| Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer. | Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer.
Boufaied N, Chetta P, Hallal T, Cacciatore S, Lalli D, Luthold C, Homsy K, Imada EL, Syamala S, Photopoulos C, Di Matteo A, de Polo A, Storaci AM, Huang Y, Giunchi F, Sheridan PA, Michelotti G, Nguyen QD, Zhao X, Liu Y, Davicioni E, Spratt DE, Sabbioneda S, Maga G, Mucci LA, Ghigna C, Marchionni L, Butler LM, Ellis L, Bordeleau F, Loda M, Vaira V, Labbé DP, Zadra G., Free PMC Article | 09/3/2024 |
| Runx3 is required for oncogenic Myc upregulation in p53-deficient osteosarcoma. | Runx3 is required for oncogenic Myc upregulation in p53-deficient osteosarcoma.
Otani S, Date Y, Ueno T, Ito T, Kajikawa S, Omori K, Taniuchi I, Umeda M, Komori T, Toguchida J, Ito K. | 08/28/2024 |
| MYC Promotes Aggressive Growth and Metastasis of a WNT-Medulloblastoma Mouse Model. | MYC Promotes Aggressive Growth and Metastasis of a WNT-Medulloblastoma Mouse Model.
Hartley R, Phoenix TN. | 06/12/2024 |
| ADORA2B, transcriptionally suppressing by MYC, promotes ferroptosis of chondrocytes via inhibition of the PI3K/Akt pathway in mice with osteoarthritis. | ADORA2B, transcriptionally suppressing by MYC, promotes ferroptosis of chondrocytes via inhibition of the PI3K/Akt pathway in mice with osteoarthritis.
Li S, Han J, Cao J, Han H, Lu B, Wen T, Bian W. | 05/6/2024 |
| PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma. | PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma.
Gaballa A, Gebhardt-Wolf A, Krenz B, Mattavelli G, John M, Cossa G, Andreani S, Schülein-Völk C, Montesinos F, Vidal R, Kastner C, Ade CP, Kneitz B, Gasteiger G, Gallant P, Rosenfeldt M, Riedel A, Eilers M., Free PMC Article | 03/1/2024 |
| Collaborative effect of Csnk1a1 haploinsufficiency and mutant p53 in Myc induction can promote leukemic transformation. | Collaborative effect of Csnk1a1 haploinsufficiency and mutant p53 in Myc induction can promote leukemic transformation.
Fuchs SNR, Stalmann USA, Snoeren IAM, Bindels E, Schmitz S, Banjanin B, Hoogenboezem RM, van Herk S, Saad M, Walter W, Haferlach T, Seillier L, Saez-Rodriguez J, Dugourd AJF, Lehmann KV, Ben-Neriah Y, Gleitz HFE, Schneider RK., Free PMC Article | 02/9/2024 |
| Arginine-methylated c-Myc affects mitochondrial mitophagy in mouse acute kidney injury via Slc25a24. | Arginine-methylated c-Myc affects mitochondrial mitophagy in mouse acute kidney injury via Slc25a24.
Liu Y, Liu N, He P, Cao S, Li H, Liu D. | 02/5/2024 |
| WWOX promotes osteosarcoma development via upregulation of Myc. | WWOX promotes osteosarcoma development via upregulation of Myc.
Akkawi R, Hidmi O, Haj-Yahia A, Monin J, Diment J, Drier Y, Stein GS, Aqeilan RI., Free PMC Article | 01/26/2024 |
| MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression. | MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression.
Chen J, Zheng Q, Hicks JL, Trabzonlu L, Ozbek B, Jones T, Vaghasia AM, Larman TC, Wang R, Markowski MC, Denmeade SR, Pienta KJ, Hruban RH, Antonarakis ES, Gupta A, Dang CV, Yegnasubramanian S, De Marzo AM., Free PMC Article | 01/3/2024 |
| Myc-dependent dedifferentiation of Gata6[+] epidermal cells resembles reversal of terminal differentiation. | Myc-dependent dedifferentiation of Gata6(+) epidermal cells resembles reversal of terminal differentiation.
Bernabé-Rubio M, Ali S, Bhosale PG, Goss G, Mobasseri SA, Tapia-Rojo R, Zhu T, Hiratsuka T, Battilocchi M, Tomás IM, Ganier C, Garcia-Manyes S, Watt FM., Free PMC Article | 12/23/2023 |
| MYC acetylated lysine residues drive oncogenic cell transformation and regulate select genetic programs for cell adhesion-independent growth and survival. | MYC acetylated lysine residues drive oncogenic cell transformation and regulate select genetic programs for cell adhesion-independent growth and survival.
Hurd M, Pino J, Jang K, Allevato MM, Vorontchikhina M, Ichikawa W, Zhao Y, Gates R, Villalpando E, Hamilton MJ, Faiola F, Pan S, Qi Y, Hung YW, Girke T, Ann D, Seewaldt V, Martinez E., Free PMC Article | 11/18/2023 |
| c-Myc inhibits LAPTM5 expression in B-cell lymphomas. | c-Myc inhibits LAPTM5 expression in B-cell lymphomas.
Zhang Y, Zhang X, Zhang Y, Xu H, Wei Z, Wang X, Li Y, Guo J, Wu F, Fang X, Pang L, Deng B, Yu D. | 11/14/2023 |
| MYC directly transactivates CR2/CD21, the receptor of the Epstein-Barr virus, enhancing the viral infection of Burkitt lymphoma cells. | MYC directly transactivates CR2/CD21, the receptor of the Epstein-Barr virus, enhancing the viral infection of Burkitt lymphoma cells.
