| The olfactory receptor Olfr78 promotes differentiation of enterochromaffin cells in the mouse colon. | The olfactory receptor Olfr78 promotes differentiation of enterochromaffin cells in the mouse colon.
Dinsart G, Leprovots M, Lefort A, Libert F, Quesnel Y, Veithen A, Vassart G, Huysseune S, Parmentier M, Garcia MI., Free PMC Article | 01/29/2024 |
| Olfactory receptor 78 is expressed in hypothalamic vasopressin/oxytocin neurons, parenchymal microglia and choroidal macrophages in mice. | Olfactory receptor 78 is expressed in hypothalamic vasopressin/oxytocin neurons, parenchymal microglia and choroidal macrophages in mice.
Nakashima A, Nakashima N, Nakashima K, Takano M., Free PMC Article | 04/23/2022 |
| Vagal neuron expression of the microbiota-derived metabolite receptor, free fatty acid receptor (FFAR3), is necessary for normal feeding behavior. | Vagal neuron expression of the microbiota-derived metabolite receptor, free fatty acid receptor (FFAR3), is necessary for normal feeding behavior.
Cook TM, Gavini CK, Jesse J, Aubert G, Gornick E, Bonomo R, Gautron L, Layden BT, Mansuy-Aubert V., Free PMC Article | 03/26/2022 |
| Olfactory receptor Olfr78 (prostate-specific G protein-coupled receptor PSGR) expression in arterioles supplying skeletal and cardiac muscles and in arterioles feeding some murine organs. | Olfactory receptor Olfr78 (prostate-specific G protein-coupled receptor PSGR) expression in arterioles supplying skeletal and cardiac muscles and in arterioles feeding some murine organs.
Mermer P, Strotmann J, Kummer W, Paddenberg R., Free PMC Article | 03/12/2022 |
| Olfactory receptor 78 modulates renin but not baseline blood pressure. | Olfactory receptor 78 modulates renin but not baseline blood pressure.
Poll BG, Xu J, Gupta K, Shubitowski TB, Pluznick JL., Free PMC Article | 03/5/2022 |
| The macrophage odorant receptor Olfr78 mediates the lactate-induced M2 phenotype of tumor-associated macrophages. | The macrophage odorant receptor Olfr78 mediates the lactate-induced M2 phenotype of tumor-associated macrophages.
Vadevoo SMP, Gunassekaran GR, Lee C, Lee N, Lee J, Chae S, Park JY, Koo J, Lee B., Free PMC Article | 12/25/2021 |
| Gut microbial short-chain fatty acids-mediated olfactory receptor 78 stimulation promotes anorexigenic gut hormone peptide YY secretion in mice. | Gut microbial short-chain fatty acids-mediated olfactory receptor 78 stimulation promotes anorexigenic gut hormone peptide YY secretion in mice.
Nishida A, Miyamoto J, Shimizu H, Kimura I. | 08/7/2021 |
| Olfactory receptor 78 regulates erythropoietin and cardiorespiratory responses to hypobaric hypoxia. | Olfactory receptor 78 regulates erythropoietin and cardiorespiratory responses to hypobaric hypoxia.
Wang B, Peng YJ, Su X, Zhang C, Nagati JS, Garcia JA, Prabhakar NR., Free PMC Article | 07/17/2021 |
| Olfr-78 is highly expressed in colon and down-regulated in colitis. | The olfactory G protein-coupled receptor (Olfr-78/OR51E2) modulates the intestinal response to colitis.
Kotlo K, Anbazhagan AN, Priyamvada S, Jayawardena D, Kumar A, Chen Y, Xia Y, Finn PW, Perkins DL, Dudeja PK, Layden BT., Free PMC Article | 08/1/2020 |
| Transgenic mice overexpressing PSGR in the prostate were reported to develop an acute inflammatory response followed by emergence of low grade prostatic intraepithelial neoplasia, whereas mice with compound PSGR overexpression and loss of PTEN exhibited accelerated formation of invasive prostate adenocarcinoma. (Review) | Prostate-Specific G-Protein Coupled Receptor, an Emerging Biomarker Regulating Inflammation and Prostate Cancer Invasion.
Rodriguez M, Siwko S, Liu M. | 10/7/2017 |
| Olfr78 is involved in the regulation of hormone secretion from such cells, as evoked by nutritional compounds | Expression of odorant receptor Olfr78 in enteroendocrine cells of the colon.
Fleischer J, Bumbalo R, Bautze V, Strotmann J, Breer H. | 08/27/2016 |
| in addition to its role in olfaction, Olfr78 acts as a hypoxia sensor in the breathing circuit by sensing lactate produced when oxygen levels decline | Oxygen regulation of breathing through an olfactory receptor activated by lactate.
Chang AJ, Ortega FE, Riegler J, Madison DV, Krasnow MA., Free PMC Article | 12/19/2015 |
| SCFAs produced by the gut microbiota modulate blood pressure via Olfr78 and Gpr41. | Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation.
Pluznick JL, Protzko RJ, Gevorgyan H, Peterlin Z, Sipos A, Han J, Brunet I, Wan LX, Rey F, Wang T, Firestein SJ, Yanagisawa M, Gordon JI, Eichmann A, Peti-Peterdi J, Caplan MJ., Free PMC Article | 05/25/2013 |