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    ABCA1 ATP binding cassette subfamily A member 1 [ Homo sapiens (human) ]

    Gene ID: 19, updated on 5-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    ABCA1 variant rs9282541 is associated with metabolic syndrome in Maya children.

    ABCA1 variant rs9282541 is associated with metabolic syndrome in Maya children.
    Peña-Espinoza BI, Torre-Horta E, Ortiz-López MG, Menjivar M.

    11/5/2024
    The ATPase activity of ABCA1 is increased by cholesterol in the presence of anionic lipids.

    The ATPase activity of ABCA1 is increased by cholesterol in the presence of anionic lipids.
    Sakata K, Kioka N, Ueda K, Kimura Y.

    10/23/2024
    Involvement of Expression of miR33-5p and ABCA1 in Human Peripheral Blood Mononuclear Cells in Coronary Artery Disease.

    Involvement of Expression of miR33-5p and ABCA1 in Human Peripheral Blood Mononuclear Cells in Coronary Artery Disease.
    Torres-Paz YE, Gamboa R, Fuentevilla-Álvarez G, Cardoso-Saldaña G, Martínez-Alvarado R, Soto ME, Huesca-Gómez C., Free PMC Article

    10/7/2024
    The ABCA1 gene polymorphisms rs1800977 and rs2230806 are differentially associated with the risk for myocardial infarction in Slovenian subjects with type 2 diabetes mellitus.

    The ABCA1 gene polymorphisms rs1800977 and rs2230806 are differentially associated with the risk for myocardial infarction in Slovenian subjects with type 2 diabetes mellitus.
    Boh J, Šuligoj E, Mankoč Ramuš S, Petrovič D.

    07/29/2024
    Identification and Molecular Simulation of Genetic Variants in ABCA1 Gene Associated with Susceptibility to Dyslipidemia in Type 2 Diabetes.

    Identification and Molecular Simulation of Genetic Variants in ABCA1 Gene Associated with Susceptibility to Dyslipidemia in Type 2 Diabetes.
    Majeed A, Baig ZA, Rashid A., Free PMC Article

    07/17/2024
    Decreased mRNA expression of NR1H3 and ABCA1 in pulmonary tuberculosis patients from population of Punjab, India.

    Decreased mRNA expression of NR1H3 and ABCA1 in pulmonary tuberculosis patients from population of Punjab, India.
    Kumari A, Saini V, Kumar V.

    07/10/2024
    Inflammatory corpuscle AIM2 facilitates macrophage foam cell formation by inhibiting cholesterol efflux protein ABCA1.

    Inflammatory corpuscle AIM2 facilitates macrophage foam cell formation by inhibiting cholesterol efflux protein ABCA1.
    Zhuo S, Song S, Wang C, Wang Z, Zhang M, Lin D, Chen K., Free PMC Article

    07/3/2024
    ALKBH5 facilitates the progression of skin cutaneous melanoma via mediating ABCA1 demethylation and modulating autophagy in an m[6]A-dependent manner.

    ALKBH5 facilitates the progression of skin cutaneous melanoma via mediating ABCA1 demethylation and modulating autophagy in an m(6)A-dependent manner.
    Wang H, Zhao S, Liu H, Liu Y, Zhang Z, Zhou Z, Wang P, Qi S, Xie J., Free PMC Article

    03/15/2024
    Trimethylamine N-oxide promotes oxidative stress and lipid accumulation in macrophage foam cells via the Nrf2/ABCA1 pathway.

    Trimethylamine N-oxide promotes oxidative stress and lipid accumulation in macrophage foam cells via the Nrf2/ABCA1 pathway.
    Luo Z, Yu X, Wang C, Zhao H, Wang X, Guan X.

    02/14/2024
    Functional characterization of missense variants affecting the extracellular domains of ABCA1 using a fluorescence-based assay.

    Functional characterization of missense variants affecting the extracellular domains of ABCA1 using a fluorescence-based assay.
    Teigen M, Ølnes ÅS, Bjune K, Leren TP, Bogsrud MP, Strøm TB., Free PMC Article

    01/30/2024
    Lipid reprogramming induced by the NNMT-ABCA1 axis enhanced membrane fluidity to promote endometrial cancer progression.

    Lipid reprogramming induced by the NNMT-ABCA1 axis enhanced membrane fluidity to promote endometrial cancer progression.
    Wen Q, Xie X, Chen C, Wen B, Liu Y, Zhou J, Lin X, Jin H, Shi K., Free PMC Article

    11/30/2023
    Increased Expression of the ABCA1 and ABCA3 Transporter Genes is Associated with Cisplatin Resistance in Breast Cancer Cells.

    Increased Expression of the ABCA1 and ABCA3 Transporter Genes is Associated with Cisplatin Resistance in Breast Cancer Cells.
    Al-Shumary DS, Al-Shammari AM, Rasheed MN., Free PMC Article

    11/30/2023
    Primary open-angle glaucoma risk prediction with ABCA1 and LOC102723944 variants and their genotype-phenotype correlations in southern Chinese population.

