| Notch2 controls developmental fate choices between germinal center and marginal zone B cells upon immunization. | Notch2 controls developmental fate choices between germinal center and marginal zone B cells upon immunization.
Babushku T, Lechner M, Ehrenberg S, Rambold U, Schmidt-Supprian M, Yates AJ, Rane S, Zimber-Strobl U, Strobl LJ., Free PMC Article | 03/6/2024 |
| NOTCH2 promotes osteoclast maturation and metabolism and modulates the transcriptome profile during osteoclastogenesis. | NOTCH2 promotes osteoclast maturation and metabolism and modulates the transcriptome profile during osteoclastogenesis.
Canalis E, Schilling L, Yu J, Denker E., Free PMC Article | 02/28/2024 |
| NOTCH2 sensitizes the chondrocyte to the inflammatory response of tumor necrosis factor alpha. | NOTCH2 sensitizes the chondrocyte to the inflammatory response of tumor necrosis factor α.
Canalis E, Yu J, Singh V, Mocarska M, Schilling L., Free PMC Article | 01/10/2024 |
| Long-term consequences of regulatory T-cell-specific knockout of Notch2 in immune homeostasis. | Long-term consequences of regulatory T-cell-specific knockout of Notch2 in immune homeostasis.
Fan HM, Qiao YL, Liu Y, Xu S, Ni HF, Jiao WE, Tao ZZ, Chen SM. | 11/3/2023 |
| Specific knockout of Notch2 in Treg cells significantly inhibits the growth and proliferation of head and neck squamous cell carcinoma in mice. | Specific knockout of Notch2 in Treg cells significantly inhibits the growth and proliferation of head and neck squamous cell carcinoma in mice.
Wei JH, Qiao YL, Xu S, Zou Y, Ni HF, Wu LZ, Tao ZZ, Jiao WE, Chen SM. | 09/27/2023 |
| The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell-mediated graft-versus-host disease. | The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell-mediated graft-versus-host disease.
Cheng Q, Wang D, Lai X, Liu Y, Zuo Y, Zhang W, Lei L, Chen J, Liu H, Wang Y, Liu H, Zheng H, Wu D, Xu Y. | 03/28/2023 |
| Expression of expanded GGC repeats within NOTCH2NLC causes behavioral deficits and neurodegeneration in a mouse model of neuronal intranuclear inclusion disease. | Expression of expanded GGC repeats within NOTCH2NLC causes behavioral deficits and neurodegeneration in a mouse model of neuronal intranuclear inclusion disease.
Liu Q, Zhang K, Kang Y, Li Y, Deng P, Li Y, Tian Y, Sun Q, Tang Y, Xu K, Zhou Y, Wang JL, Guo J, Li JD, Xia K, Meng Q, Allen EG, Wen Z, Li Z, Jiang H, Shen L, Duan R, Yao B, Tang B, Jin P, Pan Y., Free PMC Article | 12/3/2022 |
| Smooth Muscle Cell Notch2 Is Not Required for Atherosclerotic Plaque Formation in ApoE Null Mice. | Smooth Muscle Cell Notch2 Is Not Required for Atherosclerotic Plaque Formation in ApoE Null Mice.
Davis-Knowlton J, Turner JE, Harrington A, Liaw L., Free PMC Article | 10/29/2022 |
| The endothelial Dll4-muscular Notch2 axis regulates skeletal muscle mass. | The endothelial Dll4-muscular Notch2 axis regulates skeletal muscle mass.
Fujimaki S, Matsumoto T, Muramatsu M, Nagahisa H, Horii N, Seko D, Masuda S, Wang X, Asakura Y, Takahashi Y, Miyamoto Y, Usuki S, Yasunaga KI, Kamei Y, Nishinakamura R, Minami T, Fukuda T, Asakura A, Ono Y. | 04/30/2022 |
| Hairy and enhancer of split 1 is a primary effector of NOTCH2 signaling and induces osteoclast differentiation and function. | Hairy and enhancer of split 1 is a primary effector of NOTCH2 signaling and induces osteoclast differentiation and function.
Yu J, Schilling L, Eller T, Canalis E., Free PMC Article | 02/19/2022 |
| Uterine Notch2 facilitates pregnancy recognition and corpus luteum maintenance via upregulating decidual Prl8a2. | Uterine Notch2 facilitates pregnancy recognition and corpus luteum maintenance via upregulating decidual Prl8a2.
Bao H, Sun Y, Yang N, Deng N, Ni Z, Tang Y, Li G, Du L, Wang YL, Chen D, Wang H, Kong S., Free PMC Article | 12/11/2021 |
| Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation. | Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation.
