| Inflammatory response and parasite regulation in acute toxoplasmosis: the role of P2X7 receptor in controlling virulent atypical genotype strain of Toxoplasma gondii. | Inflammatory response and parasite regulation in acute toxoplasmosis: the role of P2X7 receptor in controlling virulent atypical genotype strain of Toxoplasma gondii.
Prado-Rangel T, Moreira-Souza ACA, da Silva SRB, Barboza-Araujo T, Castro-Junior AB, Ramos IPR, Takiya CM, Vommaro RC, Coutinho-Silva R., Free PMC Article | 11/5/2024 |
| P2X7 expression patterns in the developing Fmr1-knockout mouse hippocampus. | P2X7 expression patterns in the developing Fmr1-knockout mouse hippocampus.
Napier M, Kumar A, Szulist N, Martin D, Scott AL. | 10/29/2024 |
| P2X7 receptors modulate acquisition of cue fear extinction and contextual background memory generalization in male mice. | P2X7 receptors modulate acquisition of cue fear extinction and contextual background memory generalization in male mice.
Domingos LB, Silva Júnior AFD, Diniz CRAF, Rosa J, Terzian ALB, Resstel LBM. | 10/25/2024 |
| Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice. | Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice.
Alves M, Gil B, Villegas-Salmerón J, Salari V, Martins-Ferreira R, Arribas Blázquez M, Menéndez Méndez A, Da Rosa Gerbatin R, Smith J, de Diego-Garcia L, Conte G, Sierra-Marquez J, Merino Serrais P, Mitra M, Fernandez Martin A, Wang Y, Kesavan J, Melia C, Parras A, Beamer E, Zimmer B, Heiland M, Cavanagh B, Parcianello Cipolat R, Morgan J, Teng X, Prehn JHM, Fabene PF, Bertini G, Artalejo AR, Ballestar E, Nicke A, Olivos-Oré LA, Connolly NMC, Henshall DC, Engel T. | 08/28/2024 |
| New mechanistic understanding of osteoclast differentiation and bone resorption mediated by P2X7 receptors and PI3K-Akt-GSK3beta signaling. | New mechanistic understanding of osteoclast differentiation and bone resorption mediated by P2X7 receptors and PI3K-Akt-GSK3β signaling.
Lu J, Shi X, Fu Q, Han Y, Zhu L, Zhou Z, Li Y, Lu N., Free PMC Article | 08/2/2024 |
| P2X7R and P2X4R expression of mice submandibular gland in high-fat diet/streptozotocin-induced type 2 diabetes. | P2X7R and P2X4R expression of mice submandibular gland in high-fat diet/streptozotocin-induced type 2 diabetes.
Srisutha J, Watari I, Akakura M, Watanabe M, Changsiripun C, Ono T., Free PMC Article | 07/11/2024 |
| P2X7-Mediated Antigen-Independent Activation of CD8[+] T Cells Promotes Salt-Sensitive Hypertension. | P2X7-Mediated Antigen-Independent Activation of CD8(+) T Cells Promotes Salt-Sensitive Hypertension.
Benson LN, Deck KS, Mora CJ, Guo Y, Rafferty TM, Li LX, Huang L, Andrews JT, Qin Z, Trott DW, Hoover RS, Liu Y, Mu S., | 06/27/2024 |
| Angiotension II directly bind P2X7 receptor to induce myocardial ferroptosis and remodeling by activating human antigen R. | Angiotension II directly bind P2X7 receptor to induce myocardial ferroptosis and remodeling by activating human antigen R.
Zhong X, Wang K, Wang Y, Wang L, Wang S, Huang W, Jia Z, Dai SS, Huang Z., Free PMC Article | 05/29/2024 |
| The purinergic receptor P2X7 as a modulator of viral vector-mediated antigen cross-presentation. | The purinergic receptor P2X7 as a modulator of viral vector-mediated antigen cross-presentation.
