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    DRD2 dopamine receptor D2 [ Homo sapiens (human) ]

    Gene ID: 1813, updated on 10-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    A shared spatial topography links the functional connectome correlates of cocaine use disorder and dopamine D2/3 receptor densities.

    A shared spatial topography links the functional connectome correlates of cocaine use disorder and dopamine D(2/3) receptor densities.
    Ricard JA, Labache L, Segal A, Dhamala E, Cocuzza CV, Jones G, Yip SW, Chopra S, Holmes AJ., Free PMC Article

    09/25/2024
    Comparison of the function of two novel human dopamine D2 receptor variants identifies a likely mechanism for their pathogenicity.

    Comparison of the function of two novel human dopamine D2 receptor variants identifies a likely mechanism for their pathogenicity.
    Rodriguez-Contreras D, García-Nafría J, Chan AE, Shinde U, Neve KA.,

    09/25/2024
    DRD2 activation inhibits choroidal neovascularization in patients with Parkinson's disease and age-related macular degeneration.

    DRD2 activation inhibits choroidal neovascularization in patients with Parkinson's disease and age-related macular degeneration.
    Mathis T, Baudin F, Mariet AS, Augustin S, Bricout M, Przegralek L, Roubeix C, Benzenine É, Blot G, Nous C, Kodjikian L, Mauget-Faÿsse M, Sahel JA, Plevin R, Zeitz C, Delarasse C, Guillonneau X, Creuzot-Garcher C, Quantin C, Hunot S, Sennlaub F., Free PMC Article

    09/13/2024
    Receptor density influences ligand-induced dopamine D2L receptor homodimerization.

    Receptor density influences ligand-induced dopamine D(2L) receptor homodimerization.
    Ferraiolo M, Atik H, Ponthot R, Belo do Nascimento I, Beckers P, Stove C, Hermans E.

    07/28/2024
    The influence of hippocampal dopamine D2 receptor losses on episodic-memory decline across 5 years is moderated by BDNF and KIBRA polymorphisms.

    The influence of hippocampal dopamine D2 receptor losses on episodic-memory decline across 5 years is moderated by BDNF and KIBRA polymorphisms.
    Papenberg G, Karalija N, Johansson J, Andersson M, Axelsson J, Riklund K, Lindenberger U, Nyberg L, Bäckman L.

    06/18/2024
    DRD2 TaqIA polymorphism-related functional connectivity between anterior insula and dorsolateral prefrontal cortex predicts the retention time in heroin-dependent individuals under methadone maintenance treatment.

    DRD2 TaqIA polymorphism-related functional connectivity between anterior insula and dorsolateral prefrontal cortex predicts the retention time in heroin-dependent individuals under methadone maintenance treatment.
    Qin Y, Sun Q, Wang L, Hu F, Zhang Q, Wang W, Li W, Wang Y.

    03/12/2024
    Subcutaneous adipose tissue dopamine D2 receptor is increased in prediabetes and T2D.

    Subcutaneous adipose tissue dopamine D2 receptor is increased in prediabetes and T2D.
    Vranic M, Ahmed F, Kristófi R, Hetty S, Mokhtari D, Svensson MK, Eriksson JW, Pereira MJ., Free PMC Article

    02/8/2024
    Gene Interaction of Dopaminergic Synaptic Pathway Genes in Attention-Deficit Hyperactivity Disorder: a Case-Control Study in Chinese Children.

    Gene Interaction of Dopaminergic Synaptic Pathway Genes in Attention-Deficit Hyperactivity Disorder: a Case-Control Study in Chinese Children.
    Zhong L, He H, Zhang J, Gao X, Yin F, Zuo P, Song R., Free PMC Article

    01/17/2024
    A dopamine receptor D2 genetic polymorphism associated with transition to mental disorders in a cohort of individuals with at-risk mental state for psychosis.

    A dopamine receptor D2 genetic polymorphism associated with transition to mental disorders in a cohort of individuals with at-risk mental state for psychosis.
    Marques JH, Talib LL, Hortêncio L, Andrade JC, Alves TM, Serpa MH, Yamamoto GL, van de Bilt MT, Rössler W, Gattaz WF, Loch AA., Free PMC Article

    12/1/2023
    Hypomethylation of DRD2 promotes breast cancer through the FLNA-ERK pathway.

    Hypomethylation of DRD2 promotes breast cancer through the FLNA-ERK pathway.
    Zhang S, Zhong M, Zhu H, You Q, Yuan H, Li Y.

    11/20/2023
    Association of DRD2, DRD4 and COMT genes variants and their gene-gene interactions with antipsychotic treatment response in patients with schizophrenia.

    Association of DRD2, DRD4 and COMT genes variants and their gene-gene interactions with antipsychotic treatment response in patients with schizophrenia.
    Taheri N, Pirboveiri R, Sayyah M, Bijanzadeh M, Ghandil P., Free PMC Article

    11/14/2023
    G Protein-Coupled Receptor Kinase 2 Selectively Enhances beta-Arrestin Recruitment to the D2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation.

    G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D(2) Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation.
    Sánchez-Soto M, Boldizsar NM, Schardien KA, Madaras NS, Willette BKA, Inbody LR, Dasaro C, Moritz AE, Drube J, Haider RS, Free RB, Hoffman C, Sibley DR., Free PMC Article

    11/2/2023
    Striatal dopamine D2 receptor availability as a predictor of subsequent alcohol use in social drinkers.

    Striatal dopamine D2 receptor availability as a predictor of subsequent alcohol use in social drinkers.
    Jangard S, Jayaram-Lindström N, Isacsson NH, Matheson GJ, Plavén-Sigray P, Franck J, Borg J, Farde L, Cervenka S.

    10/28/2023
    Comparing DRD2 Promoter Methylation Between Blood and Brain in Alcohol Dependence.

