ERG Regulates Lymphatic Vessel Specification Genes and Its Deficiency Impairs Wound Healing-Associated Lymphangiogenesis. | ERG Regulates Lymphatic Vessel Specification Genes and Its Deficiency Impairs Wound Healing-Associated Lymphangiogenesis. Yamashita T, Kaplan U, Chakraborty A, Marden G, Gritli S, Roh D, Bujor A, Trojanowski M, Ligresti G, Browning JL, Trojanowska M., | 11/7/2024 |
An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation. | An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation. Wang C, Hu M, Yu K, Liu W, Hu A, Kuang Y, Huang L, Gajendran B, Zacksenhaus E, Xiao X, Ben-David Y., Free PMC Article | 05/20/2024 |
NKX2-1-AS1 promotes the lymphangiogenesis of lung adenocarcinoma through regulation of ERG-mediated FABP4. | NKX2-1-AS1 promotes the lymphangiogenesis of lung adenocarcinoma through regulation of ERG-mediated FABP4. Tao T, Chen H, Xu Q, Li Z, Chen X, Zhou X, Luo W. | 03/20/2024 |
ERG and c-MYC regulate a critical gene network in BCR::ABL1-driven B cell acute lymphoblastic leukemia. | ERG and c-MYC regulate a critical gene network in BCR::ABL1-driven B cell acute lymphoblastic leukemia. Behrens K, Brajanovski N, Xu Z, Viney EM, DiRago L, Hediyeh-Zadeh S, Davis MJ, Pearson RB, Sanij E, Alexander WS, Ng AP., Free PMC Article | 03/15/2024 |
ERG mediates the inhibition of NK cell cytotoxicity through the HLX/STAT4/Perforin signaling pathway, thereby promoting the progression of myocardial infarction. | ERG mediates the inhibition of NK cell cytotoxicity through the HLX/STAT4/Perforin signaling pathway, thereby promoting the progression of myocardial infarction. Guo L, Wu D, Shen J, Gao Y. | 02/5/2024 |
A complex with poly(A)-binding protein and EWS facilitates the transcriptional function of oncogenic ETS transcription factors in prostate cells. | A complex with poly(A)-binding protein and EWS facilitates the transcriptional function of oncogenic ETS transcription factors in prostate cells. Greulich BM, Rajendran S, Downing NF, Nicholas TR, Hollenhorst PC., Free PMC Article | 01/31/2024 |
Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis. | Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis. Tang X, Huang J, Jiang Y, Qiu J, Li T, Li W, Chen Z, Huang Z, Yu X, Yang T, Ji X, Tan R, Lv L, Yang Z, Chen H., Free PMC Article | 09/29/2023 |
Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge. | Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge. Schafer CM, Martin-Almedina S, Kurylowicz K, Dufton N, Osuna-Almagro L, Wu ML, Johnson CF, Shah AV, Haskard DO, Buxton A, Willis E, Wheeler K, Turner S, Chlebicz M, Scott RP, Kovats S, Cleuren A, Birdsey GM, Randi AM, Griffin CT., Free PMC Article | 09/6/2023 |
Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis. | Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis. Ding D, Blee AM, Zhang J, Pan Y, Becker NA, Maher LJ 3rd, Jimenez R, Wang L, Huang H., Free PMC Article | 08/7/2023 |
ERG Status at the Margin Is Associated With Biochemical Recurrence After Radical Prostatectomy With Positive Surgical Margins. | ERG Status at the Margin Is Associated With Biochemical Recurrence After Radical Prostatectomy With Positive Surgical Margins. Salles DC, Mendes AA, Han M, Partin AW, Trock BJ, Jing Y, Lotan TL., Free PMC Article | 07/31/2023 |
EVI1 exerts distinct roles in AML via ERG and cyclin D1 promoting a chemoresistant and immune-suppressive environment. | EVI1 exerts distinct roles in AML via ERG and cyclin D1 promoting a chemoresistant and immune-suppressive environment. Masamoto Y, Chiba A, Mizuno H, Hino T, Hayashida H, Sato T, Bando M, Shirahige K, Kurokawa M., Free PMC Article | 04/19/2023 |
Novel high-risk acute myeloid leukemia subgroup with ERG amplification and Biallelic loss of TP53. | Novel high-risk acute myeloid leukemia subgroup with ERG amplification and Biallelic loss of TP53. Schandl CA, Mazzoni S, Znoyko I, Nahhas GJ, Chung D, Ding Y, Hess B, Wolff DJ. | 03/21/2023 |
ERG Expression is Helpful in Differentiating T-Lymphoblastic Lymphoma from Thymoma. | ERG Expression is Helpful in Differentiating T-Lymphoblastic Lymphoma from Thymoma. Huang W, Zhang W, Zeng L, Liao S, Liu F, Li L. | 03/16/2023 |
