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    FSIP1 fibrous sheath interacting protein 1 [ Homo sapiens (human) ]

    Gene ID: 161835, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    FSIP1 enhances the therapeutic sensitivity to CDK4/6 inhibitors in triple-negative breast cancer patients by activating the Nanog pathway.

    FSIP1 enhances the therapeutic sensitivity to CDK4/6 inhibitors in triple-negative breast cancer patients by activating the Nanog pathway.
    Chen G, Sun L, Gu X, Ai L, Yang J, Zhang Z, Hou P, Wang Y, Ou X, Jiang X, Qiao X, Ma Q, Niu N, Xue J, Zhang H, Yang Y, Liu C.

    12/20/2023
    FSIP1 Is Associated with Poor Prognosis and Can Be Used to Construct a Prognostic Model in Gastric Cancer.

    FSIP1 Is Associated with Poor Prognosis and Can Be Used to Construct a Prognostic Model in Gastric Cancer.
    Yan X, Dai J, Han Y, You Q, Liu Y., Free PMC Article

    06/18/2022
    Loss-of-function variants in FSIP1 identified by targeted sequencing are associated with one particular subtype of mucosal melanoma.

    Loss-of-function variants in FSIP1 identified by targeted sequencing are associated with one particular subtype of mucosal melanoma.
    Chen M, Wu Y, Li W, Zhang X, Chen L, Zheng X, Zuo X, Zhou F, Hong Y, Cheng H, Zhang M, Chen Z, Wu Q, Zhang X, Zhang B.

    09/12/2020
    FSIP1 bound to the multidrug resistance protein 1 (MRP1) and stabilized it, and knocking out FSIP1 decreased MRP1 expression and increased cellular docetaxel accumulation. In sum, FSIP1 promotes breast carcinogenesis and mediates docetaxel resistance.

    Over-expression of FSIP1 promotes breast cancer progression and confers resistance to docetaxel via MRP1 stabilization.
    Yan M, Wang J, Ren Y, Li L, He W, Zhang Y, Liu T, Li Z., Free PMC Article

    06/6/2020
    FSIP1 overexpression correlated with decreased overall survival in hormone receptor-positive breast cancer patients.

    FSIP1 is correlated with estrogen receptor status and poor prognosis.
    Li X, Song X, Ma J, Zhao Y, Jiang Q, Zhao Z, Li M.

    04/18/2020
    High FSIP1 expression is associated with drug resistance in triple-negative breast cancer.

    FSIP1 regulates autophagy in breast cancer.
    Liu C, Sun L, Yang J, Liu T, Yang Y, Kim SM, Ou X, Wang Y, Sun L, Zaidi M, New MI, Yuen T, Guo Q., Free PMC Article

    02/23/2019
    FSIP1 binds HER2 directly, which regulates breast cancer growth and invasiveness

    FSIP1 binds HER2 directly to regulate breast cancer growth and invasiveness.
    Liu T, Zhang H, Sun L, Zhao D, Liu P, Yan M, Zaidi N, Izadmehr S, Gupta A, Abu-Amer W, Luo M, Yang J, Ou X, Wang Y, Bai X, Wang Y, New MI, Zaidi M, Yuen T, Liu C., Free PMC Article

    06/9/2018
    Results suggest that evaluating fibrous sheath interacting protein 1 (FSIP1) status in addition to TNM stage during routine pathological examinations could improve prognostic predictions in non-small cell lung cancer (NSCLC) patients.

    Elevated fibrous sheath interacting protein 1 levels are associated with poor prognosis in non-small cell lung cancer patients.
    Mao Y, Xu R, Liu X, Shi W, Han Y., Free PMC Article

    08/12/2017
    FSIP1 may play an important role in the tumorigenesis and invasion of breast cancer and is a potential biomarker for breast cancer diagnosis or prognosis.

    Expression and clinicopathological significance of FSIP1 in breast cancer.
    Zhang H, Luo M, Jin Z, Wang D, Sun M, Zhao X, Zhao Z, Lei H, Li M, Liu C., Free PMC Article

    03/19/2016
    prevalence and uniformity of FSIP1 expression in breast tumors

    Elevated expression of cancer/testis antigen FSIP1 in ER-positive breast tumors.
    Chapman KB, Prendes MJ, Kidd JL, Sternberg H, West MD, Wagner J.

    03/22/2014
    association between the variants in FSIP1 and aspirin intolerant asthma occurrence among asthmatics in a Korean population

    Positive association between aspirin-intolerant asthma and genetic polymorphisms of FSIP1: a case-case study.
    Kim JY, Kim JH, Park TJ, Bae JS, Lee JS, Pasaje CF, Park BL, Cheong HS, Park JS, Park SW, Uh ST, Kim MK, Choi IS, Cho SH, Choi BW, Park CS, Shin HD, Kim JY, Kim JH, Park TJ, Bae JS, Lee JS, Pasaje CF, Park BL, Cheong HS, Park JS, Park SW, Uh ST, Kim MK, Choi IS, Cho SH, Choi BW, Park CS, Shin HD., Free PMC Articles: PMC2896935, PMC2896935

    10/23/2010
    Observational study of gene-disease association. (HuGE Navigator)

    Positive association between aspirin-intolerant asthma and genetic polymorphisms of FSIP1: a case-case study.
    Kim JY, Kim JH, Park TJ, Bae JS, Lee JS, Pasaje CF, Park BL, Cheong HS, Park JS, Park SW, Uh ST, Kim MK, Choi IS, Cho SH, Choi BW, Park CS, Shin HD, Kim JY, Kim JH, Park TJ, Bae JS, Lee JS, Pasaje CF, Park BL, Cheong HS, Park JS, Park SW, