| The Expression of MMP1 and MMP7 in Mice Liver after Exposure to Aflatoxin B1 Using Immunohistochemistry Technique. | The Expression of MMP1 and MMP7 in Mice Liver after Exposure to Aflatoxin B1 Using Immunohistochemistry Technique.
Al-Mudallal NHAL., Free PMC Article | 06/21/2023 |
| Matrix Metalloproteinase 7 Expression and Apical Epithelial Defects in Atp8b1 Mutant Mouse Model of Pulmonary Fibrosis. | Matrix Metalloproteinase 7 Expression and Apical Epithelial Defects in Atp8b1 Mutant Mouse Model of Pulmonary Fibrosis.
Westermann-Clark E, Soundararajan R, Fukumoto J, Patil SS, Stearns TM, Saji S, Czachor A, Hernandez-Cuervo H, Breitzig M, Krishnamurthy S, Lockey RF, Kolliputi N., Free PMC Article | 04/16/2022 |
| Matrix metalloproteinase-7 in platelet-activated macrophages accounts for cardiac remodeling in uremic mice. | Matrix metalloproteinase-7 in platelet-activated macrophages accounts for cardiac remodeling in uremic mice.
Yang Y, Ma L, Wang C, Song M, Li C, Chen M, Zhou J, Mei C. | 06/26/2021 |
| Matrix Metalloproteinases Retain Soluble FasL-mediated Resistance to Cell Death in Fibrotic-Lung Myofibroblasts. | Matrix Metalloproteinases Retain Soluble FasL-mediated Resistance to Cell Death in Fibrotic-Lung Myofibroblasts.
Nareznoi D, Konikov-Rozenman J, Petukhov D, Breuer R, Wallach-Dayan SB., Free PMC Article | 02/27/2021 |
| Tubular injury triggers podocyte dysfunction by beta-catenin-driven release of MMP-7. | Tubular injury triggers podocyte dysfunction by β-catenin-driven release of MMP-7.
Tan RJ, Li Y, Rush BM, Cerqueira DM, Zhou D, Fu H, Ho J, Beer Stolz D, Liu Y., Free PMC Article | 10/24/2020 |
| Study results suggest that induction of MMP-7 is protective in acute kidney injury by degrading FasL and mobilizing beta-catenin, thereby priming kidney tubules for survival and regeneration. | Matrix metalloproteinase-7 protects against acute kidney injury by priming renal tubules for survival and regeneration.
Fu H, Zhou D, Zhu H, Liao J, Lin L, Hong X, Hou FF, Liu Y., Free PMC Article | 04/4/2020 |
| FXR suppresses MMP7 transcription by binding to a negative FXR-responsive element in the 5' MMP7 promoter, an event that inhibited colon cancer cell proliferation and invasion. | Farnesoid X receptor represses matrix metalloproteinase 7 expression, revealing this regulatory axis as a promising therapeutic target in colon cancer.
Peng Z, Chen J, Drachenberg CB, Raufman JP, Xie G., Free PMC Article | 12/14/2019 |
| The authors show that the antimicrobial peptide alpha-defensin is functionally sustained during nutrient deprivation because of regulation of the defensin-processing enzyme MMP7 by microbiota- and host-derived factors. Sustained Mmp7 expression requires the microbiota and is mediated by de-repression of the transcription activator Atoh1 upon attenuation of the transcriptional repressor Hes1 in intestinal epithelial cells. | Nutrient Sensing by the Intestinal Epithelium Orchestrates Mucosal Antimicrobial Defense via Translational Control of Hes1.
Liang S, Guo XK, Ou J, Huang R, Xue Q, Zhang B, Chung Y, Wu W, Dong C, Yang X, Hu X. | 11/30/2019 |
| Combined Mmp-7 Deletion and N-cadherin Mimetic (EC4-Fc) Over-Expression is associated with Aneurysm Severity. | Aneurysm Severity is Increased by Combined Mmp-7 Deletion and N-cadherin Mimetic (EC4-Fc) Over-Expression.
Lyon CA, Williams H, Bianco R, Simmonds SJ, Brown BA, Wadey KS, Smith FCT, Johnson JL, George SJ., Free PMC Article | 07/27/2019 |
| upregulating MMP7 levels may be key to remove remyelination-impairing fibronectin aggregates in multiple sclerosis lesions | MMP7 cleaves remyelination-impairing fibronectin aggregates and its expression is reduced in chronic multiple sclerosis lesions.
Wang P, Gorter RP, de Jonge JC, Nazmuddin M, Zhao C, Amor S, Hoekstra D, Baron W., Free PMC Article | 07/20/2019 |
| MMP7 shedding of syndecan-1/CXCL1 complexes functions as a checkpoint that restricts neutrophil activation at sites of epithelial injury. | Shedding of Syndecan-1/CXCL1 Complexes by Matrix Metalloproteinase 7 Functions as an Epithelial Checkpoint of Neutrophil Activation.
Gill SE, Nadler ST, Li Q, Frevert CW, Park PW, Chen P, Parks WC., Free PMC Article | 07/1/2017 |
| MMP7 exerts a restrictive role on H. pylori-induced gastric injury and the development of premalignant lesions by suppressing M1 macrophage polarization. | Matrix metalloproteinase 7 restrains Helicobacter pylori-induced gastric inflammation and premalignant lesions in the stomach by altering macrophage polarization.
