| Extracellular sodium regulates fibroblast growth factor 23 (FGF23) formation. | Extracellular sodium regulates fibroblast growth factor 23 (FGF23) formation.
Radvanyi Z, Yoo EJ, Kandasamy P, Salas-Bastos A, Monnerat S, Refardt J, Christ-Crain M, Hayashi H, Kondo Y, Jantsch J, Rubio-Aliaga I, Sommer L, Wagner CA, Hediger MA, Kwon HM, Loffing J, Pathare G., Free PMC Article | 02/7/2024 |
| ENPP1 downregulation and FGF23 upregulation in growth-related calcification of the tibial tuberosity in rats. | ENPP1 downregulation and FGF23 upregulation in growth-related calcification of the tibial tuberosity in rats.
Suito H, Fujikawa K, Ohsako M., | 01/12/2024 |
| Changes of FGF23 and hearing in chronic renal failure and their correlation analysis. | Changes of FGF23 and hearing in chronic renal failure and their correlation analysis.
Li J, Nie J, Zhou Z, Guo M, Yang Q, Yuan D, Huang J, Li R, Li Q. | 01/5/2024 |
| Klotho/FGF23 Axis Regulates Cardiomyocyte Apoptosis and Cytokine Release through ERK/MAPK Pathway. | Klotho/FGF23 Axis Regulates Cardiomyocyte Apoptosis and Cytokine Release through ERK/MAPK Pathway.
Jia Z, Liu Q, Xie Y, Wei J, Sun X, Meng F, Zhao B, Yu Z, Zhao L, Xing Z. | 09/26/2023 |
| Intact Fibroblast Growth Factor 23 Regulates Chronic Kidney Disease-Induced Myocardial Fibrosis by Activating the Sonic Hedgehog Signaling Pathway. | Intact Fibroblast Growth Factor 23 Regulates Chronic Kidney Disease-Induced Myocardial Fibrosis by Activating the Sonic Hedgehog Signaling Pathway.
Li L, Gan H., Free PMC Article | 10/1/2022 |
| Renal Clearance of Fibroblast Growth Factor-23 (FGF23) and its Fragments in Humans. | Renal Clearance of Fibroblast Growth Factor-23 (FGF23) and its Fragments in Humans.
Sharma S, Katz R, Ginsberg C, Bullen A, Vallon V, Thomson S, Moe OW, Hoofnagle AN, de Leeuw PW, Kroon AA, Houben AJHM, Ix JH., Free PMC Article | 06/18/2022 |
| The synthesis of fibroblast growth factor 23 is upregulated by homocysteine in UMR106 osteoblast-like cells. | The synthesis of fibroblast growth factor 23 is upregulated by homocysteine in UMR106 osteoblast-like cells.
Alber J, Freisinger P, Föller M. | 04/30/2022 |
| Lactic acid induces fibroblast growth factor 23 (FGF23) production in UMR106 osteoblast-like cells. | Lactic acid induces fibroblast growth factor 23 (FGF23) production in UMR106 osteoblast-like cells.
Alber J, Föller M., Free PMC Article | 03/26/2022 |
| Oral Acid Load Down-Regulates Fibroblast Growth Factor 23. | Oral Acid Load Down-Regulates Fibroblast Growth Factor 23.
Vidal A, Pineda C, Raya AI, Rios R, Espartero A, Muñoz-Castañeda JR, Rodriguez M, Aguilera-Tejero E, Lopez I., Free PMC Article | 03/19/2022 |
| Up-Regulation of Fibroblast Growth Factor 23 Gene Expression in UMR106 Osteoblast-like Cells with Reduced Viability. | Up-Regulation of Fibroblast Growth Factor 23 Gene Expression in UMR106 Osteoblast-like Cells with Reduced Viability.
Münz S, Feger M, Edemir B, Föller M., Free PMC Article | 02/26/2022 |
| Localization of fibroblast growth factor 23 protein in the rat hypothalamus. | Localization of fibroblast growth factor 23 protein in the rat hypothalamus.
Ursem SR, Diepenbroek C, Bacic V, Unmehopa UA, Eggels L, Maya-Monteiro CM, Heijboer AC, la Fleur SE., Free PMC Article | 09/18/2021 |
| Fortified phosphoruslowering treatment through administration of lanthanum protects against vascular calcification via regulation of FGF23 in chronic kidney disease. | Fortified phosphorus‑lowering treatment through administration of lanthanum protects against vascular calcification via regulation of FGF23 in chronic kidney disease.
Jiang J, Li Y, Zheng D, Wang Z, Zhou H, Liu G., Free PMC Article | 07/3/2021 |
| Fibroblast growth factor 23 decreases PDE4 expression in heart increasing the risk of cardiac arrhythmia; Klotho opposes these effects. | Fibroblast growth factor 23 decreases PDE4 expression in heart increasing the risk of cardiac arrhythmia; Klotho opposes these effects.
Lindner M, Mehel H, David A, Leroy C, Burtin M, Friedlander G, Terzi F, Mika D, Fischmeister R, Prié D. | 06/26/2021 |
| Involvement of estrogen in phosphorus-induced nephrocalcinosis through fibroblast growth factor 23. | Involvement of estrogen in phosphorus-induced nephrocalcinosis through fibroblast growth factor 23.
