| [The dynamin-2-gene related centronuclear myopathy]. | [The dynamin-2-gene related centronuclear myopathy].
Bitoun M. | 11/28/2023 |
| BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes. | BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes.
Perdreau-Dahl H, Lipsett DB, Frisk M, Kermani F, Carlson CR, Brech A, Shen X, Bergan-Dahl A, Hou Y, Tuomainen T, Tavi P, Jones PP, Lunde M, Wasserstrom JA, Laporte J, Ullrich ND, Christensen G, Morth JP, Louch WE. | 06/2/2023 |
| Implication of Dynamin-2 (DNM2) Mutations in Adult T-cell Acute Lymphoblastic Leukemia. | Implication of Dynamin-2 (DNM2) Mutations in Adult T-cell Acute Lymphoblastic Leukemia.
Sobh M, Aref S, Al Agdar M, El Zafrany M, El-Sokkary AMA., Free PMC Article | 05/3/2023 |
| Dynamin-2 regulates microtubule stability via an endocytosis-independent mechanism. | Dynamin-2 regulates microtubule stability via an endocytosis-independent mechanism.
Guo R, Fujito R, Nagasaki A, Okumura M, Chihara T, Hamao K. | 12/24/2022 |
| Gain-of-Function Dynamin-2 Mutations Linked to Centronuclear Myopathy Impair Ca(2+)-Induced Exocytosis in Human Myoblasts. | Gain-of-Function Dynamin-2 Mutations Linked to Centronuclear Myopathy Impair Ca(2+)-Induced Exocytosis in Human Myoblasts.
Bayonés L, Guerra-Fernández MJ, Hinostroza F, Báez-Matus X, Vásquez-Navarrete J, Gallo LI, Parra S, Martínez AD, González-Jamett A, Marengo FD, Cárdenas AM., Free PMC Article | 10/8/2022 |
| Serum exosomal coronin 1A and dynamin 2 as neural tube defect biomarkers. | Serum exosomal coronin 1A and dynamin 2 as neural tube defect biomarkers.
Wang Y, Ma L, Jia S, Liu D, Gu H, Wei X, Ma W, Luo W, Bai Y, Wang W, Yuan Z., Free PMC Article | 09/3/2022 |
| Imaging-based evaluation of pathogenicity by novel DNM2 variants associated with centronuclear myopathy. | Imaging-based evaluation of pathogenicity by novel DNM2 variants associated with centronuclear myopathy.
Fujise K, Okubo M, Abe T, Yamada H, Takei K, Nishino I, Takeda T, Noguchi S. | 05/7/2022 |
| BIN1 modulation in vivo rescues dynamin-related myopathy. | BIN1 modulation in vivo rescues dynamin-related myopathy.
Lionello VM, Kretz C, Edelweiss E, Crucifix C, Gómez-Oca R, Messaddeq N, Buono S, Koebel P, Massana Muñoz X, Diedhiou N, Cowling BS, Bitoun M, Laporte J., Free PMC Article | 03/19/2022 |
| Beta-Pix-dynamin 2 complex promotes colorectal cancer progression by facilitating membrane dynamics. | Beta-Pix-dynamin 2 complex promotes colorectal cancer progression by facilitating membrane dynamics.
Keum S, Yang SJ, Park E, Kang T, Choi JH, Jeong J, Hwang YE, Kim JW, Park D, Rhee S., Free PMC Article | 03/12/2022 |
| Dynamin-2 mediates clathrin-dependent endocytosis for amyloid-beta internalization in brain microvascular endothelial cells. | Dynamin-2 mediates clathrin-dependent endocytosis for amyloid-β internalization in brain microvascular endothelial cells.
Du SS, Sun X, Cen J, Shi JX, An MX, Zhao WD. | 03/5/2022 |
| Dynamin regulates L cell secretion in human gut. | Dynamin regulates L cell secretion in human gut.
Sun EW, Matusica D, Wattchow DA, McCluskey A, Robinson PJ, Keating DJ. | 01/29/2022 |
| Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance. | Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance.
Lodillinsky C, Fuhrmann L, Irondelle M, Pylypenko O, Li XY, Bonsang-Kitzis H, Reyal F, Vacher S, Calmel C, De Wever O, Bièche I, Lacombe ML, Eiján AM, Houdusse A, Vincent-Salomon A, Weiss SJ, Chavrier P, Boissan M., Free PMC Article | 01/15/2022 |
| Dynamin 2 and BAR domain protein pacsin 2 cooperatively regulate formation and maturation of podosomes. | Dynamin 2 and BAR domain protein pacsin 2 cooperatively regulate formation and maturation of podosomes.
