| CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer. | CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.
Yuan X, Hao X, Chan HL, Zhao N, Pedroza DA, Liu F, Le K, Smith AJ, Calderon SJ, Lieu N, Soth MJ, Jones P, Zhang XH, Rosen JM., Free PMC Article | 10/30/2024 |
| AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer. | AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.
Sardar S, McNair CM, Ravindranath L, Chand SN, Yuan W, Bogdan D, Welti J, Sharp A, Ryan NK, Knudsen LA, Schiewer MJ, DeArment EG, Janas T, Su XA, Butler LM, de Bono JS, Frese K, Brooks N, Pegg N, Knudsen KE, Shafi AA., Free PMC Article | 10/30/2024 |
| KIF15 promotes human glioblastoma progression under the synergistic transactivation of REST and P300. | KIF15 promotes human glioblastoma progression under the synergistic transactivation of REST and P300.
Yu W, Han S, Hu S, Ru L, Hua C, Xue G, Zhang G, Lv K, Ge H, Wang M, Zheng L, Zhou J, Hou S, Teng Y, Deng W, Guo W., Free PMC Article | 10/22/2024 |
| EP300 promotes tumor stemness via epigenetic activation of CRISP3 leading to lobaplatin resistance in triple-negative breast cancer. | EP300 promotes tumor stemness via epigenetic activation of CRISP3 leading to lobaplatin resistance in triple-negative breast cancer.
Wang Y, Zhang Y, Qi X. | 08/23/2024 |
| P300 Participates in Ionizing Radiation-Mediated Activation of Cathepsin L by Mutant p53. | P300 Participates in Ionizing Radiation-Mediated Activation of Cathepsin L by Mutant p53.
Xiong YJ, Zhu Y, Liu YL, Zhao YF, Shen X, Zuo WQ, Lin F, Liang ZQ. | 07/29/2024 |
| P300 reduces TUBB4B expression to facilitate the biological process of migration and invasion of non-small cell lung cancer cells. | P300 reduces TUBB4B expression to facilitate the biological process of migration and invasion of non-small cell lung cancer cells.
Hu H, Zhang Y, Zhai H, Dong J, Zuo L, Guo X, Wang C. | 06/28/2024 |
| EP300 through upregulating the expression of vimentin to promote the progression of chordoma. | EP300 through upregulating the expression of vimentin to promote the progression of chordoma.
Wen L, Xie B, Li H, Huang J, Shi Y, Tao Y, Chen Y. | 05/6/2024 |
| P300 in schizophrenia: Then and now. | P300 in schizophrenia: Then and now.
Hamilton HK, Mathalon DH, Ford JM. | 04/25/2024 |
| EP300-ZNF384 transactivates IL3RA to promote the progression of B-cell acute lymphoblastic leukemia. | EP300-ZNF384 transactivates IL3RA to promote the progression of B-cell acute lymphoblastic leukemia.
Hou Z, Ren Y, Zhang X, Huang D, Yan F, Sun W, Zhang W, Zhang Q, Fu X, Lang Z, Chu C, Zou B, Gao B, Jin B, Kang Z, Liu Q, Yan J., Free PMC Article | 04/5/2024 |
| Acetyltransferase P300 Regulates Glucose Metabolic Reprogramming through Catalyzing Succinylation in Lung Cancer. | Acetyltransferase P300 Regulates Glucose Metabolic Reprogramming through Catalyzing Succinylation in Lung Cancer.
Ma Q, Zeng Q, Wang K, Qian M, Li J, Wang H, Zhang H, Jiang J, Chen Z, Huang W., Free PMC Article | 02/28/2024 |
| EP300 improves endothelial injury and mitochondrial dysfunction in coronary artery disease by regulating histone acetylation of SOCS1 promoter via inhibiting JAK/STAT pathway. | EP300 improves endothelial injury and mitochondrial dysfunction in coronary artery disease by regulating histone acetylation of SOCS1 promoter via inhibiting JAK/STAT pathway.
Xue W, Deng L. | 02/27/2024 |
| Upregulation of p300 in paclitaxel-resistant TNBC: implications for cell proliferation via the PCK1/AMPK axis. | Upregulation of p300 in paclitaxel-resistant TNBC: implications for cell proliferation via the PCK1/AMPK axis.
Zhao PW, Cui JX, Wang XM. | 02/23/2024 |
| Inhibition of p300 increases cytotoxicity of cisplatin in pancreatic cancer cells. | Inhibition of p300 increases cytotoxicity of cisplatin in pancreatic cancer cells.
Bugbee T, Gathoni M, Payne C, Blubaugh M, Matlock K, Wixson T, Lu A, Stancic S, Chung PA, Palinski R, Wallace N., | 02/15/2024 |
| HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis. | HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis.
