| Engineering Pancreatic Islets to Transiently Codisplay on Their Surface Thrombomodulin and CD47 Immunomodulatory Proteins as a Means of Mitigating Instant Blood-Mediated Inflammatory Reaction following Intraportal Transplantation. | Engineering Pancreatic Islets to Transiently Codisplay on Their Surface Thrombomodulin and CD47 Immunomodulatory Proteins as a Means of Mitigating Instant Blood-Mediated Inflammatory Reaction following Intraportal Transplantation.
Turan A, Tarique M, Zhang L, Kazmi S, Ulker V, Tedla MG, Badal D, Yolcu ES, Shirwan H., | 06/11/2024 |
| Expression of a mutant CD47 protects against phagocytosis without inducing cell death or inhibiting angiogenesis. | Expression of a mutant CD47 protects against phagocytosis without inducing cell death or inhibiting angiogenesis.
Xu L, Wang X, Zhang T, Meng X, Zhao W, Pi C, Yang YG., Free PMC Article | 03/22/2024 |
| Galectin-3 Cooperates with CD47 to Suppress Phagocytosis and T-cell Immunity in Gastric Cancer Peritoneal Metastases. | Galectin-3 Cooperates with CD47 to Suppress Phagocytosis and T-cell Immunity in Gastric Cancer Peritoneal Metastases.
Fan Y, Song S, Li Y, Dhar SS, Jin J, Yoshimura K, Yao X, Wang R, Scott AW, Pizzi MP, Wu J, Ma L, Calin GA, Hanash S, Wang L, Curran M, Ajani JA., Free PMC Article | 02/13/2024 |
| AMPK-mediated CD47 H3K4 methylation promotes phagocytosis evasion of glioma stem cells post-radiotherapy. | AMPK-mediated CD47 H3K4 methylation promotes phagocytosis evasion of glioma stem cells post-radiotherapy.
Sun T, Liu B, Cao Y, Li Y, Cai L, Yang W. | 02/6/2024 |
| alpha5-nAChR/STAT3/CD47 axis contributed to nicotine-related lung adenocarcinoma progression and immune escape. | α5-nAChR/STAT3/CD47 axis contributed to nicotine-related lung adenocarcinoma progression and immune escape.
Kang G, Jiao Y, Pan P, Fan H, Li Q, Li X, Li J, Wang Y, Jia Y, Wang J, Sun H, Ma X. | 01/10/2024 |
| CD47 and PD-L1 overexpression in proliferating human hepatocytes attenuated immune responses and ameliorated acute liver injury in mice. | CD47 and PD-L1 overexpression in proliferating human hepatocytes attenuated immune responses and ameliorated acute liver injury in mice.
Ma C, Cao H, Sun Z, Deng Q, Liu W, Xin Y, Qiao S, Cen J, Shu Y, Qi K, Han L, Zhang L, Pan G. | 12/5/2023 |
| CD47 masks pro-phagocytic ligands in cis on tumor cells to suppress antitumor immunity. | CD47 masks pro-phagocytic ligands in cis on tumor cells to suppress antitumor immunity.
Tang Z, Zhong MC, Qian J, Galindo CC, Davidson D, Li J, Zhao Y, Hui E, Veillette A. | 12/5/2023 |
| Sex differences in the effects of brown adipocyte CD47 deficiency on age-related weight change and glucose homeostasis. | Sex differences in the effects of brown adipocyte CD47 deficiency on age-related weight change and glucose homeostasis.
Li D, Gwag T, Wang S., Free PMC Article | 11/22/2023 |
| A metabolic role for CD47 in pancreatic beta cell insulin secretion and islet transplant outcomes. | A metabolic role for CD47 in pancreatic β cell insulin secretion and islet transplant outcomes.
Ghimire K, Kale A, Li J, Julovi SM, O'Connell P, Grey ST, Hawthorne WJ, Gunton JE, Rogers NM. | 11/3/2023 |
| Deletion of CD47 from Schwann cells and macrophages hastens myelin disruption/dismantling and scavenging in Schwann cells and augments myelin debris phagocytosis in macrophages. | Deletion of CD47 from Schwann cells and macrophages hastens myelin disruption/dismantling and scavenging in Schwann cells and augments myelin debris phagocytosis in macrophages.
Gitik M, Elberg G, Reichert F, Tal M, Rotshenker S., Free PMC Article | 11/1/2023 |
| CD47 promotes peripheral T cell survival by preventing dendritic cell-mediated T cell necroptosis. | CD47 promotes peripheral T cell survival by preventing dendritic cell-mediated T cell necroptosis.
Komori S, Saito Y, Nishimura T, Respatika D, Endoh H, Yoshida H, Sugihara R, Iida-Norita R, Afroj T, Takai T, Oduori OS, Nitta E, Kotani T, Murata Y, Kaneko Y, Nitta R, Ohnishi H, Matozaki T., Free PMC Article | 08/9/2023 |
| CD47 Activation by Thrombospondin-1 in Lymphatic Endothelial Cells Suppresses Lymphangiogenesis and Promotes Atherosclerosis. | CD47 Activation by Thrombospondin-1 in Lymphatic Endothelial Cells Suppresses Lymphangiogenesis and Promotes Atherosclerosis.
Singla B, Aithbathula RV, Pervaiz N, Kathuria I, Swanson M, Ekuban FA, Ahn W, Park F, Gyamfi M, Cherian-Shaw M, Singh UP, Kumar S., Free PMC Article | 06/28/2023 |
| Blocking the CD47-SIRPalpha interaction reverses the disease phenotype in a polycythemia vera mouse model. | Blocking the CD47-SIRPα interaction reverses the disease phenotype in a polycythemia vera mouse model.