    Comparing DRD2 Promoter Methylation Between Blood and Brain in Alcohol Dependence.
    Arfmann W, Achenbach J, Meyer-Bockenkamp F, Proskynitopoulos PJ, Groh A, Muschler MAN, Glahn A, Hagemeier L, Preuss V, Klintschar M, Frieling H, Rhein M.

    10/20/2023
    Linkage and association of variants in the dopamine receptor 2 gene (DRD2) with polycystic ovary syndrome.

    Linkage and association of variants in the dopamine receptor 2 gene (DRD2) with polycystic ovary syndrome.
    Amin M, Horst N, Gragnoli C., Free PMC Article

    08/16/2023
    The Addiction-Susceptibility TaqIA/Ankk1 Controls Reward and Metabolism Through D2 Receptor-Expressing Neurons.

    The Addiction-Susceptibility TaqIA/Ankk1 Controls Reward and Metabolism Through D(2) Receptor-Expressing Neurons.
    Montalban E, Walle R, Castel J, Ansoult A, Hassouna R, Foppen E, Fang X, Hutelin Z, Mickus S, Perszyk E, Petitbon A, Berthelet J, Rodrigues-Lima F, Cebrian-Serrano A, Gangarossa G, Martin C, Trifilieff P, Bosch-Bouju C, Small DM, Luquet S.

    08/11/2023
    [Influence of rs2587552 polymorphism of DRD2 gene on the effect of a childhood obesity intervention: A prospective, parallel-group controlled trial].

    [Influence of rs2587552 polymorphism of DRD2 gene on the effect of a childhood obesity intervention: A prospective, parallel-group controlled trial].
    Chen J, Xiao WC, Shan R, Song JY, Liu Z., Free PMC Article

    06/21/2023
    The ANKK1/DRD2 gene TaqIA polymorphism (rs1800497) is associated with the severity of extrapyramidal side effects of haloperidol treatment in CYP2D6 extensive metabolizers with schizophrenia spectrum disorders.

    The ANKK1/DRD2 gene TaqIA polymorphism (rs1800497) is associated with the severity of extrapyramidal side effects of haloperidol treatment in CYP2D6 extensive metabolizers with schizophrenia spectrum disorders.
    Kibitov AA, Kiryanova EM, Salnikova LI, Bure IV, Shmukler AB, Kibitov AO.

    06/16/2023
    Alpha-2-Macroglobulin (A2M) and Dopamine Receptor D2 (DRD2) expression analysis and Influence of Separation from Parents in Childhood on the Suicide and Self-injury Behavior and Psychological Adjustment in Adolescence.

    Alpha-2-Macroglobulin (A2M) and Dopamine Receptor D2 (DRD2) expression analysis and Influence of Separation from Parents in Childhood on the Suicide and Self-injury Behavior and Psychological Adjustment in Adolescence.
    Xu Q, Xu H, Li S.

    05/25/2023
    Dopamine receptor D2 regulates glioblastoma survival and death through MET and death receptor 4/5.

    Dopamine receptor D2 regulates glioblastoma survival and death through MET and death receptor 4/5.
    Jeon HM, Oh YT, Shin YJ, Chang N, Kim D, Woo D, Yeup Y, Joo KM, Jo H, Yang H, Lee JK, Kang W, Sa J, Lee WJ, Hale J, Lathia JD, Purow B, Park MJ, Park JB, Nam DH, Lee J., Free PMC Article

    04/12/2023
    Assessment of genetic variants in D2 dopamine receptor (DRD2) gene as risk factors for post-traumatic stress disorder (PTSD) and major depressive disorder (MDD): A systematic review and meta-analysis.

    Assessment of genetic variants in D2 dopamine receptor (DRD2) gene as risk factors for post-traumatic stress disorder (PTSD) and major depressive disorder (MDD): A systematic review and meta-analysis.
    Zhang X, Han Y, Liu X, Chen J, Yuan Z, Wang Y.

    03/15/2023
    Gait Abnormalities and Aberrant D2 Receptor Expression and Signaling in Mice Carrying the Human Pathogenic Mutation DRD2[I212F].

    Gait Abnormalities and Aberrant D2 Receptor Expression and Signaling in Mice Carrying the Human Pathogenic Mutation DRD2(I212F).
    Rodriguez-Contreras D, Gong S, Lebowitz JJ, Fedorov LM, Asad N, Dore TM, Phillips TJ, Ford CP, Williams JT, Neve KA., Free PMC Article

    02/27/2023
    Associated and intermediate factors between genetic variants of the dopaminergic D2 receptor gene and harmful alcohol use in young adults.

    Associated and intermediate factors between genetic variants of the dopaminergic D2 receptor gene and harmful alcohol use in young adults.
    Mattioni J, Vansteene C, Poupon D, Gorwood P, Ramoz N., Free PMC Article

    02/27/2023
    Impact on the Risk and Severity of Childhood Onset Schizophrenia of Schizophrenia Risk Genetic Variants at the DRD2 and ZNF804A Loci.

    Impact on the Risk and Severity of Childhood Onset Schizophrenia of Schizophrenia Risk Genetic Variants at the DRD2 and ZNF804A Loci.
    Alfimova MV, Nikitina SG, Lezheiko TV, Simashkova NV, Golimbet VE.

    02/11/2023
    The DRD2 Taq1A polymorphism moderates the effect of PTSD symptom severity on the left hippocampal CA3 volume: a pilot study.

    The DRD2 Taq1A polymorphism moderates the effect of PTSD symptom severity on the left hippocampal CA3 volume: a pilot study.
    Yuan M, Zhu H, Li Y, Ge F, Lui S, Gong Q, Qiu C, Song H, Zhang W., Free PMC Article

    10/29/2022
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