| Dipeptidase 1 promotes ferroptosis in renal tubular epithelial cells in diabetic nephropathy via inhibition of the GSH/GPX4 axis. | Dipeptidase 1 promotes ferroptosis in renal tubular epithelial cells in diabetic nephropathy via inhibition of the GSH/GPX4 axis.
Li Y, Wang X, Zhang Q, Tian D, Bai Y, Feng Y, Liu W, Diao Z. | 06/17/2024 |
| DPEP1 promotes drug resistance in colon cancer cells by forming a positive feedback loop with ASCL2. | DPEP1 promotes drug resistance in colon cancer cells by forming a positive feedback loop with ASCL2.
Zeng C, Qi G, Shen Y, Li W, Zhu Q, Yang C, Deng J, Lu W, Liu Q, Jin J., Free PMC Article | 01/28/2023 |
| The relationship between common variants in the DPEP1 gene and the susceptibility and clinical severity of osteoarthritis. | The relationship between common variants in the DPEP1 gene and the susceptibility and clinical severity of osteoarthritis.
Zhang Z, Mei Y, Feng M, Wang C, Yang P, Tian R. | 01/22/2022 |
| A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis. | A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis.
Guan Y, Liang X, Ma Z, Hu H, Liu H, Miao Z, Linkermann A, Hellwege JN, Voight BF, Susztak K., Free PMC Article | 09/4/2021 |
| DPEP1 expression promotes proliferation and survival of leukaemia cells and correlates with relapse in adults with common B cell acute lymphoblastic leukaemia. | DPEP1 expression promotes proliferation and survival of leukaemia cells and correlates with relapse in adults with common B cell acute lymphoblastic leukaemia.
Zhang JM, Xu Y, Gale RP, Wu LX, Zhang J, Feng YH, Qin YZ, Jiang H, Jiang Q, Jiang B, Liu YR, Chen YH, Wang Y, Zhang XH, Xu LP, Huang XJ, Liu KY, Ruan GR. | 03/6/2021 |
| DPEP1 is a direct target of miR-193a-5p and promotes hepatoblastoma progression by PI3K/Akt/mTOR pathway. | DPEP1 is a direct target of miR-193a-5p and promotes hepatoblastoma progression by PI3K/Akt/mTOR pathway.
Cui X, Liu X, Han Q, Zhu J, Li J, Ren Z, Liu L, Luo Y, Wang Z, Zhang D, Fan Y, Zhang D, Dong G., Free PMC Article | 09/26/2020 |
| The results suggest that DPEP1 promotes cancer metastasis by regulating E-cadherin plasticity and that it might be a potential therapeutic target for preventing the progression of colon cancer. | Dehydropeptidase 1 promotes metastasis through regulation of E-cadherin expression in colon cancer.
Park SY, Lee SJ, Cho HJ, Kim TW, Kim JT, Kim JW, Lee CH, Kim BY, Yeom YI, Lim JS, Lee Y, Lee HG., Free PMC Article | 01/14/2017 |
| In this study, we present an analysis of Neanderthal introgression at the dipeptidase 1 gene, DPEP1. | Reintroduction of a Homocysteine Level-Associated Allele into East Asians by Neanderthal Introgression.
Hu Y, Ding Q, He Y, Xu S, Jin L. | 09/24/2016 |
| Dipeptidase 1 has been identified as an excellent marker of high-grade IEN and CRC, and may thus be applied for screening of early neoplastic lesions and for prognostic stratification. | Dipeptidase 1 (DPEP1) is a marker for the transition from low-grade to high-grade intraepithelial neoplasia and an adverse prognostic factor in colorectal cancer.
Eisenach PA, Soeth E, Röder C, Klöppel G, Tepel J, Kalthoff H, Sipos B., Free PMC Article | 11/30/2013 |
| DPEP1 plays a role in pancreatic cancer aggressiveness. | DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma.
Zhang G, Schetter A, He P, Funamizu N, Gaedcke J, Ghadimi BM, Ried T, Hassan R, Yfantis HG, Lee DH, Lacy C, Maitra A, Hanna N, Alexander HR, Hussain SP., Free PMC Article | 06/30/2012 |
| DPEP1 is expressed in the early stages of colon carcinogenesis and affects cancer cell invasiveness. | DPEP1, expressed in the early stages of colon carcinogenesis, affects cancer cell invasiveness.
Toiyama Y, Inoue Y, Yasuda H, Saigusa S, Yokoe T, Okugawa Y, Tanaka K, Miki C, Kusunoki M. | 07/16/2011 |
| we identified a novel immunohistochemical marker, dipeptidase 1, to distinguish primary mucinous ovarian cancers from ovarian metastasis of colorectal cancers. | Distinguishing primary from secondary mucinous ovarian tumors: an algorithm using the novel marker DPEP1.
Okamoto T, Matsumura N, Mandai M, Oura T, Yamanishi Y, Horiuchi A, Hamanishi J, Baba T, Koshiyama M, Shiozawa T, Konishi I. | 07/2/2011 |
| CPS1, MUT, NOX4, and DPEP1 is associated with plasma homocysteine in healthy Women. | Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.
Paré G, Chasman DI, Parker AN, Zee RR, Mälarstig A, Seedorf U, Collins R, Watkins H, Hamsten A, Miletich JP, Ridker PM, Paré G, Chasman DI, Parker AN, Zee RR, Mälarstig A, Seedorf U, Collins R, Watkins H, Hamsten A, Miletich JP, Ridker PM., Free PMC Articles: PMC2745176, PMC2745176 | 03/8/2010 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.
Paré G, Chasman DI, Parker AN, Zee RR, Mälarstig A, Seedorf U, Collins R, Watkins H, Hamsten A, Miletich JP, Ridker PM, Paré G, Chasman DI, Parker AN, Zee RR, Mälarstig A, Seedorf U, Collins R, Watkins H, Hamsten A, Miletich JP, Ridker PM., Free PMC Articles: PMC2745176, PMC2745176 | 01/20/2010 |
| DPEP1 has a role in colorectal carcinoma | Dipeptidase 1: a candidate tumor-specific molecular marker in colorectal carcinoma.
McIver CM, Lloyd JM, Hewett PJ, Hardingham JE. | 01/21/2010 |
| Crystal structure of human renal dipeptidase involved in beta-lactam hydrolysis | Crystal structure of human renal dipeptidase involved in beta-lactam hydrolysis.
Nitanai Y, Satow Y, Adachi H, Tsujimoto M. | 01/21/2010 |