| NCoR1 limits angiogenic capacity by altering Notch signaling. | NCoR1 limits angiogenic capacity by altering Notch signaling.
Teichmann T, Malacarne P, Zehr S, Günther S, Pflüger-Müller B, Warwick T, Brandes RP. | 03/6/2024 |
| The thyroid hormone enhances mouse embryonic fibroblasts reprogramming to pluripotent stem cells: role of the nuclear receptor corepressor 1. | The thyroid hormone enhances mouse embryonic fibroblasts reprogramming to pluripotent stem cells: role of the nuclear receptor corepressor 1.
Contreras-Jurado C, Montero-Pedrazuela A, Pérez RF, Alemany S, Fraga MF, Aranda A., Free PMC Article | 12/29/2023 |
| The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG. | The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG.
Kugler E, Madiwale S, Yong D, Thoms JAI, Birger Y, Sykes DB, Schmoellerl J, Drakul A, Priebe V, Yassin M, Aqaqe N, Rein A, Fishman H, Geron I, Chen CW, Raught B, Liu Q, Ogana H, Liedke E, Bourquin JP, Zuber J, Milyavsky M, Pimanda J, Privé GG, Izraeli S., Free PMC Article | 09/27/2023 |
| Chaperone-mediated autophagy dysregulation during aging impairs hepatic fatty acid oxidation via accumulation of NCoR1. | Chaperone-mediated autophagy dysregulation during aging impairs hepatic fatty acid oxidation via accumulation of NCoR1.
Choi YJ, Yun SH, Yu J, Mun Y, Lee W, Park CJ, Han BW, Lee BH., Free PMC Article | 09/11/2023 |
| p21-activated kinase 4 suppresses fatty acid beta-oxidation and ketogenesis by phosphorylating NCoR1. | p21-activated kinase 4 suppresses fatty acid β-oxidation and ketogenesis by phosphorylating NCoR1.
Shi MY, Yu HC, Han CY, Bang IH, Park HS, Jang KY, Lee S, Son JB, Kim ND, Park BH, Bae EJ., Free PMC Article | 08/22/2023 |
| Interaction between poly(A)-binding protein PABPC4 and nuclear receptor corepressor NCoR1 modulates a metabolic stress response. | Interaction between poly(A)-binding protein PABPC4 and nuclear receptor corepressor NCoR1 modulates a metabolic stress response.
Oliveira AG, Oliveira LD, Cruz MV, Guimarães DSPSF, Lima TI, Santos-Fávero BC, Luchessi AD, Pauletti BA, Leme AP, Bajgelman MC, Afonso J, Regitano LCA, Carvalho HF, Carneiro EM, Kobarg J, Perissi V, Auwerx J, Silveira LR., Free PMC Article | 06/28/2023 |
| NCoR1 controls immune tolerance in conventional dendritic cells by fine-tuning glycolysis and fatty acid oxidation. | NCoR1 controls immune tolerance in conventional dendritic cells by fine-tuning glycolysis and fatty acid oxidation.
Sen K, Pati R, Jha A, Mishra GP, Prusty S, Chaudhary S, Swetalika S, Podder S, Sen A, Swain M, Nanda RK, Raghav SK., Free PMC Article | 01/28/2023 |
| Ncor1 Deficiency Promotes Osteoclastogenesis and Exacerbates Periodontitis. | Ncor1 Deficiency Promotes Osteoclastogenesis and Exacerbates Periodontitis.
Ma XX, Meng XQ, Wang YL, Liu Y, Shi XR, Shao S, Duan SZ, Lu HX. | 12/31/2022 |
| Macrophage Nuclear Receptor Corepressor 1 Deficiency Protects Against Ischemic Stroke in Mice. | Macrophage Nuclear Receptor Corepressor 1 Deficiency Protects Against Ischemic Stroke in Mice.
