| MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation. | MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation.
Pantier R, Brown M, Han S, Paton K, Meek S, Montavon T, Shukeir N, McHugh T, Kelly DA, Hochepied T, Libert C, Jenuwein T, Burdon T, Bird A., Free PMC Article | 08/20/2024 |
| Methyl-CpG-binding 2 K271 lactylation-mediated M2 macrophage polarization inhibits atherosclerosis. | Methyl-CpG-binding 2 K271 lactylation-mediated M2 macrophage polarization inhibits atherosclerosis.
Chen L, Zhang M, Yang X, Wang Y, Huang T, Li X, Ban Y, Li Q, Yang Q, Zhang Y, Zheng Y, Wang D, Wang X, Shi X, Zhang M, Sun Y, Wu J., Free PMC Article | 08/9/2024 |
| Mecp2 fine-tunes quiescence exit by targeting nuclear receptors. | Mecp2 fine-tunes quiescence exit by targeting nuclear receptors.
Yang J, Zou S, Qiu Z, Lai M, Long Q, Chen H, Lai PL, Zhang S, Rao Z, Xie X, Gong Y, Liu A, Li M, Bai X., Free PMC Article | 07/31/2024 |
| Mecp2 Deficiency in Peripheral Sensory Neuron Improves Cognitive Function by Enhancing Hippocampal Dendritic Spine Densities in Mice. | Mecp2 Deficiency in Peripheral Sensory Neuron Improves Cognitive Function by Enhancing Hippocampal Dendritic Spine Densities in Mice.
Feng Y, Wang J, Liu J, Zhou Y, Jiang Y, Zhou W, Wu F, Liu X, Luo L., Free PMC Article | 07/5/2024 |
| Autoimmune and neuropsychiatric phenotypes in a Mecp2 transgenic mouse model on C57BL/6 background. | Autoimmune and neuropsychiatric phenotypes in a Mecp2 transgenic mouse model on C57BL/6 background.
Li Y, Zhang S, Tang C, Yang B, Atrooz F, Ren Z, Mohan C, Salim S, Wu T., Free PMC Article | 03/27/2024 |
| Selective Deletion of Methyl CpG Binding Protein 2 from Parvalbumin Interneurons in the Auditory Cortex Delays the Onset of Maternal Retrieval in Mice. | Selective Deletion of Methyl CpG Binding Protein 2 from Parvalbumin Interneurons in the Auditory Cortex Delays the Onset of Maternal Retrieval in Mice.
Rupert DD, Pagliaro AH, Choe J, Shea SD., Free PMC Article | 02/15/2024 |
| RIPK1 activation in Mecp2-deficient microglia promotes inflammation and glutamate release in RTT. | RIPK1 activation in Mecp2-deficient microglia promotes inflammation and glutamate release in RTT.
Cao Z, Min X, Xie X, Huang M, Liu Y, Sun W, Xu G, He M, He K, Li Y, Yuan J., Free PMC Article | 02/8/2024 |
| POMC-specific knockdown of MeCP2 leads to adverse phenotypes in mice chronically exposed to high fat diet. | POMC-specific knockdown of MeCP2 leads to adverse phenotypes in mice chronically exposed to high fat diet.
Frayre P, Ponce-Rubio K, Frayre J, Medrano J, Na ES., | 02/5/2024 |
| Tug-of-Peace: Visual Rivalry and Atypical Visual Motion Processing in MECP2 Duplication Syndrome of Autism. | Tug-of-Peace: Visual Rivalry and Atypical Visual Motion Processing in MECP2 Duplication Syndrome of Autism.
Bogatova D, Smirnakis SM, Palagina G., Free PMC Article | 01/26/2024 |
| Gut microbiome and metabolic profiles of mouse model for MeCP2 duplication syndrome. | Gut microbiome and metabolic profiles of mouse model for MeCP2 duplication syndrome.
Wu J, Hu Q, Rao X, Zhao H, Tang H, Wang Y. | 01/17/2024 |
| MeCP2 represses the activity of topoisomerase IIbeta in long neuronal genes. | MeCP2 represses the activity of topoisomerase IIβ in long neuronal genes.
Nettles SA, Ikeuchi Y, Lefton KB, Abbasi L, Erickson A, Agwu C, Papouin T, Bonni A, Gabel HW., Free PMC Article | 01/8/2024 |
| Systemic proteome phenotypes reveal defective metabolic flexibility in Mecp2 mutants. | Systemic proteome phenotypes reveal defective metabolic flexibility in Mecp2 mutants.
Zlatic SA, Werner E, Surapaneni V, Lee CE, Gokhale A, Singleton K, Duong D, Crocker A, Gentile K, Middleton F, Dalloul JM, Liu WL, Patgiri A, Tarquinio D, Carpenter R, Faundez V., | 12/28/2023 |
| Neuronal MeCP2 in the dentate gyrus regulates mossy fiber sprouting of mice with temporal lobe epilepsy. | Neuronal MeCP2 in the dentate gyrus regulates mossy fiber sprouting of mice with temporal lobe epilepsy.
