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    ERG ETS transcription factor ERG [ Homo sapiens (human) ]

    Gene ID: 2078, updated on 12-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    ERG Regulates Lymphatic Vessel Specification Genes and Its Deficiency Impairs Wound Healing-Associated Lymphangiogenesis.

    ERG Regulates Lymphatic Vessel Specification Genes and Its Deficiency Impairs Wound Healing-Associated Lymphangiogenesis.
    Yamashita T, Kaplan U, Chakraborty A, Marden G, Gritli S, Roh D, Bujor A, Trojanowski M, Ligresti G, Browning JL, Trojanowska M.,

    11/7/2024
    An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation.

    An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation.
    Wang C, Hu M, Yu K, Liu W, Hu A, Kuang Y, Huang L, Gajendran B, Zacksenhaus E, Xiao X, Ben-David Y., Free PMC Article

    05/20/2024
    NKX2-1-AS1 promotes the lymphangiogenesis of lung adenocarcinoma through regulation of ERG-mediated FABP4.

    NKX2-1-AS1 promotes the lymphangiogenesis of lung adenocarcinoma through regulation of ERG-mediated FABP4.
    Tao T, Chen H, Xu Q, Li Z, Chen X, Zhou X, Luo W.

    03/20/2024
    ERG and c-MYC regulate a critical gene network in BCR::ABL1-driven B cell acute lymphoblastic leukemia.

    ERG and c-MYC regulate a critical gene network in BCR::ABL1-driven B cell acute lymphoblastic leukemia.
    Behrens K, Brajanovski N, Xu Z, Viney EM, DiRago L, Hediyeh-Zadeh S, Davis MJ, Pearson RB, Sanij E, Alexander WS, Ng AP., Free PMC Article

    03/15/2024
    ERG mediates the inhibition of NK cell cytotoxicity through the HLX/STAT4/Perforin signaling pathway, thereby promoting the progression of myocardial infarction.

    ERG mediates the inhibition of NK cell cytotoxicity through the HLX/STAT4/Perforin signaling pathway, thereby promoting the progression of myocardial infarction.
    Guo L, Wu D, Shen J, Gao Y.

    02/5/2024
    A complex with poly(A)-binding protein and EWS facilitates the transcriptional function of oncogenic ETS transcription factors in prostate cells.

    A complex with poly(A)-binding protein and EWS facilitates the transcriptional function of oncogenic ETS transcription factors in prostate cells.
    Greulich BM, Rajendran S, Downing NF, Nicholas TR, Hollenhorst PC., Free PMC Article

    01/31/2024
    Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis.

    Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis.
    Tang X, Huang J, Jiang Y, Qiu J, Li T, Li W, Chen Z, Huang Z, Yu X, Yang T, Ji X, Tan R, Lv L, Yang Z, Chen H., Free PMC Article

    09/29/2023
    Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge.

    Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge.
    Schafer CM, Martin-Almedina S, Kurylowicz K, Dufton N, Osuna-Almagro L, Wu ML, Johnson CF, Shah AV, Haskard DO, Buxton A, Willis E, Wheeler K, Turner S, Chlebicz M, Scott RP, Kovats S, Cleuren A, Birdsey GM, Randi AM, Griffin CT., Free PMC Article

    09/6/2023
    Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis.

    Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis.
    Ding D, Blee AM, Zhang J, Pan Y, Becker NA, Maher LJ 3rd, Jimenez R, Wang L, Huang H., Free PMC Article

    08/7/2023
    ERG Status at the Margin Is Associated With Biochemical Recurrence After Radical Prostatectomy With Positive Surgical Margins.

    ERG Status at the Margin Is Associated With Biochemical Recurrence After Radical Prostatectomy With Positive Surgical Margins.
    Salles DC, Mendes AA, Han M, Partin AW, Trock BJ, Jing Y, Lotan TL., Free PMC Article

    07/31/2023
    EVI1 exerts distinct roles in AML via ERG and cyclin D1 promoting a chemoresistant and immune-suppressive environment.

    EVI1 exerts distinct roles in AML via ERG and cyclin D1 promoting a chemoresistant and immune-suppressive environment.
    Masamoto Y, Chiba A, Mizuno H, Hino T, Hayashida H, Sato T, Bando M, Shirahige K, Kurokawa M., Free PMC Article

    04/19/2023
    Novel high-risk acute myeloid leukemia subgroup with ERG amplification and Biallelic loss of TP53.

    Novel high-risk acute myeloid leukemia subgroup with ERG amplification and Biallelic loss of TP53.
    Schandl CA, Mazzoni S, Znoyko I, Nahhas GJ, Chung D, Ding Y, Hess B, Wolff DJ.

    03/21/2023
    ERG Expression is Helpful in Differentiating T-Lymphoblastic Lymphoma from Thymoma.

    ERG Expression is Helpful in Differentiating T-Lymphoblastic Lymphoma from Thymoma.
    Huang W, Zhang W, Zeng L, Liao S, Liu F, Li L.

