| Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1. | Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1.
Huang J, Jiang Y, Ji R, Jia Y, Wang S, Zhou Z, Wang S, Wang J, Yang Q, Bai H, Zhu X, Jiang B, Ben J, Zhang H, Li X, Chen Q. | 07/7/2023 |
| MSR1 is not required for obesity-associated inflammation and insulin resistance in mice. | MSR1 is not required for obesity-associated inflammation and insulin resistance in mice.
Nance SA, Muir L, Delproprosto J, Lumeng CN., Free PMC Article | 02/16/2023 |
| Role of macrophage scavenger receptor MSR1 in the progression of non-alcoholic steatohepatitis. | Role of macrophage scavenger receptor MSR1 in the progression of non-alcoholic steatohepatitis.
Sheng W, Ji G, Zhang L., Free PMC Article | 01/14/2023 |
| SRA Suppresses Antiviral Innate Immune Response in Macrophages by Limiting TBK1 K63 Ubiquitination via Deubiquitinase USP15. | SRA Suppresses Antiviral Innate Immune Response in Macrophages by Limiting TBK1 K63 Ubiquitination via Deubiquitinase USP15.
Li L, Luo J, Zhu Z, Xu Q, Wang P, Chang B, Wang D, Yu L, Lu X, Zhou J, Zuo D, Chen Q., Free PMC Article | 01/7/2023 |
| Blocking Msr1 by berberine alkaloids inhibits caspase-11-dependent coagulation in bacterial sepsis. | Blocking Msr1 by berberine alkaloids inhibits caspase-11-dependent coagulation in bacterial sepsis.
Yuan C, Wu M, Xiao Q, Zhao W, Li H, Zhong Y, Zhao M, Li C, Li Y, Yang X., Free PMC Article | 03/26/2022 |
| The CD36 and SR-A/CD204 scavenger receptors fine-tune Staphylococcus aureus-stimulated cytokine production in mouse macrophages. | The CD36 and SR-A/CD204 scavenger receptors fine-tune Staphylococcus aureus-stimulated cytokine production in mouse macrophages.
Peruń A, Gębicka M, Biedroń R, Skalska P, Józefowski S. | 03/5/2022 |
| The role of macrophage scavenger receptor 1 (Msr1) in prion pathogenesis. | The role of macrophage scavenger receptor 1 (Msr1) in prion pathogenesis.
Li B, Chen M, Aguzzi A, Zhu C., Free PMC Article | 01/22/2022 |
| Critical contribution of macrophage scavenger receptor 1 to the uptake of nanostructured DNA by immune cells. | Critical contribution of macrophage scavenger receptor 1 to the uptake of nanostructured DNA by immune cells.
Umemura K, Ohtsuki S, Nagaoka M, Kusamori K, Inoue T, Takahashi Y, Takakura Y, Nishikawa M. | 01/15/2022 |
| Scavenger receptor A1 participates in uptake of Leptospira interrogans serovar Autumnalis strain 56606v and inflammation in mouse macrophages. | Scavenger receptor A1 participates in uptake of Leptospira interrogans serovar Autumnalis strain 56606v and inflammation in mouse macrophages.
Wang Y, Fan X, Du L, Liu B, Xiao H, Zhang Y, Wu Y, Liu F, Chang YF, Guo X, He P., Free PMC Article | 11/6/2021 |
| Glycoursodeoxycholic Acid Ameliorates Atherosclerosis and Alters Gut Microbiota in Apolipoprotein E-Deficient Mice. | Glycoursodeoxycholic Acid Ameliorates Atherosclerosis and Alters Gut Microbiota in Apolipoprotein E-Deficient Mice.
Huang K, Liu C, Peng M, Su Q, Liu R, Guo Z, Chen S, Li Z, Chang G., Free PMC Article | 10/23/2021 |
| Class A scavenger receptor-1/2 facilitates the uptake of bovine milk exosomes in murine bone marrow-derived macrophages and C57BL/6J mice. | Class A scavenger receptor-1/2 facilitates the uptake of bovine milk exosomes in murine bone marrow-derived macrophages and C57BL/6J mice.
Khanam A, Yu J, Zempleni J., Free PMC Article | 09/25/2021 |
| Macrophage scavenger receptor 1 controls Chikungunya virus infection through autophagy in mice. | Macrophage scavenger receptor 1 controls Chikungunya virus infection through autophagy in mice.
Yang L, Geng T, Yang G, Ma J, Wang L, Ketkar H, Yang D, Lin T, Hwang J, Zhu S, Wang Y, Dai J, You F, Cheng G, Vella AT, Flavell RA, Fikrig E, Wang P., Free PMC Article | 06/26/2021 |
| Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1. | Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1.
Arsiwala T, Pahla J, van Tits LJ, Bisceglie L, Gaul DS, Costantino S, Miranda MX, Nussbaum K, Stivala S, Blyszczuk P, Weber J, Tailleux A, Stein S, Paneni F, Beer JH, Greter M, Becher B, Mostoslavsky R, Eriksson U, Staels B, Auwerx J, Hottiger MO, Lüscher TF, Matter CM. | 01/23/2021 |
| Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury. | Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury.
Kong FQ, Zhao SJ, Sun P, Liu H, Jie J, Xu T, Xu AD, Yang YQ, Zhu Y, Chen J, Zhou Z, Qian DF, Gu CJ, Chen Q, Yin GY, Zhang HW, Fan J., Free PMC Article | 12/12/2020 |
| Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF3 ubiquitination through recruiting OTUB1. | Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF3 ubiquitination through recruiting OTUB1.
