FCRL3 expression is upregulated and closely correlates with TIGIT expression in regulatory T cells of patients with systemic lupus erythematosus. | FCRL3 expression is upregulated and closely correlates with TIGIT expression in regulatory T cells of patients with systemic lupus erythematosus. Bahabayi A, Zhang YH, Yuan Z, Wang Y, Zhang Z, Zeng X, Guan Z, Wang P, Liu C. | 05/28/2024 |
Ectopic Expression of TIGIT in Lung Adenocarcinoma and Its Clinical Significance. | Ectopic Expression of TIGIT in Lung Adenocarcinoma and Its Clinical Significance. He S, Qian N, Ren S, Ma C, Shen D, Tian Y. | 03/7/2024 |
LAG3 and TIGIT Expression on Tumor-Infiltrating Lymphocytes in Cutaneous Melanoma. | LAG3 and TIGIT Expression on Tumor-Infiltrating Lymphocytes in Cutaneous Melanoma. Naimy S, Bzorek M, Eriksen JO, Løvendorf MB, Litman T, Dyring-Andersen B, Gjerdrum LMR. | 02/16/2024 |
The immune checkpoint TIGIT/CD155 promotes the exhaustion of CD8 + T cells in TNBC through glucose metabolic reprogramming mediated by PI3K/AKT/mTOR signaling. | The immune checkpoint TIGIT/CD155 promotes the exhaustion of CD8 + T cells in TNBC through glucose metabolic reprogramming mediated by PI3K/AKT/mTOR signaling. Huang M, Yu X, Wang Q, Jiang Z, Li X, Chen W, Song C., Free PMC Article | 01/27/2024 |
Decreased expression of TIGIT on CD14 + monocytes correlates with clinical features and laboratory parameters of patients with primary Sjogren's syndrome. | Decreased expression of TIGIT on CD14 + monocytes correlates with clinical features and laboratory parameters of patients with primary Sjögren's syndrome. Zhao P, Peng C, Chang X, Cheng W, Yang Y, Shen Y, Sun C, Feng X, Liu C, Wu J. | 01/11/2024 |
[Expression and effect of TIGIT in peripheral blood CD56[+] T cells of patients with rheumatoid arthritis]. | [Expression and effect of TIGIT in peripheral blood CD56(+) T cells of patients with rheumatoid arthritis]. Zhu X, Li X, Liu X, Shan Y, Li S, Shen X. | 11/22/2023 |
IL-21 collaborates with anti-TIGIT to restore NK cell function in chronic HBV infection. | IL-21 collaborates with anti-TIGIT to restore NK cell function in chronic HBV infection. Tang L, Li Q, Chen L, Li X, Gu S, He W, Pan Q, Wang L, Sun J, Yi X, Li Y. | 11/2/2023 |
CD155 and Its Receptors as Targets for Cancer Therapy. | CD155 and Its Receptors as Targets for Cancer Therapy. Paolini R, Molfetta R., Free PMC Article | 08/31/2023 |
TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation. | TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation. Worboys JD, Vowell KN, Hare RK, Ambrose AR, Bertuzzi M, Conner MA, Patel FP, Zammit WH, Gali-Moya J, Hazime KS, Jones KL, Rey C, Jonjic S, Rovis TL, Tannahill GM, Cruz De Matos GDS, Waight JD, Davis DM., Free PMC Article | 08/25/2023 |
[Application of TIGIT combined with interleukin-6 detection in the evaluation of Crohn's disease status]. | [Application of TIGIT combined with interleukin-6 detection in the evaluation of Crohn's disease status]. Xiao L, Yang JP, Wang W. | 08/19/2023 |
Clinical significance of the expression of FOXP3 and TIGIT in Merkel cell carcinoma. | Clinical significance of the expression of FOXP3 and TIGIT in Merkel cell carcinoma. Iwasaki T, Hayashi K, Matsushita M, Nonaka D, Matsumoto T, Taniguchi M, Kuwamoto S, Umekita Y, Oda Y., Free PMC Article | 08/14/2023 |
The immunomodulatory molecule TIGIT is expressed by chronic lymphocytic leukemia cells and contributes to anergy. | The immunomodulatory molecule TIGIT is expressed by chronic lymphocytic leukemia cells and contributes to anergy. Arruga F, Rubin M, Papazoglou D, Iannello A, Ioannou N, Moia R, Rossi D, Gaidano G, Coscia M, Laurenti L, D'Arena G, Allan JN, Furman RR, Vaisitti T, Ramsay AG, Deaglio S., Free PMC Article | 08/2/2023 |
TIGIT, a novel immune checkpoint therapy for melanoma. | TIGIT, a novel immune checkpoint therapy for melanoma. Tang W, Chen J, Ji T, Cong X., Free PMC Article | 07/31/2023 |
TIGIT immune checkpoint blockade enhances immunity of human peripheral blood NK cells against castration-resistant prostate cancer. | TIGIT immune checkpoint blockade enhances immunity of human peripheral blood NK cells against castration-resistant prostate cancer. Wang F, Liu S, Liu F, Xu T, Ma J, Liang J, Wang J, Liu D, Yang F, Li J, Xing N. | 07/24/2023 |
