| The mitochondrial redistribution of ENOS is regulated by AKT1 and dimer status. | The mitochondrial redistribution of ENOS is regulated by AKT1 and dimer status.
Sun X, Moreno Caceres S, Yegambaram M, Lu Q, Pokharel MD, Boehme JT, Datar SA, Aggarwal S, Wang T, Fineman JR, Black SM. | 10/25/2024 |
| NaV1.1 contributes to the cell cycle of human mesenchymal stem cells by regulating AKT and CDK2. | NaV1.1 contributes to the cell cycle of human mesenchymal stem cells by regulating AKT and CDK2.
Zakaria MF, Kato H, Sonoda S, Kato K, Uehara N, Kyumoto-Nakamura Y, Sharifa MM, Yu L, Dai L, Yamaza H, Kajioka S, Nishimura F, Yamaza T., Free PMC Article | 10/17/2024 |
| Delivery of AKT1 phospho-forms to human cells reveals differential substrate selectivity. | Delivery of AKT1 phospho-forms to human cells reveals differential substrate selectivity.
Siddika T, Shao R, Heinemann IU, O'Donoghue P. | 10/9/2024 |
| Pleckstrin-2 Mediates the Activation of AKT in Prostate Cancer and Is Repressed by Androgen Receptor. | Pleckstrin-2 Mediates the Activation of AKT in Prostate Cancer and Is Repressed by Androgen Receptor.
Han X, Zhang A, Wang P, Bi H, Ren K, Li E, Yang X, Aydemir I, Tao K, Lin J, Abdulkadir SA, Yang J, Ji P., | 10/7/2024 |
| Aberrant methylation and expression of TNXB promote chondrocyte apoptosis and extracullar matrix degradation in hemophilic arthropathy via AKT signaling. | Aberrant methylation and expression of TNXB promote chondrocyte apoptosis and extracullar matrix degradation in hemophilic arthropathy via AKT signaling.
Chen J, Zeng Q, Wang X, Xu R, Wang W, Huang Y, Sun Q, Yuan W, Wang P, Chen D, Tong P, Jin H., Free PMC Article | 09/26/2024 |
| The roles of stress-induced premature senescence and Akt/FoxO1 signaling in periapical lesions. | The roles of stress-induced premature senescence and Akt/FoxO1 signaling in periapical lesions.
Liu Q, Li S, Tang T, Wu Y. | 09/24/2024 |
| CRLF1 bridges AKT and mTORC2 through SIN1 to inhibit pyroptosis and enhance chemo-resistance in ovarian cancer. | CRLF1 bridges AKT and mTORC2 through SIN1 to inhibit pyroptosis and enhance chemo-resistance in ovarian cancer.
Xiang C, Chen L, Zhu S, Chen Y, Huang H, Yang C, Chi Y, Wang Y, Lei Y, Cai X., Free PMC Article | 09/17/2024 |
| A miRNA-21-Mediated PTEN/Akt/NF-kappaB Axis Promotes Chronic Obstructive Pulmonary Disease Pathogenesis. | A miRNA-21-Mediated PTEN/Akt/NF-κB Axis Promotes Chronic Obstructive Pulmonary Disease Pathogenesis.
Sai X, Qin C, Zhang Z, Yu H, Bian T., Free PMC Article | 08/26/2024 |
| Enhanced lipid biosynthesis in oral squamous cell carcinoma cancer-associated fibroblasts contributes to tumor progression: Role of IL8/AKT/p-ACLY axis. | Enhanced lipid biosynthesis in oral squamous cell carcinoma cancer-associated fibroblasts contributes to tumor progression: Role of IL8/AKT/p-ACLY axis.
Liu P, Wang Y, Li X, Liu Z, Sun Y, Liu H, Shao Z, Jiang E, Zhou X, Shang Z., Free PMC Article | 07/1/2024 |
| FNDC5 inhibits malignant growth of human cervical cancer cells via restraining PI3K/AKT pathway. | FNDC5 inhibits malignant growth of human cervical cancer cells via restraining PI3K/AKT pathway.
Li N, Wang XL, Ge R, Wang Y, Tian XL, Zhu GQ, Zhou B. | 06/14/2024 |
| DNAJC24 acts directly with PCNA and promotes malignant progression of LUAD by activating phosphorylation of AKT. | DNAJC24 acts directly with PCNA and promotes malignant progression of LUAD by activating phosphorylation of AKT.
Liu D, Zuo R, Liu W, He Y, Wang Y, Yue P, Gong W, Cui J, Zhu F, Luo Y, Qi L, Guo Y, Chen L, Li G, Liu Z, Chen P, Guo H. | 06/3/2024 |
| Promoter hypomethylated PDZK1 acts as a tumorigenic gene in glioma by interacting with AKT1. | Promoter hypomethylated PDZK1 acts as a tumorigenic gene in glioma by interacting with AKT1.
