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    Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 [ Mus musculus (house mouse) ]

    Gene ID: 18018, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Extracellular C1qbp inhibits myogenesis by suppressing NFATc1.

    Extracellular C1qbp inhibits myogenesis by suppressing NFATc1.
    Kim JM, Kim HK, Cho HJ, Moon SA, Kim Y, Hong JY, Lee SH, Kim K, Koh JM., Free PMC Article

    08/2/2024
    NFATc1 Is Required for Vitamin D- and Phosphate-Mediated Regulation of Osteocyte Lacuno-Canalicular Remodeling.

    NFATc1 Is Required for Vitamin D- and Phosphate-Mediated Regulation of Osteocyte Lacuno-Canalicular Remodeling.
    Jagga S, Hughes A, Manoochehri Arash N, Sorsby M, Brooks DJ, Divieti Pajevic P, Liu ES.,

    07/26/2024
    The G9a histone methyltransferase represses osteoclastogenesis and bone resorption by regulating NFATc1 function.

    The G9a histone methyltransferase represses osteoclastogenesis and bone resorption by regulating NFATc1 function.
    Komatsu K, Ideno H, Nakashima K, Udagawa N, Kobayashi Y, Kimura H, Tachibana M, Yamashita T, Nifuji A.

    07/13/2024
    The serine synthesis pathway drives osteoclast differentiation through epigenetic regulation of NFATc1 expression.

    The serine synthesis pathway drives osteoclast differentiation through epigenetic regulation of NFATc1 expression.
    Stegen S, Moermans K, Stockmans I, Thienpont B, Carmeliet G., Free PMC Article

    02/5/2024
    Dancr-BRG1 regulates Nfatc1 transcription and Pgc1beta-dependent metabolic shifts in osteoclastogenesis.

    Dancr-BRG1 regulates Nfatc1 transcription and Pgc1β-dependent metabolic shifts in osteoclastogenesis.
    Zhang Z, Meng Y, Lin T, Zhang Z, Tao Z, Yin H, Yang F, Zhou X., Free PMC Article

    02/1/2024
    Essentiality of Nfatc1 short isoform in osteoclast differentiation and its self-regulation.

    Essentiality of Nfatc1 short isoform in osteoclast differentiation and its self-regulation.
    Omata Y, Tachibana H, Aizaki Y, Mimura T, Sato K., Free PMC Article

    11/7/2023
    Systemic Inflammation and Normocytic Anemia in DOCK11 Deficiency.

    Systemic Inflammation and Normocytic Anemia in DOCK11 Deficiency.
    Block J, Rashkova C, Castanon I, Zoghi S, Platon J, Ardy RC, Fujiwara M, Chaves B, Schoppmeyer R, van der Made CI, Jimenez Heredia R, Harms FL, Alavi S, Alsina L, Sanchez Moreno P, Ávila Polo R, Cabrera-Pérez R, Kostel Bal S, Pfajfer L, Ransmayr B, Mautner AK, Kondo R, Tinnacher A, Caldera M, Schuster M, Domínguez Conde C, Platzer R, Salzer E, Boyer T, Brunner HG, Nooitgedagt-Frons JE, Iglesias E, Deyà-Martinez A, Camacho-Lovillo M, Menche J, Bock C, Huppa JB, Pickl WF, Distel M, Yoder JA, Traver D, Engelhardt KR, Linden T, Kager L, Hannich JT, Hoischen A, Hambleton S, Illsinger S, Da Costa L, Kutsche K, Chavoshzadeh Z, van Buul JD, Antón J, Calzada-Hernández J, Neth O, Viaud J, Nishikimi A, Dupré L, Boztug K.

    08/27/2023
    Interruption of TRPC6-NFATC1 signaling inhibits NADPH oxidase 4 and VSMCs phenotypic switch in intracranial aneurysm.

    Interruption of TRPC6-NFATC1 signaling inhibits NADPH oxidase 4 and VSMCs phenotypic switch in intracranial aneurysm.
    Sun ZH, Liu F, Kong LL, Ji PM, Huang L, Zhou HM, Sun R, Luo J, Li WZ.

    08/10/2023
    SIRT3-and FAK-mediated acetylation-phosphorylation crosstalk of NFATc1 regulates N[epsilon]-carboxymethyl-lysine-induced vascular calcification in diabetes mellitus.

    SIRT3-and FAK-mediated acetylation-phosphorylation crosstalk of NFATc1 regulates N(ε)-carboxymethyl-lysine-induced vascular calcification in diabetes mellitus.
    Sun Z, Zhang L, Yin K, Zang G, Qian Y, Mao X, Li L, Jing Q, Wang Z.

    07/25/2023
    Microglial LRRK2-mediated NFATc1 attenuates alpha-synuclein immunotoxicity in association with CX3CR1-induced migration and the lysosome-initiated degradation.

    Microglial LRRK2-mediated NFATc1 attenuates α-synuclein immunotoxicity in association with CX3CR1-induced migration and the lysosome-initiated degradation.
    Feng L, Lo H, Hong Z, Zheng J, Yan Y, Ye Z, Chen X, Pan X.

    07/10/2023
    Silencing of circCacna1c Inhibits ISO-Induced Cardiac Hypertrophy through miR-29b-2-5p/NFATc1 Axis.

    Silencing of circCacna1c Inhibits ISO-Induced Cardiac Hypertrophy through miR-29b-2-5p/NFATc1 Axis.
    Lu P, Zhang D, Ding F, Ma J, Xiang YK, Zhao M., Free PMC Article

    07/5/2023
    NFATc1-mediated expression of SLC7A11 drives sensitivity to TXNRD1 inhibitors in osteoclast precursors.

