| SATB1 prevents immune cell infiltration by regulating chromatin organization and gene expression of a chemokine gene cluster in T cells. | SATB1 prevents immune cell infiltration by regulating chromatin organization and gene expression of a chemokine gene cluster in T cells.
Wang B, Bian Q., Free PMC Article | 10/22/2024 |
| Long Non-Coding RNA ANRIL Regulates Inflammatory Factor Expression in Ulcerative Colitis Via the miR-191-5p/SATB1 Axis. | Long Non-Coding RNA ANRIL Regulates Inflammatory Factor Expression in Ulcerative Colitis Via the miR-191-5p/SATB1 Axis.
Yu KQ, Li CF, Ye L, Song Y, Wang YH, Lin YR, Liao ST, Mei ZC, Lv L. | 05/31/2024 |
| A dual function for the chromatin organizer Special A-T rich Binding Protein 1 in B-lineage cells. | A dual function for the chromatin organizer Special A-T rich Binding Protein 1 in B-lineage cells.
Thomas M, Bruzeau C, Martin OA, Pollet J, Bender S, Carrion C, Le Noir S, Pinaud E., Free PMC Article | 03/21/2024 |
| SATB1 regulates 3D genome architecture in T cells by constraining chromatin interactions surrounding CTCF-binding sites. | SATB1 regulates 3D genome architecture in T cells by constraining chromatin interactions surrounding CTCF-binding sites.
Wang B, Ji L, Bian Q. | 10/6/2023 |
| Crucial Roles of SATB1 in Regulation of Thymocyte Migration after Positive Selection. | Crucial Roles of SATB1 in Regulation of Thymocyte Migration after Positive Selection.
Naito T, Ise M, Tanaka Y, Kohwi-Shigematsu T, Kondo M. | 07/19/2023 |
| Identification of a novel enhancer essential for Satb1 expression in TH2 cells and activated ILC2s. | Identification of a novel enhancer essential for Satb1 expression in T(H)2 cells and activated ILC2s.
Nomura A, Kobayashi T, Seo W, Ohno-Oishi M, Kakugawa K, Muroi S, Yoshida H, Endo TA, Moro K, Taniuchi I., Free PMC Article | 05/19/2023 |
| The role of selective SATB1 deletion in somatostatin expressing interneurons on endogenous network activity and the transition to epilepsy. | The role of selective SATB1 deletion in somatostatin expressing interneurons on endogenous network activity and the transition to epilepsy.
Vasilopoulos N, Kaplanian A, Vinos M, Katsaiti Y, Christodoulou O, Denaxa M, Skaliora I. | 02/17/2023 |
| Reduced Satb1 expression predisposes CD4(+) T conventional cells to Treg suppression and promotes transplant survival. | Reduced Satb1 expression predisposes CD4(+) T conventional cells to Treg suppression and promotes transplant survival.
Gupta PK, Allocco JB, Fraipont JM, McKeague ML, Wang P, Andrade MS, McIntosh C, Chen L, Wang Y, Li Y, Andrade J, Conejo-Garcia JR, Chong AS, Alegre ML., Free PMC Article | 10/15/2022 |
| SATB1 ensures appropriate transcriptional programs within naive CD8(+) T cells. | SATB1 ensures appropriate transcriptional programs within naïve CD8(+) T cells.
Nüssing S, Miosge LA, Lee K, Olshansky M, Barugahare A, Roots CM, Sontani Y, Day EB, Koutsakos M, Kedzierska K, Goodnow CC, Russ BE, Daley SR, Turner SJ., Free PMC Article | 09/17/2022 |
| Special AT-Rich Sequence-Binding Protein 1 Supports Survival and Maturation of Naive B Cells Stimulated by B Cell Receptors. | Special AT-Rich Sequence-Binding Protein 1 Supports Survival and Maturation of Naive B Cells Stimulated by B Cell Receptors.
Ozawa T, Fujii K, Sudo T, Doi Y, Nakai R, Shingai Y, Ueda T, Baba Y, Hosen N, Yokota T. | 04/30/2022 |
| TGF-beta-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures. | TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures.
Chaurio RA, Anadon CM, Lee Costich T, Payne KK, Biswas S, Harro CM, Moran C, Ortiz AC, Cortina C, Rigolizzo KE, Sprenger KB, Mine JA, Innamarato P, Mandal G, Powers JJ, Martin A, Wang Z, Mehta S, Perez BA, Li R, Robinson J, Kroeger JL, Curiel TJ, Yu X, Rodriguez PC, Conejo-Garcia JR., Free PMC Article | 02/26/2022 |
| SATB1-dependent mitochondrial ROS production controls TCR signaling in CD4 T cells. | SATB1-dependent mitochondrial ROS production controls TCR signaling in CD4 T cells.
Kuwabara T, Ishikawa F, Ikeda M, Ide T, Kohwi-Shigematsu T, Tanaka Y, Kondo M., Free PMC Article | 02/12/2022 |
| Methyltransferase inhibitors restore SATB1 protective activity against cutaneous T cell lymphoma in mice. | Methyltransferase inhibitors restore SATB1 protective activity against cutaneous T cell lymphoma in mice.
