| Acyl-coenzyme a binding protein (ACBP) - a risk factor for cancer diagnosis and an inhibitor of immunosurveillance. | Acyl-coenzyme a binding protein (ACBP) - a risk factor for cancer diagnosis and an inhibitor of immunosurveillance.
Montégut L, Liu P, Zhao L, Pérez-Lanzón M, Chen H, Mao M, Zhang S, Derosa L, Naour JL, Lambertucci F, Mingoia S, Nogueira-Recalde U, Mena-Osuna R, Herranz-Montoya I, Djouder N, Baulande S, Pan H, Joseph A, Messaoudene M, Routy B, Fidelle M, Ben Ahmed T, Caron O, Busson P, Boulate D, Deschasaux-Tanguy M, Arnault N, Pol JG, Piaggio E, Touvier M, Zitvogel L, Delaloge S, Martins I, Kroemer G., Free PMC Article | 09/14/2024 |
| Acyl coenzyme A binding protein (ACBP): An aging- and disease-relevant "autophagy checkpoint". | Acyl coenzyme A binding protein (ACBP): An aging- and disease-relevant "autophagy checkpoint".
Montégut L, Abdellatif M, Motiño O, Madeo F, Martins I, Quesada V, López-Otín C, Kroemer G., Free PMC Article | 09/15/2023 |
| Targeting fatty acid oxidation via Acyl-CoA binding protein hinders glioblastoma invasion. | Targeting fatty acid oxidation via Acyl-CoA binding protein hinders glioblastoma invasion.
Duman C, Di Marco B, Nevedomskaya E, Ulug B, Lesche R, Christian S, Alfonso J., Free PMC Article | 08/25/2023 |
| Acyl-CoA binding protein (ACBP) is highly expressed in the developing human kidney. | Acyl-CoA binding protein (ACBP) is highly expressed in the developing human kidney.
Piras M, Gerosa C, Fanni D, Cau F, Coni P, Murru R, Denotti G, Orrù G, Scano A, Ledda F, Van Eyken P, Coghe F, Faa G, Castagnola M. | 06/11/2022 |
| Serum DBI and biomarkers of neuroinflammation in Alzheimer's disease and delirium. | Serum DBI and biomarkers of neuroinflammation in Alzheimer's disease and delirium.
Conti E, Andreoni S, Tomaselli D, Storti B, Brovelli F, Acampora R, Da Re F, Appollonio I, Ferrarese C, Tremolizzo L., Free PMC Article | 07/3/2021 |
| Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity. | Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity.
Bravo-San Pedro JM, Sica V, Martins I, Pol J, Loos F, Maiuri MC, Durand S, Bossut N, Aprahamian F, Anagnostopoulos G, Niso-Santano M, Aranda F, Ramírez-Pardo I, Lallement J, Denom J, Boedec E, Gorwood P, Ramoz N, Clément K, Pelloux V, Rohia A, Pattou F, Raverdy V, Caiazzo R, Denis RGP, Boya P, Galluzzi L, Madeo F, Migrenne-Li S, Cruciani-Guglielmacci C, Tavernarakis N, López-Otín C, Magnan C, Kroemer G. | 09/5/2020 |
| By subgrouping individuals with ASD based on clinical phenotypes, and then performing an integrated transcriptome-proteome analysis, we identified DBI as a novel candidate protein for ASD with severe language impairment. | Phenotypic subgrouping and multi-omics analyses reveal reduced diazepam-binding inhibitor (DBI) protein levels in autism spectrum disorder with severe language impairment.
Pichitpunpong C, Thongkorn S, Kanlayaprasit S, Yuwattana W, Plaingam W, Sangsuthum S, Aizat WM, Baharum SN, Tencomnao T, Hu VW, Sarachana T., Free PMC Article | 12/14/2019 |
| was no significant difference in the rs2276596 genotype and allele frequencies of the DBI gene between these psychoses and healthy controls | No Relationships between Psychosis and the Diazepam Binding Inhibitor rs2276596 (C/A) Polymorphism in Japanese: An Exploratory Study.
