| CircMAP3K4 Suppresses H2O2-Induced Human Lens Epithelial Cell Injury by miR-630/ERCC6 Axis in Age-Related Cataract. | CircMAP3K4 Suppresses H2O2-Induced Human Lens Epithelial Cell Injury by miR-630/ERCC6 Axis in Age-Related Cataract.
Cui F, Sun Z, Zhang X, Liu C. | 04/23/2024 |
| The CSB chromatin remodeler regulates PARP1- and PARP2-mediated single-strand break repair at actively transcribed DNA regions. | The CSB chromatin remodeler regulates PARP1- and PARP2-mediated single-strand break repair at actively transcribed DNA regions.
Bilkis R, Lake RJ, Cooper KL, Tomkinson A, Fan HY., Free PMC Article | 08/14/2023 |
| ERCC6 plays a promoting role in the progression of non-small cell lung cancer. | ERCC6 plays a promoting role in the progression of non-small cell lung cancer.
Luo H, Xiao Z, Huang C, Wu W, Xie Q. | 06/13/2023 |
| A novel heterozygous ERCC6 variant identified in a Chinese family with non-syndromic primary ovarian insufficiency. | A novel heterozygous ERCC6 variant identified in a Chinese family with non-syndromic primary ovarian insufficiency.
Kuang L, Liu B, Xi D, Gao Y., Free PMC Article | 10/15/2022 |
| Genetic pleiotropy of ERCC6 loss-of-function and deleterious missense variants links retinal dystrophy, arrhythmia, and immunodeficiency in diverse ancestries. | Genetic pleiotropy of ERCC6 loss-of-function and deleterious missense variants links retinal dystrophy, arrhythmia, and immunodeficiency in diverse ancestries.
Forrest IS, Chaudhary K, Vy HMT, Bafna S, Kim S, Won HH, Loos RJF, Cho J, Pasquale LR, Nadkarni GN, Rocheleau G, Do R., Free PMC Article | 07/16/2022 |
| Genetic Association of ERCC6 rs2228526 Polymorphism with the Risk of Cancer: Evidence from a Meta-Analysis. | Genetic Association of ERCC6 rs2228526 Polymorphism with the Risk of Cancer: Evidence from a Meta-Analysis.
Lin X, Wu Y, Li Q, Yu H, Li X, Li X, Zheng J., Free PMC Article | 05/14/2022 |
| MicroRNA Let-7c-5p-Mediated Regulation of ERCC6 Disrupts Autophagic Flux in Age-Related Cataract via the Binding to VCP. | MicroRNA Let-7c-5p-Mediated Regulation of ERCC6 Disrupts Autophagic Flux in Age-Related Cataract via the Binding to VCP.
Cao Y, Li P, Zhang G, Kang L, Zhou T, Wu J, Wang Y, Wang Y, Chen X, Guan H. | 03/5/2022 |
| Profiling and Integrated Analysis of the ERCC6-regulated circRNA-miRNA-mRNA Network in Lens Epithelial Cells. | Profiling and Integrated Analysis of the ERCC6-regulated circRNA-miRNA-mRNA Network in Lens Epithelial Cells.
Wang Y, Zhang G, Li P, Kang L, Qin B, Cao Y, Luo J, Chen X, Qin M, Guan H. | 03/5/2022 |
| Identification and Characterization of a Novel Recurrent ERCC6 Variant in Patients with a Severe Form of Cockayne Syndrome B. | Identification and Characterization of a Novel Recurrent ERCC6 Variant in Patients with a Severe Form of Cockayne Syndrome B.
Zayoud K, Kraoua I, Chikhaoui A, Calmels N, Bouchoucha S, Obringer C, Crochemore C, Najjar D, Zarrouk S, Miladi N, Laugel V, Ricchetti M, Turki I, Yacoub-Youssef H., Free PMC Article | 02/19/2022 |
| Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells. | Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells.
Batenburg NL, Mersaoui SY, Walker JR, Coulombe Y, Hammond-Martel I, Wurtele H, Masson JY, Zhu XD., Free PMC Article | 01/15/2022 |
| Mechanism of Rad26-assisted rescue of stalled RNA polymerase II in transcription-coupled repair. | Mechanism of Rad26-assisted rescue of stalled RNA polymerase II in transcription-coupled repair.
Yan C, Dodd T, Yu J, Leung B, Xu J, Oh J, Wang D, Ivanov I., Free PMC Article | 01/1/2022 |
| Cockayne syndrome group A and ferrochelatase finely tune ribosomal gene transcription and its response to UV irradiation. | Cockayne syndrome group A and ferrochelatase finely tune ribosomal gene transcription and its response to UV irradiation.
Lanzafame M, Branca G, Landi C, Qiang M, Vaz B, Nardo T, Ferri D, Mura M, Iben S, Stefanini M, Peverali FA, Bini L, Orioli D., Free PMC Article | 12/25/2021 |
| Neuroblastoma Cells Depend on CSB for Faithful Execution of Cytokinesis and Survival. | Neuroblastoma Cells Depend on CSB for Faithful Execution of Cytokinesis and Survival.
