| A PrP EGFR signaling axis controls neural stem cell senescence through modulating cellular energy pathways. | A PrP EGFR signaling axis controls neural stem cell senescence through modulating cellular energy pathways.
Groveman BR, Schwarz B, Bohrnsen E, Foliaki ST, Carroll JA, Wood AR, Bosio CM, Haigh CL., Free PMC Article | 03/19/2024 |
| Mutations of evolutionarily conserved aromatic residues suggest that misfolding of the mouse prion protein may commence in multiple ways. | Mutations of evolutionarily conserved aromatic residues suggest that misfolding of the mouse prion protein may commence in multiple ways.
Pal S, Udgaonkar JB. | 12/16/2023 |
| Full-length prion protein incorporated into prion aggregates is a marker for prion strain-specific destabilization of aggregate structure following cellular uptake. | Full-length prion protein incorporated into prion aggregates is a marker for prion strain-specific destabilization of aggregate structure following cellular uptake.
Shoup D, Priola SA., Free PMC Article | 07/31/2023 |
| Cellular prion protein offers neuroprotection in astrocytes submitted to amyloid beta oligomer toxicity. | Cellular prion protein offers neuroprotection in astrocytes submitted to amyloid β oligomer toxicity.
Marques CMS, Gomes RN, Pedron T, Batista BL, Cerchiaro G. | 06/16/2023 |
| RAB7A GTPase Is Involved in Mitophagosome Formation and Autophagosome-Lysosome Fusion in N2a Cells Treated with the Prion Protein Fragment 106-126. | RAB7A GTPase Is Involved in Mitophagosome Formation and Autophagosome-Lysosome Fusion in N2a Cells Treated with the Prion Protein Fragment 106-126.
Li Z, Lai M, Li J, Yang D, Zhao M, Wang D, Sun Z, Wen P, Gou F, Dai Y, Ji Y, Zhao D, Qiao J, Yang L. | 02/14/2023 |
| Enhanced M-CSF/CSF1R Signaling Closely Associates with PrP(Sc) Accumulation in the Scrapie-Infected Cell Line and the Brains of Scrapie-Infected Experimental Rodents. | Enhanced M-CSF/CSF1R Signaling Closely Associates with PrP(Sc) Accumulation in the Scrapie-Infected Cell Line and the Brains of Scrapie-Infected Experimental Rodents.
Xia Y, Chen C, Chen J, Hu C, Yang W, Wang L, Liu L, Gao LP, Wu YZ, Chen DD, Shi Q, Chen ZB, Dong XP. | 09/24/2022 |
| The E3 Ubiquitin Ligase TRAF6 Interacts with the Cellular Prion Protein and Modulates Its Solubility and Recruitment to Cytoplasmic p62/SQSTM1-Positive Aggresome-Like Structures. | The E3 Ubiquitin Ligase TRAF6 Interacts with the Cellular Prion Protein and Modulates Its Solubility and Recruitment to Cytoplasmic p62/SQSTM1-Positive Aggresome-Like Structures.
Masperone L, Codrich M, Persichetti F, Gustincich S, Zucchelli S, Legname G. | 04/16/2022 |
| Dissociation of genotype-dependent cognitive and motor behavior in a strain of aging mice devoid of the prion protein. | Dissociation of genotype-dependent cognitive and motor behavior in a strain of aging mice devoid of the prion protein.
Janner DR, de Lima EV, da Silva RT, Clarke JR, Linden R. | 02/12/2022 |
| A Soluble PrP(C) Derivative and Membrane-Anchored PrP(C) in Extracellular Vesicles Attenuate Innate Immunity by Engaging the NMDA-R/LRP1 Receptor Complex. | A Soluble PrP(C) Derivative and Membrane-Anchored PrP(C) in Extracellular Vesicles Attenuate Innate Immunity by Engaging the NMDA-R/LRP1 Receptor Complex.
Mantuano E, Azmoon P, Banki MA, Sigurdson CJ, Campana WM, Gonias SL., Free PMC Article | 01/15/2022 |
| The Effects of Fibrinogen's Interactions with Its Neuronal Receptors, Intercellular Adhesion Molecule-1 and Cellular Prion Protein. | The Effects of Fibrinogen's Interactions with Its Neuronal Receptors, Intercellular Adhesion Molecule-1 and Cellular Prion Protein.
Sulimai N, Brown J, Lominadze D., Free PMC Article | 01/15/2022 |
| The cellular prion protein interacts with and promotes the activity of Na,K-ATPases. | The cellular prion protein interacts with and promotes the activity of Na,K-ATPases.
Williams D, Mehrabian M, Arshad H, Eid S, Sackmann C, Zhao W, Wang X, Ghodrati F, Verkuyl CE, Watts JC, Schmitt-Ulms G., Free PMC Article | 12/25/2021 |
| The protease-sensitive N-terminal polybasic region of prion protein modulates its conversion to the pathogenic prion conformer. | The protease-sensitive N-terminal polybasic region of prion protein modulates its conversion to the pathogenic prion conformer.
