| EPOXID HYDROLASE SINGLE GENE POLYMORPHISM (RS1051740) AND SEVERITY OF CHRONIC OBSTRUCTIVE DISEASE. | EPOXID HYDROLASE SINGLE GENE POLYMORPHISM (RS1051740) AND SEVERITY OF CHRONIC OBSTRUCTIVE DISEASE.
Antonova I, Gridnyev O, Galchinskaya V. | 01/14/2023 |
| Oxidative stress-related genes (EPHX1 and MnSOD) polymorphism and risk of pre-eclampsia: a meta-analysis. | Oxidative stress-related genes (EPHX1 and MnSOD) polymorphism and risk of pre-eclampsia: a meta-analysis.
Zhao G, Liu J, Meng T. | 11/26/2022 |
| Genetic polymorphisms in the mEH gene in relation to tobacco smoking: role in lung cancer susceptibility and survival in north Indian patients with lung cancer undergoing platinum-based chemotherapy. | Genetic polymorphisms in the mEH gene in relation to tobacco smoking: role in lung cancer susceptibility and survival in north Indian patients with lung cancer undergoing platinum-based chemotherapy.
Walia HK, Singh N, Sharma S. | 05/21/2022 |
| EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence. | EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence.
Gautheron J, Morisseau C, Chung WK, Zammouri J, Auclair M, Baujat G, Capel E, Moulin C, Wang Y, Yang J, Hammock BD, Cerame B, Phan F, Fève B, Vigouroux C, Andreelli F, Jeru I., Free PMC Article | 09/25/2021 |
| ABCB1 c.3435C > T and EPHX1 c.416A > G polymorphisms influence plasma carbamazepine concentration, metabolism, and pharmacoresistance in epileptic patients. | ABCB1 c.3435C > T and EPHX1 c.416A > G polymorphisms influence plasma carbamazepine concentration, metabolism, and pharmacoresistance in epileptic patients.
Zhang ML, Chen XL, Bai ZF, Zhao X, Li WX, Wang XY, Zhang H, Chen XF, Zhang SQ, Tang JF, Xiao XH, Zhao YL. | 09/18/2021 |
| Effects of EPHX1 rs2260863 polymorphisms on warfarin maintenance dose in very elderly, frail Han-Chinese population. | Effects of EPHX1 rs2260863 polymorphisms on warfarin maintenance dose in very elderly, frail Han-Chinese population.
Lin X, Chen H, Ni L, Yu Y, Luo Z, Liao L. | 06/26/2021 |
| Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues. | Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues.
Morisseau C, Kodani SD, Kamita SG, Yang J, Lee KSS, Hammock BD., Free PMC Article | 06/19/2021 |
| Peroxisome proliferator-activated receptor a (PPARa)-cytochrome P450 epoxygenases-soluble epoxide hydrolase axis in ER + PR + HER2- breast cancer. | Peroxisome proliferator-activated receptor ɑ (PPARɑ)-cytochrome P450 epoxygenases-soluble epoxide hydrolase axis in ER + PR + HER2- breast cancer.
Tauber Z, Koleckova M, Cizkova K. | 06/5/2021 |
| Proteomic Analysis Reveals that EPHX1 Contributes to 5-Fluorouracil Resistance in a Human Hepatocellular Carcinoma Cell Line. | Proteomic Analysis Reveals that EPHX1 Contributes to 5-Fluorouracil Resistance in a Human Hepatocellular Carcinoma Cell Line.
Sun R, Dong C, Li R, Chu H, Liu J, Hao D, Zhang L, Zhao B, Wang L, Zhang Y. | 06/5/2021 |
| Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury. | Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury.
Jamieson KL, Darwesh AM, Sosnowski DK, Zhang H, Shah S, Zhabyeyev P, Yang J, Hammock BD, Edin ML, Zeldin DC, Oudit GY, Kassiri Z, Seubert JM., Free PMC Article | 04/17/2021 |
| The Multifaceted Role of Epoxide Hydrolases in Human Health and Disease. | The Multifaceted Role of Epoxide Hydrolases in Human Health and Disease.
Gautheron J, Jéru I., Free PMC Article | 04/3/2021 |
| LINC00205 modulates the expression of EPHX1 through the inhibition of miR-184 in hepatocellular carcinoma as a ceRNA. | LINC00205 modulates the expression of EPHX1 through the inhibition of miR-184 in hepatocellular carcinoma as a ceRNA.
Long X, Li Q, Zhi LJ, Li JM, Wang ZY. | 12/19/2020 |
| results suggest that sEH participates in the inflammatory changes in human gestational tissues in pregnancies complicated by acute Chorioamnionitis . | Increased Soluble Epoxide Hydrolase in Human Gestational Tissues from Pregnancies Complicated by Acute Chorioamnionitis.