Li J, Fujise K, Wint H, Senju Y, Suetsugu S, Yamada H, Takei K, Takeda T. | 11/22/2021 |
| Mice carrying an analogous heterozygous dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathy. | Mice carrying an analogous heterozygous dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathy.
Pereira JA, Gerber J, Ghidinelli M, Gerber D, Tortola L, Ommer A, Bachofner S, Santarella F, Tinelli E, Lin S, Rüegg MA, Kopf M, Toyka KV, Suter U., Free PMC Article | 08/7/2021 |
| A new mutation in DNM2 gene in a large Italian family. | A new mutation in DNM2 gene in a large Italian family.
Lopergolo D, Bocci S, Pinto AM, Valentino F, Doddato G, Ginanneschi F, Volpi N, Renieri A, Giannini F. | 06/5/2021 |
| Dynamin 2 Is Correlated with Recurrence and Poor Prognosis of Papillary Thyroid Cancer. | Dynamin 2 Is Correlated with Recurrence and Poor Prognosis of Papillary Thyroid Cancer.
Ren N, Tian Z, Sun H, Lu X., Free PMC Article | 05/22/2021 |
| The Expression of Dynamin 1, 2, and 3 in Human Hepatocellular Carcinoma and Patient Prognosis. | The Expression of Dynamin 1, 2, and 3 in Human Hepatocellular Carcinoma and Patient Prognosis.
Tian M, Yang X, Li Y, Guo S., Free PMC Article | 04/24/2021 |
| Dynamin-2 R465W mutation induces long range perturbation in highly ordered oligomeric structures. | Dynamin-2 R465W mutation induces long range perturbation in highly ordered oligomeric structures.
Hinostroza F, Neely A, Araya-Duran I, Marabolí V, Canan J, Rojas M, Aguayo D, Latorre R, González-Nilo FD, Cárdenas AM., Free PMC Article | 01/23/2021 |
| Dynamin 2 interacts with alpha-actinin 4 to drive tumor cell invasion. | Dynamin 2 interacts with α-actinin 4 to drive tumor cell invasion.
Burton KM, Cao H, Chen J, Qiang L, Krueger EW, Johnson KM, Bamlet WR, Zhang L, McNiven MA, Razidlo GL., Free PMC Article | 01/23/2021 |
| A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy. | A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy.
Puri C, Manni MM, Vicinanza M, Hilcenko C, Zhu Y, Runwal G, Stamatakou E, Menzies FM, Mamchaoui K, Bitoun M, Rubinsztein DC. | 12/19/2020 |
| Mechanistic study of PpIX accumulation using the JFCR39 cell panel revealed a role for dynamin 2-mediated exocytosis. | Mechanistic study of PpIX accumulation using the JFCR39 cell panel revealed a role for dynamin 2-mediated exocytosis.
Kitajima Y, Ishii T, Kohda T, Ishizuka M, Yamazaki K, Nishimura Y, Tanaka T, Dan S, Nakajima M., Free PMC Article | 10/24/2020 |
| Expression of WT and CNM mutants recreate a CNM-like phenotype, suggesting CNM mutations are gain-of-function. Histological, ultrastructural and molecular analyses pointed to key pathways uncovering the different pathomechanisms involved in centronuclear myopathy or Charcot-Marie-Tooth neuropathy linked to DNM2 mutations. | Different in vivo impacts of dynamin 2 mutations implicated in Charcot-Marie-Tooth neuropathy or centronuclear myopathy.
Massana Muñoz X, Buono S, Koebel P, Laporte J, Cowling BS. | 06/27/2020 |
| Using the power of the zebrafish, authors establish novel insights into dynamin 2 localization and dynamics and provide the necessary groundwork for future studies examining dynamin 2 pathomechanisms. | Insights into wild-type dynamin 2 and the consequences of DNM2 mutations from transgenic zebrafish.
Zhao M, Smith L, Volpatti J, Fabian L, Dowling JJ. | 06/27/2020 |
| High NME1 and NME2 Promote Dynamin 2 Oligomerization and Regulate Tumor Cell Endocytosis, Motility, and breast cancer Metastasis. | Metastasis Suppressors NME1 and NME2 Promote Dynamin 2 Oligomerization and Regulate Tumor Cell Endocytosis, Motility, and Metastasis.
Khan I, Gril B, Steeg PS., Free PMC Article | 05/30/2020 |
| CNM mutations in DNM2 affect the distribution of caveoli. | Correlative SICM-FCM reveals changes in morphology and kinetics of endocytic pits induced by disease-associated mutations in dynamin.
Ali T, Bednarska J, Vassilopoulos S, Tran M, Diakonov IA, Ziyadeh-Isleem A, Guicheney P, Gorelik J, Korchev YE, Reilly MM, Bitoun M, Shevchuk A., Free PMC Article | 05/23/2020 |