Xie M, Yin Y, Chen L, Yin A, Liu Y, Liu Y, Dong L, Lai Q, Zhou J, Zhang L, Xu M, Chen Z, Zuo D. | 10/24/2020 |
| Scavenger receptor-A is a biomarker and effector of rheumatoid arthritis. | Scavenger receptor-A is a biomarker and effector of rheumatoid arthritis: A large-scale multicenter study.
Hu F, Jiang X, Guo C, Li Y, Chen S, Zhang W, Du Y, Wang P, Zheng X, Fang X, Li X, Song J, Xie Y, Huang F, Xue J, Bai M, Jia Y, Liu X, Ren L, Zhang X, Guo J, Pan H, Su Y, Yi H, Ye H, Zuo D, Li J, Wu H, Wang Y, Li R, Liu L, Wang XY, Li Z., Free PMC Article | 08/13/2020 |
| These data suggest that Hrh2 signaling is required for effective phagocytosis by regulating the process of autophagy and scavenger receptor MSR1 abundance in macrophages. | Phagocytosis by macrophages depends on histamine H2 receptor signaling and scavenger receptor 1.
Fultz R, Engevik MA, Shi Z, Hall A, Herrmann B, Ganesh BP, Major A, Haag A, Mori-Akiyama Y, Versalovic J., Free PMC Article | 06/27/2020 |
| Glycosylation of SR-A was largely attenuated by Sac1 knockdown, but neither mRNA expression nor protein degradation of SR-A were affected. These results suggest that Sac1 maintains SR-A protein levels by modulating SR-A glycosylation. | Sac1 Phosphoinositide Phosphatase Regulates Foam Cell Formation by Modulating SR-A Expression in Macrophages.
Nigorikawa K, Matsumura T, Sakamoto H, Morioka S, Kofuji S, Takasuga S, Hazeki K. | 11/30/2019 |
| The results indicated that SR-A1 stimulation, at least in part, plays a role in advanced glycation end products uptake by macrophages. | Effects of scavenger receptors-1 class A stimulation on macrophage morphology and highly modified advanced glycation end product-protein phagocytosis.
Hamasaki S, Kobori T, Yamazaki Y, Kitaura A, Niwa A, Nishinaka T, Nishibori M, Mori S, Nakao S, Takahashi H., Free PMC Article | 10/5/2019 |
| Genetic deletion of Msr1 or feeding fucoidan, a natural product ligand of MSR1, both worsened insulin resistance and blood glucose control. | Targeting macrophage scavenger receptor 1 promotes insulin resistance in obese male mice.
Cavallari JF, Anhê FF, Foley KP, Denou E, Chan RW, Bowdish DME, Schertzer JD., Free PMC Article | 09/21/2019 |
| identified SR-AI as a novel macrophage-specific receptor for von Willebrand factor. Enhanced binding of von Willebrand factor mutants to SR-AI may contribute to the increased clearance of these mutants. | Macrophage scavenger receptor SR-AI contributes to the clearance of von Willebrand factor.
Wohner N, Muczynski V, Mohamadi A, Legendre P, Proulle V, Aymé G, Christophe OD, Lenting PJ, Denis CV, Casari C., Free PMC Article | 07/20/2019 |
| Msr1 promotes the pathogenesis of virus-induced FH by enhancing induction of neutrophil NETosis and subsequent complement activation. | Macrophage scavenger receptor 1 contributes to pathogenesis of fulminant hepatitis via neutrophil-mediated complement activation.
Tang Y, Li H, Li J, Liu Y, Li Y, Zhou J, Zhou J, Lu X, Zhao W, Hou J, Wang XY, Chen Z, Zuo D., Free PMC Article | 07/13/2019 |
| Our results indicate that reduced expression of SR-A can deregulate glial inflammatory response and potentiate Abeta accumulation, two mechanisms that could contribute to Alzheimer disease progression. | Scavenger Receptor-A deficiency impairs immune response of microglia and astrocytes potentiating Alzheimer's disease pathophysiology.
Cornejo F, Vruwink M, Metz C, Muñoz P, Salgado N, Poblete J, Andrés ME, Eugenín J, von Bernhardi R. | 04/27/2019 |
| Custom-produced fluorescently labeled versions of MOG or MDA-modified MOG was used to study and quantify the uptake by different macrophage populations (especially anti-inflammatory M2-type macrophages) and to identify the responsible receptor, namely SRA. The SRA-mediated uptake of MDA-modified MOG is roughly tenfold more efficient compared to that of the native form. | Scavenger Receptor A Mediates the Clearance and Immunological Screening of MDA-Modified Antigen by M2-Type Macrophages.
Warnecke A, Abele S, Musunuri S, Bergquist J, Harris RA., Free PMC Article | 07/21/2018 |
| TMP upregulated the protein stability of ABCA1 without affecting ABCG1. Accordingly, TMP regulated the expression of SR-A, CD36, ABCA1 and ABCG1 in aortas of ApoE-/- mice, which resembled the findings observed in macrophages. | Tetramethylpyrazine suppresses lipid accumulation in macrophages via upregulation of the ATP-binding cassette transporters and downregulation of scavenger receptors.
Duan J, Xiang D, Luo H, Wang G, Ye Y, Yu C, Li X. | 07/7/2018 |