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    Pax6 paired box 6 [ Mus musculus (house mouse) ]

    Gene ID: 18508, updated on 5-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Effects of miR-204-5p modulation on PAX6 regulation and corneal inflammation.

    Effects of miR-204-5p modulation on PAX6 regulation and corneal inflammation.
    Abbasi M, Amini M, Moustardas P, Gutsmiedl Q, Javidjam D, Suiwal S, Seitz B, Fries FN, Dashti A, Rautavaara Y, Stachon T, Szentmáry N, Lagali N., Free PMC Article

    11/5/2024
    IGF2BP2 Maintains Retinal Pigment Epithelium Homeostasis by Stabilizing PAX6 and OTX2.

    IGF2BP2 Maintains Retinal Pigment Epithelium Homeostasis by Stabilizing PAX6 and OTX2.
    Wu S, Li F, Mo K, Huang H, Yu Y, Huang Y, Liu J, Li M, Tan J, Lin Z, Han Z, Wang L, Ouyang H., Free PMC Article

    07/11/2024
    Pax6 isoforms shape eye development: Insights from developmental stages and organoid models.

    Pax6 isoforms shape eye development: Insights from developmental stages and organoid models.
    Hung SS, Tsai PS, Po CW, Hou PS.

    06/18/2024
    A positive feedback inhibition of isocitrate dehydrogenase 3beta on paired-box gene 6 promotes Alzheimer-like pathology.

    A positive feedback inhibition of isocitrate dehydrogenase 3β on paired-box gene 6 promotes Alzheimer-like pathology.
    Wang X, Liu Q, Yu HT, Xie JZ, Zhao JN, Fang ZT, Qu M, Zhang Y, Yang Y, Wang JZ., Free PMC Article

    05/29/2024
    Characterization of neural damage and neuroinflammation in Pax6 small-eye mice.

    Characterization of neural damage and neuroinflammation in Pax6 small-eye mice.
    Cole JD, McDaniel JA, Nilak J, Ban A, Rodriguez C, Hameed Z, Grannonico M, Netland PA, Yang H, Provencio I, Liu X.,

    01/8/2024
    Pax6 affects Ras-Raf-ERK1/2 in mouse aging brain.

    Pax6 affects Ras-Raf-ERK1/2 in mouse aging brain.
    Srivastava K, Mishra R.

    11/1/2023
    Long noncoding RNA MALAT1 inhibition attenuates sepsis-induced acute lung injury through modulating the miR-129-5p/PAX6/ZEB2 axis.

    Long noncoding RNA MALAT1 inhibition attenuates sepsis-induced acute lung injury through modulating the miR-129-5p/PAX6/ZEB2 axis.
    Li Y, Xiao W, Lin X.

    03/7/2023
    Pregnenolone enhances the proliferation of mouse neural stem cells and promotes oligodendrogenesis, together with Sox10, and neurogenesis, along with Notch1 and Pax6.

    Pregnenolone enhances the proliferation of mouse neural stem cells and promotes oligodendrogenesis, together with Sox10, and neurogenesis, along with Notch1 and Pax6.
    Negintaji K, Ghanbari A, Frozanfar M, Jafarinia M, Zibara K.

    03/2/2023
    Co-expression and Interaction of Pax6 with Genes and Proteins of Immunological Surveillance in the Brain of Mice.

    Co-expression and Interaction of Pax6 with Genes and Proteins of Immunological Surveillance in the Brain of Mice.
    Maurya SK, Mishra R.

    01/11/2023
    Pax6 mutant cerebral organoids partially recapitulate phenotypes of Pax6 mutant mouse strains.

    Pax6 mutant cerebral organoids partially recapitulate phenotypes of Pax6 mutant mouse strains.
    Ferdaos N, Lowell S, Mason JO., Free PMC Article

    12/10/2022
    Identification of PAX6 and NFAT4 as the Transcriptional Regulators of the Long Noncoding RNA Mrhl in Neuronal Progenitors.

    Identification of PAX6 and NFAT4 as the Transcriptional Regulators of the Long Noncoding RNA Mrhl in Neuronal Progenitors.
    Pal D, Dutta S, Iyer DP, Shriram D, Bhaduri U, Rao MRS., Free PMC Article

    11/26/2022
    Paired Box Gene 6 Regulates Heme Oxygenase-1 Expression and Mitigates Hydrogen Peroxide-Induced Oxidative Stress in Lens Epithelial Cells.

    Paired Box Gene 6 Regulates Heme Oxygenase-1 Expression and Mitigates Hydrogen Peroxide-Induced Oxidative Stress in Lens Epithelial Cells.
    Zheng Y, Yang X, Wu S, Yi G, Huang X, Feng Z, Qu L, Liu L, Li Q, Xia Z.

    10/22/2022
    Autoregulation of Pax6 in neuronal cells is mediated by Pax6(5a), Pax6(DeltaPD), SPARC, and p53.

