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    Itgb3 integrin beta 3 [ Mus musculus (house mouse) ]

    Gene ID: 16416, updated on 8-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Cooperation Between Platelet beta1 and beta3 Integrins in the Arrest of Bleeding Under Inflammatory Conditions in Mice-Brief Report.

    Cooperation Between Platelet β1 and β3 Integrins in the Arrest of Bleeding Under Inflammatory Conditions in Mice-Brief Report.
    Janus-Bell E, Receveur N, Mercier L, Mouriaux C, Magnenat S, Reiser J, Lanza F, Hechler B, Ho-Tin-Noé B, Mangin PH.

    10/2/2024
    Integrin beta3 enhances glycolysis and increases lactate production in endometriosis.

    Integrin β3 enhances glycolysis and increases lactate production in endometriosis.
    Gao X, Shao W, Wang J, Gao H, Zhang X, Xia C, Li M, Liu S.

    09/9/2024
    PEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3.

    PEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3.
    Sun JT, Wang ZM, Zhou LH, Yang TT, Zhao D, Bao YL, Wang SB, Gu LF, Chen JW, Shan TK, Wei TW, Wang H, Wang QM, Kong XQ, Xie LP, Gu AH, Zhao Y, Chen F, Ji Y, Cui YQ, Wang LS., Free PMC Article

    07/23/2024
    Potential Mechanism of Platelet GPIIb/IIIa and Fibrinogen on Retinal Vein Occlusion.

    Potential Mechanism of Platelet GPIIb/IIIa and Fibrinogen on Retinal Vein Occlusion.
    Ren H, Sun Y, Li Y, Yuan X, Jiang B, Zhang W, Liu G, Lu P.

    07/15/2024
    Integrin alphavbeta3 Limits Cytokine Production by Plasmacytoid Dendritic Cells and Restricts TLR-Driven Autoimmunity.

    Integrin αvβ3 Limits Cytokine Production by Plasmacytoid Dendritic Cells and Restricts TLR-Driven Autoimmunity.
    Lorant AK, Yoshida AE, Gilbertson EA, Chu T, Stefani C, Acharya M, Hamerman JA, Lacy-Hulbert A.,

    05/28/2024
    Upregulation of Integrin beta-3 in astrocytes upon Alzheimer's disease progression in the 5xFAD mouse model.

    Upregulation of Integrin beta-3 in astrocytes upon Alzheimer's disease progression in the 5xFAD mouse model.
    Ivanova M, Belaya I, Kucháriková N, de Sousa Maciel I, Saveleva L, Alatalo A, Juvonen I, Thind N, Andrès C, Lampinen R, Chew S, Kanninen KM.

    02/12/2024
    Role of Formyl Peptide Receptors and beta-Arrestin-1 in suPAR Signal Transduction in Mouse Podocytes: Interactions with alphaVbeta3-Integrin.

    Role of Formyl Peptide Receptors and β-Arrestin-1 in suPAR Signal Transduction in Mouse Podocytes: Interactions with αVβ3-Integrin.
    Kim EY, Dryer SE., Free PMC Article

    02/9/2024
    CD61 identifies a superior population of aged murine HSCs and is required to preserve quiescence and self-renewal.

    CD61 identifies a superior population of aged murine HSCs and is required to preserve quiescence and self-renewal.
    Skinder N, Sanz Fernández I, Dethmers-Ausema A, Weersing E, de Haan G., Free PMC Article

    01/4/2024
    Matrix stiffness controls megakaryocyte adhesion, fibronectin fibrillogenesis, and proplatelet formation through Itgbeta3.

    Matrix stiffness controls megakaryocyte adhesion, fibronectin fibrillogenesis, and proplatelet formation through Itgβ3.
    Guinard I, Nguyen T, Brassard-Jollive N, Weber J, Ruch L, Reininger L, Brouard N, Eckly A, Collin D, Lanza F, Léon C., Free PMC Article

    10/30/2023
    Milk osteopontin promotes intestinal development by up-regulating the expression of integrin alphavbeta3 and CD44.

    Milk osteopontin promotes intestinal development by up-regulating the expression of integrin αvβ3 and CD44.
    Jiang R, Lo J, Prell C, Lönnerdal B.

    05/28/2023
    Integrin beta3-Mediated Cell Senescence Associates with Gut Inflammation and Intestinal Degeneration in Models of Alzheimer's Disease.

    Integrin β3-Mediated Cell Senescence Associates with Gut Inflammation and Intestinal Degeneration in Models of Alzheimer's Disease.
    Tun X, Wang EJ, Gao Z, Lundberg K, Xu R, Hu D., Free PMC Article

    03/31/2023
    Integrin beta3 Mediates Sepsis and Mechanical Ventilation-Associated Pulmonary Fibrosis Through Glycometabolic Reprogramming.

    Integrin β3 Mediates Sepsis and Mechanical Ventilation-Associated Pulmonary Fibrosis Through Glycometabolic Reprogramming.
    Mei S, Tang R, Hu Y, Feng J, Xu Q, Zhou Y, Zhong H, Gao Y, He Z, Xing S.

    03/2/2023
    SHIP1 Controls Internal Platelet Contraction and alphaIIbbeta3 Integrin Dynamics in Early Platelet Activation.