Paccosi E, Costantino M, Balzerano A, Filippi S, Brancorsini S, Proietti-De-Santis L., Free PMC Article | 11/22/2021 |
| Cockayne Syndrome-Associated CSA and CSB Mutations Impair Ribosome Biogenesis, Ribosomal Protein Stability, and Global Protein Folding. | Cockayne Syndrome-Associated CSA and CSB Mutations Impair Ribosome Biogenesis, Ribosomal Protein Stability, and Global Protein Folding.
Qiang M, Khalid F, Phan T, Ludwig C, Scharffetter-Kochanek K, Iben S., Free PMC Article | 10/30/2021 |
| Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD(+) signaling. | Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD(+) signaling.
Okur MN, Fang EF, Fivenson EM, Tiwari V, Croteau DL, Bohr VA., Free PMC Article | 09/4/2021 |
| A role for the Cockayne Syndrome B (CSB)-Elongin ubiquitin ligase complex in signal-dependent RNA polymerase II transcription. | A role for the Cockayne Syndrome B (CSB)-Elongin ubiquitin ligase complex in signal-dependent RNA polymerase II transcription.
Weems JC, Slaughter BD, Unruh JR, Weaver KJ, Miller BD, Delventhal KM, Conaway JW, Conaway RC., Free PMC Article | 08/28/2021 |
| LEO1 is a partner for Cockayne syndrome protein B (CSB) in response to transcription-blocking DNA damage. | LEO1 is a partner for Cockayne syndrome protein B (CSB) in response to transcription-blocking DNA damage.
Tiwari V, Kulikowicz T, Wilson DM 3rd, Bohr VA., Free PMC Article | 07/17/2021 |
| Clinical and Mutation Spectra of Cockayne Syndrome in India. | Clinical and Mutation Spectra of Cockayne Syndrome in India.
Narayanan DL, Tuteja M, McIntyre AD, Hegele RA, Calmels N, Obringer C, Laugel V, Mandal K, Phadke SR. | 07/10/2021 |
| The Winged Helix Domain of CSB Regulates RNAPII Occupancy at Promoter Proximal Pause Sites. | The Winged Helix Domain of CSB Regulates RNAPII Occupancy at Promoter Proximal Pause Sites.
Batenburg NL, Cui S, Walker JR, Schellhorn HE, Zhu XD., Free PMC Article | 06/12/2021 |
| Cockayne Syndrome Group B (CSB): The Regulatory Framework Governing the Multifunctional Protein and Its Plausible Role in Cancer. | Cockayne Syndrome Group B (CSB): The Regulatory Framework Governing the Multifunctional Protein and Its Plausible Role in Cancer.
Spyropoulou Z, Papaspyropoulos A, Lagopati N, Myrianthopoulos V, Georgakilas AG, Fousteri M, Kotsinas A, Gorgoulis VG., Free PMC Article | 05/15/2021 |
| Integrative genomic analysis implicates ERCC6 and its interaction with ERCC8 in susceptibility to breast cancer. | Integrative genomic analysis implicates ERCC6 and its interaction with ERCC8 in susceptibility to breast cancer.
Moslehi R, Tsao HS, Zeinomar N, Stagnar C, Fitzpatrick S, Dzutsev A., Free PMC Article | 04/3/2021 |
| Current and emerging roles of Cockayne syndrome group B (CSB) protein. | Current and emerging roles of Cockayne syndrome group B (CSB) protein.
Tiwari V, Baptiste BA, Okur MN, Bohr VA., Free PMC Article | 03/27/2021 |
| A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair. | A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair.
van den Heuvel D, Spruijt CG, González-Prieto R, Kragten A, Paulsen MT, Zhou D, Wu H, Apelt K, van der Weegen Y, Yang K, Dijk M, Daxinger L, Marteijn JA, Vertegaal ACO, Ljungman M, Vermeulen M, Luijsterburg MS., Free PMC Article | 03/20/2021 |
| USP7-mediated deubiquitination differentially regulates CSB but not UVSSA upon UV radiation-induced DNA damage. | USP7-mediated deubiquitination differentially regulates CSB but not UVSSA upon UV radiation-induced DNA damage.
Zhu Q, Ding N, Wei S, Li P, Wani G, He J, Wani AA., Free PMC Article | 02/2/2021 |
| TCR is initiated by RNAPIIo-bound CSB, which recruits CSA through a newly identified CSA-interaction motif (CIM); once recruited, CSA facilitates the association of UVSSA with stalled RNAPIIo; in addition, UVSSA is the key factor that recruits the TFIIH complex in a manner that is stimulated by CSB and CSA | The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II.
van der Weegen Y, Golan-Berman H, Mevissen TET, Apelt K, González-Prieto R, Goedhart J, Heilbrun EE, Vertegaal ACO, van den Heuvel D, Walter JC, Adar S, Luijsterburg MS., Free PMC Article | 08/13/2020 |