G-quadruplex folding in Xist RNA antagonizes PRC2 activity for stepwise regulation of X chromosome inactivation. | G-quadruplex folding in Xist RNA antagonizes PRC2 activity for stepwise regulation of X chromosome inactivation. Lee YW, Weissbein U, Blum R, Lee JT., | 08/16/2024 |
YY1 binding is a gene-intrinsic barrier to Xist-mediated gene silencing. | YY1 binding is a gene-intrinsic barrier to Xist-mediated gene silencing. Bowness JS, Almeida M, Nesterova TB, Brockdorff N., Free PMC Article | 07/16/2024 |
Long noncoding RNA XIST inhibition promotes Leydig cell apoptosis by acting as a competing endogenous RNA for microRNA-145a-5p that targets SIRT1 in late-onset hypogonadism. | Long noncoding RNA XIST inhibition promotes Leydig cell apoptosis by acting as a competing endogenous RNA for microRNA-145a-5p that targets SIRT1 in late-onset hypogonadism. Wang J, Yang Y, Xu Y, Xu Z, Zhao X, Jia R, Dai Y. | 03/1/2024 |
Xist ribonucleoproteins promote female sex-biased autoimmunity. | Xist ribonucleoproteins promote female sex-biased autoimmunity. Dou DR, Zhao Y, Belk JA, Zhao Y, Casey KM, Chen DC, Li R, Yu B, Srinivasan S, Abe BT, Kraft K, Hellström C, Sjöberg R, Chang S, Feng A, Goldman DW, Shah AA, Petri M, Chung LS, Fiorentino DF, Lundberg EK, Wutz A, Utz PJ, Chang HY., | 02/6/2024 |
Gender dimorphism in hepatocarcinogenesis-DNA methylation modification regulated X-chromosome inactivation escape molecule XIST. | Gender dimorphism in hepatocarcinogenesis-DNA methylation modification regulated X-chromosome inactivation escape molecule XIST. Dai Z, Wang S, Guo X, Wang Y, Yin H, Tan J, Mu C, Sun SH, Liu H, Yang F., Free PMC Article | 01/4/2024 |
GATA transcription factors drive initial Xist upregulation after fertilization through direct activation of long-range enhancers. | GATA transcription factors drive initial Xist upregulation after fertilization through direct activation of long-range enhancers. Ravid Lustig L, Sampath Kumar A, Schwämmle T, Dunkel I, Noviello G, Limberg E, Weigert R, Pacini G, Buschow R, Ghauri A, Stötzel M, Wittler L, Meissner A, Schulz EG., Free PMC Article | 11/16/2023 |
IncRNA XIST Promotes Cardiac Fibrosis in Mice with Diabetic Nephropathy via Sponging miR-106a-5p to Target RUNX1. | IncRNA XIST Promotes Cardiac Fibrosis in Mice with Diabetic Nephropathy via Sponging miR-106a-5p to Target RUNX1. Xu J, Li J, Xu X, Chen P, Wang Q, Li A, Ren Y. | 02/10/2023 |
LncRNA XIST promotes mitochondrial dysfunction of hepatocytes to aggravate hepatic fibrogenesis via miR-539-3p/ADAMTS5 axis. | LncRNA XIST promotes mitochondrial dysfunction of hepatocytes to aggravate hepatic fibrogenesis via miR-539-3p/ADAMTS5 axis. Wu XJ, Xie Y, Gu XX, Zhu HY, Huang LX. | 02/4/2023 |
XIST silencing alleviated inflammation and mesangial cells proliferation in diabetic nephropathy by sponging miR-485. | XIST silencing alleviated inflammation and mesangial cells proliferation in diabetic nephropathy by sponging miR-485. Wang Q. | 10/29/2022 |
Extracellular vesicle expansion of PMIS-miR-210 expression inhibits colorectal tumour growth via apoptosis and an XIST/NME1 regulatory mechanism. | Extracellular vesicle expansion of PMIS-miR-210 expression inhibits colorectal tumour growth via apoptosis and an XIST/NME1 regulatory mechanism. Eliason S, Hong L, Sweat Y, Chalkley C, Cao H, Liu Q, Qi H, Xu H, Zhan F, Amendt BA., Free PMC Article | 10/8/2022 |
Adipose-derived stem cells-derived exosomes facilitate cutaneous wound healing by delivering XIST and restoring discoidin domain receptor 2. | Adipose-derived stem cells-derived exosomes facilitate cutaneous wound healing by delivering XIST and restoring discoidin domain receptor 2. Zhu J, Quan H. | 09/24/2022 |
Negative pressure promotes macrophage M1 polarization after Mycobacterium tuberculosis infection via the lncRNA XIST/microRNA-125b-5p/A20/NF-kappaB axis. | Negative pressure promotes macrophage M1 polarization after Mycobacterium tuberculosis infection via the lncRNA XIST/microRNA-125b-5p/A20/NF-κB axis. Luo XB, Li LT, Xi JC, Liu HT, Liu Z, Yu L, Tang PF. | 09/3/2022 |