Chen Y, Wu XL, Hu HB, Yang SN, Zhang ZY, Fu GL, Zhang CT, Li ZM, Wu F, Si KW, Ma YB, Ji SF, Zhou JS, Ren XY, Xiao XL, Liu JX. | 11/28/2023 |
| Spinal astrocytic MeCP2 regulates Kir4.1 for the maintenance of chronic hyperalgesia in neuropathic pain. | Spinal astrocytic MeCP2 regulates Kir4.1 for the maintenance of chronic hyperalgesia in neuropathic pain.
Ou M, Chen Y, Liu J, Zhang D, Yang Y, Shen J, Miao C, Tang SJ, Liu X, Mulkey DK, Zhu T, Zhou C., Free PMC Article | 08/11/2023 |
| Disrupting methyl-CpG-binding protein 2 expression induces the transformation of induced pluripotent stem cell cardiomyocytes into pacemaker-like cells by insulin gene enhancer binding protein 1. | Disrupting methyl-CpG-binding protein 2 expression induces the transformation of induced pluripotent stem cell cardiomyocytes into pacemaker-like cells by insulin gene enhancer binding protein 1.
Zhang W, Gu J, Shi Y, Li B, Gu X. | 07/19/2023 |
| Wild-type MECP2 expression coincides with age-dependent sensory phenotypes in a female mouse model for Rett syndrome. | Wild-type MECP2 expression coincides with age-dependent sensory phenotypes in a female mouse model for Rett syndrome.
Mykins M, Layo-Carris D, Dunn LR, Skinner DW, McBryar AH, Perez S, Shultz TR, Willems A, Lau BYB, Hong T, Krishnan K., Free PMC Article | 06/28/2023 |
| Mecp2 deletion results in profound alterations of developmental and adult functional connectivity. | Mecp2 deletion results in profound alterations of developmental and adult functional connectivity.
Rahn RM, Yen A, Chen S, Gaines SH, Bice AR, Brier LM, Swift RG, Lee L, Maloney SE, Culver JP, Dougherty JD., Free PMC Article | 06/16/2023 |
| Homeobox A9 is a novel mediator of vascular smooth muscle cell phenotypic switching and proliferation by regulating methyl-CpG binding protein 2. | Homeobox A9 is a novel mediator of vascular smooth muscle cell phenotypic switching and proliferation by regulating methyl-CpG binding protein 2.
Fu X, Fu P, Yang T, Niu T. | 06/15/2023 |
| Maternal Diabetes Deregulates the Expression of Mecp2 via miR-26b-5p in Mouse Embryonic Neural Stem Cells. | Maternal Diabetes Deregulates the Expression of Mecp2 via miR-26b-5p in Mouse Embryonic Neural Stem Cells.
Shyamasundar S, Ramya S, Kandilya D, Srinivasan DK, Bay BH, Ansari SA, Dheen ST., Free PMC Article | 06/14/2023 |
| Epigenetic reader MeCP2 repressed WIF1 boosts lung fibroblast proliferation, migration and pulmonary fibrosis. | Epigenetic reader MeCP2 repressed WIF1 boosts lung fibroblast proliferation, migration and pulmonary fibrosis.
Sha JM, Zhang RQ, Wang XC, Zhou Y, Song K, Sun H, Tu B, Tao H. | 06/1/2023 |
| Blood-Brain Barrier Integrity Is Perturbed in a Mecp2-Null Mouse Model of Rett Syndrome. | Blood-Brain Barrier Integrity Is Perturbed in a Mecp2-Null Mouse Model of Rett Syndrome.
Pepe G, Fioriniello S, Marracino F, Capocci L, Maglione V, D'Esposito M, Di Pardo A, Della Ragione F., Free PMC Article | 05/22/2023 |
| A comprehensive longitudinal study of magnetic resonance imaging identifies novel features of the Mecp2 deficient mouse brain. | A comprehensive longitudinal study of magnetic resonance imaging identifies novel features of the Mecp2 deficient mouse brain.
Carli S, Chaabane L, De Rocco G, Albizzati E, Sormonta I, Calligaro S, Bonizzi P, Frasca A, Landsberger N. | 04/19/2023 |
| A Comprehensive and Integrative Approach to MeCP2 Disease Transcriptomics. | A Comprehensive and Integrative Approach to MeCP2 Disease Transcriptomics.
Trostle AJ, Li L, Kim SY, Wang J, Al-Ouran R, Yalamanchili HK, Liu Z, Wan YW., Free PMC Article | 03/30/2023 |
| MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function. | MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function.
Bajikar SS, Anderson AG, Zhou J, Durham MA, Trostle AJ, Wan YW, Liu Z, Zoghbi HY., Free PMC Article | 03/1/2023 |
| MeCP2 Is an Epigenetic Factor That Links DNA Methylation with Brain Metabolism. | MeCP2 Is an Epigenetic Factor That Links DNA Methylation with Brain Metabolism.
Vuu YM, Roberts CT, Rastegar M., Free PMC Article | 02/28/2023 |