| TFCP2, a binding protein of ATF3, promotes the progression of glioma by activating the synthesis of serine. | TFCP2, a binding protein of ATF3, promotes the progression of glioma by activating the synthesis of serine.
Luo X, Ge J, Liu J, Liu Z, Bi C, Lan S. | 05/7/2022 |
| Mbd2-CP2c functional loop drives adult-type globin gene expression and erythroid differentiation of erythroid cells. | Mbd2-CP2c loop drives adult-type globin gene expression and definitive erythropoiesis.
Kim MY, Kim JS, Son SH, Lim CS, Eum HY, Ha DH, Park MA, Baek EJ, Ryu BY, Kang HC, Uversky VN, Kim CG., Free PMC Article | 08/10/2019 |
| The transcription factor CP2 upregulated miR-144 expression, which partially contributed to the suppression of COX-2 in mGCs. | MicroRNA-144 is regulated by CP2 and decreases COX-2 expression and PGE2 production in mouse ovarian granulosa cells.
Zhou J, Lei B, Li H, Zhu L, Wang L, Tao H, Mei S, Li F., Free PMC Article | 11/4/2017 |
| that yin yang 1 strongly localizes in the spermatogonial stem cells and co-localizes heterogeneously with CP2c to permit spermatogenesis | Reciprocal localization of transcription factors YY1 and CP2c in spermatogonial stem cells and their putative roles during spermatogenesis.
Kim JS, Chae JH, Cheon YP, Kim CG. | 03/4/2017 |
| Small molecule inhibitors of Late SV40 Factor abrogate hepatocellular carcinoma by inducing mitotic arrest and apoptosis. | Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model.
Rajasekaran D, Siddiq A, Willoughby JL, Biagi JM, Christadore LM, Yunes SA, Gredler R, Jariwala N, Robertson CL, Akiel MA, Shen XN, Subler MA, Windle JJ, Schaus SE, Fisher PB, Hansen U, Sarkar D., Free PMC Article | 07/30/2016 |
| Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma | Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma.
Grant TJ, Bishop JA, Christadore LM, Barot G, Chin HG, Woodson S, Kavouris J, Siddiq A, Gredler R, Shen XN, Sherman J, Meehan T, Fitzgerald K, Pradhan S, Briggs LA, Andrews WH, Sarkar D, Schaus SE, Hansen U., Free PMC Article | 05/12/2012 |
| present study shows that a transcription factor previously unrelated with epithelial-mesenchymal transition (EMT), TFCP2c/LSF/LBP-1c, was translocated to the nucleus and bound to the fibronectin promoter upon EMT induction by Snail1 | TFCP2c/LSF/LBP-1c is required for Snail1-induced fibronectin gene expression.
Porta-de-la-Riva M, Stanisavljevic J, Curto J, Francí C, Díaz VM, García de Herreros A, Baulida J. | 07/9/2011 |
| the binding of Pin1 at the Thr-329-Pro-330 motif in LSF permits isomerization by Pin1 of the peptide bonds at the nearby phosphorylated SP motifs (Ser-291 and Ser-309) to the trans configuration, thereby facilitating their dephosphorylation. | Prolyl isomerase Pin1 regulates transcription factor LSF (TFCP2) by facilitating dephosphorylation at two serine-proline motifs.
Saxena UH, Owens L, Graham JR, Cooper GM, Hansen U., Free PMC Article | 11/6/2010 |
| CP2 contributes to the pathogenesis of Alzheimer's disease by inducing transferrin expression via up-regulating its transcription. | Control of transferrin expression by β-amyloid through the CP2 transcription factor.
Jang SM, Kim JW, Kim CH, An JH, Kang EJ, Kim CG, Kim HJ, Choi KH. | 10/30/2010 |
| Results identify LSF as only the second known target (in addition to pRb) of cyclin C/CDK2 activity during progression from quiescence to early G(1). | Phosphorylation by cyclin C/cyclin-dependent kinase 2 following mitogenic stimulation of murine fibroblasts inhibits transcriptional activity of LSF during G1 progression.
Saxena UH, Powell CM, Fecko JK, Cacioppo R, Chou HS, Cooper GM, Hansen U., Free PMC Article | 01/21/2010 |
| These data suggest that CP2b potentiate erythroid cell-specific alpha-globin expression by recruiting CP2c into the nucleus. | The relative cellular levels of CP2a and CP2b potentiates erythroid cell-specific expression of the alpha-globin gene by regulating the nuclear localization of CP2c.
Chae JH, Kang HC, Kim CG. | 01/21/2010 |
| findings demonstrate that the APLP2-intracellular C-terminal domains interact with CP2 transcription factor in the nucleus and induce the expression of glycogen synthase kinase 3beta | Intracellular domains of amyloid precursor-like protein 2 interact with CP2 transcription factor in the nucleus and induce glycogen synthase kinase-3beta expression.
Xu Y, Kim HS, Joo Y, Choi Y, Chang KA, Park CH, Shin KY, Kim S, Cheon YH, Baik TK, Kim JH, Suh YH. | 01/21/2010 |
| CP2 plays important role during bone development by activating BMP4 transcription | Transcription factor CP2 is involved in activating mBMP4 in mouse mesenchymal stem cells.
Kang HC, Chae JH, Kim BS, Han SY, Kim SH, Auh CK, Yang SI, Kim CG. | 01/21/2010 |
| CP2 is a major factor in the regulation of globin expression in human and mouse erythroid cells, and CP2 binding to the globin gene promoter is essential for the enhanced transcription of globin genes in erythroid differentiation. | CP2 binding to the promoter is essential for the enhanced transcription of globin genes in erythroid cells.
Chae JH, Kim CG. | 01/21/2010 |
| A novel murine splice isoform of CP2, CP2b, which is identical to CP2a except that it has an additional 36 amino acids encoded by an extra exon was identified and characterized. | Erythroid cell-specific alpha-globin gene regulation by the CP2 transcription factor family.
Kang HC, Chae JH, Lee YH, Park MA, Shin JH, Kim SH, Ye SK, Cho YS, Fiering S, Kim CG., Free PMC Article | 01/21/2010 |