| Functional pathogenicity of ESRRB variant of uncertain significance contributes to hearing loss (DFNB35). | Functional pathogenicity of ESRRB variant of uncertain significance contributes to hearing loss (DFNB35).
Choi WH, Cho Y, Cha JH, Lee DH, Jeong JG, Jung SH, Song JJ, Lee JH, Lee SY., Free PMC Article | 09/12/2024 |
| SIRT1 mediates breast cancer development and tumorigenesis controlled by estrogen-related receptor beta. | SIRT1 mediates breast cancer development and tumorigenesis controlled by estrogen-related receptor β.
Parija M, Prakash S, Krishna BM, Dash S, Mishra SK. | 05/2/2024 |
| Long Noncoding RNA ACTA2-AS1 Inhibits Cell Growth and Facilitates Apoptosis in Gastric Cancer by Binding with miR-6720-5p to Regulate ESRRB. | Long Noncoding RNA ACTA2-AS1 Inhibits Cell Growth and Facilitates Apoptosis in Gastric Cancer by Binding with miR-6720-5p to Regulate ESRRB.
Hu Z, Chen Z, Jiang W, Fang D, Peng P, Yao S, Luo M, Wang L, Sun Z, Wang W, Wang X, Mao H, Ai F, Zhou P. | 11/28/2023 |
| ESRRB Inhibits the TGFbeta Signaling Pathway to Drive Cell Proliferation in Cervical Cancer. | ESRRB Inhibits the TGFβ Signaling Pathway to Drive Cell Proliferation in Cervical Cancer.
Li QS, Zheng PS., Free PMC Article | 09/20/2023 |
| A novel missense variant in ESRRB gene causing autosomal recessive non-syndromic hearing loss: in silico analysis of a case. | A novel missense variant in ESRRB gene causing autosomal recessive non-syndromic hearing loss: in silico analysis of a case.
Ghasemnejad T, Shekari Khaniani M, Nouri Nojadeh J, Mansoori Derakhshan S., Free PMC Article | 04/16/2022 |
| Estrogen-related receptors: novel potential regulators of osteoarthritis pathogenesis. | Estrogen-related receptors: novel potential regulators of osteoarthritis pathogenesis.
Tang J, Liu T, Wen X, Zhou Z, Yan J, Gao J, Zuo J., Free PMC Article | 10/2/2021 |
| Expression of estrogen-related receptors in ovarian cancer and impact on survival. | Expression of estrogen-related receptors in ovarian cancer and impact on survival.
Schüler-Toprak S, Weber F, Skrzypczak M, Ortmann O, Treeck O., Free PMC Article | 08/21/2021 |
| ESRRB regulates glucocorticoid gene expression in mice and patients with acute lymphoblastic leukemia. | ESRRB regulates glucocorticoid gene expression in mice and patients with acute lymphoblastic leukemia.
Gallagher KM, Roderick JE, Tan SH, Tan TK, Murphy L, Yu J, Li R, O'Connor KW, Zhu J, Green MR, Sanda T, Kelliher MA., Free PMC Article | 05/22/2021 |
| Structural Insights into the Specificity of Ligand Binding and Coactivator Assembly by Estrogen-Related Receptor beta. | Structural Insights into the Specificity of Ligand Binding and Coactivator Assembly by Estrogen-Related Receptor β.
Yao B, Zhang S, Wei Y, Tian S, Lu Z, Jin L, He Y, Xie W, Li Y. | 03/13/2021 |
| The orphan nuclear receptor Esrrb plays a pioneering role in recruiting the core pluripotency factors Oct4, Sox2, and Nanog to inactive enhancers in closed chromatin during the reprogramming of epiblast stem cells. | Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency.
Adachi K, Kopp W, Wu G, Heising S, Greber B, Stehling M, Araúzo-Bravo MJ, Boerno ST, Timmermann B, Vingron M, Schöler HR. | 10/5/2019 |
| For the ESRRB (rs1676303) gene, an association was observed between the CC (cytosine/cytosine) genotype and the presence of articular TMDs associated with other chronic arthralgia (P = .02). | Association Between Polymorphisms in the Genes of Estrogen Receptors and the Presence of Temporomandibular Disorders and Chronic Arthralgia.
Quinelato V, Bonato LL, Vieira AR, Granjeiro JM, Tesch R, Casado PL. | 04/27/2019 |
| EZH2 as a relevant coregulator for estrogen-related receptors alpha, beta and gamma in breast carcinoma. | Estrogen-related receptors alpha, beta and gamma expression and function is associated with transcriptional repressor EZH2 in breast carcinoma.
Kumari K, Adhya AK, Rath AK, Reddy PB, Mishra SK., Free PMC Article | 02/2/2019 |
| Esrrb activity at crucial regulatory elements of the pluripotency network, coupled with its role as a mitotic bookmarking factor and the ability to reset cellular metabolism, might explain its potent functions in ensuring the stability of pluripotency and driving the late stages of reprogramming. | Esrrb, an estrogen-related receptor involved in early development, pluripotency, and reprogramming.
Festuccia N, Owens N, Navarro P. | 01/26/2019 |
| rs12437118 associated with tuberculosis risk in Han Chinese | Genome-wide association study identifies two risk loci for tuberculosis in Han Chinese.
