| LPCAT1 Facilitates Keratinocyte Hyperproliferation and Skin Inflammation in Psoriasis by Regulating GLUT3. | LPCAT1 Facilitates Keratinocyte Hyperproliferation and Skin Inflammation in Psoriasis by Regulating GLUT3.
Huang Y, Wang Y, Zhen Y, Liu W, Wang Y, Wang R, Wang N, Huang S, Yan J, Sun Q. | 07/11/2024 |
| GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing. | GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing.
Yu DM, Zhao J, Lee EE, Kim D, Mahapatra R, Rose EK, Zhou Z, Hosler C, El Kurdi A, Choe JY, Abel ED, Hoxhaj G, Westover KD, Cho RJ, Cheng JB, Wang RC., Free PMC Article | 11/6/2023 |
| Recurrent moderate hypoglycemia accelerates the progression of Alzheimer's disease through impairment of the TRPC6/GLUT3 pathway. | Recurrent moderate hypoglycemia accelerates the progression of Alzheimer's disease through impairment of the TRPC6/GLUT3 pathway.
He C, Li Q, Cui Y, Gao P, Shu W, Zhou Q, Wang L, Li L, Lu Z, Zhao Y, Ma H, Chen X, Jia H, Zheng H, Yang G, Liu D, Tepel M, Zhu Z., Free PMC Article | 04/23/2022 |
| The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming. | The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming.
Hochrein SM, Wu H, Eckstein M, Arrigoni L, Herman JS, Schumacher F, Gerecke C, Rosenfeldt M, Grün D, Kleuser B, Gasteiger G, Kastenmüller W, Ghesquière B, Van den Bossche J, Abel ED, Vaeth M., Free PMC Article | 04/23/2022 |
| Developing Brain Glucose Transporters, Serotonin, Serotonin Transporter, and Oxytocin Receptor Expression in Response to Early-Life Hypocaloric and Hypercaloric Dietary, and Air Pollutant Exposures. | Developing Brain Glucose Transporters, Serotonin, Serotonin Transporter, and Oxytocin Receptor Expression in Response to Early-Life Hypocaloric and Hypercaloric Dietary, and Air Pollutant Exposures.
Ye X, Shin BC, Baldauf C, Ganguly A, Ghosh S, Devaskar SU., Free PMC Article | 01/22/2022 |
| Analysis of glucose metabolism by (18)F-FDG-PET imaging and glucose transporter expression in a mouse model of intracerebral hemorrhage. | Analysis of glucose metabolism by (18)F-FDG-PET imaging and glucose transporter expression in a mouse model of intracerebral hemorrhage.
Han X, Ren H, Nandi A, Fan X, Koehler RC., Free PMC Article | 11/6/2021 |
| Adult glut3 homozygous null mice survive to demonstrate neural excitability and altered neurobehavioral responses reminiscent of neurodevelopmental disorders. | Adult glut3 homozygous null mice survive to demonstrate neural excitability and altered neurobehavioral responses reminiscent of neurodevelopmental disorders.
Shin BC, Cepeda C, Eghbali M, Byun SY, Levine MS, Devaskar SU., Free PMC Article | 09/18/2021 |
| High NOV/CCN3 expression during high-fat diet pregnancy in mice affects GLUT3 expression and the mTOR pathway. | High NOV/CCN3 expression during high-fat diet pregnancy in mice affects GLUT3 expression and the mTOR pathway.
Wang H, Huang B, Hou A, Xue L, Wang B, Chen J, Li M, Zhang JV. | 05/29/2021 |
| CD205(+) polymorphonuclear myeloid-derived suppressor cells suppress antitumor immunity by overexpressing GLUT3. | CD205(+) polymorphonuclear myeloid-derived suppressor cells suppress antitumor immunity by overexpressing GLUT3.
Fu C, Fu Z, Jiang C, Xia C, Zhang Y, Gu X, Zheng K, Zhou D, Tang S, Lyu S, Ma S., Free PMC Article | 03/20/2021 |
| Sevoflurane Induces Learning and Memory Impairment in Young Mice Through a Reduction in Neuronal Glucose Transporter 3. | Sevoflurane Induces Learning and Memory Impairment in Young Mice Through a Reduction in Neuronal Glucose Transporter 3.
Zhu J, Zhang Z, Jia J, Wang L, Yang Q, Wang Y, Chen C., Free PMC Article | 01/23/2021 |
| Regular Exercise Enhances Cognitive Function and Intracephalic GLUT Expression in Alzheimer's Disease Model Mice. | Regular Exercise Enhances Cognitive Function and Intracephalic GLUT Expression in Alzheimer's Disease Model Mice.
Pang R, Wang X, Pei F, Zhang W, Shen J, Gao X, Chang C. | 11/21/2020 |
| GLUT3 is essential for breast cancer cell survival in the brain. | Glucose Transporter 3 is Essential for the Survival of Breast Cancer Cells in the Brain.
Kuo MH, Chang WW, Yeh BW, Chu YS, Lee YC, Lee HT., Free PMC Article | 08/1/2020 |
| Diabetes-induced hyperglycemia reduces the capability of ovarian follicle cells by down-regulating Glut3 expression. | Changes in Expression of Follicular Glucose Transporters May Be Involved in Ovarian Function Impairment during Diabetic Hyperglycemia.
Xu B, Hu Y, Luo YT, Xu H, Qi SH, Zhang YY, Zhao D, Yuan DZ. | 06/27/2020 |
| Lack of Glut3 during early postnatal life, results in a reduction in dendritic spines and brain size, along with a shortened lifespan. | Neural Deletion of Glucose Transporter Isoform 3 Creates Distinct Postnatal and Adult Neurobehavioral Phenotypes.
