| Recruitment of PVT1 Enhances YTHDC1-Mediated m6A Modification of IL-33 in Hyperoxia-Induced Lung Injury During Bronchopulmonary Dysplasia. | Recruitment of PVT1 Enhances YTHDC1-Mediated m6A Modification of IL-33 in Hyperoxia-Induced Lung Injury During Bronchopulmonary Dysplasia.
Bao T, Liu X, Hu J, Ma M, Li J, Cao L, Yu B, Cheng H, Zhao S, Tian Z., Free PMC Article | 05/31/2024 |
| Small hairpin inhibitory RNA delivery in the metanephric organ culture identifies long noncoding RNA Pvt1 as a modulator of cyst growth. | Small hairpin inhibitory RNA delivery in the metanephric organ culture identifies long noncoding RNA Pvt1 as a modulator of cyst growth.
Eckberg K, Weisser I, Buttram D, Somia N, Igarashi P, Aboudehen KS., Free PMC Article | 09/3/2022 |
| Long Non-coding RNA PVT1 Inhibits miR-30c-5p to Upregulate Rock2 to Modulate Cerebral Ischemia/Reperfusion Injury Through MAPK Signaling Pathway Activation. | Long Non-coding RNA PVT1 Inhibits miR-30c-5p to Upregulate Rock2 to Modulate Cerebral Ischemia/Reperfusion Injury Through MAPK Signaling Pathway Activation.
Zhang H, Li M, Liang J, Li M, Sun X. | 03/26/2022 |
| Circular RNA PVT1 silencing prevents ischemia-reperfusion injury in rat by targeting microRNA-125b and microRNA-200a. | Circular RNA PVT1 silencing prevents ischemia-reperfusion injury in rat by targeting microRNA-125b and microRNA-200a.
Luo C, Ling GX, Lei BF, Feng X, Xie XY, Fang C, Li YG, Cai XW, Zheng BS. | 02/12/2022 |
| Knockdown of lncRNA PVT1 attenuated macrophage M1 polarization and relieved sepsis induced myocardial injury via miR-29a/HMGB1 axis. | Knockdown of lncRNA PVT1 attenuated macrophage M1 polarization and relieved sepsis induced myocardial injury via miR-29a/HMGB1 axis.
Luo YY, Yang ZQ, Lin XF, Zhao FL, Tu HT, Wang LJ, Wen MY, Xian SX. | 01/22/2022 |
| ZFP36L2 regulates myocardial ischemia/reperfusion injury and attenuates mitochondrial fusion and fission by LncRNA PVT1. | ZFP36L2 regulates myocardial ischemia/reperfusion injury and attenuates mitochondrial fusion and fission by LncRNA PVT1.
Wu F, Huang W, Tan Q, Guo Y, Cao Y, Shang J, Ping F, Wang W, Li Y., Free PMC Article | 11/6/2021 |
| N(6) -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness. | N(6) -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness.
Lee J, Wu Y, Harada BT, Li Y, Zhao J, He C, Ma Y, Wu X., Free PMC Article | 10/23/2021 |
| LncPVT1 promotes cartilage degradation in diabetic OA mice by downregulating miR-146a and activating TGF-beta/SMAD4 signaling. | LncPVT1 promotes cartilage degradation in diabetic OA mice by downregulating miR-146a and activating TGF-β/SMAD4 signaling.
Wang YZ, Yao-Li, Liang SK, Ding LB, Feng-Li, Guan J, Wang HJ. | 07/24/2021 |
| lncRNA PVT1 modulates NLRP3mediated pyroptosis in septic acute kidney injury by targeting miR20a5p. | lncRNA PVT1 modulates NLRP3‑mediated pyroptosis in septic acute kidney injury by targeting miR‑20a‑5p.
Deng LT, Wang QL, Yu C, Gao M. | 05/15/2021 |
| Upregulated lncRNA Pvt1 may be important for cardiac remodeling at the infarct border zone. | Upregulated lncRNA Pvt1 may be important for cardiac remodeling at the infarct border zone.
Liu B, Cheng Y, Tian J, Zhang L, Cui X., Free PMC Article | 05/1/2021 |
| The findings demonstrate that Pvt1b acts at the intersection of the p53 and Myc transcriptional networks to reinforce the anti-proliferative activities of p53. | p53 Activates the Long Noncoding RNA Pvt1b to Inhibit Myc and Suppress Tumorigenesis.
