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    Nrp1 neuropilin 1 [ Mus musculus (house mouse) ]

    Gene ID: 18186, updated on 28-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Regulatory T Cell Insufficiency in Autoimmune Diabetes Is Driven by Selective Loss of Neuropilin-1 on Intraislet Regulatory T Cells.

    Regulatory T Cell Insufficiency in Autoimmune Diabetes Is Driven by Selective Loss of Neuropilin-1 on Intraislet Regulatory T Cells.
    Grebinoski S, Pieklo G, Zhang Q, Visperas A, Cui J, Goulet J, Xiao H, Brunazzi EA, Cardello C, Herrada AA, Das J, Workman CJ, Vignali DAA.,

    09/11/2024
    Dnmt3a1 regulates hippocampus-dependent memory via the downstream target Nrp1.

    Dnmt3a1 regulates hippocampus-dependent memory via the downstream target Nrp1.
    Kupke J, Klimmt J, Mudlaff F, Schwab M, Lutsik P, Plass C, Sticht C, Oliveira AMM., Free PMC Article

    08/27/2024
    Targeting the transmembrane cytokine co-receptor neuropilin-1 in distal tubules improves renal injury and fibrosis.

    Targeting the transmembrane cytokine co-receptor neuropilin-1 in distal tubules improves renal injury and fibrosis.
    Li Y, Wang Z, Xu H, Hong Y, Shi M, Hu B, Wang X, Ma S, Wang M, Cao C, Zhu H, Hu D, Xu C, Lin Y, Xu G, Yao Y, Zeng R., Free PMC Article

    08/2/2024
    NRP1 is a receptor for mammalian orthoreovirus engaged by distinct capsid subunits.

    NRP1 is a receptor for mammalian orthoreovirus engaged by distinct capsid subunits.
    Shang P, Dos Santos Natividade R, Taylor GM, Ray A, Welsh OL, Fiske KL, Sutherland DM, Alsteens D, Dermody TS.,

    06/27/2024
    A proteomics approach to isolating neuropilin-dependent alpha5 integrin trafficking pathways: neuropilin 1 and 2 co-traffic alpha5 integrin through endosomal p120RasGAP to promote polarised fibronectin fibrillogenesis in endothelial cells.

    A proteomics approach to isolating neuropilin-dependent α5 integrin trafficking pathways: neuropilin 1 and 2 co-traffic α5 integrin through endosomal p120RasGAP to promote polarised fibronectin fibrillogenesis in endothelial cells.
    Benwell CJ, Johnson RT, Taylor JAGE, Lambert J, Robinson SD., Free PMC Article

    06/12/2024
    Neuropilin-1 regulates renin synthesis in juxtaglomerular cells.

    Neuropilin-1 regulates renin synthesis in juxtaglomerular cells.
    Shen Y, Lotenberg K, Zaworski J, Broeker KA, Vasseur F, Louedec L, Placier S, Frère P, Verpont MC, Galichon P, Buob D, Hadchouel J, Terzi F, Chatziantoniou C, Calmont A.

    05/9/2024
    Mesenchymal stem cell-derived extracellular vesicles exert pro-angiogenic and pro-lymphangiogenic effects in ischemic tissues by transferring various microRNAs and proteins including ITGa5 and NRP1.

    Mesenchymal stem cell-derived extracellular vesicles exert pro-angiogenic and pro-lymphangiogenic effects in ischemic tissues by transferring various microRNAs and proteins including ITGa5 and NRP1.
    Łabędź-Masłowska A, Vergori L, Kędracka-Krok S, Karnas E, Bobis-Wozowicz S, Sekuła-Stryjewska M, Sarna M, Andriantsitohaina R, Zuba-Surma EK., Free PMC Article

    02/20/2024
    NRP1 interacts with endoglin and VEGFR2 to modulate VEGF signaling and endothelial cell sprouting.

    NRP1 interacts with endoglin and VEGFR2 to modulate VEGF signaling and endothelial cell sprouting.
    Sharma S, Ehrlich M, Zhang M, Blobe GC, Henis YI., Free PMC Article

    01/30/2024
    Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections.

    Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections.
    Abberger H, Hose M, Ninnemann A, Menne C, Eilbrecht M, Lang KS, Matuschewski K, Geffers R, Herz J, Buer J, Westendorf AM, Hansen W., Free PMC Article

    12/21/2023
    Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4[+] T cells.

    Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4(+) T cells.
    Sandoval S, Malany K, Thongphanh K, Martinez CA, Goodson ML, Souza FDC, Lin LW, Sweeney N, Pennington J, Lein PJ, Kerkvliet NI, Ehrlich AK., Free PMC Article

    12/5/2023
    Infection of liver sinusoidal endothelial cells with Muromegalovirus muridbeta1 involves binding to neuropilin-1 and is dynamin-dependent.

    Infection of liver sinusoidal endothelial cells with Muromegalovirus muridbeta1 involves binding to neuropilin-1 and is dynamin-dependent.
    Kyrrestad I, Larsen AK, Sánchez Romano J, Simón-Santamaría J, Li R, Sørensen KK., Free PMC Article

    12/4/2023
    Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis.

    Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis.
    Benwell CJ, Johnson RT, Taylor JAGE, Price CA, Robinson SD., Free PMC Article

    08/1/2023
    Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow.

    Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow.
    Bosseboeuf E, Chikh A, Chaker AB, Mitchell TP, Vignaraja D, Rajendrakumar R, Khambata RS, Nightingale TD, Mason JC, Randi AM, Ahluwalia A, Raimondi C., Free PMC Article

    05/31/2023
    USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells.

    USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells.
    Zhao J, Bai J, Peng F, Qiu C, Li Y, Zhong L., Free PMC Article

    01/28/2023
    Neuropilin-1 Facilitates Pseudorabies Virus Replication and Viral Glycoprotein B Promotes Its Degradation in a Furin-Dependent Manner.

    Neuropilin-1 Facilitates Pseudorabies Virus Replication and Viral Glycoprotein B Promotes Its Degradation in a Furin-Dependent Manner.
    Chen M, Wang MH, Shen XG, Liu H, Zhang YY, Peng JM, Meng F, Wang TY, Bai YZ, Sun MX, Tian ZJ, Yin X, Cai XH, Tang YD., Free PMC Article

    11/5/2022
    Neuropilin-1 (NRP1) expression distinguishes self-reactive helper T cells in systemic autoimmune disease.

    Neuropilin-1 (NRP1) expression distinguishes self-reactive helper T cells in systemic autoimmune disease.
    Raveney BJ, El-Darawish Y, Sato W, Arinuma Y, Yamaoka K, Hori S, Yamamura T, Oki S., Free PMC Article

    10/15/2022
    Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability.

    Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability.
    Gioelli N, Neilson LJ, Wei N, Villari G, Chen W, Kuhle B, Ehling M, Maione F, Willox S, Brundu S, Avanzato D, Koulouras G, Mazzone M, Giraudo E, Yang XL, Valdembri D, Zanivan S, Serini G., Free PMC Article

    07/30/2022
    Neuropilin-1 Identifies a New Subpopulation of TGF-beta-Induced Foxp3(+) Regulatory T Cells With Potent Suppressive Function and Enhanced Stability During Inflammation.

    Neuropilin-1 Identifies a New Subpopulation of TGF-β-Induced Foxp3(+) Regulatory T Cells With Potent Suppressive Function and Enhanced Stability During Inflammation.
    Chen W, Huang W, Xue Y, Chen Y, Qian W, Ma J, August A, Wang J, Zheng SG, Lin J., Free PMC Article

    05/28/2022
    Neuropilin-1 deficiency in vascular smooth muscle cells is associated with hereditary hemorrhagic telangiectasia arteriovenous malformations.

    Neuropilin-1 deficiency in vascular smooth muscle cells is associated with hereditary hemorrhagic telangiectasia arteriovenous malformations.
    Kilari S, Wang Y, Singh A, Graham RP, Iyer V, Thompson SM, Torbenson MS, Mukhopadhyay D, Misra S., Free PMC Article

    05/14/2022
    The contribution of neuropilin-1 in the stability of CD4(+) CD25(+) regulatory T cells through the TGF-beta1/Smads signaling pathway in the presence of lipopolysaccharides.

    The contribution of neuropilin-1 in the stability of CD4(+) CD25(+) regulatory T cells through the TGF-β1/Smads signaling pathway in the presence of lipopolysaccharides.
    Gao Y, Zhang X, Wang Z, Qiu Y, Liu Y, Shou S, Chai Y., Free PMC Article

    04/9/2022
    Role of Nrp1 in controlling cortical inter-hemispheric circuits.

    Role of Nrp1 in controlling cortical inter-hemispheric circuits.
    Martín-Fernández F, Bermejo-Santos A, Bragg-Gonzalo L, Briz CG, Serrano-Saiz E, Nieto M., Free PMC Article

    03/19/2022
    Semaphorin 3A mitigates lipopolysaccharide-induced chondrocyte inflammation, apoptosis and extracellular matrix degradation by binding to Neuropilin-1.

    Semaphorin 3A mitigates lipopolysaccharide-induced chondrocyte inflammation, apoptosis and extracellular matrix degradation by binding to Neuropilin-1.
    Zhang H, Lu Y, Wu B, Xia F., Free PMC Article

    02/19/2022
    Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution.

    Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution.
    Termini CM, Pang A, Fang T, Roos M, Chang VY, Zhang Y, Setiawan NJ, Signaevskaia L, Li M, Kim MM, Tabibi O, Lin PK, Sasine JP, Chatterjee A, Murali R, Himburg HA, Chute JP., Free PMC Article

    01/8/2022
    Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity.

    Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity.
    Diaz-Marin R, Crespo-Garcia S, Wilson AM, Buscarlet M, Dejda A, Fournier F, Juneau R, Alquier T, Sapieha P., Free PMC Article

    11/13/2021
    miR-128-3p Inhibits NRP1 Expression and Promotes Inflammatory Response to Acute Kidney Injury in Sepsis.

    miR-128-3p Inhibits NRP1 Expression and Promotes Inflammatory Response to Acute Kidney Injury in Sepsis.
    Wang L, Wang K, Tian Z.

    07/17/2021
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