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    Lepr leptin receptor [ Mus musculus (house mouse) ]

    Gene ID: 16847, updated on 5-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Cell-Type-Specific Expression of Leptin Receptors in the Mouse Forebrain.

    Cell-Type-Specific Expression of Leptin Receptors in the Mouse Forebrain.
    Canepa CR, Kara JA, Lee CC., Free PMC Article

    10/3/2024
    Involvement of ObRb receptor, nitric oxide, and BKCa channel signaling pathways in leptin-induced relaxation of pregnant mouse uterus.

    Involvement of ObRb receptor, nitric oxide, and BK(Ca) channel signaling pathways in leptin-induced relaxation of pregnant mouse uterus.
    Kishor Kumar DG, Pashupathi M, Vaidhya A, Ravi Prakash G, Bramhane A, Panigrahi M, Karikalan M, Lingaraju MC, Manickam K, Singh TU, Parida S.

    08/28/2024
    Leptin Receptor Deficiency Impairs Lymph Node Development and Adaptive Immune Response.

    Leptin Receptor Deficiency Impairs Lymph Node Development and Adaptive Immune Response.
    Cardani-Boulton A, Sung SJ, Petri WA Jr, Hahn YS, Braciale TJ.,

    03/6/2024
    Influence of leptin and its receptors on individuals under chronic social stress behavior.

    Influence of leptin and its receptors on individuals under chronic social stress behavior.
    Mélo RMF, Barbosa RS, Ozório VL, Oliveira GM, Horita SIM, Henriques-Pons A, Araújo-Jorge TC, Fragoso VMS., Free PMC Article

    02/29/2024
    Immunomodulatory leptin receptor[+] sympathetic perineurial barrier cells protect against obesity by facilitating brown adipose tissue thermogenesis.

    Immunomodulatory leptin receptor(+) sympathetic perineurial barrier cells protect against obesity by facilitating brown adipose tissue thermogenesis.
    Haberman ER, Sarker G, Arús BA, Ziegler KA, Meunier S, Martínez-Sánchez N, Freibergerová E, Yilmaz-Özcan S, Fernández-González I, Zentai C, O'Brien CJO, Grainger DE, Sidarta-Oliveira D, Chakarov S, Raimondi A, Iannacone M, Engelhardt S, López M, Ginhoux F, Domingos AI.

    01/15/2024
    ANGPTL4 binds to the leptin receptor to regulate ectopic bone formation.

    ANGPTL4 binds to the leptin receptor to regulate ectopic bone formation.
    Hu H, Luo S, Lai P, Lai M, Mao L, Zhang S, Jiang Y, Wen J, Zhou W, Liu X, Wang L, Huang M, Hu Y, Zhao X, Xia L, Zhou W, Jiang Y, Zou Z, Liu A, Guo B, Bai X., Free PMC Article

    01/4/2024
    The leptin receptor has no role in delta-cell control of beta-cell function in the mouse.

    The leptin receptor has no role in delta-cell control of beta-cell function in the mouse.
    Zhang J, Katada K, Mosleh E, Yuhas A, Peng G, Golson ML., Free PMC Article

    10/30/2023
    Altered function of arcuate leptin receptor expressing neuropeptide Y neurons depending on energy balance.

    Altered function of arcuate leptin receptor expressing neuropeptide Y neurons depending on energy balance.
    Lee NJ, Oraha J, Qi Y, Enriquez RF, Tasan R, Herzog H., Free PMC Article

    09/11/2023
    Leptin/obR signaling exacerbates obesity-related neutrophilic airway inflammation through inflammatory M1 macrophages.

    Leptin/obR signaling exacerbates obesity-related neutrophilic airway inflammation through inflammatory M1 macrophages.
    Wang Y, Wan R, Hu C., Free PMC Article

    08/3/2023
    Metabolic rewiring and epigenetic reprogramming in leptin receptor-deficient db/db diabetic nephropathy mice.

    Metabolic rewiring and epigenetic reprogramming in leptin receptor-deficient db/db diabetic nephropathy mice.
    Sarwar MS, Cheng D, Peter RM, Shannar A, Chou P, Wang L, Wu R, Sargsyan D, Goedken M, Wang Y, Su X, Hart RP, Kong AN.

    07/3/2023
    Deletion of endothelial leptin receptors in mice promotes diet-induced obesity.

    Deletion of endothelial leptin receptors in mice promotes diet-induced obesity.
    Gogiraju R, Witzler C, Shahneh F, Hubert A, Renner L, Bochenek ML, Zifkos K, Becker C, Thati M, Schäfer K., Free PMC Article

    05/31/2023
    Endothelial and Leptin Receptor[+] cells promote the maintenance of stem cells and hematopoiesis in early postnatal murine bone marrow.

    Endothelial and Leptin Receptor(+) cells promote the maintenance of stem cells and hematopoiesis in early postnatal murine bone marrow.
    Kara N, Xue Y, Zhao Z, Murphy MM, Comazzetto S, Lesser A, Du L, Morrison SJ., Free PMC Article

    03/21/2023
    LepRb+ cell-specific deletion of Slug mitigates obesity and nonalcoholic fatty liver disease in mice.