Harro CM, Perez-Sanz J, Costich TL, Payne KK, Anadon CM, Chaurio RA, Biswas S, Mandal G, Rigolizzo KE, Sprenger KB, Mine JA, Showe LC, Yu X, Liu K, Rodriguez PC, Pinilla-Ibarz J, Sokol L, Conejo-Garcia JR., Free PMC Article | 09/11/2021 |
| Role of Satb1 and Satb2 Transcription Factors in the Glutamate Receptors Expression and Ca(2+) Signaling in the Cortical Neurons In Vitro. | Role of Satb1 and Satb2 Transcription Factors in the Glutamate Receptors Expression and Ca(2+) Signaling in the Cortical Neurons In Vitro.
Turovsky EA, Turovskaya MV, Fedotova EI, Babaev AA, Tarabykin VS, Varlamova EG., Free PMC Article | 07/24/2021 |
| SATB1-mediated chromatin landscape in T cells. | SATB1-mediated chromatin landscape in T cells.
Zelenka T, Spilianakis C., Free PMC Article | 06/5/2021 |
| Dynamic regulation of chromatin organizer SATB1 via TCR-induced alternative promoter switch during T-cell development. | Dynamic regulation of chromatin organizer SATB1 via TCR-induced alternative promoter switch during T-cell development.
Patta I, Madhok A, Khare S, Gottimukkala KP, Verma A, Giri S, Dandewad V, Seshadri V, Lal G, Misra-Sen J, Galande S., Free PMC Article | 09/12/2020 |
| The data show that SATB1 is essential for establishing secretory ameloblast cell polarity and for EMP secretion. In line with the deformed apical architecture, amelogenin transport to the apical secretory front and secretion into enamel space were impeded in Satb1(-/-) SABs resulting in a massive cytoplasmic accumulation of amelogenins and a thin layer of hypomineralized enamel. | SATB1 establishes ameloblast cell polarity and regulates directional amelogenin secretion for enamel formation.
Zhang Y, Zheng L, Le M, Nakano Y, Chan B, Huang Y, Torbaty PM, Kohwi Y, Marcucio R, Habelitz S, Den Besten PK, Kohwi-Shigematsu T., Free PMC Article | 05/16/2020 |
| SATB1 levels regulate the maintenance of Hematopoietic stem cells multipotency, with variations contributing to Hematopoietic stem cells heterogeneity. | Variable SATB1 Levels Regulate Hematopoietic Stem Cell Heterogeneity with Distinct Lineage Fate.
Doi Y, Yokota T, Satoh Y, Okuzaki D, Tokunaga M, Ishibashi T, Sudo T, Ueda T, Shingai Y, Ichii M, Tanimura A, Ezoe S, Shibayama H, Kohwi-Shigematsu T, Takeda J, Oritani K, Kanakura Y. | 11/9/2019 |
| Satb1 regulates the specific gene expression and function of effector Th17 cells in tissue inflammation. | Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation.
Yasuda K, Kitagawa Y, Kawakami R, Isaka Y, Watanabe H, Kondoh G, Kohwi-Shigematsu T, Sakaguchi S, Hirota K., Free PMC Article | 04/6/2019 |
| Study using a mouse model with reduced IL-2 signaling revealed that IL-2, possibly through the positioning of the genome organizer SATB1, modulates thymic-derived Treg cell epigenetic identity prior to Foxp3 expression. | Interleukin 2 modulates thymic-derived regulatory T cell epigenetic landscape.
Chorro L, Suzuki M, Chin SS, Williams TM, Snapp EL, Odagiu L, Labrecque N, Lauvau G., Free PMC Article | 01/19/2019 |
| SATB1 is essential for maintaining TCR responsiveness during the induction and effector phases and may provide a novel therapeutic target for T cell-mediated autoimmune diseases. | Special AT-rich sequence binding protein 1 is required for maintenance of T cell receptor responsiveness and development of experimental autoimmune encephalomyelitis.
Akiba Y, Kuwabara T, Mukozu T, Mikami T, Kondo M., Free PMC Article | 09/15/2018 |
| SATB1 shapes the primary T cell pool by directing lineage-specific transcriptional programs in the thymus. | Essential Roles of SATB1 in Specifying T Lymphocyte Subsets.
Kakugawa K, Kojo S, Tanaka H, Seo W, Endo TA, Kitagawa Y, Muroi S, Tenno M, Yasmin N, Kohwi Y, Sakaguchi S, Kowhi-Shigematsu T, Taniuchi I. | 02/24/2018 |
| SATB1cKO mice, in which the SATB1 gene is specifically deleted from hematopoietic cells, develop Sjogren syndrome by 4 wk of age, soon after weaning. | SATB1 Conditional Knockout Results in Sjögren's Syndrome in Mice.
Tanaka Y, Sotome T, Inoue A, Mukozu T, Kuwabara T, Mikami T, Kowhi-Shigematsu T, Kondo M. | 12/30/2017 |
| RHS6 is a critical regulatory element for allergic airway inflammation and for coordinate regulation of Th2 cytokine genes by recruiting GATA3, SATB1, and IRF4. | RHS6 coordinately regulates the Th2 cytokine genes by recruiting GATA3, SATB1, and IRF4.
Hwang SS, Jang SW, Lee KO, Kim HS, Lee GR. | 12/9/2017 |
| these results identify a role for Satb1 in the lineage choice between pluripotency and differentiation and further our understanding of early embryonic lineage segregation. | The chromatin modifier Satb1 regulates cell fate through Fgf signalling in the early mouse embryo.
Goolam M, Zernicka-Goetz M., Free PMC Article | 09/16/2017 |