Xist exerts gene-specific silencing during XCI maintenance and impacts lineage-specific cell differentiation and proliferation during hematopoiesis. | Xist exerts gene-specific silencing during XCI maintenance and impacts lineage-specific cell differentiation and proliferation during hematopoiesis. Yang T, Ou J, Yildirim E., Free PMC Article | 08/6/2022 |
Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation. | Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation. Wanigasuriya I, Kinkel SA, Beck T, Roper EA, Breslin K, Lee HJ, Keniry A, Ritchie ME, Blewitt ME, Gouil Q., Free PMC Article | 07/30/2022 |
lncRNA XIST induces Abeta accumulation and neuroinflammation by the epigenetic repression of NEP in Alzheimer's disease. | lncRNA XIST induces Aβ accumulation and neuroinflammation by the epigenetic repression of NEP in Alzheimer's disease. Yan XW, Liu HJ, Hong YX, Meng T, Du J, Chang C. | 06/18/2022 |
Activation of Xist by an evolutionarily conserved function of KDM5C demethylase. | Activation of Xist by an evolutionarily conserved function of KDM5C demethylase. Samanta MK, Gayen S, Harris C, Maclary E, Murata-Nakamura Y, Malcore RM, Porter RS, Garay PM, Vallianatos CN, Samollow PB, Iwase S, Kalantry S., Free PMC Article | 06/11/2022 |
Mechanism of LncRNA XIST/ miR-101-3p/ZEB1 axis in EMT associated with silicosis. | Mechanism of LncRNA XIST/ miR-101-3p/ZEB1 axis in EMT associated with silicosis. Li C, Xia J, Yao W, Yang G, Tian Y, Qi Y, Hao C. | 04/16/2022 |
LncRNA XIST Prevents Tendon Adhesion and Promotes Tendon Repair Through the miR-26a-5p/COX2 Pathway. | LncRNA XIST Prevents Tendon Adhesion and Promotes Tendon Repair Through the miR-26a-5p/COX2 Pathway. Chen Q, Hou D, Suo Y, Zhu Z. | 04/9/2022 |
LncRNA XIST restrains the activation of Muller cells and inflammation in diabetic retinopathy via stabilizing SIRT1. | LncRNA XIST restrains the activation of Müller cells and inflammation in diabetic retinopathy via stabilizing SIRT1. Zhang J, Chen C, Zhang S, Chen J, Wu L, Chen Z. | 04/2/2022 |
Long noncoding RNA XIST regulates brown preadipocytes differentiation and combats high-fat diet induced obesity by targeting C/EBPalpha. | Long noncoding RNA XIST regulates brown preadipocytes differentiation and combats high-fat diet induced obesity by targeting C/EBPα. Wu C, Fang S, Zhang H, Li X, Du Y, Zhang Y, Lin X, Wang L, Ma X, Xue Y, Guan M., Free PMC Article | 04/2/2022 |
Knockdown of XIST up-regulates 263294miR-340-5p to relieve myocardial ischaemia-reperfusion injury via inhibiting cyclin D1. | Knockdown of XIST up-regulates 263294miR-340-5p to relieve myocardial ischaemia-reperfusion injury via inhibiting cyclin D1. Bai Q, Li Y, Song K, Huang J, Qin L., Free PMC Article | 04/2/2022 |
Haploid mouse germ cell precursors from embryonic stem cells reveal Xist activation from a single X chromosome. | Haploid mouse germ cell precursors from embryonic stem cells reveal Xist activation from a single X chromosome. Aizawa E, Kaufmann C, Sting S, Boigner S, Freimann R, Di Minin G, Wutz A., Free PMC Article | 03/26/2022 |
LncRNA XIST facilitates S1P-mediated osteoclast differentiation via interacting with FUS. | LncRNA XIST facilitates S1P-mediated osteoclast differentiation via interacting with FUS. Zhang DW, Wang HG, Zhang KB, Guo YQ, Yang LJ, Lv H. | 03/19/2022 |
XIST Inhibition Attenuates Calcium Oxalate Nephrocalcinosis-Induced Renal Inflammation and Oxidative Injury via the miR-223/NLRP3 Pathway. | XIST Inhibition Attenuates Calcium Oxalate Nephrocalcinosis-Induced Renal Inflammation and Oxidative Injury via the miR-223/NLRP3 Pathway. Lv P, Liu H, Ye T, Yang X, Duan C, Yao X, Li B, Tang K, Chen Z, Liu J, Deng Y, Wang T, Xing J, Liang C, Xu H, Ye Z., Free PMC Article | 02/19/2022 |
Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus. | Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus. Gjaltema RAF, Schwämmle T, Kautz P, Robson M, Schöpflin R, Ravid Lustig L, Brandenburg L, Dunkel I, Vechiatto C, Ntini E, Mutzel V, Schmiedel V, Marsico A, Mundlos S, Schulz EG. | 02/19/2022 |