PPP3CB overexpression mediates EGFR TKI resistance in lung tumors via calcineurin/MEK/ERK signaling. | PPP3CB overexpression mediates EGFR TKI resistance in lung tumors via calcineurin/MEK/ERK signaling. Gazzeri S, Zubchuk N, Montaudon E, Nemati F, Huot-Marchand S, Berardi G, Pucciarelli A, Dib Y, Nerini D, Oddou C, Pezet M, David-Boudet L, Ardin C, de Fraipont F, Maraver A, Girard N, Decaudin D, Toffart AC, Eymin B., Free PMC Article | 10/8/2024 |
The oncogenic ADAMTS1-VCAN-EGFR cyclic axis drives anoikis resistance and invasion in renal cell carcinoma. | The oncogenic ADAMTS1-VCAN-EGFR cyclic axis drives anoikis resistance and invasion in renal cell carcinoma. Wen YC, Lin YW, Ho KH, Yang YC, Lai FR, Chu CY, Chen JQ, Lee WJ, Chien MH., Free PMC Article | 10/7/2024 |
Structural insights into the role and targeting of EGFRvIII. | Structural insights into the role and targeting of EGFRvIII. Bagchi A, Stayrook SE, Xenaki KT, Starbird CA, Doulkeridou S, El Khoulati R, Roovers RC, Schmitz KR, van Bergen En Henegouwen PMP, Ferguson KM., | 09/16/2024 |
A Comparison of Immunohistochemical Expression of Epidermal Growth Factor Receptor and Human Epidermal Growth Factor Receptor 2 in Dental Follicles with Different Radiographic Sizes. | A Comparison of Immunohistochemical Expression of Epidermal Growth Factor Receptor and Human Epidermal Growth Factor Receptor 2 in Dental Follicles with Different Radiographic Sizes. Saravani S, Nemati Rezvani H, Shahraki M, Kadeh H., Free PMC Article | 09/11/2024 |
Immunohistochemical Expression of Caspase1 and Epidermal Growth Factor Receptor in Invasive Breast Carcinoma and Their Biological and Prognostic Associations. | Immunohistochemical Expression of Caspase1 and Epidermal Growth Factor Receptor in Invasive Breast Carcinoma and Their Biological and Prognostic Associations. Enan ET, Abd El Hafez A, Hussin E, Hany HSEDI. | 09/6/2024 |
The physical basis of analog-to-digital signal processing in the EGFR system-Delving into the role of the endoplasmic reticulum. | The physical basis of analog-to-digital signal processing in the EGFR system-Delving into the role of the endoplasmic reticulum. Kreplin LZ, Arumugam S. | 09/4/2024 |
Multispectral fluorescence imaging of EGFR and PD-L1 for precision detection of oral squamous cell carcinoma: a preclinical and clinical study. | Multispectral fluorescence imaging of EGFR and PD-L1 for precision detection of oral squamous cell carcinoma: a preclinical and clinical study. Jin N, An Y, Tian Y, Zhang Z, He K, Chi C, Mu W, Tian J, Du Y., Free PMC Article | 08/30/2024 |
Primary versus acquired epidermal growth factor receptor Thr790Met mutant non-small cell lung cancer: clinical features and prognoses. | Primary versus acquired epidermal growth factor receptor Thr790Met mutant non-small cell lung cancer: clinical features and prognoses. Zhou S, Cai G, Meng X, Li M, Fu Y, Wang X, Wang K, Han X. | 08/30/2024 |
Ethnicity-Based Variations in Focal Adhesion Kinase Signaling in Glioblastoma Gene Expression: A Study of the Puerto Rican Hispanic Population. | Ethnicity-Based Variations in Focal Adhesion Kinase Signaling in Glioblastoma Gene Expression: A Study of the Puerto Rican Hispanic Population. Porter T, Del Valle MM, Kucheryavykh L., Free PMC Article | 08/28/2024 |
EGFR mutations and abnormal trafficking in cancers. | EGFR mutations and abnormal trafficking in cancers. Kang X, Li R, Li X, Xu X. | 08/26/2024 |
EGFR mutations induce the suppression of CD8[+] T cell and anti-PD-1 resistance via ERK1/2-p90RSK-TGF-beta axis in non-small cell lung cancer. | EGFR mutations induce the suppression of CD8(+) T cell and anti-PD-1 resistance via ERK1/2-p90RSK-TGF-β axis in non-small cell lung cancer. Huang H, Zhu X, Yu Y, Li Z, Yang Y, Xia L, Lu S., Free PMC Article | 08/12/2024 |
SNX32 Regulates Sorting and Trafficking of Activated EGFR to the Lysosomal Degradation Pathway. | SNX32 Regulates Sorting and Trafficking of Activated EGFR to the Lysosomal Degradation Pathway. Wang D, Zhao X, Wang P, Liu JJ. | 07/31/2024 |
ALDOA coordinates PDE3A through the beta-catenin/ID3 axis to stimulate cancer metastasis and M2 polarization in lung cancer with EGFR mutations. | ALDOA coordinates PDE3A through the β-catenin/ID3 axis to stimulate cancer metastasis and M2 polarization in lung cancer with EGFR mutations. Yeh CY, Cai HY, Kuo HH, Lin YY, He ZJ, Cheng HC, Yang CJ, Huang CF, Chang YC. | 06/26/2024 |