Shin BC, Cepeda C, Estrada-Sánchez AM, Levine MS, Hodaei L, Dai Y, Jung J, Ganguly A, Clark P, Devaskar SU., Free PMC Article | 10/12/2019 |
| 1) that decrease of GLUT3 is associated with the reduction of protein O-GlcNAcylation in Alzheimer's disease (AD)brain, 2) that GLUT3 level is negatively correlated with calpain I activation in human brain, 3) that calpain I proteolyzes GLUT3 at the N-terminus in vitro, and 4) that activation of calpain I is negatively correlated with protein O-GlcNAcylation in AD brain. | Calpain I Activation Causes GLUT3 Proteolysis and Downregulation of O-GlcNAcylation in Alzheimer's Disease Brain.
Gu J, Jin N, Ma D, Chu D, Iqbal K, Gong CX, Liu F. | 06/1/2019 |
| Study found no differences in mRNA or protein levels of neuronal monocarboxylate transporters (MCTs). Functional analyses revealed that neuronal MCT2 had high catalytic efficiency in Huntington's disease (HD) cells. Ascorbic acid did not stimulate lactate uptake in HD cells; and was unable to inhibit glucose transport in HD cells because they exhibit decreased expression of the neuronal glucose transporter GLUT3. | Altered lactate metabolism in Huntington's disease is dependent on GLUT3 expression.
Solís-Maldonado M, Miró MP, Acuña AI, Covarrubias-Pinto A, Loaiza A, Mayorga G, Beltrán FA, Cepeda C, Levine MS, Concha II, Bátiz LF, Carrasco MA, Castro MA., Free PMC Article | 12/22/2018 |
| Neonatal hypothyroridism downregulates the expressions of GLUT3 and GLUT8 in the testis of perpubertal mice. | Neonatal hypothyroidism affects testicular glucose homeostasis through increased oxidative stress in prepubertal mice: effects on GLUT3, GLUT8 and Cx43.
Sarkar D, Singh SK. | 02/3/2018 |
| GLUT3-mediated glucose utilization and glycogenolysis in platelets promotes alpha-granule release, platelet activation, and postactivation functions. | Glucose Transporter 3 Potentiates Degranulation and Is Required for Platelet Activation.
Fidler TP, Middleton EA, Rowley JW, Boudreau LH, Campbell RA, Souvenir R, Funari T, Tessandier N, Boilard E, Weyrich AS, Abel ED., Free PMC Article | 09/9/2017 |
| Morphological changes and GLUT1, GLUT3, and GLUT4 expression were evaluated in placentas by immunohistochemical and image analysis and correlated with iAs and arsenical species concentration, which were quantified by atomic absorption spectroscopy | Prenatal Exposure to Sodium Arsenite Alters Placental Glucose 1, 3, and 4 Transporters in Balb/c Mice.
Gutiérrez-Torres DS, González-Horta C, Del Razo LM, Infante-Ramírez R, Ramos-Martínez E, Levario-Carrillo M, Sánchez-Ramírez B., Free PMC Article | 05/21/2016 |
| Results define Glut3 to be a rab11-dependent trafficking cargo and suggest that impaired Glut3 trafficking arising from rab11 dysfunction underlies the glucose hypometabolism observed in Huntington's disease | Glucose transporter 3 is a rab11-dependent trafficking cargo and its transport to the cell surface is reduced in neurons of CAG140 Huntington's disease mice.
McClory H, Williams D, Sapp E, Gatune LW, Wang P, DiFiglia M, Li X., Free PMC Article | 10/31/2015 |
| Glut3 is a downstream target of mTORC1, and it is critical for oncogenic mTORC1-mediated aerobic glycolysis and tumorigenesis. | NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth.
Zha X, Hu Z, Ji S, Jin F, Jiang K, Li C, Zhao P, Tu Z, Chen X, Di L, Zhou H, Zhang H. | 04/11/2015 |
| GLUT3 levels in the brains of scrapie-infected animals was significantly downregulated. | Significant reduction of the GLUT3 level, but not GLUT1 level, was observed in the brain tissues of several scrapie experimental animals and scrapie-infected cell lines.
Yan YE, Zhang J, Wang K, Xu Y, Ren K, Zhang BY, Shi M, Chen C, Shi Q, Tian C, Zhao G, Dong XP. | 11/22/2014 |
| Placental endoplasmic reticulum stress by administration of Tun causes downregulation of Slc2a1(GLUT1) and upregulation of Slc2a3(GLUT3) mRNA expression. | Prolonged endoplasmic reticulum stress alters placental morphology and causes low birth weight.
Kawakami T, Yoshimi M, Kadota Y, Inoue M, Sato M, Suzuki S. | 04/26/2014 |
| knock-down of glucose transporter 3 in embryonic stem cells impaired the beating function of ESC-derived cardiomyocytes, suggesting its potential role in mediating stem cell differentiation | Reprogramming- and pluripotency-associated membrane proteins in mouse stem cells revealed by label-free quantitative proteomics.
Hao J, Li W, Dan J, Ye X, Wang F, Zeng X, Wang L, Wang H, Cheng Y, Liu L, Shui W. | 01/11/2014 |
| Data suggest that co-activation of CREST (calcium-responsive transactivator) and CBP (CREB-binding protein) enhances signaling between p-Creb/AP-1 and p-HIF-1/HRE resulting in up-regulation of Glut3 gene; here, stimulus was cell hypoxia. | Hypoxic adaptation engages the CBP/CREST-induced coactivator complex of Creb-HIF-1α in transactivating murine neuroblastic glucose transporter.
Thamotharan S, Raychaudhuri N, Tomi M, Shin BC, Devaskar SU., Free PMC Article | 05/11/2013 |