| MiR-23b-3p alleviates Sjogren's syndrome by targeting SOX6 and inhibiting the NF-kappaB signaling. | MiR-23b-3p alleviates Sjögren's syndrome by targeting SOX6 and inhibiting the NF-κB signaling.
Cai Y, Zhang Y, Wang S, Changyong E. | 08/19/2024 |
| Propranolol inhibits EMT and metastasis in breast cancer through miR-499-5p-mediated Sox6. | Propranolol inhibits EMT and metastasis in breast cancer through miR-499-5p-mediated Sox6.
Zheng B, Du P, Zeng Z, Cao P, Ma X, Jiang Y., Free PMC Article | 02/5/2024 |
| Sox6 impairs the adipogenic commitment of mesenchymal stem cells by targeting lysyl oxidase and preadipocyte factor 1. | Sox6 impairs the adipogenic commitment of mesenchymal stem cells by targeting lysyl oxidase and preadipocyte factor 1.
Du SY, Hu L, Zhou BH, Zhang Z, Li MC, Chang D, Xu CJ, Dou X. | 11/2/2023 |
| KNOCKDOWN OF CIRC_0001379 ATTENUATES HYPOXIA/REOXYGENATION-INDUCED CARDIOMYOCYTE APOPTOSIS AND INFLAMMATORY RESPONSE BY MIR-98-5P/SOX6 AXIS. | KNOCKDOWN OF CIRC_0001379 ATTENUATES HYPOXIA/REOXYGENATION-INDUCED CARDIOMYOCYTE APOPTOSIS AND INFLAMMATORY RESPONSE BY MIR-98-5P/SOX6 AXIS.
Wang K, Wang H, Zhang Q, Liu F. | 09/18/2023 |
| Sirt6 reprograms myofibers to oxidative type through CREB-dependent Sox6 suppression. | Sirt6 reprograms myofibers to oxidative type through CREB-dependent Sox6 suppression.
Song MY, Han CY, Moon YJ, Lee JH, Bae EJ, Park BH., Free PMC Article | 04/23/2022 |
| The Transcription Factor Sox6 Controls Renin Expression during Renal Artery Stenosis. | The Transcription Factor Sox6 Controls Renin Expression during Renal Artery Stenosis.
Saleem M, Saavedra-Sánchez L, Barturen-Larrea P, Gomez JA., Free PMC Article | 04/16/2022 |
| Suppression of MALAT1 alleviates neurocyte apoptosis and reactive oxygen species production through the miR-499-5p/SOX6 axis in subarachnoid hemorrhage. | Suppression of MALAT1 alleviates neurocyte apoptosis and reactive oxygen species production through the miR-499-5p/SOX6 axis in subarachnoid hemorrhage.
Zhou X, Zheng B, Pang L, Che Y, Qi X. | 03/26/2022 |
| LncRNA Dlx6os1 Accelerates Diabetic Nephropathy Progression by Epigenetically Repressing SOX6 via Recruiting EZH2. | LncRNA Dlx6os1 Accelerates Diabetic Nephropathy Progression by Epigenetically Repressing SOX6 via Recruiting EZH2.
Chen YX, Zhu SY, Huang C, Xu CY, Fang XD, Tu WP. | 03/19/2022 |
| Sox6 expression distinguishes dorsally and ventrally biased dopamine neurons in the substantia nigra with distinctive properties and embryonic origins. | Sox6 expression distinguishes dorsally and ventrally biased dopamine neurons in the substantia nigra with distinctive properties and embryonic origins.
Pereira Luppi M, Azcorra M, Caronia-Brown G, Poulin JF, Gaertner Z, Gatica S, Moreno-Ramos OA, Nouri N, Dubois M, Ma YC, Ramakrishnan C, Fenno L, Kim YS, Deisseroth K, Cicchetti F, Dombeck DA, Awatramani R., Free PMC Article | 02/19/2022 |
| Postnatal Sox6 Regulates Synaptic Function of Cortical Parvalbumin-Expressing Neurons. | Postnatal Sox6 Regulates Synaptic Function of Cortical Parvalbumin-Expressing Neurons.
Munguba H, Chattopadhyaya B, Nilsson S, Carriço JN, Memic F, Oberst P, Batista-Brito R, Muñoz-Manchado AB, Wegner M, Fishell G, Di Cristo G, Hjerling-Leffler J., Free PMC Article | 11/27/2021 |
| MiR-17-3p inhibits osteoblast differentiation by downregulating Sox6 expression. | MiR-17-3p inhibits osteoblast differentiation by downregulating Sox6 expression.
Chen N, Wu D, Li H, Liu Y, Yang H., Free PMC Article | 11/27/2021 |
| Knockdown of lncRNA XIST inhibited apoptosis and inflammation in renal fibrosis via microRNA-19b-mediated downregulation of SOX6. | Knockdown of lncRNA XIST inhibited apoptosis and inflammation in renal fibrosis via microRNA-19b-mediated downregulation of SOX6.
