| Baf155 controls hematopoietic differentiation and regeneration through chromatin priming. | Baf155 controls hematopoietic differentiation and regeneration through chromatin priming.
Wu J, Fan C, Kabir AU, Krchma K, Kim M, Kwon Y, Xing X, Wang T, Choi K., Free PMC Article | 10/8/2024 |
| The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds. | The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds.
Ramachandran J, Chen W, Lex RK, Windsor KE, Lee H, Wang T, Zhou W, Ji H, Vokes SA. | 11/10/2023 |
| Baf155 regulates skeletal muscle metabolism via HIF-1a signaling. | Baf155 regulates skeletal muscle metabolism via HIF-1a signaling.
Kang JS, Kim D, Rhee J, Seo JY, Park I, Kim JH, Lee D, Lee W, Kim YL, Yoo K, Bae S, Chung J, Seong RH, Kong YY., Free PMC Article | 08/4/2023 |
| Role of the Pbrm1 subunit and the PBAF complex in Schwann cell development. | Role of the Pbrm1 subunit and the PBAF complex in Schwann cell development.
Polanetzki V, Fröb F, Baroti T, Schimmel M, Tamm ER, Wegner M., Free PMC Article | 03/19/2022 |
| Requisite Chromatin Remodeling for Myeloid and Erythroid Lineage Differentiation from Erythromyeloid Progenitors. | Requisite Chromatin Remodeling for Myeloid and Erythroid Lineage Differentiation from Erythromyeloid Progenitors.
Wu J, Krchma K, Lee HJ, Prabhakar S, Wang X, Zhao H, Xing X, Seong RH, Fremont DH, Artyomov MN, Wang T, Choi K., Free PMC Article | 11/13/2021 |
| Chromatin Regulator SRG3 Overexpression Protects against LPS/D-GalN-Induced Sepsis by Increasing IL10-Producing Macrophages and Decreasing IFNgamma-Producing NK Cells in the Liver. | Chromatin Regulator SRG3 Overexpression Protects against LPS/D-GalN-Induced Sepsis by Increasing IL10-Producing Macrophages and Decreasing IFNγ-Producing NK Cells in the Liver.
Lee SW, Park HJ, Jeon J, Park YH, Kim TC, Jeon SH, Seong RH, Van Kaer L, Hong S., Free PMC Article | 04/24/2021 |
| Forkhead Box O3a requires BAF57, a subunit of chromatin remodeler SWI/SNF complex for induction of p53 up-regulated modulator of apoptosis (Puma) in a model of Parkinson's disease. | Forkhead Box O3a requires BAF57, a subunit of chromatin remodeler SWI/SNF complex for induction of p53 up-regulated modulator of apoptosis (Puma) in a model of Parkinson's disease.
Sanphui P, Kumar Das A, Biswas SC. | 02/6/2021 |
| the regulation of BAF155 by RBM15 depends on the activity of the mRNA methylation complex core catalytic subunit METTL3. | RBM15 Modulates the Function of Chromatin Remodeling Factor BAF155 Through RNA Methylation in Developing Cortex.
Xie Y, Castro-Hernández R, Sokpor G, Pham L, Narayanan R, Rosenbusch J, Staiger JF, Tuoc T. | 03/14/2020 |
| Conditional deletion of BAF155 causes impaired proliferation of olfactory neurons and defective axonogenesis in the developing olfactory epithelium. | mSWI/SNF (BAF) Complexes Are Indispensable for the Neurogenesis and Development of Embryonic Olfactory Epithelium.
Bachmann C, Nguyen H, Rosenbusch J, Pham L, Rabe T, Patwa M, Sokpor G, Seong RH, Ashery-Padan R, Mansouri A, Stoykova A, Staiger JF, Tuoc T., Free PMC Article | 05/13/2017 |
| BAF155 mediates the interaction between BAF complexes and H3K27demethylases, controlling the global level of H3K27me2/3 and ultimately the gene expression program in cortical development. | Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.
Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T. | 12/17/2016 |
| the role of BAF155 in late pre-implantation stages of mouse embryos | The BAF chromatin remodelling complex is an epigenetic regulator of lineage specification in the early mouse embryo.
Panamarova M, Cox A, Wicher KB, Butler R, Bulgakova N, Jeon S, Rosen B, Seong RH, Skarnes W, Crabtree G, Zernicka-Goetz M., Free PMC Article | 09/10/2016 |
| Specific inactivation of Srg3 a core subunit of the remodeling complex, in developing limb buds hampered the transcriptional upregulation of Shh/Gli target genes, including the Shh receptor Ptch1 and its downstream effector Gli1 in the posterior limb bud | Anteroposterior Limb Skeletal Patterning Requires the Bifunctional Action of SWI/SNF Chromatin Remodeling Complex in Hedgehog Pathway.
Jeon S, Seong RH., Free PMC Article | 08/6/2016 |
| the increased frequency of Treg cells in the spinal cord of beta-actin-SRG3 Tg mice might induce the suppression of and accelerate the recovery from EAE symptoms. | Ubiquitous Over-Expression of Chromatin Remodeling Factor SRG3 Ameliorates the T Cell-Mediated Exacerbation of EAE by Modulating the Phenotypes of both Dendritic Cells and Macrophages.