    03/16/2023
    ERG Functionally Overlaps with Other Ets Proteins in Promoting TH9 Cell Expression of Il9 during Allergic Lung Inflammation.

    ERG Functionally Overlaps with Other Ets Proteins in Promoting TH9 Cell Expression of Il9 during Allergic Lung Inflammation.
    Kharwadkar R, Ulrich BJ, Chu M, Koh B, Hufford MM, Fu Y, Birdsey GM, Porse BT, Randi AM, Kaplan MH., Free PMC Article

    03/11/2023
    In situ expression of ERG protein in the context of tumor heterogeneity identifies prostate cancer patients with inferior prognosis.

    In situ expression of ERG protein in the context of tumor heterogeneity identifies prostate cancer patients with inferior prognosis.
    Kidd SG, Bogaard M, Carm KT, Bakken AC, Maltau AMV, Løvf M, Lothe RA, Axcrona K, Axcrona U, Skotheim RI., Free PMC Article

    08/13/2022
    A novel HNRNPH1::ERG rearrangement in aggressive acute myeloid leukemia.

    A novel HNRNPH1::ERG rearrangement in aggressive acute myeloid leukemia.
    Jiang F, Lang X, Chen N, Jin L, Liu L, Wei X, Pan J, Yu F, Blake A, Xiao S.

    06/25/2022
    The Expression of Proto-Oncogene ETS-Related Gene (ERG) Plays a Central Role in the Oncogenic Mechanism Involved in the Development and Progression of Prostate Cancer.

    The Expression of Proto-Oncogene ETS-Related Gene (ERG) Plays a Central Role in the Oncogenic Mechanism Involved in the Development and Progression of Prostate Cancer.
    Khosh Kish E, Choudhry M, Gamallat Y, Buharideen SM, D D, Bismar TA., Free PMC Article

    05/21/2022
    PGC1 alpha coactivates ERG fusion to drive antioxidant target genes under metabolic stress.

    PGC1 alpha coactivates ERG fusion to drive antioxidant target genes under metabolic stress.
    Dhara A, Aier I, Paladhi A, Varadwaj PK, Hira SK, Sen N., Free PMC Article

    05/14/2022
    Splice variants denote differences between a cancer stem cell side population of EWSR1ERGbased Ewing sarcoma cells, its main population and EWSR1FLIbased cells.

    Splice variants denote differences between a cancer stem cell side population of EWSR1‑ERG‑based Ewing sarcoma cells, its main population and EWSR1‑FLI‑based cells.
    Korsching E, Matschke J, Hotfilder M., Free PMC Article

    04/9/2022
    ERG Immunoreactivity in Blastic Hematolymphoid Neoplasms: Diagnostic Pitfall in the Workup of Undifferentiated Malignant Neoplasms.

    ERG Immunoreactivity in Blastic Hematolymphoid Neoplasms: Diagnostic Pitfall in the Workup of Undifferentiated Malignant Neoplasms.
    Koo M, Natkunam Y.

    03/19/2022
    Immunohistochemical expression of the ERG gene in prostatic adenocarcinoma and its relationship with clinicopathological parameters.

    Immunohistochemical expression of the ERG gene in prostatic adenocarcinoma and its relationship with clinicopathological parameters.
    Birol IE, Bahadir B, Ozdamar SO, Kaymaz E, Girgin R.

    03/19/2022
    ETS-Related Gene Activation Preserves Adherens Junctions and Permeability in Microvascular Endothelial Cells.

    ETS-Related Gene Activation Preserves Adherens Junctions and Permeability in Microvascular Endothelial Cells.
    Tharakan B, Hunter FA, Muthusamy S, Randolph S, Byrd C, Rao VN, Reddy ESP, Childs EW.

    03/12/2022
    Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O'PROTAC): Effective Targeting of LEF1 and ERG.

    Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O'PROTAC): Effective Targeting of LEF1 and ERG.
    Shao J, Yan Y, Ding D, Wang D, He Y, Pan Y, Yan W, Kharbanda A, Li HY, Huang H., Free PMC Article

    02/26/2022
    Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states.

    Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states.
    Song H, Weinstein HNW, Allegakoen P, Wadsworth MH 2nd, Xie J, Yang H, Castro EA, Lu KL, Stohr BA, Feng FY, Carroll PR, Wang B, Cooperberg MR, Shalek AK, Huang FW., Free PMC Article

    01/29/2022
    Association of Prediagnostic Blood Metabolomics with Prostate Cancer Defined by ERG or PTEN Molecular Subtypes.

    Association of Prediagnostic Blood Metabolomics with Prostate Cancer Defined by ERG or PTEN Molecular Subtypes.
    Feng X, Zhou CK, Clish CB, Wilson KM, Pernar CH, Dickerman BA, Loda M, Finn SP, Penney KL, Schmidt DR, Vander Heiden MG, Giovannucci EL, Ebot EM, Mucci LA., Free PMC Article

    01/15/2022
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