Shao S, Chen YL, Du LJ, Liu Y, Zhu H, Zhou LJ, Liu T, Lin WZ, Yu F, Ma XX, Shi XR, Meng XQ, Liu Y, Wang YL, Bai L, Zhang XH, Jia F, Duan SZ. | 11/5/2022 |
| KLF7 Alleviates Atherosclerotic Lesions and Inhibits Glucose Metabolic Reprogramming in Macrophages by Regulating HDAC4/miR-148b-3p/NCOR1. | KLF7 Alleviates Atherosclerotic Lesions and Inhibits Glucose Metabolic Reprogramming in Macrophages by Regulating HDAC4/miR-148b-3p/NCOR1.
Chen F, Li J, Zheng T, Chen T, Yuan Z. | 10/29/2022 |
| SMRT and NCoR1 fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling. | SMRT and NCoR1 fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling.
Jha A, Ahad A, Mishra GP, Sen K, Smita S, Minz AP, Biswas VK, Tripathy A, Senapati S, Gupta B, Acha-Orbea H, Raghav SK., Free PMC Article | 10/22/2022 |
| The nuclear receptor co-repressor 1 is a novel cardioprotective factor against acute myocardial ischemia-reperfusion injury. | The nuclear receptor co-repressor 1 is a novel cardioprotective factor against acute myocardial ischemia-reperfusion injury.
Qin Z, Gao L, Lin G, Zhu H, Chen Y, Zhong F, Zhou H, Duan S, Pu J. | 04/30/2022 |
| Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis. | Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis.
Ritter MJ, Amano I, Imai N, Soares De Oliveira L, Vella KR, Hollenberg AN., Free PMC Article | 03/26/2022 |
| Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis. | Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis.
Matsumura Y, Ito R, Yajima A, Yamaguchi R, Tanaka T, Kawamura T, Magoori K, Abe Y, Uchida A, Yoneshiro T, Hirakawa H, Zhang J, Arai M, Yang C, Yang G, Takahashi H, Fujihashi H, Nakaki R, Yamamoto S, Ota S, Tsutsumi S, Inoue SI, Kimura H, Wada Y, Kodama T, Inagaki T, Osborne TF, Aburatani H, Node K, Sakai J., Free PMC Article | 01/8/2022 |
| A cell type-specific expression map of NCoR1 and SMRT transcriptional co-repressors in the mouse brain. | A cell type-specific expression map of NCoR1 and SMRT transcriptional co-repressors in the mouse brain.
Iemolo A, Montilla-Perez P, Lai IC, Meng Y, Nolan S, Wen J, Rusu I, Dulcis D, Telese F., Free PMC Article | 11/13/2021 |
| Macrophage NCOR1 protects from atherosclerosis by repressing a pro-atherogenic PPARgamma signature. | Macrophage NCOR1 protects from atherosclerosis by repressing a pro-atherogenic PPARγ signature.
Oppi S, Nusser-Stein S, Blyszczuk P, Wang X, Jomard A, Marzolla V, Yang K, Velagapudi S, Ward LJ, Yuan XM, Geiger MA, Guillaumon AT, Othman A, Hornemann T, Rancic Z, Ryu D, Oosterveer MH, Osto E, Lüscher TF, Stein S. | 06/12/2021 |
| NCoR1 Protects Mice From Dextran Sodium Sulfate-Induced Colitis by Guarding Colonic Crypt Cells From Luminal Insult. | NCoR1 Protects Mice From Dextran Sodium Sulfate-Induced Colitis by Guarding Colonic Crypt Cells From Luminal Insult.
Mennillo E, Yang X, Paszek M, Auwerx J, Benner C, Chen S., Free PMC Article | 05/15/2021 |
| NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4(+) T Cells. | NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4(+) T Cells.
Hainberger D, Stolz V, Zhu C, Schuster M, Müller L, Hamminger P, Rica R, Waltenberger D, Alteneder M, Krausgruber T, Hladik A, Knapp S, Bock C, Trauner M, Farrar MA, Ellmeier W., Free PMC Article | 03/27/2021 |
| Macrophage NCOR1 Deficiency Ameliorates Myocardial Infarction and Neointimal Hyperplasia in Mice. | Macrophage NCOR1 Deficiency Ameliorates Myocardial Infarction and Neointimal Hyperplasia in Mice.