    LepRb+ cell-specific deletion of Slug mitigates obesity and nonalcoholic fatty liver disease in mice.
    Kim MH, Li Y, Zheng Q, Jiang L, Myers MG Jr, Wu WS, Rui L., Free PMC Article

    03/3/2023
    Regional specific effect of saturated vs unsaturated fat on leptin receptor signalling in mice brain areas regulating feeding.

    Regional specific effect of saturated vs unsaturated fat on leptin receptor signalling in mice brain areas regulating feeding.
    Fernández-Felipe J, López LL, Cano V, Sánchez-Hita E, Belén Sanz A, Chowen JA, Del Olmo N, Ruiz-Gayo M, Merino B.

    12/24/2022
    Endothelial leptin receptor is dispensable for leptin-induced sympatho-activation and hypertension in male mice.

    Endothelial leptin receptor is dispensable for leptin-induced sympatho-activation and hypertension in male mice.
    Atawia RT, Faulkner JL, Mehta V, Austin A, Jordan CR, Kennard S, Belin de Chantemèle EJ., Free PMC Article

    10/22/2022
    Conditional knockout of leptin receptor in the female reproductive tract reduces fertility due to parturition defects in mice.

    Conditional knockout of leptin receptor in the female reproductive tract reduces fertility due to parturition defects in mice.
    Pennington KA, Oestreich AK, Cataldo KH, Fogliatti CM, Lightner C, Lydon JP, Schulz LC.

    08/27/2022
    Leptin receptor-expressing pericytes mediate access of hypothalamic feeding centers to circulating leptin.

    Leptin receptor-expressing pericytes mediate access of hypothalamic feeding centers to circulating leptin.
    Butiaeva LI, Slutzki T, Swick HE, Bourguignon C, Robins SC, Liu X, Storch KF, Kokoeva MV.

    04/2/2022
    A novel compound heterozygous leptin receptor mutation causes more severe obesity than in Lepr(db/db) mice.

    A novel compound heterozygous leptin receptor mutation causes more severe obesity than in Lepr(db/db) mice.
    Berger C, Heyne HO, Heiland T, Dommel S, Höfling C, Guiu-Jurado E, Lorenz J, Roßner S, Dannemann M, Kelso J, Kovacs P, Blüher M, Klöting N., Free PMC Article

    03/26/2022
    Leptin Receptor Expression in GABAergic Cells is Not Sufficient to Normalize Metabolism and Reproduction in Mice.

    Leptin Receptor Expression in GABAergic Cells is Not Sufficient to Normalize Metabolism and Reproduction in Mice.
    Quaresma PGF, Wasinski F, Mansano NS, Furigo IC, Teixeira PDS, Gusmao DO, Frazao R, Donato J.

    01/15/2022
    Leptin signaling in vagal afferent neurons supports the absorption and storage of nutrients from high-fat diet.

    Leptin signaling in vagal afferent neurons supports the absorption and storage of nutrients from high-fat diet.
    Huang KP, Goodson ML, Vang W, Li H, Page AJ, Raybould HE., Free PMC Article

    01/8/2022
    Exploring the endocannabinoidome in genetically obese (ob/ob) and diabetic (db/db) mice: Links with inflammation and gut microbiota.

    Exploring the endocannabinoidome in genetically obese (ob/ob) and diabetic (db/db) mice: Links with inflammation and gut microbiota.
    Suriano F, Manca C, Flamand N, Depommier C, Van Hul M, Delzenne NM, Silvestri C, Cani PD, Di Marzo V.

    01/1/2022
    Leptin receptor stimulation in late pregnant mouse uterine tissue inhibits spontaneous contractions by increasing NO and cGMP.

    Leptin receptor stimulation in late pregnant mouse uterine tissue inhibits spontaneous contractions by increasing NO and cGMP.
    Srinivasan G, Parida S, Pavithra S, Panigrahi M, Sahoo M, Singh TU, Madhu CL, Manickam K, Shyamkumar TS, Kumar D, Mishra SK.

    01/1/2022
    Leptin Receptor Expressing Neurons in the Substantia Nigra Regulate Locomotion, and in The Ventral Tegmental Area Motivation and Feeding.

    Leptin Receptor Expressing Neurons in the Substantia Nigra Regulate Locomotion, and in The Ventral Tegmental Area Motivation and Feeding.
    de Vrind VAJ, van 't Sant LJ, Rozeboom A, Luijendijk-Berg MCM, Omrani A, Adan RAH., Free PMC Article

    12/25/2021
    Deletion of growth hormone receptor in hypothalamic neurons affects the adaptation capacity to aerobic exercise.

    Deletion of growth hormone receptor in hypothalamic neurons affects the adaptation capacity to aerobic exercise.
    Pedroso JAB, Dos Santos LBP, Furigo IC, Spagnol AR, Wasinski F, List EO, Kopchick JJ, Donato J Jr., Free PMC Article

    11/22/2021
    Leptin signalling on arcuate NPY neurones controls adiposity independent of energy balance or diet composition.

    Leptin signalling on arcuate NPY neurones controls adiposity independent of energy balance or diet composition.
    Zhang L, Reed F, Herzog H.

    10/30/2021
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