Longo Y, Mascaraque SM, Andreacchio G, Werner J, Katahira I, De Marchi E, Pegoraro A, Lebbink RJ, Köhrer K, Petzsch P, Tao R, Di Virgilio F, Adinolfi E, Drexler I., Free PMC Article | 05/29/2024 |
| Upregulation of P2X7 Exacerbates Myocardial Ischemia-Reperfusion Injury through Enhancing Inflammation and Apoptosis in Diabetic Mice. | Upregulation of P2X7 Exacerbates Myocardial Ischemia-Reperfusion Injury through Enhancing Inflammation and Apoptosis in Diabetic Mice.
Wu F, Wei H, Hu Y, Gao J, Xu S., Free PMC Article | 03/22/2024 |
| Disruption of the Na[+]/K[+]-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety. | Disruption of the Na(+)/K(+)-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety.
Huang S, Dong W, Lin X, Xu K, Li K, Xiong S, Wang Z, Nie X, Bian JS. | 03/21/2024 |
| P2X7 receptor of olfactory bulb microglia plays a pathogenic role in stress-related depression in mice with allergic rhinitis. | P2X7 receptor of olfactory bulb microglia plays a pathogenic role in stress-related depression in mice with allergic rhinitis.
Mou Y, Sun C, Wei S, Song X, Wang H, Wang Y, Ren C, Song X. | 03/1/2024 |
| P2Y2-P2X7 receptors cross-talk in primed mesenteric endothelial cells upregulates NF-kappaB signaling favoring mononuclear cell adhesion in schistosomiasis. | P2Y(2)-P2X7 receptors cross-talk in primed mesenteric endothelial cells upregulates NF-κB signaling favoring mononuclear cell adhesion in schistosomiasis.
Oliveira NF, Monteiro MMLV, Mainieri NS, Tamura AS, Pereira LM, Crepaldi LD, Coutinho-Silva R, Savio LEB, Silva CLM., Free PMC Article | 01/31/2024 |
| Caveolin-1 forms a complex with P2X7 receptor and tunes P2X7-mediated ATP signaling in mouse bone marrow-derived macrophages. | Caveolin-1 forms a complex with P2X7 receptor and tunes P2X7-mediated ATP signaling in mouse bone marrow-derived macrophages.
Sawai Y, Suzuki Y, Asagiri M, Hida S, Kondo R, Zamponi GW, Giles WR, Imaizumi Y, Yamamura H. | 01/9/2024 |
| T cell-specific P2RX7 favors lung parenchymal CD4[+] T cell accumulation in response to severe lung infections. | T cell-specific P2RX7 favors lung parenchymal CD4(+) T cell accumulation in response to severe lung infections.
Santiago-Carvalho I, Almeida-Santos G, Macedo BG, Barbosa-Bomfim CC, Almeida FM, Pinheiro Cione MV, Vardam-Kaur T, Masuda M, Van Dijk S, Melo BM, Silva do Nascimento R, da Conceição Souza R, Peixoto-Rangel AL, Coutinho-Silva R, Hirata MH, Alves-Filho JC, Álvarez JM, Lassounskaia E, Borges da Silva H, D'Império-Lima MR., Free PMC Article | 12/6/2023 |
| Effects of experimental ulcerative colitis on myenteric neurons in P2X7-knockout mice. | Effects of experimental ulcerative colitis on myenteric neurons in P2X7-knockout mice.
Machado FA, Souza RF, Figliuolo VR, Coutinho-Silva R, Castelucci P. | 11/7/2023 |
| P2RX7 gene knockout or antagonism reduces angiotensin II-induced hypertension, vascular injury and immune cell activation. | P2RX7 gene knockout or antagonism reduces angiotensin II-induced hypertension, vascular injury and immune cell activation.