Zhang X, Pan YH, Chen Y, Pan C, Ma J, Yuan C, Yu G, Ma J., Free PMC Article | 12/18/2021 |
| Aggregation Condition-Structure Relationship of Mouse Prion Protein Fibrils. | Aggregation Condition-Structure Relationship of Mouse Prion Protein Fibrils.
Fridmanis J, Toleikis Z, Sneideris T, Ziaunys M, Bobrovs R, Smirnovas V, Jaudzems K., Free PMC Article | 10/30/2021 |
| Quaternary Structure Changes for PrP(Sc) Predate PrP(C) Downregulation and Neuronal Death During Progression of Experimental Scrapie Disease. | Quaternary Structure Changes for PrP(Sc) Predate PrP(C) Downregulation and Neuronal Death During Progression of Experimental Scrapie Disease.
Eskandari-Sedighi G, Cortez LM, Yang J, Daude N, Shmeit K, Sim V, Westaway D., Free PMC Article | 08/7/2021 |
| Cellular prion protein activates Caspase 3 for apoptotic defense mechanism in astrocytes. | Cellular prion protein activates Caspase 3 for apoptotic defense mechanism in astrocytes.
Marques CMS, Pedron T, Batista BL, Cerchiaro G. | 07/31/2021 |
| The prion protein is not required for peripheral nerve de- and remyelination after crush injury. | The prion protein is not required for peripheral nerve de- and remyelination after crush injury.
Henzi A, Aguzzi A., Free PMC Article | 06/26/2021 |
| Co-invalidation of Prnp and Sprn in FVB/N mice affects reproductive performances and highlight complex biological relationship between PrP and Shadoo. | Co-invalidation of Prnp and Sprn in FVB/N mice affects reproductive performances and highlight complex biological relationship between PrP and Shadoo.
Castille J, Passet B, Makhzami S, Vilotte M, Moazami-Goudarzi K, Truchet S, Daniel-Carlier N, Gaillard AL, Andréoletti O, Vaiman D, Beauvallet C, Vaiman A, Floriot S, Calvel P, Mouillet-Richard S, Duchesne A, Béringue V, Vilotte JL. | 06/12/2021 |
| Substrain-related dependence of Cu(I)-ATPase activity among prion protein-null mice. | Substrain-related dependence of Cu(I)-ATPase activity among prion protein-null mice.
Adão-Novaes J, Valverde RHF, Landemberger MC, Silveira MS, Simões-Pires EN, Lowe J, Linden R. | 04/13/2021 |
| Cellular prion protein dysfunction in a prototypical inherited metabolic myopathy. | Cellular prion protein dysfunction in a prototypical inherited metabolic myopathy.
Boufroura FZ, Tomkiewicz-Raulet C, Poindessous V, Castille J, Vilotte JL, Bastin J, Mouillet-Richard S, Djouadi F., Free PMC Article | 04/3/2021 |
| The uptake of tau amyloid fibrils is facilitated by the cellular prion protein and hampers prion propagation in cultured cells. | The uptake of tau amyloid fibrils is facilitated by the cellular prion protein and hampers prion propagation in cultured cells.
De Cecco E, Celauro L, Vanni S, Grandolfo M, Bistaffa E, Moda F, Aguzzi A, Legname G. | 03/6/2021 |
| Both N-Terminal and C-Terminal Histidine Residues of the Prion Protein Are Essential for Copper Coordination and Neuroprotective Self-Regulation. | Both N-Terminal and C-Terminal Histidine Residues of the Prion Protein Are Essential for Copper Coordination and Neuroprotective Self-Regulation.
Schilling KM, Tao L, Wu B, Kiblen JTM, Ubilla-Rodriguez NC, Pushie MJ, Britt RD, Roseman GP, Harris DA, Millhauser GL., Free PMC Article | 02/2/2021 |
| An astrocyte cell line that differentially propagates murine prions. | An astrocyte cell line that differentially propagates murine prions.
Tahir W, Abdulrahman B, Abdelaziz DH, Thapa S, Walia R, Schätzl HM., Free PMC Article | 01/23/2021 |
| The Prion-like protein Shadoo is involved in mouse embryonic and mammary development and differentiation. | The Prion-like protein Shadoo is involved in mouse embryonic and mammary development and differentiation.
Passet B, Castille J, Makhzami S, Truchet S, Vaiman A, Floriot S, Moazami-Goudarzi K, Vilotte M, Gaillard AL, Helary L, Bertaud M, Andréoletti O, Vaiman D, Calvel P, Daniel-Carlier N, Moudjou M, Beauvallet C, Benharouga M, Laloé D, Mouillet-Richard S, Duchesne A, Béringue V, Vilotte JL., Free PMC Article | 12/12/2020 |
| Formation of distinct prion protein amyloid fibrils under identical experimental conditions. | Formation of distinct prion protein amyloid fibrils under identical experimental conditions.
Ziaunys M, Sneideris T, Smirnovas V., Free PMC Article | 12/5/2020 |
| Conformation-dependent membrane permeabilization by neurotoxic PrP oligomers: The role of the H2H3 oligomerization domain. | Conformation-dependent membrane permeabilization by neurotoxic PrP oligomers: The role of the H2H3 oligomerization domain.
Huin C, Cronier S, Guégan P, Béringue V, Rezaei H, Noinville S. | 11/21/2020 |