| Obesity promotes the global hypomethylation of CD4+ T cells in patients with systemic lupus erythematosus via downregulating DNMT1. | Obesity promotes the global hypomethylation of CD4+ T cells in patients with systemic lupus erythematosus via downregulating DNMT1.
Hou L, Li S, Zhao M. | 10/28/2024 |
| DNMT1-Mediated the Downregulation of FOXF1 Promotes High Glucose-induced Podocyte Damage by Regulating the miR-342-3p/E2F1 Axis. | DNMT1-Mediated the Downregulation of FOXF1 Promotes High Glucose-induced Podocyte Damage by Regulating the miR-342-3p/E2F1 Axis.
Chen JH, Ye L, Zhu SL, Yang Y, Xu N. | 10/8/2024 |
| LncRNA FAM83H-AS1 inhibits ferroptosis of endometrial cancer by promoting DNMT1-mediated CDO1 promoter hypermethylation. | LncRNA FAM83H-AS1 inhibits ferroptosis of endometrial cancer by promoting DNMT1-mediated CDO1 promoter hypermethylation.
Wang R, Yu X, Ye H, Ao M, Xi M, Hou M., Free PMC Article | 10/8/2024 |
| Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma. | Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma.
Tsiami F, Lago C, Pozza N, Piccioni F, Zhao X, Lülsberg F, Root DE, Tiberi L, Kool M, Schittenhelm J, Bandopadhayay P, Segal RA, Tabatabai G, Merk DJ., Free PMC Article | 09/13/2024 |
| DNMT1 regulates human erythropoiesis by modulating cell cycle and endoplasmic reticulum stress in a stage-specific manner. | DNMT1 regulates human erythropoiesis by modulating cell cycle and endoplasmic reticulum stress in a stage-specific manner.
Yang Q, Chen L, Zhang H, Li M, Sun L, Wu X, Zhao H, Qu X, An X, Wang T., Free PMC Article | 09/13/2024 |
| Structural insight into the DNMT1 reaction cycle by cryo-electron microscopy. | Structural insight into the DNMT1 reaction cycle by cryo-electron microscopy.
De I, Weidenhausen J, Concha N, Müller CW., Free PMC Article | 09/13/2024 |
| DNMT1-targeting remodeling global DNA hypomethylation for enhanced tumor suppression and circumvented toxicity in oral squamous cell carcinoma. | DNMT1-targeting remodeling global DNA hypomethylation for enhanced tumor suppression and circumvented toxicity in oral squamous cell carcinoma.
Liu Y, Sun Y, Yang J, Wu D, Yu S, Liu J, Hu T, Luo J, Zhou H., Free PMC Article | 08/15/2024 |
| Role of LINC00240 on T-helper 9 differentiation in allergic rhinitis through influencing DNMT1-dependent methylation of PU.1. | Role of LINC00240 on T-helper 9 differentiation in allergic rhinitis through influencing DNMT1-dependent methylation of PU.1.
Liu J, Jiang X, Liu K, Deng J, Qiu Y, Wei W, Yang C. | 04/26/2024 |
| An updated meta-analysis investigating the association between DNMTs gene polymorphism andgastric cancer risk. | An updated meta-analysis investigating the association between DNMTs gene polymorphism andgastric cancer risk.
Zhang YL, Wang YW, He MJ, Chang JL., Free PMC Article | 04/24/2024 |
| Unveiling the impact of DNA methylation machinery: Dnmt1 and Dnmt3a in orchestrating oocyte development and cellular homeostasis. | Unveiling the impact of DNA methylation machinery: Dnmt1 and Dnmt3a in orchestrating oocyte development and cellular homeostasis.
Uysal F, Sukur G, Bozdemir N, Cinar O. | 04/23/2024 |
| DNMT1/miR-152-3p/SOS1 signaling axis promotes self-renewal and tumor growth of cancer stem-like cells derived from non-small cell lung cancer. | DNMT1/miR-152-3p/SOS1 signaling axis promotes self-renewal and tumor growth of cancer stem-like cells derived from non-small cell lung cancer.
Yuan Q, Wang R, Li X, Sun F, Lin J, Fu Z, Zhang J., Free PMC Article | 04/22/2024 |
| Identification of a conserved alpha-helical domain at the N terminus of human DNA methyltransferase 1. | Identification of a conserved α-helical domain at the N terminus of human DNA methyltransferase 1.
Hu Q, Botuyan MV, Mer G., Free PMC Article | 04/4/2024 |
| Mutations in human DNA methyltransferase DNMT1 induce specific genome-wide epigenomic and transcriptomic changes in neurodevelopment. | Mutations in human DNA methyltransferase DNMT1 induce specific genome-wide epigenomic and transcriptomic changes in neurodevelopment.
Davis KN, Qu PP, Ma S, Lin L, Plastini M, Dahl N, Plazzi G, Pizza F, O'Hara R, Wong WH, Hallmayer J, Mignot E, Zhang X, Urban AE., Free PMC Article | 03/21/2024 |
| Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization. | Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization.