Molina E, García-Gutiérrez L, Junco V, Perez-Olivares M, de Yébenes VG, Blanco R, Quevedo L, Acosta JC, Marín AV, Ulgiati D, Merino R, Delgado MD, Varela I, Regueiro JR, Moreno de Alborán I, Ramiro AR, León J. | 11/13/2023 |
| MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice. | MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice.
Göbel C, Godbole S, Schoof M, Holdhof D, Kresbach C, Loose C, Neumann J, Schüller U., Free PMC Article | 11/8/2023 |
| MYC-MAX heterodimerization is essential for the induction of major zygotic genome activation and subsequent preimplantation development. | MYC-MAX heterodimerization is essential for the induction of major zygotic genome activation and subsequent preimplantation development.
Yamamoto T, Wang H, Sato H, Honda S, Ikeda S, Minami N., Free PMC Article | 09/29/2023 |
| MYC Deregulation and PTEN Loss Model Tumor and Stromal Heterogeneity of Aggressive Triple-Negative Breast Cancer. | MYC Deregulation and PTEN Loss Model Tumor and Stromal Heterogeneity of Aggressive Triple-Negative Breast Cancer.
Doha ZO, Wang X, Calistri NL, Eng J, Daniel CJ, Ternes L, Kim EN, Pelz C, Munks M, Betts C, Kwon S, Bucher E, Li X, Waugh T, Tatarova Z, Blumberg D, Ko A, Kirchberger N, Pietenpol JA, Sanders ME, Langer EM, Dai MS, Mills G, Chin K, Chang YH, Coussens LM, Gray JW, Heiser LM, Sears RC., Free PMC Article | 09/19/2023 |
| RNF130 protects against pulmonary fibrosis through suppressing aerobic glycolysis by mediating c-myc ubiquitination. | RNF130 protects against pulmonary fibrosis through suppressing aerobic glycolysis by mediating c-myc ubiquitination.
Zhang J, Chen W, Du J, Chu L, Zhou Z, Zhong W, Liu D, Huang H, Huang Y, Qiao Y, Meng X, Zou F, Cai S, Dong H. | 08/11/2023 |
| MYC regulates CSF1 expression via microRNA 17/20a to modulate tumor-associated macrophages in osteosarcoma. | MYC regulates CSF1 expression via microRNA 17/20a to modulate tumor-associated macrophages in osteosarcoma.
Nirala BK, Patel TD, Kurenbekova L, Shuck R, Dasgupta A, Rainusso N, Coarfa C, Yustein JT., Free PMC Article | 07/12/2023 |
| Pathologic HDAC1/c-Myc signaling axis is responsible for angiotensinogen transcription and hypertension induced by high-fat diet. | Pathologic HDAC1/c-Myc signaling axis is responsible for angiotensinogen transcription and hypertension induced by high-fat diet.
Youn EK, Cho HM, Jung JK, Yoon GE, Eto M, Kim JI. | 06/26/2023 |
| Myc promotes polyploidy in murine trophoblast cells and suppresses senescence. | Myc promotes polyploidy in murine trophoblast cells and suppresses senescence.
Singh VP, Hassan H, Deng F, Tsuchiya D, McKinney S, Ferro K, Gerton JL., Free PMC Article | 06/8/2023 |
| Transcription factor YY1 mediates self-renewal of glioblastoma stem cells through regulation of the SENP1/METTL3/MYC axis. | Transcription factor YY1 mediates self-renewal of glioblastoma stem cells through regulation of the SENP1/METTL3/MYC axis.
You J, Tao B, Peng L, Peng T, He H, Zeng S, Han J, Chen L, Xia X, Yang X, Zhong C. | 05/19/2023 |
| Tespa1 facilitates hematopoietic and leukemic stem cell maintenance by restricting c-Myc degradation. | Tespa1 facilitates hematopoietic and leukemic stem cell maintenance by restricting c-Myc degradation.
Lu Y, Yang L, Shen M, Zhang Z, Wang S, Chen F, Chen N, Xu Y, Zeng H, Chen M, Chen S, Wang F, Hu M, Wang J., Free PMC Article | 05/13/2023 |
| Myc controls NK cell development, IL-15-driven expansion, and translational machinery. | Myc controls NK cell development, IL-15-driven expansion, and translational machinery.
Khameneh HJ, Fonta N, Zenobi A, Niogret C, Ventura P, Guerra C, Kwee I, Rinaldi A, Pecoraro M, Geiger R, Cavalli A, Bertoni F, Vivier E, Trumpp A, Guarda G., Free PMC Article | 05/8/2023 |
| Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation. | Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation.
Coni S, Bordone R, Ivy DM, Yurtsever ZN, Di Magno L, D'Amico R, Cesaro B, Fatica A, Belardinilli F, Bufalieri F, Maroder M, De Smaele E, Di Marcotullio L, Giannini G, Agostinelli E, Canettieri G. | 04/4/2023 |
| High levels of Myc expression are required for the robust proliferation of hepatocytes, but not for the sustained weak proliferation. | High levels of Myc expression are required for the robust proliferation of hepatocytes, but not for the sustained weak proliferation.
Goto M, Ooshio T, Yamamoto M, Tanaka H, Fujii Y, Meng L, Kamikokura Y, Okada Y, Nishikawa Y. | 03/28/2023 |