Lysenko V, Schürch PM, Tuzlak S, van Wijk NW, Kovtonyuk LV, Becher B, Manz MG, Kreutmair S, Theocharides APA., Free PMC Article | 06/13/2023 |
| Blockade of CD47 function attenuates restenosis by promoting smooth muscle cell efferocytosis and inhibiting their migration and proliferation. | Blockade of CD47 function attenuates restenosis by promoting smooth muscle cell efferocytosis and inhibiting their migration and proliferation.
Govatati S, Pichavaram P, Kumar R, Rao GN., Free PMC Article | 05/9/2023 |
| The DNA damage response pathway regulates the expression of the immune checkpoint CD47. | The DNA damage response pathway regulates the expression of the immune checkpoint CD47.
Ghantous L, Volman Y, Hefez R, Wald O, Stern E, Friehmann T, Chajut A, Bremer E, Elhalel MD, Rachmilewitz J., Free PMC Article | 03/9/2023 |
| Senescent cells suppress macrophage-mediated corpse removal via upregulation of the CD47-QPCT/L axis. | Senescent cells suppress macrophage-mediated corpse removal via upregulation of the CD47-QPCT/L axis.
Schloesser D, Lindenthal L, Sauer J, Chung KJ, Chavakis T, Griesser E, Baskaran P, Maier-Habelsberger U, Fundel-Clemens K, Schlotthauer I, Watson CK, Swee LK, Igney F, Park JE, Huber-Lang MS, Thomas MJ, El Kasmi KC, Murray PJ., Free PMC Article | 03/8/2023 |
| CD47-Dependent Regulation of Immune Checkpoint Gene Expression and MYCN mRNA Splicing in Murine CD8 and Jurkat T Cells. | CD47-Dependent Regulation of Immune Checkpoint Gene Expression and MYCN mRNA Splicing in Murine CD8 and Jurkat T Cells.
Kaur S, Awad D, Finney RP, Meyer TJ, Singh SP, Cam MC, Karim BO, Warner AC, Roberts DD., Free PMC Article | 02/16/2023 |
| CD47 halts Ptpn6-deficient neutrophils from provoking lethal inflammation. | CD47 halts Ptpn6-deficient neutrophils from provoking lethal inflammation.
Mazgaeen L, Yorek M, Saini S, Vogel P, Meyerholz DK, Kanneganti TD, Gurung P., Free PMC Article | 01/21/2023 |
| Oncogenic KRAS signaling drives evasion of innate immune surveillance in lung adenocarcinoma by activating CD47. | Oncogenic KRAS signaling drives evasion of innate immune surveillance in lung adenocarcinoma by activating CD47.
Hu H, Cheng R, Wang Y, Wang X, Wu J, Kong Y, Zhan S, Zhou Z, Zhu H, Yu R, Liang G, Wang Q, Zhu X, Zhang CY, Yin R, Yan C, Chen X., Free PMC Article | 01/21/2023 |
| Neuronal signal-regulatory protein alpha drives microglial phagocytosis by limiting microglial interaction with CD47 in the retina. | Neuronal signal-regulatory protein alpha drives microglial phagocytosis by limiting microglial interaction with CD47 in the retina.
Jiang D, Burger CA, Akhanov V, Liang JH, Mackin RD, Albrecht NE, Andrade P, Schafer DP, Samuel MA., Free PMC Article | 12/24/2022 |
| Metabolic control of CD47 expression through LAT2-mediated amino acid uptake promotes tumor immune evasion. | Metabolic control of CD47 expression through LAT2-mediated amino acid uptake promotes tumor immune evasion.
Wang Z, Li B, Li S, Lin W, Wang Z, Wang S, Chen W, Shi W, Chen T, Zhou H, Yinwang E, Zhang W, Mou H, Chai X, Zhang J, Lu Z, Ye Z., Free PMC Article | 11/5/2022 |
| Mitochondria transfer mediates stress erythropoiesis by altering the bioenergetic profiles of early erythroblasts through CD47. | Mitochondria transfer mediates stress erythropoiesis by altering the bioenergetic profiles of early erythroblasts through CD47.
Yang C, Yokomori R, Chua LH, Tan SH, Tan DQ, Miharada K, Sanda T, Suda T., Free PMC Article | 10/15/2022 |
| CD47 Promotes Autoimmune Valvular Carditis by Impairing Macrophage Efferocytosis and Enhancing Cytokine Production. | CD47 Promotes Autoimmune Valvular Carditis by Impairing Macrophage Efferocytosis and Enhancing Cytokine Production.
Meier LA, Faragher JL, Osinski V, Auger JL, Voeller R, Marath A, Binstadt BA., Free PMC Article | 08/6/2022 |
| CD47 Binding on Vascular Endothelial Cells Inhibits IL-17-Mediated Leukocyte Adhesion. | CD47 Binding on Vascular Endothelial Cells Inhibits IL-17-Mediated Leukocyte Adhesion.
Soriano-Romaní L, Mir FA, Singh N, Chin I, Hafezi-Moghadam A, Masli S., Free PMC Article | 06/11/2022 |
| SIRPalpha - CD47 axis regulates dendritic cell-T cell interactions and TCR activation during T cell priming in spleen. | SIRPα - CD47 axis regulates dendritic cell-T cell interactions and TCR activation during T cell priming in spleen.
Autio A, Wang H, Velázquez F, Newton G, Parkos CA, Engel P, Engelbertsen D, Lichtman AH, Luscinskas FW., Free PMC Article | 04/30/2022 |