Expression of Inhibitory Receptors TIGIT, TIM-3, and LAG-3 on CD4+ T Cells from Patients with Different Clinical Forms of Chronic Chagas Disease. | Expression of Inhibitory Receptors TIGIT, TIM-3, and LAG-3 on CD4+ T Cells from Patients with Different Clinical Forms of Chronic Chagas Disease. Ferragut F, Alcaraz PB, Beati P, Girard MC, Ossowski MS, Chadi R, Fernández M, Hernández-Vásquez Y, Acevedo GR, Gómez KA. | 03/11/2023 |
NKG2D engagement on human NK cells leads to DNAM-1 hypo-responsiveness through different converging mechanisms. | NKG2D engagement on human NK cells leads to DNAM-1 hypo-responsiveness through different converging mechanisms. Milito ND, Zingoni A, Stabile H, Soriani A, Capuano C, Cippitelli M, Gismondi A, Santoni A, Paolini R, Molfetta R. | 02/14/2023 |
CD155 mutation (Ala67Thr) increases the binding affinity for and the signaling via an inhibitory immunoreceptor TIGIT. | CD155 mutation (Ala67Thr) increases the binding affinity for and the signaling via an inhibitory immunoreceptor TIGIT. Matsuo T, Iguchi-Manaka A, Shibuya A, Shibuya K., Free PMC Article | 11/12/2022 |
Impaired TIGIT expression on B cells drives circulating follicular helper T cell expansion in multiple sclerosis. | Impaired TIGIT expression on B cells drives circulating follicular helper T cell expansion in multiple sclerosis. Asashima H, Axisa PP, Pham THG, Longbrake EE, Ruff WE, Lele N, Cohen I, Raddassi K, Sumida TS, Hafler DA., Free PMC Article | 10/22/2022 |
Prognostic value of TIGIT in East Asian patients with solid cancers: A systematic review, meta-analysis and pancancer analysis. | Prognostic value of TIGIT in East Asian patients with solid cancers: A systematic review, meta-analysis and pancancer analysis. Li S, Li L, Pan T, Li X, Tong Y, Jin Y., Free PMC Article | 10/22/2022 |
TIGIT is the central player in T-cell suppression associated with CAR T-cell relapse in mantle cell lymphoma. | TIGIT is the central player in T-cell suppression associated with CAR T-cell relapse in mantle cell lymphoma. Jiang VC, Hao D, Jain P, Li Y, Cai Q, Yao Y, Nie L, Liu Y, Jin J, Wang W, Lee HH, Che Y, Dai E, Han G, Wang R, Rai K, Futreal A, Flowers C, Wang L, Wang M., Free PMC Article | 10/8/2022 |
Increased frequency of TIGIT+ CD4 T Cell subset in autoantibody-positive first-degree relatives of patients with rheumatoid arthritis. | Increased frequency of TIGIT+ CD4 T Cell subset in autoantibody-positive first-degree relatives of patients with rheumatoid arthritis. Anaparti V, Tanner S, Zhang C, O'Neil L, Smolik I, Meng X, Marshall AJ, El-Gabalawy H., Free PMC Article | 09/3/2022 |
Expression of T-cell immunoreceptor with immunoglobulin and tyrosine-based inhibitory motif domains (TIGIT) in anaplastic thyroid carcinoma. | Expression of T-cell immunoreceptor with immunoglobulin and tyrosine-based inhibitory motif domains (TIGIT) in anaplastic thyroid carcinoma. Nakazawa T, Nagasaka T, Yoshida K, Hasegawa A, Guo F, Wu D, Hiroshima K, Katoh R., Free PMC Article | 08/27/2022 |
Sequential Single-Cell Transcriptional and Protein Marker Profiling Reveals TIGIT as a Marker of CD19 CAR-T Cell Dysfunction in Patients with Non-Hodgkin Lymphoma. | Sequential Single-Cell Transcriptional and Protein Marker Profiling Reveals TIGIT as a Marker of CD19 CAR-T Cell Dysfunction in Patients with Non-Hodgkin Lymphoma. Jackson Z, Hong C, Schauner R, Dropulic B, Caimi PF, de Lima M, Giraudo MF, Gupta K, Reese JS, Hwang TH, Wald DN., Free PMC Article | 08/13/2022 |
CD155/TIGIT signalling plays a vital role in the regulation of bone marrow mesenchymal stem cell-induced natural killer-cell exhaustion in multiple myeloma. | CD155/TIGIT signalling plays a vital role in the regulation of bone marrow mesenchymal stem cell-induced natural killer-cell exhaustion in multiple myeloma. Liu ZY, Deng L, Jia Y, Liu H, Ding K, Wang W, Zhang H, Fu R., Free PMC Article | 07/30/2022 |
The CD226/TIGIT axis is involved in T cell hypo-responsiveness appearance in long-term kidney transplant recipients. | The CD226/TIGIT axis is involved in T cell hypo-responsiveness appearance in long-term kidney transplant recipients. Del Bello A, Gouin A, Chaubet C, Kamar N, Treiner E., Free PMC Article | 07/23/2022 |