HIF-2α expression and metabolic signaling require ACSS2 in clear cell renal cell carcinoma.
Bacigalupa ZA, Arner EN, Vlach LM, Wolf MM, Brown WA, Krystofiak ES, Ye X, Hongo RA, Landis M, Amason EK, Beckermann KE, Rathmell WK, Rathmell JC., Free PMC Article

Hypoxia-inducible factor-2α promotes fibrosis in non-alcoholic fatty liver disease by enhancing glutamine catabolism and inhibiting yes-associated protein phosphorylation in hepatic stellate cells.
Yan R, Cai H, Zhou X, Bao G, Bai Z, Ge RL., Free PMC Article

EPAS1-mutated paragangliomas associated with haemoglobin disorders.
Mancini M, Buffet A, Porte B, Amar L, Lussey-Lepoutre C, Crinière L, Baudin E, Meatchi T, Gimenez-Roqueplo AP, Favier J, Burnichon N.

Functional EPAS1/HIF2A missense variant is associated with hematocrit in Andean highlanders.
Lawrence ES, Gu W, Bohlender RJ, Anza-Ramirez C, Cole AM, Yu JJ, Hu H, Heinrich EC, O'Brien KA, Vasquez CA, Cowan QT, Bruck PT, Mercader K, Alotaibi M, Long T, Hall JE, Moya EA, Bauk MA, Reeves JJ, Kong MC, Salem RM, Vizcardo-Galindo G, Macarlupu JL, Figueroa-Mujíca R, Bermudez D, Corante N, Gaio E, Fox KP, Salomaa V, Havulinna AS, Murray AJ, Malhotra A, Powel FL, Jain M, Komor AC, Cavalleri GL, Huff CD, Villafuerte FC, Simonson TS., Free PMC Article

HIF-2α-dependent TGFBI promotes ovarian cancer chemoresistance by activating PI3K/Akt pathway to inhibit apoptosis and facilitate DNA repair process.
Ma S, Wang J, Cui Z, Yang X, Cui X, Li X, Zhao L., Free PMC Article

HIF-2α/LINC02609/APOL1-mediated lipid storage promotes endoplasmic reticulum homeostasis and regulates tumor progression in clear-cell renal cell carcinoma.
Xiao H, Qu Y, Li H, Zhang Y, Fei M, Liang C, Yang H, Zhang X., Free PMC Article

A Case-Control Study of the Associations between EGLN1 Gene Polymorphisms and COPD.
Li X, Zhang P, Yu J, Zhang C, Shi Y, Wei X, Li H, Zhang X, Lin A, Yang Z, Wang Y, Wang X.

Somatic EPAS1 Variants in Pheochromocytoma and Paraganglioma in Patients With Sickle Cell Disease.
White G, Nonaka D, Chung TT, Oakey RJ, Izatt L., Free PMC Article

Hypoxia-inducible factor 2α protein and mRNA expression correlate with histomorphological features in clear cell renal cell carcinoma.
Pham T, Ohe C, Yoshida T, Nakamoto T, Kinoshita H, Tsuta K.

UBE3B promotes breast cancer progression by antagonizing HIF-2α degradation.
Wang Y, Liu X, Wang M, Wang Y, Wang S, Jin L, Liu M, Zhou J, Chen Y.

Structural basis for binding of the renal carcinoma target hypoxia-inducible factor 2α to prolyl hydroxylase domain 2.
Figg WD Jr, Fiorini G, Chowdhury R, Nakashima Y, Tumber A, McDonough MA, Schofield CJ., Free PMC Article

On either side of homeostasis: EPAS1 gain- and loss-offunction mutations.
Prchal JT, Semenza GL., Free PMC Article

Oxygen-independent stabilization of HIF-2α in breast cancer through direct interaction with peptidyl-prolyl cis-trans isomerase NIMA-interacting 1.
Guillen-Quispe YN, Kim SJ, Saeidi S, Zhou T, Zheng J, Kim SH, Fang X, Chelakkot C, Rios-Castillo ME, Shin YK, Surh YJ.

A novel HIF2A mutation causes dyslipidemia and promotes hepatic lipid accumulation.
Gao F, Yao Q, Zhu J, Chen W, Feng X, Feng B, Wu J, Pacak K, Rosenblum J, Yu J, Zhuang Z, Cao H, Li L.,

High-Altitude Andean H194R HIF2A Allele Is a Hypomorphic Allele.
Jorgensen K, Song D, Weinstein J, Garcia OA, Pearson LN, Inclán M, Rivera-Chira M, León-Velarde F, Kiyamu M, Brutsaert TD, Bigham AW, Lee FS., Free PMC Article

Cytoplasmic HIF-2α as tissue biomarker to identify metastatic sympathetic paraganglioma.
Karakaya S, Gunnesson L, Elias E, Martos-Salvo P, Robledo M, Nilsson O, Wängberg B, Abel F, Påhlman S, Muth A, Mohlin S., Free PMC Article

USP10 Contributes to Colon Carcinogenesis via mTOR/S6K Mediated HIF-1α but Not HIF-2α Protein Synthesis.
Kubaichuk K, Kietzmann T., Free PMC Article

The association of hypoxia-inducible factor-1α and hypoxia-inducible factor-2α protein expression with clinicopathological characteristics in papillary thyroid carcinoma: A meta-analysis.
Lin X, Su H, Huo J, Zhang F., Free PMC Article

Overexpression of the Long Noncoding RNA HIF2PUT Inhibits Non-Small Cell Lung Cancer Cell Proliferation and Invasion Through HIF-2a Pathway.
Wang J, Tian Y, Yu M, Ma M, Gao Y.

EPAS1 resistance to miRNA-based regulation contributes to prolonged expression of HIF-2 during hypoxia in human endothelial cells.
Jaśkiewicz M, Moszyńska A, Gebert M, Collawn JF, Bartoszewski R.

Hypoxia Increases ATX Expression by Histone Crotonylation in a HIF-2α-Dependent Manner.
Qu M, Long Y, Wang Y, Yin N, Zhang X, Zhang J., Free PMC Article

HIF2α-induced upregulation of RNASET2 promotes triglyceride synthesis and enhances cell migration in clear cell renal cell carcinoma.
Quan Y, Dai J, Zhou S, Zhao L, Jin L, Long Y, Liu S, Hu Y, Liu Y, Zhao J, Ding Z., Free PMC Article

Endotyping COPD: hypoxia-inducible factor-2 as a molecular "switch" between the vascular and airway phenotypes?
Myronenko O, Foris V, Crnkovic S, Olschewski A, Rocha S, Nicolls MR, Olschewski H., Free PMC Article

The transition from HIF-1 to HIF-2 during prolonged hypoxia results from reactivation of PHDs and HIF1A mRNA instability.
Jaśkiewicz M, Moszyńska A, Króliczewski J, Cabaj A, Bartoszewska S, Charzyńska A, Gebert M, Dąbrowski M, Collawn JF, Bartoszewski R., Free PMC Article

HIF-2α-induced upregulation of CD36 promotes the development of ccRCC.
Liao M, Li Y, Xiao A, Lu Q, Zeng H, Qin H, Zheng E, Luo X, Chen L, Ruan XZ, Yang P, Chen Y.