Krakowiak MS, Noto JM, Piazuelo MB, Hardbower DM, Romero-Gallo J, Delgado A, Chaturvedi R, Correa P, Wilson KT, Peek RM Jr., Free PMC Article | 06/20/2015 |
| absence of MMP7 protects mice from LPS-induced intestinal permeability and lethality. | Pro-inflammatory effects of matrix metalloproteinase 7 in acute inflammation.
Vandenbroucke RE, Vanlaere I, Van Hauwermeiren F, Van Wonterghem E, Wilson C, Libert C. | 12/20/2014 |
| regulator of beta-catenin function in injured lung epithelium | Matrilysin (MMP-7) catalytic activity regulates β-catenin localization and signaling activation in lung epithelial cells.
Rims CR, McGuire JK. | 11/22/2014 |
| Angiotensin II suppresses RECK, but induces matrix metalloproteinases both in vivo and in vitro. | Angiotensin II stimulates cardiac fibroblast migration via the differential regulation of matrixins and RECK.
Siddesha JM, Valente AJ, Sakamuri SS, Yoshida T, Gardner JD, Somanna N, Takahashi C, Noda M, Chandrasekar B., Free PMC Article | 06/28/2014 |
| MMP7 regulated ciliated cell formation. | Matrix metalloproteinase-7 coordinates airway epithelial injury response and differentiation of ciliated cells.
Gharib SA, Altemeier WA, Van Winkle LS, Plopper CG, Schlesinger SY, Buell CA, Brauer R, Lee V, Parks WC, Chen P., Free PMC Article | 07/20/2013 |
| SPARC suppresses angiogenesis of gastric cancer by down-regulating the expression of VEGF and MMP-7 | Secreted protein acidic and rich in cysteine (SPARC) suppresses angiogenesis by down-regulating the expression of VEGF and MMP-7 in gastric cancer.
Zhang JL, Chen GW, Liu YC, Wang PY, Wang X, Wan YL, Zhu J, Gao HQ, Yin J, Wang W, Tian ML., Free PMC Article | 02/16/2013 |
| Protein expression levels of MMP-7, MMP-14 and ERK1/2 phosphorylation level were all elevated with the increasing pathological grades in brain glioma tissues. | Expressions of matrix metalloproteinase-7 and matrix metalloproteinase-14 associated with the activation of extracellular signal-regulated kinase1/2 in human brain gliomas of different pathological grades.
Xie H, Xue YX, Liu LB, Wang P, Liu YH, Ying HQ. | 08/25/2012 |
| levels of renal MMP-7 correlate with Wnt/beta-catenin activity. | Matrix metalloproteinase-7 as a surrogate marker predicts renal Wnt/β-catenin activity in CKD.
He W, Tan RJ, Li Y, Wang D, Nie J, Hou FF, Liu Y., Free PMC Article | 03/31/2012 |
| STAT3 plays an important role in regulation of tumor growth, invasion, and angiogenesis, which could be act by reducing MMP-7 expression in pancreatic cancer cells. | STAT3 knockdown reduces pancreatic cancer cell invasiveness and matrix metalloproteinase-7 expression in nude mice.
Li Hd, Huang C, Huang Kj, Wu Wd, Jiang T, Cao J, Feng Zz, Qiu Zj., Free PMC Article | 02/11/2012 |
| expression in pancreatic ductal adenocarcinoma cells and that MMP7 deletion limits tumor size and metastasis in mice | Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.
Fukuda A, Wang SC, Morris JP 4th, Folias AE, Liou A, Kim GE, Akira S, Boucher KM, Firpo MA, Mulvihill SJ, Hebrok M., Free PMC Article | 06/18/2011 |
| MMP-2 mediates Ang II-induced hypertension and is transcriptionally controlled by 2 other metalloproteinases, MMP-7 and TACE. | MMP-2 mediates angiotensin II-induced hypertension under the transcriptional control of MMP-7 and TACE.
Odenbach J, Wang X, Cooper S, Chow FL, Oka T, Lopaschuk G, Kassiri Z, Fernandez-Patron C. | 01/15/2011 |
| MMP-7 is involved in the cleavage of N-cadherin and modulates vascular smooth muscle cell apoptosis, and may contribute to atherosclerotic plaque development and rupture. | MMP-7 mediates cleavage of N-cadherin and promotes smooth muscle cell apoptosis.
Williams H, Johnson JL, Jackson CL, White SJ, George SJ., Free PMC Article | 09/27/2010 |
| matrilysin regulates pulmonary localization of dendritic cells that express CD103 | Matrilysin (Matrix Metalloproteinase-7) regulates anti-inflammatory and antifibrotic pulmonary dendritic cells that express CD103 (alpha(E)beta(7)-integrin).
Manicone AM, Huizar I, McGuire JK., Free PMC Article | 03/1/2010 |
| H. pylori-mediated induction of MMP-7 may serve to protect the gastric mucosa from pathophysiologic processes that promote carcinogenesis. | Matrix metalloproteinase-7 and premalignant host responses in Helicobacter pylori-infected mice.
Ogden SR, Noto JM, Allen SS, Patel DA, Romero-Gallo J, Washington MK, Fingleton B, Israel DA, Lewis ND, Wilson KT, Chaturvedi R, Zhao Z, Shyr Y, Peek RM Jr., Free PMC Article | 02/1/2010 |