Hung TH, Chen SF, Wu CH, Kao CC, Wu CP., Free PMC Article | 06/13/2020 |
| AURKA polymorphisms are susceptible factors for oral cancer | Association between EPHX1 polymorphism rs1051740 and the risk of ovarian cancer: a meta-analysis.
Jin Y. | 11/23/2019 |
| The different antioxidant capacity of COPD patients with different EPHX1 genotypes may be related to the polymorphism of EPHX1 gene affecting the activity of microsomal epoxidase, but not to the level of EPHX1 mRNA and protein expression. | [Study on the relationship between EPHX1 gene polymorphism and antioxidant capacity in patients with chronic obstructive pulmonary disease].
Luo Y, Dai LM, Jia M, Zhao ZH, Hu CM, Qi WY, Zhang JQ. | 10/26/2019 |
| EPHX1 genetic polymorphism plays an important role in acute myeloid leukemia genetic susceptibility in early age by modulating the carcinogenic effects of epoxide exposures in the bone marrow. | EPHX1 rs1051740 T>C (Tyr113His) is strongly associated with acute myeloid leukemia and KMT2A rearrangements in early age.
Brisson GD, de Almeida Lopes B, Andrade FG, Dos Santos Bueno FV, Sardou-Cezar I, de Aguiar Gonçalves BA, Terra-Granado E, Paraguassú-Braga FH, Pombo-de-Oliveira MS. | 09/7/2019 |
| A possible modifying effect of Polycyclic aromatic hydrocarbons exposure on genetic polymorphisms of EPHX1 was found in susceptibility to congenital heart diseases. | The effect on congenital heart diseases of maternal EPHX1 polymorphisms modified by polycyclic aromatic hydrocarbons exposure.
Tao J, Li N, Liu Z, Deng Y, Li X, Chen M, Yu J, Zhu J, Yu P, Wang Y., Free PMC Article | 08/3/2019 |
| High EPHX1 expression is associated with chemoresistance of acute myeloid leukemia. | Emerging role of EPHX1 in chemoresistance of acute myeloid leukemia by regurlating drug-metabolizing enzymes and apoptotic signaling.
Cheng H, Huang C, Tang G, Qiu H, Gao L, Zhang W, Wang J, Yang J, Chen L. | 07/6/2019 |
| Methylation levels in EPHX1 promoter associated with carbamazepine-resistant epilepsy significantly | Different EPHX1 methylation levels in promoter area between carbamazepine-resistant epilepsy group and carbamazepine-sensitive epilepsy group in Chinese population.
Lv Y, Zheng X, Shi M, Wang Z, Cui L., Free PMC Article | 07/6/2019 |
| Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia | Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia.
Edin ML, Hamedani BG, Gruzdev A, Graves JP, Lih FB, Arbes SJ 3rd, Singh R, Orjuela Leon AC, Bradbury JA, DeGraff LM, Hoopes SL, Arand M, Zeldin DC., Free PMC Article | 01/12/2019 |
| The substrate specificity of microsomal epoxide hydrolase should therefore be expanded to include not only epoxides but also the oxetanyl ring system present in AZD1979. | Discovery of a Novel Microsomal Epoxide Hydrolase-Catalyzed Hydration of a Spiro Oxetane.
Li XQ, Hayes MA, Grönberg G, Berggren K, Castagnoli N Jr, Weidolf L. | 01/27/2018 |
| EPHX1 variants were significantly associated with higher metabolic ratio of carbamazepine | Effects of EPHX1 and CYP3A4*22 genetic polymorphisms on carbamazepine metabolism and drug response among Tunisian epileptic patients.
Chbili C, Fathallah N, Laouani A, Nouira M, Hassine A, Ben Amor S, Ben Ammou S, Ben Salem C, Saguem S. | 12/23/2017 |
| Single nucleotide polymorphisms in EPHX1, GSTP1, SERPINE2, and TGFB1 contributing to the quantitative traits of chronic obstructive pulmonary disease in Chinese Han population. | Exploring the interaction among EPHX1, GSTP1, SERPINE2, and TGFB1 contributing to the quantitative traits of chronic obstructive pulmonary disease in Chinese Han population.
An L, Lin Y, Yang T, Hua L., Free PMC Article | 12/2/2017 |
| This study showed that polymorphisms of EPHX1 and VKORC1L1 could be determinants of stable warfarin doses. | Polymorphisms of vitamin K-related genes (EPHX1 and VKORC1L1) and stable warfarin doses.
Chung JE, Lee KE, Chang BC, Gwak HS. | 11/25/2017 |
| The Tyr113His T/C variant of rs1051740 and very slow phenotype alters EPHX1, miR-26b-5p and miR-1207-5p expression, and contributes towards low blood iron levels and low birthweights. | The Tyr113His T/C rs1051740 and 'very slow' phenotype of the EPHX1 gene alters miR-26b-5p and miR-1207-5p expression in pregnancy.
Naidoo P, Naidoo RN, Ramkaran P, Asharam K, Chuturgoon AA. | 09/30/2017 |