Gaudette BT, Roman CJ, Ochoa TA, Gómez Atria D, Jones DD, Siebel CW, Maillard I, Allman D., Free PMC Article | 12/4/2021 |
| LncRNA SNHG16 promotes pulmonary fibrosis by targeting miR-455-3p to regulate the Notch2 pathway. | LncRNA SNHG16 promotes pulmonary fibrosis by targeting miR-455-3p to regulate the Notch2 pathway.
Liu P, Zhao L, Gu Y, Zhang M, Gao H, Meng Y., Free PMC Article | 10/30/2021 |
| Notch2 suppresses the development of allergic rhinitis by promoting FOXP3 expression and Treg cell differentiation. | Notch2 suppresses the development of allergic rhinitis by promoting FOXP3 expression and Treg cell differentiation.
Jiao WE, Sun L, Xu S, Deng YQ, Qiao YL, Xi Y, Tao ZZ, Chen SM. | 10/9/2021 |
| Notch-Regulated Dendritic Cells Restrain Inflammation-Associated Colorectal Carcinogenesis. | Notch-Regulated Dendritic Cells Restrain Inflammation-Associated Colorectal Carcinogenesis.
Wang L, Yu S, Chan ER, Chen KY, Liu C, Che D, Awadallah A, Myers J, Askew D, Huang AY, Maillard I, Huang D, Xin W, Zhou L., Free PMC Article | 07/31/2021 |
| Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development. | Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development.
Romero-Wolf M, Shin B, Zhou W, Koizumi M, Rothenberg EV, Hosokawa H., Free PMC Article | 03/27/2021 |
| Heterogeneity of Satellite Cells Implicates DELTA1/NOTCH2 Signaling in Self-Renewal. | Heterogeneity of Satellite Cells Implicates DELTA1/NOTCH2 Signaling in Self-Renewal.
Yartseva V, Goldstein LD, Rodman J, Kates L, Chen MZ, Chen YJ, Foreman O, Siebel CW, Modrusan Z, Peterson AS, Jovičić A. | 03/20/2021 |
| Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2. | Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2.
Kakuda S, LoPilato RK, Ito A, Haltiwanger RS., Free PMC Article | 03/13/2021 |
| Notch2-mediated plasticity between marginal zone and follicular B cells. | Notch2-mediated plasticity between marginal zone and follicular B cells.
Lechner M, Engleitner T, Babushku T, Schmidt-Supprian M, Rad R, Strobl LJ, Zimber-Strobl U., Free PMC Article | 03/6/2021 |
| Xylosyl Extension of O-Glucose Glycans on the Extracellular Domain of NOTCH1 and NOTCH2 Regulates Notch Cell Surface Trafficking. | Xylosyl Extension of O-Glucose Glycans on the Extracellular Domain of NOTCH1 and NOTCH2 Regulates Notch Cell Surface Trafficking.
Urata Y, Saiki W, Tsukamoto Y, Sago H, Hibi H, Okajima T, Takeuchi H., Free PMC Article | 02/27/2021 |
| Notch and TLR signaling coordinate monocyte cell fate and inflammation. | Notch and TLR signaling coordinate monocyte cell fate and inflammation.
Gamrekelashvili J, Kapanadze T, Sablotny S, Ratiu C, Dastagir K, Lochner M, Karbach S, Wenzel P, Sitnow A, Fleig S, Sparwasser T, Kalinke U, Holzmann B, Haller H, Limbourg FP., Free PMC Article | 02/13/2021 |
| TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells. | TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells.
Vanderkerken M, Maes B, Vandersarren L, Toussaint W, Deswarte K, Vanheerswynghels M, Pouliot P, Martens L, Van Gassen S, Arthur CM, Kirkling ME, Reizis B, Conrad D, Stowell S, Hammad H, Lambrecht BN., Free PMC Article | 01/23/2021 |
| ADAM10 mediates ectopic proximal tubule development and renal fibrosis through Notch signalling. | ADAM10 mediates ectopic proximal tubule development and renal fibrosis through Notch signalling.
Li B, Zhu C, Dong L, Qin J, Xiang W, Davidson AJ, Feng S, Wang Y, Shen X, Weng C, Wang C, Zhu T, Teng L, Wang J, Englert C, Chen J, Jiang H., Free PMC Article | 12/19/2020 |
| Antisense oligonucleotides targeting Notch2 ameliorate the osteopenic phenotype in a mouse model of Hajdu-Cheney syndrome. | Antisense oligonucleotides targeting Notch2 ameliorate the osteopenic phenotype in a mouse model of Hajdu-Cheney syndrome.
Canalis E, Grossman TR, Carrer M, Schilling L, Yu J., Free PMC Article | 12/12/2020 |
| Id4 Downstream of Notch2 Maintains Neural Stem Cell Quiescence in the Adult Hippocampus. | Id4 Downstream of Notch2 Maintains Neural Stem Cell Quiescence in the Adult Hippocampus.
Zhang R, Boareto M, Engler A, Louvi A, Giachino C, Iber D, Taylor V. | 09/12/2020 |