Lee SW, Park HJ, Jeon SH, Lee C, Seong RH, Park SH, Hong S., Free PMC Article | 04/16/2016 |
| Deletion of either Brg1 in the subependymal zone (SEZ) causes the progeny of adult neural stem cells to convert to the ependymal lineage within the SEZ while migrating neuroblasts convert to different glial lineages en route to or in the olfactory bulb. | The BAF complex interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network.
Ninkovic J, Steiner-Mezzadri A, Jawerka M, Akinci U, Masserdotti G, Petricca S, Fischer J, von Holst A, Beckers J, Lie CD, Petrik D, Miller E, Tang J, Wu J, Lefebvre V, Demmers J, Eisch A, Metzger D, Crabtree G, Irmler M, Poot R, Götz M., Free PMC Article | 01/3/2015 |
| Characterization of a missense mutation allele of the Smarcc1 gene (Smarcc1msp3 or Baf155msp3); lends new insight into the functions of the BAF chromatin remodeling complex during the critical stage of neural tube closure | A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice.
Harmacek L, Watkins-Chow DE, Chen J, Jones KL, Pavan WJ, Salbaum JM, Niswander L., Free PMC Article | 12/6/2014 |
| we identify BAF155 as a substrate for arginine methyltransferase CARM1. | CARM1 methylates chromatin remodeling factor BAF155 to enhance tumor progression and metastasis.
Wang L, Zhao Z, Meyer MB, Saha S, Yu M, Guo A, Wisinski KB, Huang W, Cai W, Pike JW, Yuan M, Ahlquist P, Xu W., Free PMC Article | 03/29/2014 |
| Wwp2 acts as a ubiquitin ligase of SRG3. | Wwp2 targets SRG3, a scaffold protein of the SWI/SNF-like BAF complex, for ubiquitination and degradation.
Luo X, Wang B, Tang F, Zhang J, Zhao Y, Li H, Jin Y. | 03/22/2014 |
| Liver progenitor cells have intrinsic, cell proliferation-independent characteristics resulting in an increased reprogramming capacity compared to differentiated liver cells which requires the BAF complex. | Increased reprogramming capacity of mouse liver progenitor cells, compared with differentiated liver cells, requires the BAF complex.
Kleger A, Mahaddalkar PU, Katz SF, Lechel A, Joo JY, Loya K, Lin Q, Hartmann D, Liebau S, Kraus JM, Cantz T, Kestler HA, Zaehres H, Schöler H, Rudolph KL. | 06/2/2012 |
| CHFR interacts with BRG1, SNF5, and BAF60a of the SWI/SNF-like BAF complex and ubiquitinates them to target for degradation through a proteasome-mediated pathway; SRG3 stabilizes these components by blocking their interaction with CHFR. | SRG3/mBAF155 stabilizes the SWI/SNF-like BAF complex by blocking CHFR mediated ubiquitination and degradation of its major components.
Jung I, Sohn DH, Choi J, Kim JM, Jeon S, Seol JH, Seong RH. | 04/14/2012 |
| Our results establish a novel function of Srg3 in tumor suppression | Srg3, a mouse homolog of BAF155, is a novel p53 target and acts as a tumor suppressor by modulating p21(WAF1/CIP1) expression.
Ahn J, Ko M, Lee C, Kim J, Yoon H, Seong RH. | 03/19/2011 |
| report that members of the PBAF chromatin remodeling complex, including Smarca4/Brg1, Smarcb1/Baf47, Smarcc1/Baf155, and Smarce1/Baf57, are required for the repression of Nanog and other self-renewal gene expression upon mouse ESC (mESC) differentiation. | Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells.
Schaniel C, Ang YS, Ratnakumar K, Cormier C, James T, Bernstein E, Lemischka IR, Paddison PJ., Free PMC Article | 03/29/2010 |
| the SWI/SNF complex plays a critical role during T cell activation and subsequent immune responses | The SWI/SNF chromatin-remodeling complex modulates peripheral T cell activation and proliferation by controlling AP-1 expression.
Jeong SM, Lee C, Lee SK, Kim J, Seong RH., Free PMC Article | 03/1/2010 |
| SRG3 is essential for extra-embryonic vascular development. | SRG3, a core component of mouse SWI/SNF complex, is essential for extra-embryonic vascular development.
Han D, Jeon S, Sohn DH, Lee C, Ahn S, Kim WK, Chung H, Seong RH. | 01/21/2010 |
| SRG3 expression in thymus is repressed by nitric oxide in an anti-apoptotic process | Nitric oxide inhibits glucocorticoid-induced apoptosis of thymocytes by repressing the SRG3 expression.
Jeong SM, Lee KY, Shin D, Chung H, Jeon SH, Seong RH. | 01/21/2010 |
| results suggest that diverse interactions between Sp1/Sp3 and Ets factors are crucial for the SRG3 gene expression | Expression of SRG3, a core component of mouse SWI/SNF chromatin-remodeling complex, is regulated by cooperative interactions between Sp1/Sp3 and Ets transcription factors.
Ahn J, Ko M, Lee K, Oh J, Jeon SH, Seong RH. | 01/21/2010 |