| Ephrin B3 exacerbates colitis and colitis-associated colorectal cancer. | Ephrin B3 exacerbates colitis and colitis-associated colorectal cancer.
Qiao Z, Liao M, Xiao M, Luo S, Wang K, Niu M, Jiang H, Sun S, Xu G, Xu N, Xu Q, Liu Y. | 02/1/2024 |
| Blood vessels guide Schwann cell migration in the adult demyelinated CNS through Eph/ephrin signaling. | Blood vessels guide Schwann cell migration in the adult demyelinated CNS through Eph/ephrin signaling.
Garcia-Diaz B, Bachelin C, Coulpier F, Gerschenfeld G, Deboux C, Zujovic V, Charnay P, Topilko P, Baron-Van Evercooren A., Free PMC Article | 08/13/2020 |
| Analysis of the association of EPHB6, EFNB1 and EFNB3 variants with hypertension risks in males with hypogonadism. | Analysis of the association of EPHB6, EFNB1 and EFNB3 variants with hypertension risks in males with hypogonadism.
Wu T, Zhang BQ, Raelson J, Yao YM, Wu HD, Xu ZX, Marois-Blanchet FC, Tahir MR, Wang Y, Bradley WE, Luo H, Wu J, Sheng JZ, Hu SJ., Free PMC Article | 10/26/2019 |
| identified secretory and cell associated proteoglycans with high ability to bind ephrin-B3 and suggest that ephrin-B3 can bind to a protein complex organized by a membrane associated PG. | Ephrin-B3 binds both cell-associated and secreted proteoglycans.
Prydz K, Halstensen TS, Holen HL, Aasheim HC. | 01/19/2019 |
| The study provides evidence from single nucleotide polymorphism analyses of ADVANCE study demonstrating that EFNB3 is a hypertension risk gene. | Evidence from single nucleotide polymorphism analyses of ADVANCE study demonstrates EFNB3 as a hypertension risk gene.
Tremblay J, Wang Y, Raelson J, Marois-Blanchet FC, Wu Z, Luo H, Bradley E, Chalmers J, Woodward M, Harrap S, Hamet P, Wu J., Free PMC Article | 12/1/2018 |
| Data suggest that molecules in the erythropoietin-producing hepatocellular receptor B family (EPHB) / ephrinB (EFNB) signalling pathways, specifically ephrin B3 and GRIP1, are involved blood pressure regulation. | The role of GRIP1 and ephrin B3 in blood pressure control and vascular smooth muscle cell contractility.
Wang Y, Wu Z, Luo H, Peng J, Raelson J, Ehret GB, Munroe PB, Stoyanova E, Qin Z, Cloutier G, Bradley WE, Wu T, Shen JZ, Hu S, Wu J., Free PMC Article | 07/21/2018 |
| Data show that Ephrin B3 was concomitantly expressed with EphA2 and Ephrin A1 with higher Ephrin B3 levels found in non-squamous than in squamous tumors. | Ephrin B3 interacts with multiple EphA receptors and drives migration and invasion in non-small cell lung cancer.
Efazat G, Novak M, Kaminskyy VO, De Petris L, Kanter L, Juntti T, Bergman P, Zhivotovsky B, Lewensohn R, Hååg P, Viktorsson K., Free PMC Article | 02/10/2018 |
| Study found up-regulated expression of ephrinB3/EphB3 in intractable temporal lobe epilepsy patients and experimental temporal lobe epilepsy rats, which suggested that ephrinB3/EphB3 might be involved in the pathogenesis of temporal lobe epilepsy | Up-regulated ephrinB3/EphB3 expression in intractable temporal lobe epilepsy patients and pilocarpine induced experimental epilepsy rat model.
Huang H, Li R, Yuan J, Zhou X, Liu X, Ou S, Xu T, Chen Y. | 07/8/2017 |
| Findings suggest that EphrinB3 may be a relevant target for promoting remyelination in demyelinating disease | Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.
Syed YA, Zhao C, Mahad D, Möbius W, Altmann F, Foss F, González GA, Sentürk A, Acker-Palmer A, Lubec G, Lilley K, Franklin RJM, Nave KA, Kotter MRN., Free PMC Article | 10/22/2016 |
| Data suggest that fusion of Nipah viruses with host cells is facilitated by two of viral membrane proteins, the G protein and the F protein; G head domain binds to human ephrins B2 and B3 altering conformational density of entire G head domain. | Discerning intersecting fusion-activation pathways in the Nipah virus using machine learning.
