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    Nos3 nitric oxide synthase 3, endothelial cell [ Mus musculus (house mouse) ]

    Gene ID: 18127, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    C1q/Tumor Necrosis Factor-Related Protein-9 Is a Novel Vasculoprotective Cytokine That Restores High Glucose-Suppressed Endothelial Progenitor Cell Functions by Activating the Endothelial Nitric Oxide Synthase.

    C1q/Tumor Necrosis Factor-Related Protein-9 Is a Novel Vasculoprotective Cytokine That Restores High Glucose-Suppressed Endothelial Progenitor Cell Functions by Activating the Endothelial Nitric Oxide Synthase.
    Hu Q, Qu W, Zhang T, Feng J, Dong X, Nie R, Chen J, Wang X, Peng C, Ke X., Free PMC Article

    02/21/2024
    Lymphocyte-Specific Protein 1 Regulates Expression and Stability of Endothelial Nitric Oxide Synthase.

    Lymphocyte-Specific Protein 1 Regulates Expression and Stability of Endothelial Nitric Oxide Synthase.
    Smeir M, Chumala P, Katselis GS, Liu L., Free PMC Article

    02/12/2024
    GPR56 Promotes Diabetic Kidney Disease Through eNOS Regulation in Glomerular Endothelial Cells.

    GPR56 Promotes Diabetic Kidney Disease Through eNOS Regulation in Glomerular Endothelial Cells.
    Wu J, Wang Z, Cai M, Wang X, Lo B, Li Q, He JC, Lee K, Fu J., Free PMC Article

    02/1/2024
    SUMOylation and coupling of eNOS mediated by PIAS1 contribute to maintenance of vascular homeostasis.

    SUMOylation and coupling of eNOS mediated by PIAS1 contribute to maintenance of vascular homeostasis.
    Wang L, Zeng W, Wang C, Lu Y, Xiong X, Chen S, Huang Q, Yan F, Huang Q.

    01/31/2024
    eNOS plays essential roles in the developing heart and aorta linked to disruption of Notch signalling.

    eNOS plays essential roles in the developing heart and aorta linked to disruption of Notch signalling.
    Eley L, Richardson RV, Alqahtani A, Chaudhry B, Henderson DJ., Free PMC Article

    01/29/2024
    Deletion of adipocyte NOS3 potentiates high-fat diet-induced hypertension and vascular remodelling via chemerin.

    Deletion of adipocyte NOS3 potentiates high-fat diet-induced hypertension and vascular remodelling via chemerin.
    Man AWC, Zhou Y, Reifenberg G, Camp A, Münzel T, Daiber A, Xia N, Li H., Free PMC Article

    01/13/2024
    Effects of endothelial nitric oxide synthase on mouse arteriovenous fistula hemodynamics.

    Effects of endothelial nitric oxide synthase on mouse arteriovenous fistula hemodynamics.
    Baltazar S, Northrup H, Chang J, Somarathna M, Isayeva Waldrop T, Lee T, Shiu YT., Free PMC Article

    01/3/2024
    Endothelial lipid droplets suppress eNOS to link high fat consumption to blood pressure elevation.

    Endothelial lipid droplets suppress eNOS to link high fat consumption to blood pressure elevation.
    Kim B, Zhao W, Tang SY, Levin MG, Ibrahim A, Yang Y, Roberts E, Lai L, Li J, Assoian RK, FitzGerald GA, Arany Z., Free PMC Article

    12/22/2023
    TRPC6 Deletion Enhances eNOS Expression and Reduces LPS-Induced Acute Lung Injury.

    TRPC6 Deletion Enhances eNOS Expression and Reduces LPS-Induced Acute Lung Injury.
    Wang M, Zhang X, Guo J, Yang S, Yang F, Chen X., Free PMC Article

    12/20/2023
    Endothelial VEGFR2-PLCgamma signaling regulates vascular permeability and antitumor immunity through eNOS/Src.

    Endothelial VEGFR2-PLCγ signaling regulates vascular permeability and antitumor immunity through eNOS/Src.
    Sjöberg E, Melssen M, Richards M, Ding Y, Chanoca C, Chen D, Nwadozi E, Pal S, Love DT, Ninchoji T, Shibuya M, Simons M, Dimberg A, Claesson-Welsh L., Free PMC Article

    11/1/2023
    eNOS Regulates Lymphatic Valve Specification by Controlling beta-Catenin Signaling During Embryogenesis in Mice.

    eNOS Regulates Lymphatic Valve Specification by Controlling β-Catenin Signaling During Embryogenesis in Mice.
    Iyer D, Mastrogiacomo DM, Li K, Banerjee R, Yang Y, Scallan JP., Free PMC Article

    10/30/2023
    The importance of the endothelial nitric oxide synthase on the release of 6-nitrodopamine from mouse isolated atria and ventricles and their role on chronotropism.

    The importance of the endothelial nitric oxide synthase on the release of 6-nitrodopamine from mouse isolated atria and ventricles and their role on chronotropism.
    Britto-Júnior J, Pereira do Prado GL, Chiavegatto S, Cunha F, Moraes MO, Elisabete A Moraes M, Monica FZ, Antunes E, De Nucci G.

    09/19/2023
    Induction of KLF2 by Exercise Activates eNOS to Improve Vasodilatation in Diabetic Mice.