    Autoregulation of Pax6 in neuronal cells is mediated by Pax6(5a), Pax6(ΔPD), SPARC, and p53.
    Shukla S, Mishra R.

    04/2/2022
    RYBP regulates Pax6 during in vitro neural differentiation of mouse embryonic stem cells.

    RYBP regulates Pax6 during in vitro neural differentiation of mouse embryonic stem cells.
    Sutus E, Henry S, Adorján L, Kovács G, Pirity MK., Free PMC Article

    03/19/2022
    Transcriptional cooperation of PBX1 and PAX6 in adult neural progenitor cells.

    Transcriptional cooperation of PBX1 and PAX6 in adult neural progenitor cells.
    Hau AC, Mommaerts E, Laub V, Müller T, Dittmar G, Schulte D., Free PMC Article

    01/29/2022
    PAX6 missense variants in two families with isolated foveal hypoplasia and nystagmus: evidence of paternal postzygotic mosaicism.

    PAX6 missense variants in two families with isolated foveal hypoplasia and nystagmus: evidence of paternal postzygotic mosaicism.
    Lima Cunha D, Owen N, Tailor V, Corton M, Theodorou M, Moosajee M., Free PMC Article

    01/22/2022
    Insm1, Neurod1, and Pax6 promote murine pancreatic endocrine cell development through overlapping yet distinct RNA transcription and splicing programs.

    Insm1, Neurod1, and Pax6 promote murine pancreatic endocrine cell development through overlapping yet distinct RNA transcription and splicing programs.
    Dudek KD, Osipovich AB, Cartailler JP, Gu G, Magnuson MA., Free PMC Article

    01/15/2022
    Kappa opioid receptor controls neural stem cell differentiation via a miR-7a/Pax6 dependent pathway.

    Kappa opioid receptor controls neural stem cell differentiation via a miR-7a/Pax6 dependent pathway.
    Xu C, Fan W, Zhang Y, Loh HH, Law PY.

    12/11/2021
    Long noncoding RNA PM maintains cerebellar synaptic integrity and Cbln1 activation via Pax6/Mll1-mediated H3K4me3.

    Long noncoding RNA PM maintains cerebellar synaptic integrity and Cbln1 activation via Pax6/Mll1-mediated H3K4me3.
    Jin Y, Zhang B, Lu J, Song Y, Wang W, Zhang W, Shao F, Gong M, Wang M, Liang X, Li S, Zhang Z, Shan G, Wang X., Free PMC Article

    10/2/2021
    Smad3 deficiency promotes beta cell proliferation and function in db/db mice via restoring Pax6 expression.

    Smad3 deficiency promotes beta cell proliferation and function in db/db mice via restoring Pax6 expression.
    Sheng J, Wang L, Tang PM, Wang HL, Li JC, Xu BH, Xue VW, Tan RZ, Jin N, Chan TF, Huang XR, Ma RC, Lan HY., Free PMC Article

    07/31/2021
    Global and age-related neuroanatomical abnormalities in a Pax6-deficient mouse model of aniridia suggests a role for Pax6 in adult structural neuroplasticity.

    Global and age-related neuroanatomical abnormalities in a Pax6-deficient mouse model of aniridia suggests a role for Pax6 in adult structural neuroplasticity.
    Grant MK, Bobilev AM, Rasys AM, Branson Byers J, Schriever HC, Hekmatyar K, Lauderdale JD., Free PMC Article

    07/31/2021
    PAX6 mutation alters circadian rhythm and beta cell function in mice without affecting glucose tolerance.

    PAX6 mutation alters circadian rhythm and β cell function in mice without affecting glucose tolerance.
    Chhabra NF, Amarie OV, Wu M, Amend AL, Rubey M, Gradinger D, Irmler M, Beckers J, Rathkolb B, Wolf E, Feuchtinger A, Huypens P, Teperino R, Rozman J, Przemeck GKH, Hrabě de Angelis M., Free PMC Article

    07/3/2021
    Extracellular Pax6 Regulates Tangential Cajal-Retzius Cell Migration in the Developing Mouse Neocortex.

    Extracellular Pax6 Regulates Tangential Cajal-Retzius Cell Migration in the Developing Mouse Neocortex.
    Kaddour H, Coppola E, Di Nardo AA, Le Poupon C, Mailly P, Wizenmann A, Volovitch M, Prochiantz A, Pierani A.

    06/19/2021
    Stem cell regionalization during olfactory bulb neurogenesis depends on regulatory interactions between Vax1 and Pax6.

    Stem cell regionalization during olfactory bulb neurogenesis depends on regulatory interactions between Vax1 and Pax6.
    Coré N, Erni A, Hoffmann HM, Mellon PL, Saurin AJ, Beclin C, Cremer H., Free PMC Article

    02/27/2021
    Paired box 6 inhibits cardiac fibroblast differentiation.

    Paired box 6 inhibits cardiac fibroblast differentiation.
    Feng Y, Li M, Wang S, Cong W, Hu G, Song Y, Xiao H, Dong E, Zhang Y.

    02/13/2021
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