Engrailed-1 Promotes Pancreatic Cancer Metastasis.
Xu J, Roe JS, Lee E, Tonelli C, Ji KY, Younis OW, Somervile TDD, Yao M, Milazzo JP, Tiriac H, Kolarzyk AM, Lee E, Grem JL, Lazenby AJ, Grunkemeyer JA, Hollingsworth MA, Grandgenett PM, Borowsky AD, Park Y, Vakoc CR, Tuveson DA, Hwang CI., Free PMC Article

TGFβ-induced EN1 promotes tumor budding of adenoid cystic carcinoma in patient-derived organoid model.
Hui Z, Wang B, Liu Z, Wei J, Gan J, Landstrom M, Mu Y, Zang G.

[En1 promotes cell proliferation and migration via Hedgehog signaling pathway in esophageal squamous cell carcinoma].
Zhao N, Gong TY, Wei ZC, Cong J, Liu ZH, Chen HY.

The osteoporosis susceptibility SNP rs188303909 at 2q14.2 regulates EN1 expression by modulating DNA methylation and E2F6 binding.
Wang Y, Huang X, Zhang Q, Cheng C, Qin Z, Lu L, Huang Q.

EN1 Regulates Cell Growth and Proliferation in Human Glioma Cells via Hedgehog Signaling.
Chang J, Guo C, Li J, Liang Z, Wang Y, Yu A, Liu R, Guo Y, Chen J, Huang S., Free PMC Article

Converting fibroblastic fates leads to wound healing without scar.
Jiang D, Rinkevich Y., Free PMC Article

Repeated mutation of a developmental enhancer contributed to human thermoregulatory evolution.
Aldea D, Atsuta Y, Kokalari B, Schaffner SF, Prasasya RD, Aharoni A, Dingwall HL, Warder B, Kamberov YG., Free PMC Article

Engrailed 1 coordinates cytoskeletal reorganization to induce myofibroblast differentiation.
Györfi AH, Matei AE, Fuchs M, Liang C, Rigau AR, Hong X, Zhu H, Luber M, Bergmann C, Dees C, Ludolph I, Horch RE, Distler O, Wang J, Bengsch B, Schett G, Kunz M, Distler JHW., Free PMC Article

Homeobox transcription factor engrailed homeobox 1 is a possible diagnostic marker for adenoid cystic carcinoma and polymorphous adenocarcinoma.
Baba S, Akashi T, Kayamori K, Ohuchi T, Ogawa I, Kubota N, Nakano K, Nagatsuka H, Hasegawa H, Matsuzaka K, Tomii S, Uchida K, Katsuta N, Sekiya T, Ando N, Miura K, Ishibashi H, Ariizumi Y, Asakage T, Michi Y, Harada H, Sakamoto K, Eishi Y, Okubo K, Ikeda T.

Engrailed Homeobox 1 and Cytokeratin 19 Are Independent Diagnostic Markers of Eccrine Porocarcinoma and Distinguish It From Squamous Cell Carcinoma.
Miura K, Akashi T, Namiki T, Hishima T, Bae Y, Sakurai U, Murano K, Shiraishi J, Warabi M, Tanizawa T, Tanaka M, Bhunchet E, Kumagai J, Ayabe S, Sekiya T, Ando N, Shintaku H, Kinowaki Y, Tomii S, Kirimura S, Kayamori K, Yamamoto K, Ito T, Eishi Y.

EN1 Is a Transcriptional Dependency in Triple-Negative Breast Cancer Associated with Brain Metastasis.
Peluffo G, Subedee A, Harper NW, Kingston N, Jovanović B, Flores F, Stevens LE, Beca F, Trinh A, Chilamakuri CSR, Papachristou EK, Murphy K, Su Y, Marusyk A, D'Santos CS, Rueda OM, Beck AH, Caldas C, Carroll JS, Polyak K., Free PMC Article

Engrailed 1 overexpression as a potential prognostic marker in quintuple-negative breast cancer.
Kim YJ, Sung M, Oh E, Vrancken MV, Song JY, Jung K, Choi YL., Free PMC Article

Homeobox transcriptional factor engrailed homeobox 1 is expressed specifically in normal and neoplastic sweat gland cells.
Miura K, Akashi T, Ando N, Ayabe S, Kayamori K, Namiki T, Eishi Y.

Association between EN1 rs4144782 and susceptibility of knee osteoarthritis: A case-control study.
Li H, Zhang X, Cao Y, Hu S, Peng F, Zhou J, Li J., Free PMC Article

FGFR Inhibitor Ameliorates Hypophosphatemia and Impaired Engrailed-1/Wnt Signaling in FGF2 High Molecular Weight Isoform Transgenic Mice.
Du E, Xiao L, Hurley MM.