Zheng R, Li Z, He F, Liu H, Chen J, Chen J, Xie X, Zhou J, Chen H, Wu X, Wu J, Chen B, Liu Y, Cui H, Fan L, Sha W, Liu Y, Wang J, Huang X, Zhang L, Xu F, Wang J, Feng Y, Qin L, Yang H, Liu Z, Cui Z, Liu F, Chen X, Gao S, Sun S, Shi Y, Ge B., Free PMC Article | 01/26/2019 |
| Study results indicate that ERRbeta is a negative regulator of cell cycle and a possible tumor suppressor in breast cancer. | Estrogen receptor α dependent regulation of estrogen related receptor β and its role in cell cycle in breast cancer.
Madhu Krishna B, Chaudhary S, Mishra DR, Naik SK, Suklabaidya S, Adhya AK, Mishra SK., Free PMC Article | 01/19/2019 |
| the calcium level was associated with genetic variations in AMELX, AMNB and ESRRB. AMELX and AMNB are involved in enamel mineralization. Mutations in both these genes are responsible for the amelogenesis imperfecta phenotype (OMIN), which supports their link with enamel alterations as well as enamel mineralization. | Genes Involved in the Enamel Development Are Associated with Calcium and Phosphorus Level in Saliva.
Küchler EC, Pecharki GD, Castro ML, Ramos J, Barbosa F Jr, Brancher JA, Vieira AR, Gerlach RF, Trevilatto PC., Free PMC Article | 06/30/2018 |
| SNP (rs61742642; C to T, P386S) in the ligand-binding domain of human estrogen-related receptor beta is associated with audiometric temporary threshold shift. | A polymorphism in human estrogen-related receptor beta (ESRRβ) predicts audiometric temporary threshold shift.
Bhatt I, Phillips S, Richter S, Tucker D, Lundgren K, Morehouse R, Henrich V., Free PMC Article | 12/2/2017 |
| ESRRbeta is mislocalized in human myocardium samples with idiopathic dilated cardiomyopathy, suggesting a possible role for ESRRbeta in the pathogenesis of idiopathic dilated cardiomyopathy in humans | Development of dilated cardiomyopathy and impaired calcium homeostasis with cardiac-specific deletion of ESRRβ.
Rowe GC, Asimaki A, Graham EL, Martin KD, Margulies KB, Das S, Saffitz J, Arany Z., Free PMC Article | 07/29/2017 |
| The rs1676303 TT (P=0.02) and rs6574293 GG (P=0.04) genotypes of ESRRB were associated with RCD and TMD, respectively. | ESRRB polymorphisms are associated with comorbidity of temporomandibular disorders and rotator cuff disease.
Bonato LL, Quinelato V, Pinheiro Ada R, Amaral MV, de Souza FN, Lobo JC, Aguiar DP, Augusto LM, Vieira AR, Salles JI, Cossich VR, Guimarães JA, de Gouvêa CV, Granjeiro JM, Casado PL. | 12/24/2016 |
| analysis of Esrrb target genes indicates Esrrb may be an important factor in regulating cell proliferation | Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells.
Lu Y, Li J, Cheng J, Lubahn DB., Free PMC Article | 08/6/2016 |
| ERRbeta has a role in estrogen-dependent cellular function including cancer cell proliferation | Estrogen-related Receptor β Reduces the Subnuclear Mobility of Estrogen Receptor α and Suppresses Estrogen-dependent Cellular Function.
Tanida T, Matsuda KI, Yamada S, Hashimoto T, Kawata M., Free PMC Article | 08/8/2015 |
| The significant association and the presence of high-risk haplotypes identified in the ESRRB gene confirm the association of variants in ESRRB and rotator cuff disease. | Significant association of full-thickness rotator cuff tears and estrogen-related receptor-β (ESRRB).
Teerlink CC, Cannon-Albright LA, Tashjian RZ. | 06/20/2015 |
| study concludes ESRRB, a gene when mutated causes a form of hearing impairment, also contributes to dental decay likely by influencing the formation of an enamel surface more susceptible to demineralization under acidic conditions | Role of estrogen related receptor beta (ESRRB) in DFN35B hearing impairment and dental decay.
Weber ML, Hsin HY, Kalay E, BroŽková DS, Shimizu T, Bayram M, Deeley K, Küchler EC, Forella J, Ruff TD, Trombetta VM, Sencak RC, Hummel M, Briseño-Ruiz J, Revu SK, Granjeiro JM, Antunes LS, Antunes LA, Abreu FV, Costa MC, Tannure PN, Koruyucu M, Patir A, Poletta FA, Mereb JC, Castilla EE, Orioli IM, Marazita ML, Ouyang H, Jayaraman T, Seymen F, Vieira AR., Free PMC Article | 09/13/2014 |
| ERRbeta signalling leads to BCAS2-mediated blockage of the G1/S transition and inhibition of the epithelial to mesenchymal transition through FST-mediated regulation of E-cadherin | ERRβ signalling through FST and BCAS2 inhibits cellular proliferation in breast cancer cells.
Sengupta D, Bhargava DK, Dixit A, Sahoo BS, Biswas S, Biswas G, Mishra SK., Free PMC Article | 06/7/2014 |
| This is the first report of DFNB35 mutations in the Czech Republic and it seems to be a rare cause of non-syndromic hearing loss. | DFNB35 due to a novel mutation in the ESRRB gene in a Czech consanguineous family.
Šafka Brožková D, Laštůvková J, Machalová E, Lisoňová J, Trková M, Seeman P. | 05/25/2013 |