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    EDNRB endothelin receptor type B [ Homo sapiens (human) ]

    Gene ID: 1910, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Structure of endothelin ETB receptor-Gi complex in a conformation stabilized by unique NPxxL motif.

    Structure of endothelin ET(B) receptor-G(i) complex in a conformation stabilized by unique NPxxL motif.
    Tani K, Maki-Yonekura S, Kanno R, Negami T, Hamaguchi T, Hall M, Mizoguchi A, Humbel BM, Terada T, Yonekura K, Doi T., Free PMC Article

    10/25/2024
    Molecular mechanism of the endothelin receptor type B interactions with Gs, Gi, and Gq.

    Molecular mechanism of the endothelin receptor type B interactions with Gs, Gi, and Gq.
    Ham D, Shihoya W, Nureki O, Inoue A, Chung KY.

    10/10/2024
    Endothelin 3/EDNRB signaling induces thermogenic differentiation of white adipose tissue.

    Endothelin 3/EDNRB signaling induces thermogenic differentiation of white adipose tissue.
    Wang CH, Tsuji T, Wu LH, Yang CY, Huang TL, Sato M, Shamsi F, Tseng YH., Free PMC Article

    10/3/2024
    Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ETA and ETB receptors in human cardiorenal tissue.

    Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ETA and ETB receptors in human cardiorenal tissue.
    Williams TL, Kuc RE, Paterson AL, Abraham GR, Pullinger AL, Maguire JJ, Sinha S, Greasley PJ, Ambery P, Davenport AP., Free PMC Article

    06/13/2024
    High incidence of EDNRB gene mutation in seven southern Chinese familial cases with Hirschsprung's disease.

    High incidence of EDNRB gene mutation in seven southern Chinese familial cases with Hirschsprung's disease.
    Ding HY, Lei W, Xiao SJ, Deng H, Yuan LK, Xu L, Zhou JL, Huang R, Fang YL, Wang QY, Zhang Y, Zhang L, Zhu XC.

    02/1/2024
    Women Have Greater Endothelin-B Receptor Function and Lower Mitochondrial Capacity Compared to Men With Type 1 Diabetes.

    Women Have Greater Endothelin-B Receptor Function and Lower Mitochondrial Capacity Compared to Men With Type 1 Diabetes.
    Derella CC, Thomas J, Harris RA., Free PMC Article

    09/20/2023
    MiRNA-19b-3p downregulates the endothelin B receptor in gastric cancer cells to prevent angiogenesis and proliferation.

    MiRNA-19b-3p downregulates the endothelin B receptor in gastric cancer cells to prevent angiogenesis and proliferation.
    Hu X, Liu H, Li C.

    06/23/2023
    Roles of Astrocytic Endothelin ETB Receptor in Traumatic Brain Injury.

    Roles of Astrocytic Endothelin ET(B) Receptor in Traumatic Brain Injury.
    Michinaga S, Hishinuma S, Koyama Y., Free PMC Article

    03/14/2023
    Identification of nine novel variants across PAX3, SOX10, EDNRB, and MITF genes in Waardenburg syndrome with next-generation sequencing.

    Identification of nine novel variants across PAX3, SOX10, EDNRB, and MITF genes in Waardenburg syndrome with next-generation sequencing.
    Lee CY, Lo MY, Chen YM, Lin PH, Hsu CJ, Chen PL, Wu CC, Hsu JS., Free PMC Article

    12/24/2022
    High Glucose-Induced Cardiomyocyte Damage Involves Interplay between Endothelin ET-1/ETA/ETB Receptor and mTOR Pathway.

    High Glucose-Induced Cardiomyocyte Damage Involves Interplay between Endothelin ET-1/ET(A)/ET(B) Receptor and mTOR Pathway.
    Pandey S, Madreiter-Sokolowski CT, Mangmool S, Parichatikanond W., Free PMC Article

    12/10/2022
    Endothelin B Receptor Immunodynamics in Pulmonary Arterial Hypertension.

    Endothelin B Receptor Immunodynamics in Pulmonary Arterial Hypertension.
    Tabeling C, González Calera CR, Lienau J, Höppner J, Tschernig T, Kershaw O, Gutbier B, Naujoks J, Herbert J, Opitz B, Gruber AD, Hocher B, Suttorp N, Heidecke H, Burmester GR, Riemekasten G, Siegert E, Kuebler WM, Witzenrath M., Free PMC Article

    07/2/2022
    Genetic heterogeneity in GJB2, COL4A3, ATP6V1B1 and EDNRB variants detected among hearing impaired families in Morocco.