Yoshiharia E, Narita S, Waga C, Numajiri M, Onozawa Y, Iwahashi K. | 04/6/2019 |
| ACBP increases the activity of ceramide synthase 2 (CerS2) by more than 2-fold and CerS3 activity by 7-fold. ACBP binds very-long-chain acyl-CoA esters, which is required for its ability to stimulate CerS activity. | Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein.
Ferreira NS, Engelsby H, Neess D, Kelly SL, Volpert G, Merrill AH, Futerman AH, Færgeman NJ., Free PMC Article | 06/10/2017 |
| Serum endozepine-4 levels are increased in hepatic coma. | Endozepine-4 levels are increased in hepatic coma.
Malaguarnera G, Vacante M, Drago F, Bertino G, Motta M, Giordano M, Malaguarnera M., Free PMC Article | 10/8/2016 |
| Structural and functional properties of ACBD1, commonly known as ACBP. [Review] | Long-chain acyl-CoA esters in metabolism and signaling: Role of acyl-CoA binding proteins.
Neess D, Bek S, Engelsby H, Gallego SF, Færgeman NJ. | 06/4/2016 |
| High ACBP expression is associated with non-small cell lung cancer. | Acyl-coenzyme A-binding protein regulates Beta-oxidation required for growth and survival of non-small cell lung cancer.
Harris FT, Rahman SM, Hassanein M, Qian J, Hoeksema MD, Chen H, Eisenberg R, Chaurand P, Caprioli RM, Shiota M, Massion PP., Free PMC Article | 02/14/2015 |
| results indicate that a dysfunction of the neurosteroid system might be operative in BPD in spite of unchanged DBI plasma levels. | Diazepam binding inhibitor and dehydroepiandrosterone sulphate plasma levels in borderline personality disorder adolescents.
Conti E, Nacinovich R, Bomba M, Uccellini O, Rossi MS, Casati M, Neri F, Ferrarese C, Tremolizzo L. | 01/24/2015 |
| There was a significant difference in the rs2276596 polymorphism C/A allele frequency of the DBI gene (P < 0.0001) between alcoholics and healthy controls. | Relationship between alcohol dependence and the DBI rs2276596 (C/A) polymorphism in Japanese.
Yoshihara E, Iwahashi K, Waga C, Murayama O, Ohtani N, Narita S, Nagahori K, Numajiri M, Onozawa Y. | 06/14/2014 |
| Acyl-CoA binding protein and epidermal barrier function. [review] | Acyl-CoA binding protein and epidermal barrier function.
Bloksgaard M, Neess D, Færgeman NJ, Mandrup S. | 04/19/2014 |
| Endogenous potentiation of GABAergic synaptic transmission and responses to GABA uncaging in the thalamic reticular nucleus is absent in mice in which DBI is deleted and mice in which benzodiazepine binding to alpha3 subunit-containing GABAARs is disrupted. | Endogenous positive allosteric modulation of GABA(A) receptors by diazepam binding inhibitor.
Christian CA, Herbert AG, Holt RL, Peng K, Sherwood KD, Pangratz-Fuehrer S, Rudolph U, Huguenard JR., Free PMC Article | 08/31/2013 |
| A human preadipocyte cell line SGBS is well suited to examine differential expression of the Acyl-CoA binding protein (ACBP) during adipogenesis. | Differential expression of alternative Acyl-CoA binding protein (ACBP) transcripts in an inducible human preadipocyte cell line.
Ludewig AH, Klapper M, Wabitsch M, Döring F, Nitz I. | 10/8/2011 |
| The regulation of novel low-abundance transcript variants of human acyl-CoA binding protein, was analysed. | Specific regulation of low-abundance transcript variants encoding human Acyl-CoA binding protein (ACBP) isoforms.
Nitz I, Kruse ML, Klapper M, Döring F., Free PMC Article | 08/27/2011 |
| Gene annotation enrichment analysis revealed ACBP-mediated down-regulation of 18 genes encoding key enzymes in glycerolipid, cholesterol and fatty acid metabolism. | ACBP knockdown leads to down-regulation of genes encoding rate-limiting enzymes in cholesterol and fatty acid metabolism.