    SHIP1 Controls Internal Platelet Contraction and α(IIb)β(3) Integrin Dynamics in Early Platelet Activation.
    Severin S, Consonni A, Chicanne G, Allart S, Payrastre B, Gratacap MP., Free PMC Article

    01/28/2023
    Integrin beta3 in forebrain Emx1-expressing cells regulates repetitive self-grooming and sociability in mice.

    Integrin β3 in forebrain Emx1-expressing cells regulates repetitive self-grooming and sociability in mice.
    Lopuch AJ, Swinehart BD, Widener EL, Holley ZL, Bland KM, Handwerk CJ, Brett CA, Cook HN, Kalinowski AR, Rodriguez HV, Song MI, Vidal GS., Free PMC Article

    05/14/2022
    alphaVbeta3 Integrin Expression Is Essential for Replication of Mosquito and Tick-Borne Flaviviruses in Murine Fibroblast Cells.

    αVβ3 Integrin Expression Is Essential for Replication of Mosquito and Tick-Borne Flaviviruses in Murine Fibroblast Cells.
    Reis VPD, Keller M, Schmidt K, Ulrich RG, Groschup MH., Free PMC Article

    02/19/2022
    Integrin beta3 overexpression contributes to podocyte injury through inhibiting RhoA/YAP signaling pathway.

    Integrin β3 overexpression contributes to podocyte injury through inhibiting RhoA/YAP signaling pathway.
    Li Z, Lian Z, Ma J, Zhang L, Lian X, Liu S, Xie J, Feng Z, Lin T, Zhang H, Liang X., Free PMC Article

    11/13/2021
    Itgb3-integrin-deficient mice may not be a sufficient model for patients with Glanzmann thrombasthenia.

    Itgb3-integrin-deficient mice may not be a sufficient model for patients with Glanzmann thrombasthenia.
    Li D, Peng J, Li T, Liu Y, Chen M, Shi X., Free PMC Article

    10/23/2021
    Integrin beta3 organizes dendritic complexity of cerebral cortical pyramidal neurons along a tangential gradient.

    Integrin β3 organizes dendritic complexity of cerebral cortical pyramidal neurons along a tangential gradient.
    Swinehart BD, Bland KM, Holley ZL, Lopuch AJ, Casey ZO, Handwerk CJ, Vidal GS., Free PMC Article

    09/4/2021
    Protective effect of MAPK signaling pathway mediated by ITGB3 gene silencing on myocardial ischemia-reperfusion injury in mice and its mechanism.

    Protective effect of MAPK signaling pathway mediated by ITGB3 gene silencing on myocardial ischemia-reperfusion injury in mice and its mechanism.
    Wang MC, Wang D, Lu YH, Li ZH, Jing HY.

    07/3/2021
    IL1RN promotes osteoblastic differentiation via interacting with ITGB3 in osteoporosis.

    IL1RN promotes osteoblastic differentiation via interacting with ITGB3 in osteoporosis.
    Zou Z, Liu R, Wang Y, Xing Y, Shi Z, Wang K, Dong D.

    06/12/2021
    Migfilin supports hemostasis and thrombosis through regulating platelet alphaIIbbeta3 outside-in signaling.

    Migfilin supports hemostasis and thrombosis through regulating platelet αIIbβ3 outside-in signaling.
    Zhou Y, Hu M, Chen X, Wang S, Li J, Sa L, Li L, Huang J, Cheng H, Hu H., Free PMC Article

    05/8/2021
    The Commensal Microbiota Enhances ADP-Triggered Integrin alphaIIbbeta3 Activation and von Willebrand Factor-Mediated Platelet Deposition to Type I Collagen.

    The Commensal Microbiota Enhances ADP-Triggered Integrin α(IIb)β(3) Activation and von Willebrand Factor-Mediated Platelet Deposition to Type I Collagen.
    Kiouptsi K, Jäckel S, Wilms E, Pontarollo G, Winterstein J, Karwot C, Groß K, Jurk K, Reinhardt C., Free PMC Article

    02/27/2021
    The DEL-1/beta3 integrin axis promotes regulatory T cell responses during inflammation resolution.

    The DEL-1/β3 integrin axis promotes regulatory T cell responses during inflammation resolution.
    Li X, Colamatteo A, Kalafati L, Kajikawa T, Wang H, Lim JH, Bdeir K, Chung KJ, Yu X, Fusco C, Porcellini A, De Simone S, Matarese G, Chavakis T, De Rosa V, Hajishengallis G., Free PMC Article

    02/20/2021
    the decline of estradiol and progesterone downregulates the expression of alphav and beta3 integrins which were influenced by chlorpyrifos exposure

    Chlorpyrifos effects on integrin alpha v and beta 3 in implantation window phase.
    Gheibi P, Eftekhari Z, Doroud D, Parivar K.

    08/1/2020
    Hypertriglyceridemia is found in both integrin beta3-deficient mice. beta3 functions as an adapter in the formation of protein kinase D/beta3/LPL complex that is required for beta3-mediated LPL secretion and triglyceride metabolism.

    Integrin β3 Deficiency Results in Hypertriglyceridemia via Disrupting LPL (Lipoprotein Lipase) Secretion.
    Xiao B, Mao J, Sun B, Zhang W, Wang Y, Wang P, Ruan Z, Xi W, Li H, Zhou J, Lu Y, Ding Q, Wang X, Liu J, Yan J, Luo C, Shi X, Yang R, Xi X.

    07/18/2020
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