    Primary open-angle glaucoma risk prediction with ABCA1 and LOC102723944 variants and their genotype-phenotype correlations in southern Chinese population.
    Wu Z, Huang C, Zheng Y, Yuan XL, Chen S, Xu Y, Chen LJ, Pang CP, Zhang M, Ng TK.

    11/20/2023
    Integration of methylation quantitative trait loci (mQTL) on dietary intake on DNA methylation levels: an example of n-3 PUFA and ABCA1 gene.

    Integration of methylation quantitative trait loci (mQTL) on dietary intake on DNA methylation levels: an example of n-3 PUFA and ABCA1 gene.
    Fujii R, Ando Y, Yamada H, Tsuboi Y, Munetsuna E, Yamazaki M, Mizuno G, Maeda K, Ohashi K, Ishikawa H, Watanabe M, Imaeda N, Goto C, Wakai K, Hashimoto S, Suzuki K.

    11/15/2023
    The role of the ATP-Binding Cassette A1 (ABCA1) in neurological disorders: a mechanistic review.

    The role of the ATP-Binding Cassette A1 (ABCA1) in neurological disorders: a mechanistic review.
    Paseban T, Alavi MS, Etemad L, Roohbakhsh A.

    11/3/2023
    Expression analysis of ABCA1 in type 2 diabetic Pakistani patients with and without dyslipidemia and correlation with glycemic index and lipid profile.

    Expression analysis of ABCA1 in type 2 diabetic Pakistani patients with and without dyslipidemia and correlation with glycemic index and lipid profile.
    Zaidi A, Rashid A, Majeed A, Naeem A, Akram W, Baig ZA., Free PMC Article

    11/2/2023
    Genetic variants in the adenosine triphosphate-binding cassette transporter A1 and risk of age-related macular degeneration.

    Genetic variants in the adenosine triphosphate-binding cassette transporter A1 and risk of age-related macular degeneration.
    Nordestgaard LT, Christoffersen M, Afzal S, Nordestgaard BG, Tybjærg-Hansen A, Frikke-Schmidt R., Free PMC Article

    11/1/2023
    Drug metabolism-related gene ABCA1 augments temozolomide chemoresistance and immune infiltration abundance of M2 macrophages in glioma.

    Drug metabolism-related gene ABCA1 augments temozolomide chemoresistance and immune infiltration abundance of M2 macrophages in glioma.
    Yan Y, Liu Y, Liang Q, Xu Z., Free PMC Article

    09/29/2023
    Phospholipid transport by ABCA1: the extracellular translocase or alternating access model?

    Phospholipid transport by ABCA1: the extracellular translocase or alternating access model?
    Segrest JP, Davidson WS, Heinecke JW., Free PMC Article

    09/12/2023
    ABCA1 transporter promotes the motility of human melanoma cells by modulating their plasma membrane organization.

    ABCA1 transporter promotes the motility of human melanoma cells by modulating their plasma membrane organization.
    Wu A, Mazurkiewicz E, Donizy P, Kotowski K, Pieniazek M, Mazur AJ, Czogalla A, Trombik T., Free PMC Article

    06/22/2023
    The roles of ATP-binding cassette transporter A1 and its substrate cholesterol in head and neck cancers.

    The roles of ATP-binding cassette transporter A1 and its substrate cholesterol in head and neck cancers.
    Sanli F, Karatas OF.

    06/19/2023
    Association of ABCA1 R219K polymorphism and telomere length in a Chinese rural population: possible linking to systemic inflammation.

    Association of ABCA1 R219K polymorphism and telomere length in a Chinese rural population: possible linking to systemic inflammation.
    Liao S, Zhou Q, Zhang Y.

    05/22/2023
    APOC3 and ABCA1 variants in unusual combined hypolipidaemia showing premature peripheral vascular disease.

    APOC3 and ABCA1 variants in unusual combined hypolipidaemia showing premature peripheral vascular disease.
    Pos Z, Khedr M, Radvanszky J, Penesova A, Hekel R, Szemes T, Ranganath LR, Zatkova A.

    04/14/2023
    Lack of Association of Polymorphism Located Upstream of ABCA1 (rs2472493), in FNDC3B (rs7636836), and Near ANKRD55-MAP3K1 Genes (rs61275591) in Primary Open-Angle Glaucoma Patients of Saudi Origin.

    Lack of Association of Polymorphism Located Upstream of ABCA1 (rs2472493), in FNDC3B (rs7636836), and Near ANKRD55-MAP3K1 Genes (rs61275591) in Primary Open-Angle Glaucoma Patients of Saudi Origin.
    Kondkar AA, Sultan T, Azad TA, Osman EA, Almobarak FA, Lobo GP, Al-Obeidan SA., Free PMC Article

    03/30/2023
    Insulin Downregulates the Expression of ATP-binding Cassette Transporter A-I in Human Hepatoma Cell Line HepG2 in a FOXO1 and LXR Dependent Manner.

    Insulin Downregulates the Expression of ATP-binding Cassette Transporter A-I in Human Hepatoma Cell Line HepG2 in a FOXO1 and LXR Dependent Manner.
    Shavva VS, Babina AV, Nekrasova EV, Lisunov AV, Dizhe EB, Oleinikova GN, Orlov SV.

    02/23/2023
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