Olivero CE, Martínez-Terroba E, Zimmer J, Liao C, Tesfaye E, Hooshdaran N, Schofield JA, Bendor J, Fang D, Simon MD, Zamudio JR, Dimitrova N., Free PMC Article | 09/19/2020 |
| PVT1 exon 9 expression is important for prostate cancer initiation and progression, and holds promise as a therapeutic target in prostate cancer. | Long Noncoding RNA from PVT1 Exon 9 Is Overexpressed in Prostate Cancer and Induces Malignant Transformation and Castration Resistance in Prostate Epithelial Cells.
Pal G, Huaman J, Levine F, Orunmuyi A, Olapade-Olaopa EO, Onagoruwa OT, Ogunwobi OO., Free PMC Article | 05/16/2020 |
| Taken together, autophagy induction via the PVT1-miR-152-ATG14 signaling pathway contributes to activation of hepatic stellate cells under hypoxia condition. | Hypoxia induces the activation of hepatic stellate cells through the PVT1-miR-152-ATG14 signaling pathway.
Yu F, Dong B, Dong P, He Y, Zheng J, Xu P. | 03/21/2020 |
| We demonstrated that the lncRNA Pvt1, activated early during muscle atrophy, impacts mitochondrial respiration and morphology and affects mito/autophagy, apoptosis and myofiber size in vivo. | Single cell analysis reveals the involvement of the long non-coding RNA Pvt1 in the modulation of muscle atrophy and mitochondrial network.
Alessio E, Buson L, Chemello F, Peggion C, Grespi F, Martini P, Massimino ML, Pacchioni B, Millino C, Romualdi C, Bertoli A, Scorrano L, Lanfranchi G, Cagnin S., Free PMC Article | 08/24/2019 |
| lncRNA PVT1 promoted fibroblasts proliferation, collagen production, and mice atrial fibrosis via the miR-128-3p-Sp1-TGF-beta1-Smad axis. Our results indicate that PVT1 may serve as a novel therapeutic target for therapy for atrial fibrillation. | LncRNA PVT1 regulates atrial fibrosis via miR-128-3p-SP1-TGF-β1-Smad axis in atrial fibrillation.
Cao F, Li Z, Ding WM, Yan L, Zhao QY., Free PMC Article | 08/17/2019 |
| High PVT1 expression is associated with lung neoplasms. | Long noncoding RNA Pvt1 regulates the immunosuppression activity of granulocytic myeloid-derived suppressor cells in tumor-bearing mice.
Zheng Y, Tian X, Wang T, Xia X, Cao F, Tian J, Xu P, Ma J, Xu H, Wang S., Free PMC Article | 08/3/2019 |
| knockdown of long non-coding RNA PVT1 suppresses vascular smooth muscle cell apoptosis, extracellular matrix disruption, and serum pro-inflammatory cytokines in a murine Ang II-induced abdominal aortic aneurysm model. | Knockdown of lncRNA PVT1 Inhibits Vascular Smooth Muscle Cell Apoptosis and Extracellular Matrix Disruption in a Murine Abdominal Aortic Aneurysm Model.
Zhang Z, Zou G, Chen X, Lu W, Liu J, Zhai S, Qiao G., Free PMC Article | 05/18/2019 |
| Our results demonstrated that PVT1 was essential for the maintenance of cell size of cardiomyocytes and might play a role in the regulation of cardiac hypertrophy. | Cardiac hypertrophy is positively regulated by long non-coding RNA PVT1.
Yu YH, Hu ZY, Li MH, Li B, Wang ZM, Chen SL., Free PMC Article | 03/26/2016 |
| Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2. | Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2.
Wang F, Yuan JH, Wang SB, Yang F, Yuan SX, Ye C, Yang N, Zhou WP, Li WL, Li W, Sun SH. | 05/16/2015 |
| Gain of PVT1 long non-coding RNA expression was required for high MYC protein levels | PVT1 dependence in cancer with MYC copy-number increase.
Tseng YY, Moriarity BS, Gong W, Akiyama R, Tiwari A, Kawakami H, Ronning P, Reuland B, Guenther K, Beadnell TC, Essig J, Otto GM, O'Sullivan MG, Largaespada DA, Schwertfeger KL, Marahrens Y, Kawakami Y, Bagchi A., Free PMC Article | 10/4/2014 |
| Judging from the large number of integrations into the Pvt1 locus - more than in the nearby Myc locus - Pvt1 and the microRNAs encoded by it are as important as Myc in T lymphomagenesis, and, presumably, in T cell activation. | Pvt1-encoded microRNAs in oncogenesis.
Beck-Engeser GB, Lum AM, Huppi K, Caplen NJ, Wang BB, Wabl M., Free PMC Article | 01/21/2010 |