Scelfo A, Barra V, Abdennur N, Spracklin G, Busato F, Salinas-Luypaert C, Bonaiti E, Velasco G, Bonhomme F, Chipont A, Tijhuis AE, Spierings DCJ, Guérin C, Arimondo P, Francastel C, Foijer F, Tost J, Mirny L, Fachinetti D., Free PMC Article | 02/28/2024 |
| DNMT1-mediated regulating on FBXO32 promotes the progression of glioma cells through the regulation of SKP1 activity. | DNMT1-mediated regulating on FBXO32 promotes the progression of glioma cells through the regulation of SKP1 activity.
Quan J, Ma C. | 01/11/2024 |
| The Role of DNMT1 and C/EBPalpha in the Regulation of CYP11A1 Expression During Syncytialization of Human Placental Trophoblasts. | The Role of DNMT1 and C/EBPα in the Regulation of CYP11A1 Expression During Syncytialization of Human Placental Trophoblasts.
Zhu YN, Pan F, Gan XW, Liu Y, Wang WS, Sun K. | 01/4/2024 |
| MIR143HG promotes methylation of transcription factor HOXB7 promoter by recruiting methyltransferase DNMT1 to prevent the progression of colon cancer. | MIR143HG promotes methylation of transcription factor HOXB7 promoter by recruiting methyltransferase DNMT1 to prevent the progression of colon cancer.
Zhu M, Xu T, Ji L, Jiang B, Wu K. | 12/27/2023 |
| Insights into DNMT1 and programmed cell death in diseases. | Insights into DNMT1 and programmed cell death in diseases.
Yan L, Geng Q, Cao Z, Liu B, Li L, Lu P, Lin L, Wei L, Tan Y, He X, Li L, Zhao N, Lu C. | 11/30/2023 |
| Estrogen inhibits the differentiation of fibroblasts induced by high stiffness matrix by enhancing DNMT1 expression. | Estrogen inhibits the differentiation of fibroblasts induced by high stiffness matrix by enhancing DNMT1 expression.
Zhao Z, Huang G, He Y, Zuo X, Han W, Li H. | 11/16/2023 |
| DNMT1-mediated NR3C1 DNA methylation enables transcription activation of connexin40 and augments angiogenesis during colorectal cancer progression. | DNMT1-mediated NR3C1 DNA methylation enables transcription activation of connexin40 and augments angiogenesis during colorectal cancer progression.
Zhai P, Zhang H, Li Q, Yang M, Guo Y, Xing C. | 11/7/2023 |
| Evaluation of epigenetic-related gene expression (DNMT, HDAC1) in Iranian patients with systemic lupus erythematosus. | Evaluation of epigenetic-related gene expression (DNMT, HDAC1) in Iranian patients with systemic lupus erythematosus.
Abbasifard M, Mohammadiranjbar F, Mohammad-Sadeghipour M, Mahmoodi M, Hassanshahi G, Swann J, Zarei S, Hosseiniara R, Hajizadeh MR. | 11/6/2023 |
| Correlation between peripheral blood alpha1-MG, DNMT1 expression, and the severity of diabetic nephropathy renal pathological damage. | Correlation between peripheral blood α1-MG, DNMT1 expression, and the severity of diabetic nephropathy renal pathological damage.
Jin L, Niu C, Ni Y., Free PMC Article | 10/30/2023 |
| DNMT1 regulates miR-20a/TXNIP-mediated pyroptosis of retinal pigment epithelial cells through DNA methylation. | DNMT1 regulates miR-20a/TXNIP-mediated pyroptosis of retinal pigment epithelial cells through DNA methylation.
Xi X, Wang M, Chen Q, Ma J, Zhang J, Li Y. | 10/11/2023 |
| DNMT1 expression partially dictates 5-Azacytidine sensitivity and correlates with RAS/MEK/ERK activity in gastric cancer cells. | DNMT1 expression partially dictates 5-Azacytidine sensitivity and correlates with RAS/MEK/ERK activity in gastric cancer cells.
Chen Z, Zhang L, Yang Y, Liu H, Kang X, Nie Y, Fan D., Free PMC Article | 09/28/2023 |
| DNMT1-mediated DNA methylation in toll-like receptor 4 (TLR4) inactivates NF-kappaB signal pathway-triggered pyroptotic cell death and cellular inflammation to ameliorate lipopolysaccharides (LPS)-induced osteomyelitis. | DNMT1-mediated DNA methylation in toll-like receptor 4 (TLR4) inactivates NF-κB signal pathway-triggered pyroptotic cell death and cellular inflammation to ameliorate lipopolysaccharides (LPS)-induced osteomyelitis.
Song M, Li J, Sun J, Yang X, Zhang X, Lv K, Xu Y, Shi J. | 09/20/2023 |