Xia WP, Chen X, Ru F, He Y, Liu PH, Gan Y, Zhang B, Li Y, Dai GY, Jiang ZX, Chen Z. | 11/6/2021 |
| Inhibition of long non-coding RNA TSIX accelerates tibia fraction healing via binding and positively regulating the SOX6 expression. | Inhibition of long non-coding RNA TSIX accelerates tibia fraction healing via binding and positively regulating the SOX6 expression.
Xu WW, Xu Y, Ji F, Ji Y, Wang QG. | 04/3/2021 |
| Long non-coding RNA CHRF modulates the progression of cerebral ischemia/reperfusion injury via miR-126/SOX6 signaling pathway. | Long non-coding RNA CHRF modulates the progression of cerebral ischemia/reperfusion injury via miR-126/SOX6 signaling pathway.
Gai HY, Wu C, Zhang Y, Wang D. | 06/20/2020 |
| Sox6 contributes in the regulation of renin expression in the kidney. | Sox6 as a new modulator of renin expression in the kidney.
Saleem M, Hodgkinson CP, Xiao L, Gimenez-Bastida JA, Rasmussen ML, Foss J, Payne AJ, Mirotsou M, Gama V, Dzau VJ, Gomez JA., Free PMC Article | 05/16/2020 |
| through alternative splicing, LncRNA C130071C03Riken variants Riken-201 (Riken-201) and Riken-203 (Riken-203) identify the functional role of Rik-201 and Rik-203 in facilitating neural differentiation and further brain development, and elucidate the underlying miRNAs-Sox6-associated molecular mechanisms | LncRNA Riken-201 and Riken-203 modulates neural development by regulating the Sox6 through sequestering miRNAs.
Zhang L, Xue Z, Yan J, Wang J, Liu Q, Jiang H., Free PMC Article | 06/22/2019 |
| the novel role of Tgfb2, Fbxl18, and Tle3 in formation of Sox5, Sox6, and Sox9 dependent tissues. | An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos.
Lee WJ, Chatterjee S, Yap SP, Lim SL, Xing X, Kraus P, Sun W, Hu X, Sivakamasundari V, Chan HY, Kolatkar PR, Prabhakar S, Lufkin T., Free PMC Article | 03/17/2018 |
| These data demonstrate functional cooperation between Sox6 and Nfix in regulating MyHC-I expression during prenatal muscle development. | Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle.
Taglietti V, Maroli G, Cermenati S, Monteverde S, Ferrante A, Rossi G, Cossu G, Beltrame M, Messina G., Free PMC Article | 11/25/2017 |
| Sox6 plays an important role in suppressing cell proliferation and modulating fetal gene expression during postnatal heart development. | Transcriptome Dynamics and Potential Roles of Sox6 in the Postnatal Heart.
An CI, Ichihashi Y, Peng J, Sinha NR, Hagiwara N., Free PMC Article | 06/24/2017 |
| findings suggest that Sox6 contributes to cell survival by suppressing BMP-4 transcription during neuronal differentiation | Sox6 suppression induces RA-dependent apoptosis mediated by BMP-4 expression during neuronal differentiation in P19 cells.
Hamada-Kanazawa M, Ogawa D, Takano M, Miyake M., Free PMC Article | 11/5/2016 |
| Study revealed that Sox5 and Sox6 prevent oligodendroglial differentiation, thus ensuring that the progenitor cells first reach their proper destination and only then lose their migratory capacity | Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain.
Baroti T, Zimmermann Y, Schillinger A, Liu L, Lommes P, Wegner M, Stolt CC. | 10/22/2016 |
| This study demonstrated that Sox13 functionally complements the related Sox5 and Sox6 as important developmental modulators in mouse spinal cord oligodendrocytes. | Sox13 functionally complements the related Sox5 and Sox6 as important developmental modulators in mouse spinal cord oligodendrocytes.
Baroti T, Schillinger A, Wegner M, Stolt CC. | 08/6/2016 |
| We found that miR-21 acts as a bidirectional switch in the formation of IPCs by regulating the expression of target and downstream genes (SOX6, RPBJ and HES1). | Role of microRNA-21 in the formation of insulin-producing cells from pancreatic progenitor cells.
Bai C, Li X, Gao Y, Wang K, Fan Y, Zhang S, Ma Y, Guan W. | 06/28/2016 |
| Loss of Trbp function results in upregulation of Sox6. | Trbp regulates heart function through microRNA-mediated Sox6 repression.
Ding J, Chen J, Wang Y, Kataoka M, Ma L, Zhou P, Hu X, Lin Z, Nie M, Deng ZL, Pu WT, Wang DZ., Free PMC Article | 09/12/2015 |
| After cell-cycle exit, Sox6 selectively localizes to substantia nigra pars compacta neurons, while Otx2 and Nolz1 are expressed in a subset of ventral tegmental area neurons. | Sox6 and Otx2 control the specification of substantia nigra and ventral tegmental area dopamine neurons.
Panman L, Papathanou M, Laguna A, Oosterveen T, Volakakis N, Acampora D, Kurtsdotter I, Yoshitake T, Kehr J, Joodmardi E, Muhr J, Simeone A, Ericson J, Perlmann T. | 05/30/2015 |