMC Article

    11/16/2019
    The Lys341Glu and IVS6-1G>A mutations probably underlie the reduced activity of FVII in this pedigree with hereditary coagulation factor VII deficiency.

    [Genetic analysis and clinical features of a pedigree affected with hereditary coagulation factor Ⅶ deficiency caused by compound heterozygotic mutations].
    Jin Y, Yang L, Zhang F, Liu M, Su K, Li X, Wang M.

    11/2/2019
    Two novel heterozygous missense variants of the F7 gene [c.1371G>T(p.Arg439Ser) and c.278G>T(p.Arg75Met)] probably account for the decrease of factor VII in the two pedigrees

    [Clinical and genotypic analysis of two Chinese pedigrees affected with hereditary coagulable factor VII deficiency].
    Li F, Liu J, Zhu Q, Shen C, Shu K, Yang X, Yang W, Lin S, Chen B, Jiang M.

    08/31/2019
    F7 and PROCR SNPs are important determinants of variation in circulating FVIIa and FVIIa-AT levels. Findings suggest that higher FVIIa is a risk factor for ischemic stroke in older adults, whereas FVIIa-AT may reflect mortality risk.

    Associations of activated coagulation factor VII and factor VIIa-antithrombin levels with genome-wide polymorphisms and cardiovascular disease risk.
    Olson NC, Raffield LM, Lange LA, Lange EM, Longstreth WT Jr, Chauhan G, Debette S, Seshadri S, Reiner AP, Tracy RP., Free PMC Article

    07/13/2019
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