Ren X, Deng D, Xiang S, Feng J., Free PMC Article | 05/28/2024 |
| EMX2 inhibits clear cell renal cell carcinoma progress via modulating Akt/FOXO3a pathway. | EMX2 inhibits clear cell renal cell carcinoma progress via modulating Akt/FOXO3a pathway.
Zhou X, Dong S, Zhou Y, He Z, Zhang Z, Liao L, Zou B, Zheng X, Peng K, Duan X. | 04/25/2024 |
| GSG2 promotes thyroid cancer via stabilizing AURKB and activating AKT pathway. | GSG2 promotes thyroid cancer via stabilizing AURKB and activating AKT pathway.
Zhang F, Huang C., Free PMC Article | 04/11/2024 |
| SUMOylation of annexin A6 retards cell migration and tumor growth by suppressing RHOU/AKT1-involved EMT in hepatocellular carcinoma. | SUMOylation of annexin A6 retards cell migration and tumor growth by suppressing RHOU/AKT1-involved EMT in hepatocellular carcinoma.
Yang Y, Huang L, Zhang N, Deng YN, Cao X, Liang Y, Hou H, Luo Y, Yang Y, Li Q, Liang S., Free PMC Article | 04/5/2024 |
| Differential prognostic values of the three AKT isoforms in acute myeloid leukemia. | Differential prognostic values of the three AKT isoforms in acute myeloid leukemia.
Corre E, Soum C, Pfeifer R, Bessière C, Dailhau S, Marbœuf C, Meggetto F, Touriol C, Récher C, Bousquet M, Pyronnet S., Free PMC Article | 04/5/2024 |
| HSPA4 regulated glioma progression via activation of AKT signaling pathway. | HSPA4 regulated glioma progression via activation of AKT signaling pathway.
Yuan X, Sun X, Zhou B, Zhao S, Li Y, Ming H. | 04/4/2024 |
| AKT1 interacts with DHX9 to Mitigate R Loop-Induced Replication Stress in Ovarian Cancer. | AKT1 interacts with DHX9 to Mitigate R Loop-Induced Replication Stress in Ovarian Cancer.
Huang TT, Chiang CY, Nair JR, Wilson KM, Cheng K, Lee JM., Free PMC Article | 03/19/2024 |
| Breast cancer malignancy is governed by regulation of the macroH2A2/TM4SF1 axis, the AKT/NF-kappaB pathway, and elevated MMP13 expression. | Breast cancer malignancy is governed by regulation of the macroH2A2/TM4SF1 axis, the AKT/NF-κB pathway, and elevated MMP13 expression.
Jin Y, Eum DY, Lee C, Park SY, Shim JW, Choi YJ, Choi SH, Kim JG, Heo K, Park SJ. | 03/15/2024 |
| ABHD6 suppresses colorectal cancer progression via AKT signaling pathway. | ABHD6 suppresses colorectal cancer progression via AKT signaling pathway.
Xiong X, Yang C, Jin Y, Zhang R, Wang S, Gan L, Hou S, Bao Y, Zeng Z, Ye Y, Gao Z. | 03/15/2024 |
| All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines. | All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines.
Tian LY, Smit DJ, Popova NV, Horn S, Velasquez LN, Huber S, Jücker M., Free PMC Article | 03/13/2024 |
| KLK10 promotes the progression of KRAS mutant colorectal cancer via PAR1-PDK1-AKT signaling pathway. | KLK10 promotes the progression of KRAS mutant colorectal cancer via PAR1-PDK1-AKT signaling pathway.
Wu K, Wu B, Yan K, Ding Q, Miao Z. | 03/13/2024 |
| STMN1 promotes cell malignancy and bortezomib resistance of multiple myeloma cell lines via PI3K/AKT signaling. | STMN1 promotes cell malignancy and bortezomib resistance of multiple myeloma cell lines via PI3K/AKT signaling.
Wang L, Cao J, Tao J, Liang Y. | 03/8/2024 |
| PAX2 is regulated by estrogen/progesterone through promoter methylation in endometrioid adenocarcinoma and has an important role in carcinogenesis via the AKT/mTOR signaling pathway. | PAX2 is regulated by estrogen/progesterone through promoter methylation in endometrioid adenocarcinoma and has an important role in carcinogenesis via the AKT/mTOR signaling pathway.
Chen H, Li L, Liu H, Qin P, Chen R, Liu S, Xiong H, Li Y, Yang Z, Xie M, Yang H, Jiang Q. | 03/6/2024 |
| Polo-like kinase 4 promotes tumorigenesis and glucose metabolism in glioma by activating AKT1 signaling. | Polo-like kinase 4 promotes tumorigenesis and glucose metabolism in glioma by activating AKT1 signaling.
Wang B, Zhang X, Li ZS, Wei C, Yu RZ, Du XZ, He YJ, Ren Y, Zhen YW, Han L. | 03/5/2024 |