Shokoples BG, Berillo O, Comeau K, Chen HY, Higaki A, Caillon A, Ferreira NS, Engert JC, Thanassoulis G, Paradis P, Schiffrin EL. | 11/1/2023 |
| P2X7 Receptor in Microglia Contributes to Propofol-induced Unconsciousness by Regulating Synaptic Plasticity in Mice. | P2X7 Receptor in Microglia Contributes to Propofol-induced Unconsciousness by Regulating Synaptic Plasticity in Mice.
Zhang B, Zhang P, Li T, Cao Y, Chen T, Chen C, Zhang Z, Zhong Q. | 07/7/2023 |
| Study of the roles of caspase-3 and nuclear factor kappa B in myenteric neurons in a P2X7 receptor knockout mouse model of ulcerative colitis. | Study of the roles of caspase-3 and nuclear factor kappa B in myenteric neurons in a P2X7 receptor knockout mouse model of ulcerative colitis.
Magalhães HIR, Machado FA, Souza RF, Caetano MAF, Figliuolo VR, Coutinho-Silva R, Castelucci P., Free PMC Article | 07/5/2023 |
| The Pannexin 1 Channel and the P2X7 Receptor Are in Complex Interplay to Regulate the Release of Soluble Ectonucleotidases in the Murine Bladder Lamina Propria. | The Pannexin 1 Channel and the P2X7 Receptor Are in Complex Interplay to Regulate the Release of Soluble Ectonucleotidases in the Murine Bladder Lamina Propria.
Aresta Branco MSL, Gutierrez Cruz A, Peri LE, Mutafova-Yambolieva VN., Free PMC Article | 06/30/2023 |
| P2X7R/AKT/mTOR signaling mediates high glucose-induced decrease in podocyte autophagy. | P2X7R/AKT/mTOR signaling mediates high glucose-induced decrease in podocyte autophagy.
Qian C, Lu J, Che X, Min L, Wang M, Song A, Lu R, Gu L, Xie K. | 06/22/2023 |
| The P2X7 receptor contributes to seizures and inflammation-driven long-lasting brain hyperexcitability following hypoxia in neonatal mice. | The P2X7 receptor contributes to seizures and inflammation-driven long-lasting brain hyperexcitability following hypoxia in neonatal mice.
Smith J, Menéndez Méndez A, Alves M, Parras A, Conte G, Bhattacharya A, Ceusters M, Nicke A, Henshall DC, Jimenez-Mateos EM, Engel T. | 06/7/2023 |
| P2X7 receptor of microglia in olfactory bulb mediates the pathogenesis of olfactory dysfunction in a mouse model of allergic rhinitis. | P2X7 receptor of microglia in olfactory bulb mediates the pathogenesis of olfactory dysfunction in a mouse model of allergic rhinitis.
Ren C, Mou YK, Song XY, Wei SZ, Wang HR, Wang Y, Zhang WB, Li B, Song XC. | 05/15/2023 |
| P2RX7 signaling drives the differentiation of Th1 cells through metabolic reprogramming for aerobic glycolysis. | P2RX7 signaling drives the differentiation of Th1 cells through metabolic reprogramming for aerobic glycolysis.
de Salles ÉM, Raeder PL, Angeli CB, Santiago VF, de Souza CN, Ramalho T, Câmara NOS, Palmisano G, Álvarez JM, D'Império Lima MR., Free PMC Article | 04/12/2023 |
| Mitochondrial P2X7 Receptor Localization Modulates Energy Metabolism Enhancing Physical Performance. | Mitochondrial P2X7 Receptor Localization Modulates Energy Metabolism Enhancing Physical Performance.
Sarti AC, Vultaggio-Poma V, Falzoni S, Missiroli S, Giuliani AL, Boldrini P, Bonora M, Faita F, Di Lascio N, Kusmic C, Solini A, Novello S, Morari M, Rossato M, Wieckowski MR, Giorgi C, Pinton P, Di Virgilio F., Free PMC Article | 02/10/2023 |