Protease-activated receptor 2 drives migration in a colon cancer cell line but not in noncancerous human epithelial cells.
Périco LL, Vegso AJ, Baggio CH, MacNaughton WK.

A novel trypsin of Trichinella spiralis mediates larval invasion of gut epithelium via binding to PAR2 and activating ERK1/2 pathway.
Han LL, Lu QQ, Zheng WW, Li YL, Song YY, Zhang XZ, Long SR, Liu RD, Wang ZQ, Cui J., Free PMC Article

Single-Nucleotide Polymorphisms of the PAR2 and IL-17A Genes Are Significantly Associated with Chronic Pain.
Soeda M, Ohka S, Nishizawa D, Iseki M, Yamaguchi K, Arita H, Hanaoka K, Kato J, Ogawa S, Hiranuma A, Hasegawa J, Nakayama K, Ebata Y, Hayashida M, Ichinohe T, Fukuda KI, Ikeda K., Free PMC Article

Bcl-xL mediates interferon-beta secretion by protease-activated receptor 2 deficiency through the mitochondrial permeability transition pore in colorectal cancer metastasis.
Ma J, Liu Y, Yuan J, Ma Y, Zhao X, Chen K, Zhang X, Zhang F, Wang H.

Comparison of pancreatic enzyme abnormalities and protease-activated receptor-2-positive eosinophils in the duodenum of patients with functional dyspepsia-irritable bowel syndrome overlap with functional dyspepsia alone in Asian populations.
Futagami S, Kessoku T, Kasai Y, Higurashi T, Nakajima A, Agawa S, Yamawaki H, Nakamura K, Habiro M, Kawawa R, Ueki N, Higashida S, Watanabe Y, Yamato H, Yamamoto T, Takasaki Y, Ito K, Hojo M, Isayama H, Motoda N, Ohashi R, Siah KTH, Ng CK, Gwee KA.

PAR2 deficiency tunes inflammatory microenvironment to magnify STING signalling for mitigating cancer metastasis via anionic CRISPR/Cas9 nanoparticles.
Fu X, Li J, Wu Y, Mao C, Jiang Y.

Shear Stress Drives the Cleavage Activation of Protease-Activated Receptor 2 by PRSS3/Mesotrypsin to Promote Invasion and Metastasis of Circulating Lung Cancer Cells.
Zhou M, Li K, Luo KQ., Free PMC Article

Protease secretions by the invading blastocyst induce calcium oscillations in endometrial epithelial cells via the protease-activated receptor 2.
Hennes A, Devroe J, De Clercq K, Ciprietti M, Held K, Luyten K, Van Ranst N, Maenhoudt N, Peeraer K, Vankelecom H, Voets T, Vriens J., Free PMC Article

[The expression and significance of protease activated receptor 2 in ovarian epithelial carcinoma].
Liu SH, Ma YM, Zhang YN, Zhao XH, Wang HY, Li B.

Protease-activated receptor type 2 activation downregulates osteogenesis in periodontal ligament stem cells.
França BN, Gasparoni LM, Rovai ES, Ambrósio LMB, Mendonça NF, Hagy MH, Mendoza AH, Sipert CR, Holzhausen M.

Human Induced Pluripotent Stem Cell-Derived Keratinocyte-Like Cells for Research on Protease-Activated Receptor 2 in Nonhistaminergic Cascades of Atopic Dermatitis .
Nishimoto R, Kodama C, Yamashita H, Hattori F.

PAR2: The Cornerstone of Pancreatic Diseases.
Suhaj P, Olejar T, Matej R., Free PMC Article

GPR97 triggers inflammatory processes in human neutrophils via a macromolecular complex upstream of PAR2 activation.
Chu TY, Zheng-Gérard C, Huang KY, Chang YC, Chen YW, I KY, Lo YL, Chiang NY, Chen HY, Stacey M, Gordon S, Tseng WY, Sun CY, Wu YM, Pan YS, Huang CH, Lin CY, Chen TC, El Omari K, Antonelou M, Henderson SR, Salama A, Seiradake E, Lin HH., Free PMC Article

Trypsin may be associated with duodenal eosinophils through the expression of PAR2 in early chronic pancreatitis and functional dyspepsia with pancreatic enzyme abnormalities.
Agawa S, Futagami S, Yamawaki H, Tsushima R, Higuchi K, Habiro M, Kawawa R, Kodaka Y, Ueki N, Watanabe Y, Gudis K, Ohashi R, Iwakiri K., Free PMC Article

Candida albicans Sap6 Initiates Oral Mucosal Inflammation via the Protease Activated Receptor PAR2.
Kumar R, Rojas IG, Edgerton M., Free PMC Article

Expression of Proteinase-activated Receptor 2 (PAR2) as a Correlate of Concern in Triple-negative Breast Cancer (TNBC).
Kapatia G, Kaur S, Kumar S, Laroiya I, Singh G, Sharma M, Bal A, Luthra-Guptasarma M.

Modulation of Intestinal Epithelial Permeability via Protease-Activated Receptor-2-Induced Autophagy.
Kim Y, Lee Y, Heo G, Jeong S, Park S, Yoo JW, Jung Y, Im E., Free PMC Article

Giardia duodenalis cysteine proteases cleave proteinase-activated receptor-2 to regulate intestinal goblet cell mucin gene expression.
Fekete E, Allain T, Amat CB, Mihara K, Saifeddine M, Hollenberg MD, Chadee K, Buret AG.

The activation fragment of PAR2 is elevated in serum from patients with rheumatoid arthritis and reduced in response to anti-IL6R treatment.
Kalogera S, He Y, Bay-Jensen AC, Gantzel T, Sun S, Manon-Jensen T, Karsdal MA, Thudium CS., Free PMC Article

Alternaria alternata-induced airway epithelial signaling and inflammatory responses via protease-activated receptor-2 expression.
Rivas CM, Schiff HV, Moutal A, Khanna R, Kiela PR, Dussor G, Price TJ, Vagner J, DeFea KA, Boitano S., Free PMC Article

Mast Cells and Proteins Related to Myofibroblast Differentiation (PAR-2, IL-6, and TGFβ1) in Salivary Cancers: A Preliminary Study.
Ismerim AB, de Oliveira Araújo IB, de Aquino Xavier FC, Rocha CAG, Macedo CL, Cangussu MCT, Freitas VS, Della Coletta R, Cury PR, Santos JN.

Protease-activated receptor 2 stabilizes Bcl-xL and regulates EGFR-targeted therapy response in colorectal cancer.
Li W, Ma Y, He L, Li H, Chu Y, Jiang Z, Zhao X, Nie Y, Wang X, Wang H.

Mast cell tryptase enhances wound healing by promoting migration in human bronchial epithelial cells.
Mogren S, Berlin F, Ramu S, Sverrild A, Porsbjerg C, Uller L, Andersson CK., Free PMC Article

Disruption of the biological activity of protease-activated receptors2/4 in adults rather than children in SARS CoV-2 virus-mediated mortality in COVID-19 infection.
Singh Y, Fuloria NK, Fuloria S, Subramaniyan V, Almalki WH, Gupta G, Shaikh MAJ, Singh M, Al-Abbasi FA, Kazmi I., Free PMC Article

Mast cell tryptase-PAR2 pathway in proliferation of prostatic stromal cells reacted with Trichomonas vaginalis.
Noh CS, Chung HY, Han IH, Kim JH, Kim YM, Ryu JS.