Varma S, Botlani M, Leighty RE. | 07/25/2015 |
| Ephrin-B3 binds to B lymphocytes, most likely via a non-classical receptor, and induces migration of the memory B cell subpopulation. | Ephrin-B3 binds specifically to B lymphocytes in blood and induces migration.
Holen HL, Zernichow L, Fjelland KE, Evenroed IM, Tveit H, Aasheim HC. | 09/10/2011 |
| Phosphoproteomic profiling of nonsmall cell lung cancer cells reveals that ephrin B3 regulates pro-survival signaling through Akt1-mediated phosphorylation of the EphA2 receptor. | Phosphoproteomic profiling of NSCLC cells reveals that ephrin B3 regulates pro-survival signaling through Akt1-mediated phosphorylation of the EphA2 receptor.
Ståhl S, Branca RM, Efazat G, Ruzzene M, Zhivotovsky B, Lewensohn R, Viktorsson K, Lehtiö J. | 09/10/2011 |
| evidence for an unknown ephrin-B3-binding cell-surface proteoglycan involved in cellular signalling | Ephrin-B3 binds to a sulfated cell-surface receptor.
Holen HL, Zernichow L, Fjelland KE, Evenroed IM, Prydz K, Tveit H, Aasheim HC. | 02/26/2011 |
| Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.
Shen M, Vermeulen R, Rajaraman P, Menashe I, He X, Chapman RS, Yeager M, Thomas G, Burdett L, Hutchinson A, Yuenger J, Chanock S, Lan Q., Free PMC Article | 04/7/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesAssociation of polymorphisms in the SLIT2 axonal guidance gene with anger in suicide attempters.
Sokolowski M, Wasserman J, Wasserman D. Genetic susceptibility to distinct bladder cancer subphenotypes.
Guey LT, García-Closas M, Murta-Nascimento C, Lloreta J, Palencia L, Kogevinas M, Rothman N, Vellalta G, Calle ML, Marenne G, Tardón A, Carrato A, García-Closas R, Serra C, Silverman DT, Chanock S, Real FX, Malats N, EPICURO/Spanish Bladder Cancer Study investigators. Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.
Hosgood HD 3rd, Menashe I, Shen M, Yeager M, Yuenger J, Rajaraman P, He X, Chatterjee N, Caporaso NE, Zhu Y, Chanock SJ, Zheng T, Lan Q. | 09/24/2008 |
| report the crystal structures of the NiV-G both in its receptor-unbound state and in complex with ephrin-B3, providing, to our knowledge, the first view of a paramyxovirus attachment complex in which a cellular protein is used as the virus receptor | Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3.
Xu K, Rajashankar KR, Chan YP, Himanen JP, Broder CC, Nikolov DB., Free PMC Article | 01/21/2010 |
| Transgenic EphB1 and ephrin-B3 cooperatively regulate the proliferation and migration of neural progenitors in the hippocampus | EphB receptors regulate stem/progenitor cell proliferation, migration, and polarity during hippocampal neurogenesis.
Chumley MJ, Catchpole T, Silvany RE, Kernie SG, Henkemeyer M., Free PMC Article | 01/21/2010 |
| Immunohistochemistry shows robust staining for phosphorylated ephrin-B and ephrin-B3 in invading glioblastoma cells. | Ephrin-B3 ligand promotes glioma invasion through activation of Rac1.
Nakada M, Drake KL, Nakada S, Niska JA, Berens ME. | 01/21/2010 |
| expressed differentially in colon carcinoma and normal mucosa specimens and may play a role in progression of colon carcinoma | Coexpression of ephrin-Bs and their receptors in colon carcinoma.
Liu W, Ahmad SA, Jung YD, Reinmuth N, Fan F, Bucana CD, Ellis LM. | 01/21/2010 |
| EphrinB3 is a bona fide alternate receptor for NiV entry, and two residues in the G-H loop of the ephrin B-class ligands are critical determinants of NiV receptor activity. | Two key residues in ephrinB3 are critical for its use as an alternative receptor for Nipah virus.
Negrete OA, Wolf MC, Aguilar HC, Enterlein S, Wang W, Mühlberger E, Su SV, Bertolotti-Ciarlet A, Flick R, Lee B., Free PMC Article | 01/21/2010 |