Takasugi S, Shioyama M, Kitade M, Nagata M, Yamaji T., Free PMC Article | 12/5/2020 |
| FGF23-mediated activation of local renin-angiotensin-aldosterone system in the heart promotes cardiac hypertrophy and fibrosis. | FGF23-Mediated Activation of Local RAAS Promotes Cardiac Hypertrophy and Fibrosis.
Böckmann I, Lischka J, Richter B, Deppe J, Rahn A, Fischer DC, Heineke J, Haffner D, Leifheit-Nestler M., Free PMC Article | 02/8/2020 |
| Klotho/FGF23 axis mediates high phosphate-induced vascular calcification in vascular smooth muscle cells via Wnt7b/beta-catenin pathway. | Klotho/FGF23 axis mediates high phosphate-induced vascular calcification in vascular smooth muscle cells via Wnt7b/β-catenin pathway.
Chen YX, Huang C, Duan ZB, Xu CY, Chen Y. | 02/8/2020 |
| PKC is a powerful regulator of FGF23 synthesis, an effect which is at least partly mediated by NFkappaB. | PKC regulates the production of fibroblast growth factor 23 (FGF23).
Bär L, Hase P, Föller M., Free PMC Article | 01/11/2020 |
| FGF-23 could inhibit signaling transduction of ERK/MAPK pathway and accelerate the secretion of PTH in rats with secondary hyperparathyroidism. | Effects of FGF-23-mediated ERK/MAPK signaling pathway on parathyroid hormone secretion of parathyroid cells in rats with secondary hyperparathyroidism.
Chen XJ, Chen X, Wu WJ, Zhou Q, Gong XH, Shi BM. | 10/5/2019 |
| These results suggest that intravenous Ca loading might stimulate FGF23 production from bone in normal and uremic rats | Effect of Continuous Intravenous Calcium Loading on Fibroblast Growth Factor 23 in Normal and Uremic Rats.
Shikida Y, Mizobuchi M, Inoue T, Hamada T, Ogata H, Koiwa F, Shibata T. | 09/14/2019 |
| in hypertension, serum level increased with heart weight and left ventricular hypertrophy progression | Changes in serum and intracardiac fibroblast growth factor 23 during the progression of left ventricular hypertrophy in hypertensive model rats.
Fujii H, Watanabe K, Kono K, Goto S, Watanabe S, Nishi S. | 09/14/2019 |
| FGF23 may serve as a novel biomarker for renal osteodystrophy. | Fibroblast growth factor-23 may serve as a novel biomarker for renal osteodystrophy progression.
Liu SY, Zhang DD, Wu YF, Luo HH, Jiang GM, Xu Y, Wu Y, Xia X, Wei W, Hu B, Hu P. | 03/9/2019 |
| Results show that TGF-beta2 enhanced gene expression and protein synthesis of FGF23 in osteoblast-like cells. The effect was paralleled by enhanced SOCE which was required for the full effect on Fgf23 gene expression. TGF-beta2-induced FGF23 formation presumably contributes to high plasma FGF23 levels in acute and chronic diseases. | The production of fibroblast growth factor 23 is controlled by TGF-β2.
Feger M, Hase P, Zhang B, Hirche F, Glosse P, Lang F, Föller M., Free PMC Article | 02/2/2019 |
| Increases in plasma erythropoietin and erythropoietin receptor activation are mechanisms implicated in the increase of plasma FGF23 in acute kidney injury. | Erythropoietin induces bone marrow and plasma fibroblast growth factor 23 during acute kidney injury.
Toro L, Barrientos V, León P, Rojas M, Gonzalez M, González-Ibáñez A, Illanes S, Sugikawa K, Abarzúa N, Bascuñán C, Arcos K, Fuentealba C, Tong AM, Elorza AA, Pinto ME, Alzamora R, Romero C, Michea L. | 12/22/2018 |
| The investigation demonstrated that the serum levels of FGF23 and the phosphorylation levels of JAK2, STAT1, and STAT3 were up-regulated in the ovariectomy (OVX) + NVP-BGJ398 group while were down-regulated in the OVX + Anti-FGF23 group than that in the OVX group. | The participation of fibroblast growth factor 23 (FGF23) in the progression of osteoporosis via JAK/STAT pathway.
Xu L, Zhang L, Zhang H, Yang Z, Qi L, Wang Y, Ren S. | 12/22/2018 |
| In chronic kidney disease (CKD) rat models, FGF23 mRNA is expressed in the kidney, and the FGF23 protein is expressed at high levels in osteopontin-positive renal tubule epithelium cells likely via TGFbeta1 stimulation. FGF23 produced in the kidney might contribute to P metabolism in subjects with CKD. | Fibroblast growth factor 23 is upregulated in the kidney in a chronic kidney disease rat model.
Sugiura H, Matsushita A, Futaya M, Teraoka A, Akiyama KI, Usui N, Nagano N, Nitta K, Tsuchiya K., Free PMC Article | 06/23/2018 |