Regulatory T Cell Insufficiency in Autoimmune Diabetes Is Driven by Selective Loss of Neuropilin-1 on Intraislet Regulatory T Cells. | Regulatory T Cell Insufficiency in Autoimmune Diabetes Is Driven by Selective Loss of Neuropilin-1 on Intraislet Regulatory T Cells. Grebinoski S, Pieklo G, Zhang Q, Visperas A, Cui J, Goulet J, Xiao H, Brunazzi EA, Cardello C, Herrada AA, Das J, Workman CJ, Vignali DAA., | 09/11/2024 |
Dnmt3a1 regulates hippocampus-dependent memory via the downstream target Nrp1. | Dnmt3a1 regulates hippocampus-dependent memory via the downstream target Nrp1. Kupke J, Klimmt J, Mudlaff F, Schwab M, Lutsik P, Plass C, Sticht C, Oliveira AMM., Free PMC Article | 08/27/2024 |
Targeting the transmembrane cytokine co-receptor neuropilin-1 in distal tubules improves renal injury and fibrosis. | Targeting the transmembrane cytokine co-receptor neuropilin-1 in distal tubules improves renal injury and fibrosis. Li Y, Wang Z, Xu H, Hong Y, Shi M, Hu B, Wang X, Ma S, Wang M, Cao C, Zhu H, Hu D, Xu C, Lin Y, Xu G, Yao Y, Zeng R., Free PMC Article | 08/2/2024 |
NRP1 is a receptor for mammalian orthoreovirus engaged by distinct capsid subunits. | NRP1 is a receptor for mammalian orthoreovirus engaged by distinct capsid subunits. Shang P, Dos Santos Natividade R, Taylor GM, Ray A, Welsh OL, Fiske KL, Sutherland DM, Alsteens D, Dermody TS., | 06/27/2024 |
A proteomics approach to isolating neuropilin-dependent alpha5 integrin trafficking pathways: neuropilin 1 and 2 co-traffic alpha5 integrin through endosomal p120RasGAP to promote polarised fibronectin fibrillogenesis in endothelial cells. | A proteomics approach to isolating neuropilin-dependent α5 integrin trafficking pathways: neuropilin 1 and 2 co-traffic α5 integrin through endosomal p120RasGAP to promote polarised fibronectin fibrillogenesis in endothelial cells. Benwell CJ, Johnson RT, Taylor JAGE, Lambert J, Robinson SD., Free PMC Article | 06/12/2024 |
Neuropilin-1 regulates renin synthesis in juxtaglomerular cells. | Neuropilin-1 regulates renin synthesis in juxtaglomerular cells. Shen Y, Lotenberg K, Zaworski J, Broeker KA, Vasseur F, Louedec L, Placier S, Frère P, Verpont MC, Galichon P, Buob D, Hadchouel J, Terzi F, Chatziantoniou C, Calmont A. | 05/9/2024 |
Mesenchymal stem cell-derived extracellular vesicles exert pro-angiogenic and pro-lymphangiogenic effects in ischemic tissues by transferring various microRNAs and proteins including ITGa5 and NRP1. | Mesenchymal stem cell-derived extracellular vesicles exert pro-angiogenic and pro-lymphangiogenic effects in ischemic tissues by transferring various microRNAs and proteins including ITGa5 and NRP1. Łabędź-Masłowska A, Vergori L, Kędracka-Krok S, Karnas E, Bobis-Wozowicz S, Sekuła-Stryjewska M, Sarna M, Andriantsitohaina R, Zuba-Surma EK., Free PMC Article | 02/20/2024 |
NRP1 interacts with endoglin and VEGFR2 to modulate VEGF signaling and endothelial cell sprouting. | NRP1 interacts with endoglin and VEGFR2 to modulate VEGF signaling and endothelial cell sprouting. Sharma S, Ehrlich M, Zhang M, Blobe GC, Henis YI., Free PMC Article | 01/30/2024 |
Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections. | Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections. Abberger H, Hose M, Ninnemann A, Menne C, Eilbrecht M, Lang KS, Matuschewski K, Geffers R, Herz J, Buer J, Westendorf AM, Hansen W., Free PMC Article | 12/21/2023 |
Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4[+] T cells. | Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4(+) T cells. Sandoval S, Malany K, Thongphanh K, Martinez CA, Goodson ML, Souza FDC, Lin LW, Sweeney N, Pennington J, Lein PJ, Kerkvliet NI, Ehrlich AK., Free PMC Article | 12/5/2023 |
Infection of liver sinusoidal endothelial cells with Muromegalovirus muridbeta1 involves binding to neuropilin-1 and is dynamin-dependent. | Infection of liver sinusoidal endothelial cells with Muromegalovirus muridbeta1 involves binding to neuropilin-1 and is dynamin-dependent. Kyrrestad I, Larsen AK, Sánchez Romano J, Simón-Santamaría J, Li R, Sørensen KK., Free PMC Article | 12/4/2023 |
Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis. | Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis. Benwell CJ, Johnson RT, Taylor JAGE, Price CA, Robinson SD., Free PMC Article | 08/1/2023 |
Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow. | Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow. Bosseboeuf E, Chikh A, Chaker AB, Mitchell TP, Vignaraja D, Rajendrakumar R, Khambata RS, Nightingale TD, Mason JC, Randi AM, Ahluwalia A, Raimondi C., Free PMC Article | 05/31/2023 |
USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells. | USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells. Zhao J, Bai J, Peng F, Qiu C, Li Y, Zhong L., Free PMC Article | 01/28/2023 |
Neuropilin-1 Facilitates Pseudorabies Virus Replication and Viral Glycoprotein B Promotes Its Degradation in a Furin-Dependent Manner. | Neuropilin-1 Facilitates Pseudorabies Virus Replication and Viral Glycoprotein B Promotes Its Degradation in a Furin-Dependent Manner. Chen M, Wang MH, Shen XG, Liu H, Zhang YY, Peng JM, Meng F, Wang TY, Bai YZ, Sun MX, Tian ZJ, Yin X, Cai XH, Tang YD., Free PMC Article | 11/5/2022 |
Neuropilin-1 (NRP1) expression distinguishes self-reactive helper T cells in systemic autoimmune disease. | Neuropilin-1 (NRP1) expression distinguishes self-reactive helper T cells in systemic autoimmune disease. Raveney BJ, El-Darawish Y, Sato W, Arinuma Y, Yamaoka K, Hori S, Yamamura T, Oki S., Free PMC Article | 10/15/2022 |
Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability. | Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability. Gioelli N, Neilson LJ, Wei N, Villari G, Chen W, Kuhle B, Ehling M, Maione F, Willox S, Brundu S, Avanzato D, Koulouras G, Mazzone M, Giraudo E, Yang XL, Valdembri D, Zanivan S, Serini G., Free PMC Article | 07/30/2022 |
Neuropilin-1 Identifies a New Subpopulation of TGF-beta-Induced Foxp3(+) Regulatory T Cells With Potent Suppressive Function and Enhanced Stability During Inflammation. | Neuropilin-1 Identifies a New Subpopulation of TGF-β-Induced Foxp3(+) Regulatory T Cells With Potent Suppressive Function and Enhanced Stability During Inflammation. Chen W, Huang W, Xue Y, Chen Y, Qian W, Ma J, August A, Wang J, Zheng SG, Lin J., Free PMC Article | 05/28/2022 |
Neuropilin-1 deficiency in vascular smooth muscle cells is associated with hereditary hemorrhagic telangiectasia arteriovenous malformations. | Neuropilin-1 deficiency in vascular smooth muscle cells is associated with hereditary hemorrhagic telangiectasia arteriovenous malformations. Kilari S, Wang Y, Singh A, Graham RP, Iyer V, Thompson SM, Torbenson MS, Mukhopadhyay D, Misra S., Free PMC Article | 05/14/2022 |
The contribution of neuropilin-1 in the stability of CD4(+) CD25(+) regulatory T cells through the TGF-beta1/Smads signaling pathway in the presence of lipopolysaccharides. | The contribution of neuropilin-1 in the stability of CD4(+) CD25(+) regulatory T cells through the TGF-β1/Smads signaling pathway in the presence of lipopolysaccharides. Gao Y, Zhang X, Wang Z, Qiu Y, Liu Y, Shou S, Chai Y., Free PMC Article | 04/9/2022 |
Role of Nrp1 in controlling cortical inter-hemispheric circuits. | Role of Nrp1 in controlling cortical inter-hemispheric circuits. Martín-Fernández F, Bermejo-Santos A, Bragg-Gonzalo L, Briz CG, Serrano-Saiz E, Nieto M., Free PMC Article | 03/19/2022 |
Semaphorin 3A mitigates lipopolysaccharide-induced chondrocyte inflammation, apoptosis and extracellular matrix degradation by binding to Neuropilin-1. | Semaphorin 3A mitigates lipopolysaccharide-induced chondrocyte inflammation, apoptosis and extracellular matrix degradation by binding to Neuropilin-1. Zhang H, Lu Y, Wu B, Xia F., Free PMC Article | 02/19/2022 |
Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution. | Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution. Termini CM, Pang A, Fang T, Roos M, Chang VY, Zhang Y, Setiawan NJ, Signaevskaia L, Li M, Kim MM, Tabibi O, Lin PK, Sasine JP, Chatterjee A, Murali R, Himburg HA, Chute JP., Free PMC Article | 01/8/2022 |
Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity. | Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity. Diaz-Marin R, Crespo-Garcia S, Wilson AM, Buscarlet M, Dejda A, Fournier F, Juneau R, Alquier T, Sapieha P., Free PMC Article | 11/13/2021 |
miR-128-3p Inhibits NRP1 Expression and Promotes Inflammatory Response to Acute Kidney Injury in Sepsis. | miR-128-3p Inhibits NRP1 Expression and Promotes Inflammatory Response to Acute Kidney Injury in Sepsis. Wang L, Wang K, Tian Z. | 07/17/2021 |