    Induction of KLF2 by Exercise Activates eNOS to Improve Vasodilatation in Diabetic Mice.
    Luo JY, Cheng CK, Gou L, He L, Zhao L, Zhang Y, Wang L, Lau CW, Xu A, Chen AF, Huang Y.

    08/25/2023
    Nitric oxide synthase and reduced arterial tone contribute to arteriovenous malformation.

    Nitric oxide synthase and reduced arterial tone contribute to arteriovenous malformation.
    Huang L, Cheng F, Zhang X, Zielonka J, Nystoriak MA, Xiang W, Raygor K, Wang S, Lakshmanan A, Jiang W, Yuan S, Hou KS, Zhang J, Wang X, Syed AU, Juric M, Takahashi T, Navedo MF, Wang RA., Free PMC Article

    08/23/2023
    Endothelial NOX4 aggravates eNOS uncoupling by decreasing dihydrofolate reductase after subarachnoid hemorrhage.

    Endothelial NOX4 aggravates eNOS uncoupling by decreasing dihydrofolate reductase after subarachnoid hemorrhage.
    Gao SQ, Shi JJ, Xue-Wang, Miao SH, Li T, Gao CC, Han YL, Qiu JY, Zhuang YS, Zhou ML.

    12/10/2022
    Regulation of endothelial nitric oxide synthase in cardiac remodeling.

    Regulation of endothelial nitric oxide synthase in cardiac remodeling.
    Musicante M, Kim HH, Chen Y, Liao F, Bhattacharya SK, Lu L, Sun Y.

    08/13/2022
    Partial Endothelial Nitric Oxide Synthase Deficiency Exacerbates Cognitive Deficit and Amyloid Pathology in the APPswe/PS1DeltaE9 Mouse Model of Alzheimer's Disease.

    Partial Endothelial Nitric Oxide Synthase Deficiency Exacerbates Cognitive Deficit and Amyloid Pathology in the APPswe/PS1ΔE9 Mouse Model of Alzheimer's Disease.
    Ahmed S, Jing Y, Mockett BG, Zhang H, Abraham WC, Liu P., Free PMC Article

    07/23/2022
    Downregulation of eNOS and preserved endothelial function in endothelial-specific arginase 1-deficient mice.

    Downregulation of eNOS and preserved endothelial function in endothelial-specific arginase 1-deficient mice.
    Heuser SK, LoBue A, Li J, Zhuge Z, Leo F, Suvorava T, Olsson A, Schneckmann R, Guimaraes Braga DD, Srivrastava T, Montero L, Schmitz OJ, Schmitt JP, Grandoch M, Weitzberg E, Lundberg JO, Pernow J, Kelm M, Carlström M, Cortese-Krott MM.

    07/23/2022
    Red blood cell eNOS is cardioprotective in acute myocardial infarction.

    Red blood cell eNOS is cardioprotective in acute myocardial infarction.
    Cortese-Krott MM, Suvorava T, Leo F, Heuser SK, LoBue A, Li J, Becher S, Schneckmann R, Srivrastava T, Erkens R, Wolff G, Schmitt JP, Grandoch M, Lundberg JO, Pernow J, Isakson BE, Weitzberg E, Kelm M., Free PMC Article

    07/16/2022
    Hepatocyte-specific eNOS deletion impairs exercise-induced adaptations in hepatic mitochondrial function and autophagy.

    Hepatocyte-specific eNOS deletion impairs exercise-induced adaptations in hepatic mitochondrial function and autophagy.
    Cunningham RP, Moore MP, Dashek RJ, Meers GM, Jepkemoi V, Takahashi T, Vieira-Potter VJ, Kanaley JA, Booth FW, Rector RS., Free PMC Article

    05/7/2022
    Endothelial TRPV4-eNOS coupling as a vital therapy target for treatment of hypertension.

    Endothelial TRPV4-eNOS coupling as a vital therapy target for treatment of hypertension.
    Mao A, Zhang P, Zhang K, Kan H, He D, Han X, Wang Z, Tang C, Ma X.

    04/16/2022
    Phosphorylation of Akt at Thr308 regulates p-eNOS Ser1177 during physiological conditions.

    Phosphorylation of Akt at Thr308 regulates p-eNOS Ser1177 during physiological conditions.
    Liang XX, Wang RY, Guo YZ, Cheng Z, Lv DY, Luo MH, He A, Luo SX, Xia Y., Free PMC Article

    04/9/2022
    Murine Beta-Amyloid (1-42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors.

    Murine Beta-Amyloid (1-42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors.
    Yue Q, Zhou X, Zhang Z, Hoi MPM., Free PMC Article

    03/12/2022
    Ventilatory responses during and following hypercapnic gas challenge are impaired in male but not female endothelial NOS knock-out mice.

    Ventilatory responses during and following hypercapnic gas challenge are impaired in male but not female endothelial NOS knock-out mice.
    Getsy PM, Sundararajan S, May WJ, von Schill GC, McLaughlin DK, Palmer LA, Lewis SJ., Free PMC Article

    02/5/2022
    The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function.

    The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function.
    Alghanem AF, Abello J, Maurer JM, Kumar A, Ta CM, Gunasekar SK, Fatima U, Kang C, Xie L, Adeola O, Riker M, Elliot-Hudson M, Minerath RA, Grueter CE, Mullins RF, Stratman AN, Sah R., Free PMC Article

    01/29/2022
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