| Platelet Microparticle-Derived MiR-320b Inhibits Hypertension with Atherosclerosis Development by Targeting ETFA. | Platelet Microparticle-Derived MiR-320b Inhibits Hypertension with Atherosclerosis Development by Targeting ETFA.
He Y, Jiang Y, Wu F, Zhang X, Liang S, Ye Z. | 04/2/2024 |
| NBPF4 mitigates progression in colorectal cancer through the regulation of EZH2-associated ETFA. | NBPF4 mitigates progression in colorectal cancer through the regulation of EZH2-associated ETFA.
Chen W, Di Z, Chen Z, Nan K, Gu J, Ge F, Liu J, Zhang H, Miao C., Free PMC Article | 02/26/2022 |
| Screening of multiple acyl-CoA dehydrogenase deficiency in newborns and follow-up of patients. | Screening of multiple acyl-CoA dehydrogenase deficiency in newborns and follow-up of patients.
Zhou D, Ye M, Hu Z, Zhang Y, Zhu L, Yang R, Huang X., Free PMC Article | 11/6/2021 |
| A case report of a mild form of multiple acyl-CoA dehydrogenase deficiency due to compound heterozygous mutations in the ETFA gene. | A case report of a mild form of multiple acyl-CoA dehydrogenase deficiency due to compound heterozygous mutations in the ETFA gene.
Chautard R, Laroche-Raynaud C, Lia AS, Chazelas P, Derouault P, Sturtz F, Baaj Y, Veauville-Merllié A, Acquaviva C, Favreau F, Faye PA., Free PMC Article | 12/19/2020 |
| Molecular Oxygen Binding in the Mitochondrial Electron Transfer Flavoprotein. | Molecular Oxygen Binding in the Mitochondrial Electron Transfer Flavoprotein.
Husen P, Nielsen C, Martino CF, Solov'yov IA. | 10/10/2020 |
| Molecular and Clinical Investigations on Portuguese Patients with Multiple acyl-CoA Dehydrogenase Deficiency. | Molecular and Clinical Investigations on Portuguese Patients with Multiple acyl-CoA Dehydrogenase Deficiency.
Henriques BJ, Lucas TG, Martins E, Gaspar A, Bandeira A, Nogueira C, Brandão O, Rocha H, Vilarinho L, Gomes CM. | 08/22/2020 |
| Data suggest that ETF (heterodimer of ETFA and ETFB) catalyzes irreversible and pH-dependent oxidation of 8alpha-methyl group of FAD to form to 8-formyl-FAD (8f-FAD). | Oxidation of the FAD cofactor to the 8-formyl-derivative in human electron-transferring flavoprotein.
Augustin P, Toplak M, Fuchs K, Gerstmann EC, Prassl R, Winkler A, Macheroux P., Free PMC Article | 12/26/2018 |
| our results indicate that genetic variants in ETFA may modify individual susceptibility to non-GBM of glioma in the Han Chinese population and support the role of the ETFA genes in the occurrence of glioma. | Additional evidence supports association of common genetic variants in VTI1A and ETFA with increased risk of glioma susceptibility.
Wang N, Deng Z, Wang M, Li R, Xu G, Bao G. | 07/8/2017 |
| the mechanism of tert-butyl hydroperoxide-induced an apoptosis cascade and endoplasmic reticulum stress in hepatocyte cells by up-regulation of ETFA, providing a new mechanism for liver injury. | Exploring the effects of tert-butylhydroperoxide induced liver injury using proteomic approach.
Shen CH, Tung SY, Huang WS, Lu CC, Lee KC, Hsieh YY, Chang PJ, Liang HF, Chen JH, Lin TH, Hsieh MC, Kuo HC. | 04/19/2014 |
| These results are consistent with the electron transfer flavoprotein alpha II domain adopting orientations in solution that deviate from the crystal structure of free ETF towards the active, substrate-bound orientation. | Electron transfer flavoprotein domain II orientation monitored using double electron-electron resonance between an enzymatically reduced, native FAD cofactor, and spin labels.
Swanson MA, Kathirvelu V, Majtan T, Frerman FE, Eaton GR, Eaton SS., Free PMC Article | 07/16/2011 |
| investigations are compatible with the notion that the ETFalpha-T171 variant displays an altered conformational landscape that results in reduced protein function under thermal stress | A polymorphic position in electron transfer flavoprotein modulates kinetic stability as evidenced by thermal stress.
Henriques BJ, Fisher MT, Bross P, Gomes CM. | 03/19/2011 |
| Data established structural hotspots within the ETF fold, and provided a rationale for the prediction of effects of mutations in ETF. | Mutational hotspots in electron transfer flavoprotein underlie defective folding and function in multiple acyl-CoA dehydrogenase deficiency.
Henriques BJ, Bross P, Gomes CM. | 12/11/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesGenetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ. Clinical and genetic analysis of lipid storage myopathies.
Ohkuma A, Noguchi S, Sugie H, Malicdan MC, Fukuda T, Shimazu K, López LC, Hirano M, Hayashi YK, Nonaka I, Nishino I. | 03/25/2009 |
| No mutations in electron-transfer-flavoprotein but maternal riboflavin deficiency led to multiple acyl-CoA dehydrogenation deficiency | Transient multiple acyl-CoA dehydrogenation deficiency in a newborn female caused by maternal riboflavin deficiency.
Chiong MA, Sim KG, Carpenter K, Rhead W, Ho G, Olsen RK, Christodoulou J. | 01/21/2010 |
| These studies indicate that a series of conformational changes occur during the assembly of the TMADH.ETF electron transfer complex and that the kinetics of assembly observed with mutant TMADH or ETF complexes are much slower | Electron transfer and conformational change in complexes of trimethylamine dehydrogenase and electron transferring flavoprotein.
Jones M, Talfournier F, Bobrov A, Grossmann JG, Vekshin N, Sutcliffe MJ, Scrutton NS. | 01/21/2010 |
| Tissue samples from 16 unrelated patients with ETF deficiency were analysed and the majority of the patients had mutations in the ETFA gene. | Electron transfer flavoprotein deficiency: functional and molecular aspects.
Schiff M, Froissart R, Olsen RK, Acquaviva C, Vianey-Saban C. | 01/21/2010 |