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.
Zheng HF, Forgetta V, Hsu YH, Estrada K, Rosello-Diez A, Leo PJ, Dahia CL, Park-Min KH, Tobias JH, Kooperberg C, Kleinman A, Styrkarsdottir U, Liu CT, Uggla C, Evans DS, Nielson CM, Walter K, Pettersson-Kymmer U, McCarthy S, Eriksson J, Kwan T, Jhamai M, Trajanoska K, Memari Y, Min J, Huang J, Danecek P, Wilmot B, Li R, Chou WC, Mokry LE, Moayyeri A, Claussnitzer M, Cheng CH, Cheung W, Medina-Gómez C, Ge B, Chen SH, Choi K, Oei L, Fraser J, Kraaij R, Hibbs MA, Gregson CL, Paquette D, Hofman A, Wibom C, Tranah GJ, Marshall M, Gardiner BB, Cremin K, Auer P, Hsu L, Ring S, Tung JY, Thorleifsson G, Enneman AW, van Schoor NM, de Groot LC, van der Velde N, Melin B, Kemp JP, Christiansen C, Sayers A, Zhou Y, Calderari S, van Rooij J, Carlson C, Peters U, Berlivet S, Dostie J, Uitterlinden AG, Williams SR, Farber C, Grinberg D, LaCroix AZ, Haessler J, Chasman DI, Giulianini F, Rose LM, Ridker PM, Eisman JA, Nguyen TV, Center JR, Nogues X, Garcia-Giralt N, Launer LL, Gudnason V, Mellström D, Vandenput L, Amin N, van Duijn CM, Karlsson MK, Ljunggren Ö, Svensson O, Hallmans G, Rousseau F, Giroux S, Bussière J, Arp PP, Koromani F, Prince RL, Lewis JR, Langdahl BL, Hermann AP, Jensen JE, Kaptoge S, Khaw KT, Reeve J, Formosa MM, Xuereb-Anastasi A, Åkesson K, McGuigan FE, Garg G, Olmos JM, Zarrabeitia MT, Riancho JA, Ralston SH, Alonso N, Jiang X, Goltzman D, Pastinen T, Grundberg E, Gauguier D, Orwoll ES, Karasik D, Davey-Smith G, AOGC Consortium, Smith AV, Siggeirsdottir K, Harris TB, Zillikens MC, van Meurs JB, Thorsteinsdottir U, Maurano MT, Timpson NJ, Soranzo N, Durbin R, Wilson SG, Ntzani EE, Brown MA, Stefansson K, Hinds DA, Spector T, Cupples LA, Ohlsson C, Greenwood CM, UK10K Consortium, Jackson RD, Rowe DW, Loomis CA, Evans DM, Ackert-Bicknell CL, Joyner AL, Duncan EL, Kiel DP, Rivadeneira F, Richards JB., Free PMC Article

Novel role of Engrailed 1 as a prosurvival transcription factor in basal-like breast cancer and engineering of interference peptides block its oncogenic function.
Beltran AS, Graves LM, Blancafort P., Free PMC Article

The lifelong maintenance of mesencephalic dopaminergic neurons by Nurr1 and engrailed.
Alavian KN, Jeddi S, Naghipour SI, Nabili P, Licznerski P, Tierney TS., Free PMC Article

Developmental transcription factor EN1--a novel biomarker in human salivary gland adenoid cystic carcinoma.
Bell D, Bell A, Roberts D, Weber RS, El-Naggar AK., Free PMC Article

A method of utrophin up-regulation through RNAi-mediated knockdown of the transcription factor EN1.
Wang Q, Cao DH, Jin CL, Lin CK, Ma HW, Wu YY.

[The regulation of UTROPHIN expression by EN1].
Wang Q, Cao DH, Lin CK, Wang ZD, Cui WT, Jin CL.

Association of transcription factor polymorphisms PITX3 and EN1 with Parkinson's disease.
Haubenberger D, Reinthaler E, Mueller JC, Pirker W, Katzenschlager R, Froehlich R, Bruecke T, Daniel G, Auff E, Zimprich A.

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article

Long-range epigenetic silencing at 2q14.2 affects most human colorectal cancers and may have application as a non-invasive biomarker of disease.
Mayor R, Casadomé L, Azuara D, Moreno V, Clark SJ, Capellà G, Peinado MA., Free PMC Article

Model-based gene selection shows engrailed 1 is associated with antipsychotic response.
Webb BT, Sullivan PF, Skelly T, van den Oord EJ.