Vock C, Biedasek K, Boomgaarden I, Heins A, Nitz I, Döring F. | 09/27/2010 |
| Data suggest that the presence of gamma-glutamyl hydrolase and diazepam-binding inhibitor in urine serves as a rationale for developing them as urinary markers of clinical outcomes for patients treated with neoadjuvant chemotherapy. | Genoproteomic mining of urothelial cancer suggests {gamma}-glutamyl hydrolase and diazepam-binding inhibitor as putative urinary markers of outcome after chemotherapy.
Pollard C, Nitz M, Baras A, Williams P, Moskaluk C, Theodorescu D., Free PMC Article | 01/21/2010 |
| ACBP is a transcriptional regulator of the HMGCS1 and HMGCR genes encoding rate-limiting enzymes of cholesterol synthesis pathway. | Transcriptional regulation of HMG-CoA synthase and HMG-CoA reductase genes by human ACBP.
Vock C, Döring F, Nitz I. | 01/21/2010 |
| study found a significant difference in the +529A/T (rs8192503) polymorphism allele frequency of the DBI gene between the alcoholics & controls; data suggest that mutation allele of the DBI gene polymorphism was one of the risk factors for alcoholism | The relationship between alcoholism and DBI gene polymorphism in Japanese--genotyping of the +529A/T in DBI gene polymorphism based on PCR.
Waga C, Ikeda K, Iwahashi K. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (5) articlesGenetical genomic determinants of alcohol consumption in rats and humans.
Tabakoff B, Saba L, Printz M, Flodman P, Hodgkinson C, Goldman D, Koob G, Richardson HN, Kechris K, Bell RL, Hübner N, Heinig M, Pravenec M, Mangion J, Legault L, Dongier M, Conigrave KM, Whitfield JB, Saunders J, Grant B, Hoffman PL, WHO/ISBRA Study on State and Trait Markers of Alcoholism. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.
Gratacòs M, Costas J, de Cid R, Bayés M, González JR, Baca-García E, de Diego Y, Fernández-Aranda F, Fernández-Piqueras J, Guitart M, Martín-Santos R, Martorell L, Menchón JM, Roca M, Sáiz-Ruiz J, Sanjuán J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A, Psychiatric Genetics Network Group. Candidate gene association study of type 2 diabetes in a nested case-control study of the EPIC-Potsdam cohort - role of fat assimilation.
Fisher E, Nitz I, Lindner I, Rubin D, Boeing H, Möhlig M, Hampe J, Schreiber S, Schrezenmeir J, Döring F. Association of acyl-CoA-binding protein (ACBP) single nucleotide polymorphisms and type 2 diabetes in two German study populations.
Fisher E, Nitz I, Gieger C, Grallert H, Gohlke H, Lindner I, Dahm S, Boeing H, Burwinkel B, Rathmann W, Wichmann HE, Schrezenmeir J, Illig T, Döring F. Association of a Met88Val diazepam binding inhibitor (DBI) gene polymorphism and anxiety disorders with panic attacks.
Thoeringer CK, Binder EB, Salyakina D, Erhardt A, Ising M, Unschuld PG, Kern N, Lucae S, Brueckl TM, Mueller MB, Fuchs B, Puetz B, Lieb R, Uhr M, Holsboer F, Mueller-Myhsok B, Keck ME. | 03/13/2008 |
| PPRE in intron 1 of the ACBP gene is a bona fide PPARgamma-response element. | The gene encoding the Acyl-CoA-binding protein is activated by peroxisome proliferator-activated receptor gamma through an intronic response element functionally conserved between humans and rodents.
Helledie T, Grøntved L, Jensen SS, Kiilerich P, Rietveld L, Albrektsen T, Boysen MS, Nøhr J, Larsen LK, Fleckner J, Stunnenberg HG, Kristiansen K, Mandrup S. | 01/21/2010 |
| Data show for the first time in a physiological context that transgenic expression of acyl-coenzyme A binding protein may play a role in liver fatty acyl-coenzyme A metabolism. | Acyl-coenzyme A binding protein expression alters liver fatty acyl-coenzyme A metabolism.
Huang H, Atshaves BP, Frolov A, Kier AB, Schroeder F. | 01/21/2010 |