    Genetic heterogeneity in GJB2, COL4A3, ATP6V1B1 and EDNRB variants detected among hearing impaired families in Morocco.
    AitRaise I, Amalou G, Bousfiha A, Charoute H, Rouba H, Abdelghaffar H, Bonnet C, Petit C, Barakat A.

    06/18/2022
    A large Canadian cohort provides insights into the genetic architecture of human hair colour.

    A large Canadian cohort provides insights into the genetic architecture of human hair colour.
    Lona-Durazo F, Mendes M, Thakur R, Funderburk K, Zhang T, Kovacs MA, Choi J, Brown KM, Parra EJ., Free PMC Article

    12/25/2021
    Novel variants in EDNRB gene in Waardenburg syndrome type II and SOX10 gene in PCWH syndrome.

    Novel variants in EDNRB gene in Waardenburg syndrome type II and SOX10 gene in PCWH syndrome.
    Varga L, Danis D, Drsata J, Masindova I, Skopkova M, Slobodova Z, Chrobok V, Profant M, Gasperikova D.

    08/7/2021
    Inhibition of endothelin-B receptor signaling synergizes with MAPK pathway inhibitors in BRAF mutated melanoma.

    Inhibition of endothelin-B receptor signaling synergizes with MAPK pathway inhibitors in BRAF mutated melanoma.
    Schäfer A, Haenig B, Erupathil J, Strickner P, Sabato D, Welford RWD, Klaeylé L, Simon E, Krepler C, Brafford P, Xiao M, Herlyn M, Gstaiger M, Lehembre F, Renz I.

    07/31/2021
    Endothelin receptor heteromerization inhibits beta-arrestin function in HEK293 cells.

    Endothelin receptor heteromerization inhibits β-arrestin function in HEK293 cells.
    Zrein A, Bagher AM, Young AP, Denovan-Wright EM, Kelly MEM.

    06/5/2021
    Endothelin ETB Receptor-Mediated Astrocytic Activation: Pathological Roles in Brain Disorders.

    Endothelin ET(B) Receptor-Mediated Astrocytic Activation: Pathological Roles in Brain Disorders.
    Koyama Y., Free PMC Article

    05/22/2021
    Significant Association of rs2147555 Genetic Polymorphism in the EDNRB Gene with Hirschsprung Disease in Southern Chinese Children.

    Significant Association of rs2147555 Genetic Polymorphism in the EDNRB Gene with Hirschsprung Disease in Southern Chinese Children.
    Zheng Y, Lan C, Wang N, Xu X, Hu T, Wu Q, Xie X, Wang Z, Zhang Y, Li C., Free PMC Article

    05/8/2021
    Prediction of prognostic signatures in triple-negative breast cancer based on the differential expression analysis via NanoString nCounter immune panel.

    Prediction of prognostic signatures in triple-negative breast cancer based on the differential expression analysis via NanoString nCounter immune panel.
    Lim GB, Kim YA, Seo JH, Lee HJ, Gong G, Park SH., Free PMC Article

    04/24/2021
    Role of endothelin receptor type B (EDNRB) in lung adenocarcinoma.

    Role of endothelin receptor type B (EDNRB) in lung adenocarcinoma.
    Wei F, Ge Y, Li W, Wang X, Chen B., Free PMC Article

    03/13/2021
    Growth factor and receptor malfunctions associated with human genetic deafness.

    Growth factor and receptor malfunctions associated with human genetic deafness.
    Naz S, Friedman TB., Free PMC Article

    02/6/2021
    Characterization of Critical Residues in the Extracellular and Transmembrane Domains of the Endothelin Type B Receptor for Propagation of the Endothelin-1 Signal.

    Characterization of Critical Residues in the Extracellular and Transmembrane Domains of the Endothelin Type B Receptor for Propagation of the Endothelin-1 Signal.
    Doi T, Kikuta K, Tani K.

    01/23/2021
    Crystal structure of human endothelin ETB receptor in complex with sarafotoxin S6b.

    Crystal structure of human endothelin ET(B) receptor in complex with sarafotoxin S6b.
    Izume T, Miyauchi H, Shihoya W, Nureki O.

    01/16/2021
    The value of endothelin receptor type B promoter methylation as a biomarker for the risk assessment and diagnosis of prostate cancer: A meta-analysis.

    The value of endothelin receptor type B promoter methylation as a biomarker for the risk assessment and diagnosis of prostate cancer: A meta-analysis.
    Yuan Y, Du Y, Wang L, Liu X.

    12/19/2020
    Altered endothelial ETB receptor expression in postmenopausal women.

    Altered endothelial ET(B) receptor expression in postmenopausal women.
    Kuczmarski AV, Shoemaker LN, Hobson JC, Edwards DG, Wenner MM., Free PMC Article

    10/10/2020
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