ERG Functionally Overlaps with Other Ets Proteins in Promoting TH9 Cell Expression of Il9 during Allergic Lung Inflammation. | ERG Functionally Overlaps with Other Ets Proteins in Promoting TH9 Cell Expression of Il9 during Allergic Lung Inflammation. Kharwadkar R, Ulrich BJ, Chu M, Koh B, Hufford MM, Fu Y, Birdsey GM, Porse BT, Randi AM, Kaplan MH., Free PMC Article | 03/11/2023 |
In situ expression of ERG protein in the context of tumor heterogeneity identifies prostate cancer patients with inferior prognosis. | In situ expression of ERG protein in the context of tumor heterogeneity identifies prostate cancer patients with inferior prognosis. Kidd SG, Bogaard M, Carm KT, Bakken AC, Maltau AMV, Løvf M, Lothe RA, Axcrona K, Axcrona U, Skotheim RI., Free PMC Article | 08/13/2022 |
A novel HNRNPH1::ERG rearrangement in aggressive acute myeloid leukemia. | A novel HNRNPH1::ERG rearrangement in aggressive acute myeloid leukemia. Jiang F, Lang X, Chen N, Jin L, Liu L, Wei X, Pan J, Yu F, Blake A, Xiao S. | 06/25/2022 |
The Expression of Proto-Oncogene ETS-Related Gene (ERG) Plays a Central Role in the Oncogenic Mechanism Involved in the Development and Progression of Prostate Cancer. | The Expression of Proto-Oncogene ETS-Related Gene (ERG) Plays a Central Role in the Oncogenic Mechanism Involved in the Development and Progression of Prostate Cancer. Khosh Kish E, Choudhry M, Gamallat Y, Buharideen SM, D D, Bismar TA., Free PMC Article | 05/21/2022 |
PGC1 alpha coactivates ERG fusion to drive antioxidant target genes under metabolic stress. | PGC1 alpha coactivates ERG fusion to drive antioxidant target genes under metabolic stress. Dhara A, Aier I, Paladhi A, Varadwaj PK, Hira SK, Sen N., Free PMC Article | 05/14/2022 |
Splice variants denote differences between a cancer stem cell side population of EWSR1ERGbased Ewing sarcoma cells, its main population and EWSR1FLIbased cells. | Splice variants denote differences between a cancer stem cell side population of EWSR1‑ERG‑based Ewing sarcoma cells, its main population and EWSR1‑FLI‑based cells. Korsching E, Matschke J, Hotfilder M., Free PMC Article | 04/9/2022 |
ERG Immunoreactivity in Blastic Hematolymphoid Neoplasms: Diagnostic Pitfall in the Workup of Undifferentiated Malignant Neoplasms. | ERG Immunoreactivity in Blastic Hematolymphoid Neoplasms: Diagnostic Pitfall in the Workup of Undifferentiated Malignant Neoplasms. Koo M, Natkunam Y. | 03/19/2022 |
Immunohistochemical expression of the ERG gene in prostatic adenocarcinoma and its relationship with clinicopathological parameters. | Immunohistochemical expression of the ERG gene in prostatic adenocarcinoma and its relationship with clinicopathological parameters. Birol IE, Bahadir B, Ozdamar SO, Kaymaz E, Girgin R. | 03/19/2022 |
ETS-Related Gene Activation Preserves Adherens Junctions and Permeability in Microvascular Endothelial Cells. | ETS-Related Gene Activation Preserves Adherens Junctions and Permeability in Microvascular Endothelial Cells. Tharakan B, Hunter FA, Muthusamy S, Randolph S, Byrd C, Rao VN, Reddy ESP, Childs EW. | 03/12/2022 |
Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O'PROTAC): Effective Targeting of LEF1 and ERG. | Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O'PROTAC): Effective Targeting of LEF1 and ERG. Shao J, Yan Y, Ding D, Wang D, He Y, Pan Y, Yan W, Kharbanda A, Li HY, Huang H., Free PMC Article | 02/26/2022 |
Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states. | Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states. Song H, Weinstein HNW, Allegakoen P, Wadsworth MH 2nd, Xie J, Yang H, Castro EA, Lu KL, Stohr BA, Feng FY, Carroll PR, Wang B, Cooperberg MR, Shalek AK, Huang FW., Free PMC Article | 01/29/2022 |
Association of Prediagnostic Blood Metabolomics with Prostate Cancer Defined by ERG or PTEN Molecular Subtypes. | Association of Prediagnostic Blood Metabolomics with Prostate Cancer Defined by ERG or PTEN Molecular Subtypes. Feng X, Zhou CK, Clish CB, Wilson KM, Pernar CH, Dickerman BA, Loda M, Finn SP, Penney KL, Schmidt DR, Vander Heiden MG, Giovannucci EL, Ebot EM, Mucci LA., Free PMC Article | 01/15/2022 |