SNX16 is required for hepatocellular carcinoma survival via modulating the EGFR-AKT signaling pathway. | SNX16 is required for hepatocellular carcinoma survival via modulating the EGFR-AKT signaling pathway. Yuan L, Meng Y, Xiang J., Free PMC Article | 06/17/2024 |
GLUT1 promotes cell proliferation via binds and stabilizes phosphorylated EGFR in lung adenocarcinoma. | GLUT1 promotes cell proliferation via binds and stabilizes phosphorylated EGFR in lung adenocarcinoma. Zhou Z, Li Y, Chen S, Xie Z, Du Y, Liu Y, Shi Y, Lin X, Zeng X, Zhao H, Chen G., Free PMC Article | 06/11/2024 |
PTPN23[Thr] variant reduces susceptibility and tumorigenesis in esophageal squamous cell carcinoma through dephosphorylation of EGFR. | PTPN23[Thr] variant reduces susceptibility and tumorigenesis in esophageal squamous cell carcinoma through dephosphorylation of EGFR. Niu S, Ma J, Li Y, Yue X, Shi K, Pan M, Song L, Tan Y, Gu L, Liu S, Chang J. | 06/8/2024 |
Uncommon de novo EGFR[T790M]-Mutant NSCLC characterized with unique genetic Features: Clinical response and acquired resistance to the third-generation EGFR-TKIs treatment. | Uncommon de novo EGFR(T790M)-Mutant NSCLC characterized with unique genetic Features: Clinical response and acquired resistance to the third-generation EGFR-TKIs treatment. Pang LL, Zhuang WT, Huang YH, Liao J, Li MZ, Lv Y, Zhang L, Fang WF. | 05/14/2024 |
TGFbeta overcomes FGF-induced transinhibition of EGFR in lens cells to enable fibrotic secondary cataract. | TGFβ overcomes FGF-induced transinhibition of EGFR in lens cells to enable fibrotic secondary cataract. VanSlyke JK, Boswell BA, Musil LS., Free PMC Article | 05/9/2024 |
Nasopharyngeal carcinoma with non-squamous phenotype may be a variant of nasopharyngeal squamous cell carcinoma after inhibition of EGFR/PI3K/AKT/mTOR pathway. | Nasopharyngeal carcinoma with non-squamous phenotype may be a variant of nasopharyngeal squamous cell carcinoma after inhibition of EGFR/PI3K/AKT/mTOR pathway. Wang J, Shang Y, Wang Y, Li Y, Wang L, Huang S, Lyu X. | 05/7/2024 |
PDZK1 suppresses TNBC development and sensitizes TNBC cells to erlotinib via the EGFR pathway. | PDZK1 suppresses TNBC development and sensitizes TNBC cells to erlotinib via the EGFR pathway. Ma Y, Fang Z, Zhang H, Qi Y, Mao Y, Zheng J., Free PMC Article | 04/30/2024 |
Allelic Context of EGFR C797X-Mutant Lung Cancer Defines Four Subtypes With Heterogeneous Genomic Landscape and Distinct Clinical Outcomes. | Allelic Context of EGFR C797X-Mutant Lung Cancer Defines Four Subtypes With Heterogeneous Genomic Landscape and Distinct Clinical Outcomes. Lu C, Wei XW, Wang Z, Zhou Z, Liu YT, Zheng D, He Y, Xie ZH, Li Y, Zhang Y, Zhang YC, Huang ZJ, Mei SQ, Liu JQ, Guan XH, Deng Y, Chen ZH, Tu HY, Xu CR, Chen HJ, Zhong WZ, Yang JJ, Zhang XC, Mok TSK, Wu YL, Zhou Q. | 04/18/2024 |
Extracellular domain mutations of the EGF receptor differentially modulate high-affinity and low-affinity responses to EGF receptor ligands. | Extracellular domain mutations of the EGF receptor differentially modulate high-affinity and low-affinity responses to EGF receptor ligands. Macdonald-Obermann JL, Pike LJ., Free PMC Article | 04/16/2024 |
The impact of EGFR T790M mutation status following the development of Osimertinib resistance on the efficacy of Osimertinib in non-small cell lung cancer: A meta-analysis. | The impact of EGFR T790M mutation status following the development of Osimertinib resistance on the efficacy of Osimertinib in non-small cell lung cancer: A meta-analysis. Guo L, Zhou G, Huang M, Tang K, Xu J, Chen J., Free PMC Article | 04/12/2024 |
VGLL1 stabilization of cytoplasmic TAZ promotes EGFR expression and maintains tumor initiating cells in breast cancer independent of TEAD. | VGLL1 stabilization of cytoplasmic TAZ promotes EGFR expression and maintains tumor initiating cells in breast cancer independent of TEAD. Parimita S, Das A, Samanta S. | 04/12/2024 |
Influence of EGFR mutation status and PD-L1 expression in stage III unresectable non-small cell lung cancer treated with chemoradiation and consolidation durvalumab. | Influence of EGFR mutation status and PD-L1 expression in stage III unresectable non-small cell lung cancer treated with chemoradiation and consolidation durvalumab. Nindra U, Shahnam A, Stevens S, Pal A, Nagrial A, Lee J, Yip PY, Adam T, Boyer M, Kao S, Bray V. | 03/29/2024 |