SCD1 promotes the stemness of gastric cancer stem cells by inhibiting ferroptosis through the SQLE/cholesterol/mTOR signalling pathway.
Mao X, Wang L, Chen Z, Huang H, Chen J, Su J, Li Z, Shen G, Ren Y, Li Z, Wang W, Ou J, Guo W, Hu Y.

Active AKT2 stimulation of SREBP1/SCD1-mediated lipid metabolism boosts hepatosteatosis and cancer.
Huang F, Zhao N, Cai P, Hou M, Yang S, Zheng B, Ma Q, Jiang J, Gai X, Mao Y, Wang L, Hu Z, Zha X, Liu F, Zhang H.

Scd1 and monounsaturated lipids are required for autophagy and survival of adipocytes.
Mori H, Peterson SK, Simmermon RC, Overmyer KA, Nishii A, Paulsson E, Li Z, Jen A, Uranga RM, Maung JN, Yacawych WT, Lewis KT, Schill RL, Hetrick T, Seino R, Inoki K, Coon JJ, MacDougald OA., Free PMC Article

Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolites.
Cavallero S, Roustaei M, Satta S, Cho JM, Phan H, Baek KI, Blázquez-Medela AM, Gonzalez-Ramos S, Vu K, Park SK, Yokota T, Sumner J, Mack JJ, Sigmund CD, Reddy ST, Li R, Hsiai TK., Free PMC Article

SCD1 inhibition enhances the effector functions of CD8(+) T cells via ACAT1-dependent reduction of esterified cholesterol.
Sugi T, Katoh Y, Ikeda T, Seta D, Iwata T, Nishio H, Sugawara M, Kato D, Katoh K, Kawana K, Yaguchi T, Kawakami Y, Hirai S., Free PMC Article

SCD1-related epigenetic modifications affect hormone-sensitive lipase (Lipe) gene expression in cardiomyocytes.
Olichwier A, Sowka A, Balatskyi VV, Gan AM, Dziewulska A, Dobrzyn P.

Dynamic role of Scd1 gene during mouse oocyte growth and maturation.
Niu H, An X, Wang X, Yang M, Cheng F, Lei A, Luo J.

Stearoyl-CoA desaturase 1 deficiency exacerbates palmitate-induced lipotoxicity by the formation of small lipid droplets in pancreatic β-cells.
Janikiewicz J, Dobosz AM, Majzner K, Bernas T, Dobrzyn A.

Lrig1-expressing epidermal progenitors require SCD1 to maintain the dermal papilla niche.
Lim SBH, Wei S, Tan AH, van Steensel MAM, Lim X., Free PMC Article

SCD1 Sustains Homeostasis of Bulge Niche via Maintaining Hemidesmosomes in Basal Keratinocytes.
Xue Y, Lin L, Li Q, Liu K, Hu M, Ye J, Cao J, Zhai J, Zheng F, Wang Y, Zhang T, Du L, Gao C, Wang G, Wang X, Qin J, Liao X, Kong X, Sorokin L, Shi Y, Wang Y., Free PMC Article

Inhibition of stearoyl-CoA desaturase 1 in the mouse impairs pancreatic islet morphogenesis and promotes loss of β-cell identity and α-cell expansion in the mature pancreas.
Dobosz AM, Janikiewicz J, Krogulec E, Dziewulska A, Ajduk A, Szpila M, Nieznańska H, Szczepankiewicz AA, Wypych D, Dobrzyn A., Free PMC Article

Effects of CRISPR/Cas9-mediated stearoyl-Coenzyme A desaturase 1 knockout on mouse embryo development and lipid synthesis.
Tian H, Niu H, Luo J, Yao W, Gao W, Wen Y, Cheng M, Lei A, Hua J., Free PMC Article

Saprophytic bacteria and fungi colonize stearoyl coenzyme-A desaturase-1 knockout skin.
Pyle HJ, Artami M, Edwards M, Raj P, Zhang B, Arana C, Harris-Tryon TA.

Airway epithelial STAT3 inhibits allergic inflammation via upregulation of stearoyl-CoA desaturase 1.
Nishimura N, Yokota M, Kurihara S, Iwata A, Kageyama T, Ito T, Saku A, Maezawa Y, Hirose K, Nakajima H.

SCD1 is nutritionally and spatially regulated in the intestine and influences systemic postprandial lipid homeostasis and gut-liver crosstalk.
Burchat N, Akal T, Ntambi JM, Trivedi N, Suresh R, Sampath H., Free PMC Article

Blockage of NDUFB9-SCD1 pathway inhibits adipogenesis : Blockage of NDUFB9-SCD1 pathway inhibits adipogenesis.
Zhu S, Zhang J, Wang W, Jiang X, Chen YQ.

Early-life exposure to bisphenol A induces dysregulation of lipid homeostasis by the upregulation of SCD1 in male mice.
Fang R, Yang S, Gu X, Li C, Bi N, Wang HL.

A CD10-OGP Membrane Peptolytic Signaling Axis in Fibroblasts Regulates Lipid Metabolism of Cancer Stem Cells via SCD1.
Yu S, Lu Y, Su A, Chen J, Li J, Zhou B, Liu X, Xia Q, Li Y, Li J, Huang M, Ye Y, Zhao Q, Jiang S, Yan X, Wang X, Di C, Pan J, Su S., Free PMC Article

Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity.
Zhou X, Zhu X, Li C, Li Y, Ye Z, Shapiro VS, Copland JA 3rd, Hitosugi T, Bernlohr DA, Sun J, Zeng H., Free PMC Article

SCD1 promotes lipid mobilization in subcutaneous white adipose tissue.
Zou Y, Wang YN, Ma H, He ZH, Tang Y, Guo L, Liu Y, Ding M, Qian SW, Tang QQ., Free PMC Article

Stearoyl-CoA Desaturase (SCD) Induces Cardiac Dysfunction with Cardiac Lipid Overload and Angiotensin II AT1 Receptor Protein Up-Regulation.
Abd Alla J, Jamous YF, Quitterer U., Free PMC Article

Metabolic rerouting via SCD1 induction impacts X-linked adrenoleukodystrophy.
Raas Q, van de Beek MC, Forss-Petter S, Dijkstra IM, Deschiffart A, Freshner BC, Stevenson TJ, Jaspers YR, Nagtzaam L, Wanders RJ, van Weeghel M, Engelen-Lee JY, Engelen M, Eichler F, Berger J, Bonkowsky JL, Kemp S., Free PMC Article

Interplay between Thyroid Hormones and Stearoyl-CoA Desaturase 1 in the Regulation of Lipid Metabolism in the Heart.
Olichwier A, Balatskyi VV, Wolosiewicz M, Ntambi JM, Dobrzyn P., Free PMC Article

Saturated and monounsaturated fatty acids in membranes are determined by the gene expression of their metabolizing enzymes SCD1 and ELOVL6 regulated by the intake of dietary fat.
Weiss-Hersh K, Garcia AL, Marosvölgyi T, Szklenár M, Decsi T, Rühl R., Free PMC Article

MiR-99b-5p Attenuates Adipogenesis by Targeting SCD1 and Lpin1 in 3T3-L1 Cells.
Xu Y, Chen X, Zhao C, Wang X, Cheng Y, Xi F, Yao X, Zhang L, Yang G, Yu T.