Du LJ, Sun JY, Zhang WC, Wang YL, Zhu H, Liu T, Gao MZ, Zheng C, Zhang YY, Liu Y, Liu Y, Shao S, Zhang XQ, Leng Q, Auwerx J, Duan SZ., Free PMC Article | 03/13/2021 |
| NCoR1 fine-tunes type-I IFN response in cDC1 dendritic cells by directly regulating Myd88-IRF7 axis under TLR9. | NCoR1 fine-tunes type-I IFN response in cDC1 dendritic cells by directly regulating Myd88-IRF7 axis under TLR9.
Ahad A, Smita S, Mishra GP, Biswas VK, Sen K, Gupta B, Garcin D, Acha-Orbea H, Raghav SK. | 02/2/2021 |
| Specific ablation of the NCoR corepressor delta splice variant reveals alternative RNA splicing as a key regulator of hepatic metabolism. | Specific ablation of the NCoR corepressor δ splice variant reveals alternative RNA splicing as a key regulator of hepatic metabolism.
Goodson ML, Knotts TA, Campbell EL, Snyder CA, Young BM, Privalsky ML., Free PMC Article | 12/19/2020 |
| the transcriptional coregulators, PGC-1alpha and NCoR1, are essential mediators of mitochondrial redox homeostasis in skeletal muscle cells | Opposing action of NCoR1 and PGC-1α in mitochondrial redox homeostasis.
Lima TI, Guimarães DSPSF, Oliveira AG, Araujo H, Sponton CHG, Souza-Pinto NC, Saito Â, Figueira ACM, Palameta S, Bajgelman MC, Calixto A, Pinto S, Mori MA, Orofino J, Perissi V, Mottis A, Auwerx J, Silveira LR. | 08/12/2020 |
| RNF20 promoted proteasomal degradation of nuclear corepressor 1 (NCoR1), which led to stimulation of the transcriptional activity of PPARgamma. Collectively, these data suggest that RNF20-NCoR1 is a novel axis in adipocyte biology through fine-tuning the transcriptional activity of PPARgamma. | RNF20 Functions as a Transcriptional Coactivator for PPARγ by Promoting NCoR1 Degradation in Adipocytes.
Jeon YG, Lee JH, Ji Y, Sohn JH, Lee D, Kim DW, Yoon SG, Shin KC, Park J, Seong JK, Cho JY, Choe SS, Kim JB. | 07/11/2020 |
| Here, the authors found that cardiomyocyte-specific NCoR1 knockout mice manifested cardiac hypertrophy at baseline and had more severe cardiac hypertrophy and dysfunction after pressure overload. | Nuclear receptor corepressor 1 represses cardiac hypertrophy.
Li C, Sun XN, Chen BY, Zeng MR, Du LJ, Liu T, Gu HH, Liu Y, Li YL, Zhou LJ, Zheng XJ, Zhang YY, Zhang WC, Liu Y, Shi C, Shao S, Shi XR, Yi Y, Liu X, Wang J, Auwerx J, Wang ZV, Jia F, Li RG, Duan SZ., Free PMC Article | 05/2/2020 |
| NCoR1-deficient hematopoietic stem cell exhibited normal self-renewal capacity but severely impaired lymphoid-differentiation potential in competitive hematopoietic-reconstitution assays. | The nuclear receptor corepressor NCoR1 regulates hematopoiesis and leukemogenesis in vivo.
Wan X, Liu L, Zhou P, Hui X, He Q, Yu F, Zhang W, Ding X, Yuan X, Zhang N, Zhao Y, Zhu R, Liu Y, Hao P, Auwerx J, Song X, Leng Q, Zhang Y., Free PMC Article | 03/7/2020 |