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    Pias2 protein inhibitor of activated STAT 2 [ Mus musculus (house mouse) ]

    Gene ID: 17344, updated on 14-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Miz1 represses type I interferon production and limits viral clearance during influenza A virus infection.

    Miz1 represses type I interferon production and limits viral clearance during influenza A virus infection.
    Wu W, Arunagiri V, Do-Umehara HC, Chen C, Gu S, Biswas I, Ridge KM, Budinger GRS, Liu S, Liu J., Free PMC Article

    04/24/2024
    Regulation of BCR-mediated Ca[2+] mobilization by MIZ1-TMBIM4 safeguards IgG1[+] GC B cell-positive selection.

    Regulation of BCR-mediated Ca(2+) mobilization by MIZ1-TMBIM4 safeguards IgG1(+) GC B cell-positive selection.
    Zhang L, Toboso-Navasa A, Gunawan A, Camara A, Nakagawa R, Finsterbusch K, Chakravarty P, Newman R, Zhang Y, Eilers M, Wack A, Tolar P, Toellner KM, Calado DP., Free PMC Article

    04/12/2024
    Suppression of Allergic Asthma by Loss of Function of Miz1-mediated Th1 Skewing.

    Suppression of Allergic Asthma by Loss of Function of Miz1-mediated Th1 Skewing.
    Do-Umehara HC, Chen C, Zhang Q, Schleimer RP, Budinger GRS, Liu J., Free PMC Article

    09/17/2022
    A direct interaction between Pold2 and PIAS2 was confirmed by direct yeast two-hybrid.

    Identification of Pold2 as a novel interaction partner of protein inhibitor of activated STAT2.
    Zheng Y, Sheng S, Wang H, Jia X, Hu Y, Qian Y, Zhu Y, Wang J.

    05/25/2013
    Interaction of protein inhibitor of activated STAT 2 (PIAS2) with receptor of activated C kinase 1, RACK1.

    Interaction of protein inhibitor of activated STAT 2 (PIAS2) with receptor of activated C kinase 1, RACK1.
    Zheng Y, Zhang L, Jia X, Wang H, Hu Y.

    03/10/2012
    regulates interleukin-7 receptor signaling at early commitment stages of B cell differentiation

    Transcription factor miz-1 is required to regulate interleukin-7 receptor signaling at early commitment stages of B cell differentiation.
    Kosan C, Saba I, Godmann M, Herold S, Herkert B, Eilers M, Möröy T.

    05/14/2011
    study provides the first line of evidence that PIASxbeta is indispensable for osteoblast differentiation and matrix mineralization, and that this signaling molecule is located between Runx2 and osterix.

    PIASxbeta is a key regulator of osterix transcriptional activity and matrix mineralization in osteoblasts.
    Ali MM, Yoshizawa T, Ishibashi O, Matsuda A, Ikegame M, Shimomura J, Mera H, Nakashima K, Kawashima H.

    01/21/2010
    a transcriptional cofactor for TFII-I

    The SUMO ubiquitin-protein isopeptide ligase family member Miz1/PIASxbeta /Siz2 is a transcriptional cofactor for TFII-I.
    Tussie-Luna MI, Michel B, Hakre S, Roy AL.

    01/21/2010
    Miz-1 trans-actiates Nramp1 in mice

    Characterization of the murine Nramp1 promoter: requirements for transactivation by Miz-1.
    Bowen H, Lapham A, Phillips E, Yeung I, Alter-Koltunoff M, Levi BZ, Perry VH, Mann DA, Barton CH.

    01/21/2010
    role in activating natural resistance-associated protein 1 promoter

    c-Myc represses and Miz-1 activates the murine natural resistance-associated protein 1 promoter.
    Bowen H, Biggs TE, Phillips E, Baker ST, Perry VH, Mann DA, Barton CH.

    01/21/2010
    Miz-1 has a role in inducing apoptosis along with MAGE-A4

    A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells.
    Sakurai T, Itoh K, Higashitsuji H, Nagao T, Nonoguchi K, Chiba T, Fujita J.

    01/21/2010
    Results show that Miz1 is required for early embryonic development during gastrulation.

    Miz1 is required for early embryonic development during gastrulation.
    Adhikary S, Peukert K, Karsunky H, Beuger V, Lutz W, Elsässer HP, Möröy T, Eilers M., Free PMC Article

    01/21/2010
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