Emmons MF, Bennett RL, Riva A, Gupta K, Carvalho LADC, Zhang C, Macaulay R, Dupéré-Richér D, Fang B, Seto E, Koomen JM, Li J, Chen YA, Forsyth PA, Licht JD, Smalley KSM., Free PMC Article | 01/31/2024 |
| NDUFA8 is transcriptionally regulated by EP300/H3K27ac and promotes mitochondrial respiration to support proliferation and inhibit apoptosis in cervical cancer. | NDUFA8 is transcriptionally regulated by EP300/H3K27ac and promotes mitochondrial respiration to support proliferation and inhibit apoptosis in cervical cancer.
Xiang H, Tang H, He Q, Sun J, Yang Y, Kong L, Wang Y. | 01/12/2024 |
| MiR-26a-5p exerts its influence by targeting EP300, a molecule known for its role in activating the PI3K/AKT/mTOR signaling pathway in CD8+tumor-infiltrating lymphocytes of colorectal cancer. | MiR-26a-5p exerts its influence by targeting EP300, a molecule known for its role in activating the PI3K/AKT/mTOR signaling pathway in CD8+tumor-infiltrating lymphocytes of colorectal cancer.
Wang C, Lin H, Zhao W, Liang Y, Chen Y, Wang C. | 01/5/2024 |
| The P300 Auditory Evoked Potential: A Physiological Measure of the Engagement of Cognitive Systems Contributing to Listening Effort? | The P300 Auditory Evoked Potential: A Physiological Measure of the Engagement of Cognitive Systems Contributing to Listening Effort?
Kestens K, Van Yper L, Degeest S, Keppler H. | 11/2/2023 |
| The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels. | The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.
Krošel M, Gabathuler M, Moser L, Maciukiewicz M, Züllig T, Seifritz T, Tomšič M, Distler O, Ospelt C, Klein K., Free PMC Article | 10/12/2023 |
| Deficient chaperone-mediated autophagy facilitates LPS-induced microglial activation via regulation of the p300/NF-kappaB/NLRP3 pathway. | Deficient chaperone-mediated autophagy facilitates LPS-induced microglial activation via regulation of the p300/NF-κB/NLRP3 pathway.
Wu J, Han Y, Xu H, Sun H, Wang R, Ren H, Wang G., Free PMC Article | 10/10/2023 |
| EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic cancer. | EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic cancer.
Wang Y, Liu Y, Wang C, Kang R, Tang D, Liu J., Free PMC Article | 09/28/2023 |
| Novel heterozygous variants in the EP300 gene cause Rubinstein-Taybi syndrome 2: Reports from two Chinese children. | Novel heterozygous variants in the EP300 gene cause Rubinstein-Taybi syndrome 2: Reports from two Chinese children.
Du C, Li Z, Zou B, Li X, Chen F, Liang Y, Luo X, Shu S., Free PMC Article | 09/27/2023 |
| LPCAT3 Is Transcriptionally Regulated by YAP/ZEB/EP300 and Collaborates with ACSL4 and YAP to Determine Ferroptosis Sensitivity. | LPCAT3 Is Transcriptionally Regulated by YAP/ZEB/EP300 and Collaborates with ACSL4 and YAP to Determine Ferroptosis Sensitivity.
Cui J, Wang Y, Tian X, Miao Y, Ma L, Zhang C, Xu X, Wang J, Fang W, Zhang X. | 09/19/2023 |
| The deubiquitinase UCHL3 mediates p300-dependent chemokine signaling in alveolar type II cells to promote pulmonary fibrosis. | The deubiquitinase UCHL3 mediates p300-dependent chemokine signaling in alveolar type II cells to promote pulmonary fibrosis.
Lee SY, Park SY, Lee SH, Kim H, Kwon JH, Yoo JY, Kim K, Park MS, Lee CG, Elias JA, Sohn MH, Shim HS, Yoon HG., Free PMC Article | 09/8/2023 |
| TAZ2 truncation confers overactivation of p300 and cellular vulnerability to HDAC inhibition. | TAZ2 truncation confers overactivation of p300 and cellular vulnerability to HDAC inhibition.
Xu L, Xuan H, He W, Zhang L, Huang M, Li K, Wen H, Xu H, Shi X., Free PMC Article | 09/7/2023 |
| EP300 as a Molecular Integrator of Fibrotic Transcriptional Programs. | EP300 as a Molecular Integrator of Fibrotic Transcriptional Programs.
Rubio K, Molina-Herrera A, Pérez-González A, Hernández-Galdámez HV, Piña-Vázquez C, Araujo-Ramos T, Singh I., Free PMC Article | 08/14/2023 |