    NFATc1-mediated expression of SLC7A11 drives sensitivity to TXNRD1 inhibitors in osteoclast precursors.
    Zhong Z, Zhang C, Ni S, Ma M, Zhang X, Sang W, Lv T, Qian Z, Yi C, Yu B., Free PMC Article

    06/13/2023
    NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming.

    NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming.
    Zhang Z, Wang X, Hamdan FH, Likhobabina A, Patil S, Aperdannier L, Sen M, Traub J, Neesse A, Fischer A, Papantonis A, Singh SK, Ellenrieder V, Johnsen SA, Hessmann E., Free PMC Article

    04/24/2023
    NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation.

    NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation.
    Zhang F, Wang Y, Zhao Y, Wang M, Zhou B, Zhou B, Ge X., Free PMC Article

    04/7/2023
    CaMKII may regulate renal tubular epithelial cell apoptosis through YAP/NFAT2 in acute kidney injury mice.

    CaMKII may regulate renal tubular epithelial cell apoptosis through YAP/NFAT2 in acute kidney injury mice.
    Huang Z, Peng Y, Ke G, Xiao Y, Chen Y., Free PMC Article

    02/11/2023
    NFATc1 signaling drives chronic ER stress responses to promote NAFLD progression.

    NFATc1 signaling drives chronic ER stress responses to promote NAFLD progression.
    Latif MU, Schmidt GE, Mercan S, Rahman R, Gibhardt CS, Stejerean-Todoran I, Reutlinger K, Hessmann E, Singh SK, Moeed A, Rehman A, Butt UJ, Bohnenberger H, Stroebel P, Bremer SC, Neesse A, Bogeski I, Ellenrieder V., Free PMC Article

    11/12/2022
    Babam2 negatively regulates osteoclastogenesis by interacting with Hey1 to inhibit Nfatc1 transcription.

    Babam2 negatively regulates osteoclastogenesis by interacting with Hey1 to inhibit Nfatc1 transcription.
    Jin F, Zhu Y, Liu M, Wang R, Cui Y, Wu Y, Liu G, Wang Y, Wang X, Ren Z., Free PMC Article

    07/30/2022
    Serum/glucocorticoid-regulated kinase 1-targeted transient receptor potential oxalate subtype 1 regulates bladder smooth muscle cell proliferation due to bladder outlet obstruction in mice via activated T cell nuclear factor transcription factor 2.

    Serum/glucocorticoid-regulated kinase 1-targeted transient receptor potential oxalate subtype 1 regulates bladder smooth muscle cell proliferation due to bladder outlet obstruction in mice via activated T cell nuclear factor transcription factor 2.
    He J, Yang J, Chen L, He P, Liu X, Wang K, Dong T, Li J, Ma X, Bastian A, Arnulf S., Free PMC Article

    04/30/2022
    NFATc1/alphaA and Blimp-1 Support the Follicular and Effector Phenotype of Tregs.

    NFATc1/αA and Blimp-1 Support the Follicular and Effector Phenotype of Tregs.
    Koenig A, Vaeth M, Xiao Y, Chiarolla CM, Erapaneedi R, Klein M, Dietz L, Hundhausen N, Majumder S, Schuessler F, Bopp T, Klein-Hessling S, Rosenwald A, Berberich I, Berberich-Siebelt F., Free PMC Article

    03/5/2022
    Chromatin-Independent Interplay of NFATc1 and EZH2 in Pancreatic Cancer.

    Chromatin-Independent Interplay of NFATc1 and EZH2 in Pancreatic Cancer.
    Patil S, Forster T, Reutlinger K, Kopp W, Versemann L, Spitalieri J, Gaedcke J, Ströbel P, Singh SK, Ellenrieder V, Neesse A, Hessmann E., Free PMC Article

    01/22/2022
    NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy.

    NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy.
    Lewis EL, Xu R, Beltra JC, Ngiow SF, Cohen J, Telange R, Crane A, Sawinski D, Wherry EJ, Porrett PM., Free PMC Article

    01/8/2022
    Cooperative Binding of ETS2 and NFAT Links Erk1/2 and Calcineurin Signaling in the Pathogenesis of Cardiac Hypertrophy.

    Cooperative Binding of ETS2 and NFAT Links Erk1/2 and Calcineurin Signaling in the Pathogenesis of Cardiac Hypertrophy.
    Luo Y, Jiang N, May HI, Luo X, Ferdous A, Schiattarella GG, Chen G, Li Q, Li C, Rothermel BA, Jiang D, Lavandero S, Gillette TG, Hill JA., Free PMC Article

    01/1/2022
    RANK- NFATc1 signaling forms positive feedback loop on rank gene expression via functional NFATc1 responsive element in rank gene promoter.

    RANK- NFATc1 signaling forms positive feedback loop on rank gene expression via functional NFATc1 responsive element in rank gene promoter.
    Kitazawa R, Haraguchi R, Kohara Y, Kitazawa S.

    11/22/2021
    Rapid and Efficient Gene Editing for Direct Transplantation of Naive Murine Cas9(+) T Cells.

    Rapid and Efficient Gene Editing for Direct Transplantation of Naive Murine Cas9(+) T Cells.
    Majumder S, Jugovic I, Saul D, Bell L, Hundhausen N, Seal R, Beilhack A, Rosenwald A, Mougiakakos D, Berberich-Siebelt F., Free PMC Article

    10/30/2021
    Adenomatous Polyposis Coli Modulates Actin and Microtubule Cytoskeleton at the Immunological Synapse to Tune CTL Functions.

    Adenomatous Polyposis Coli Modulates Actin and Microtubule Cytoskeleton at the Immunological Synapse to Tune CTL Functions.
    Juzans M, Cuche C, Rose T, Mastrogiovanni M, Bochet P, Di Bartolo V, Alcover A.

    10/16/2021
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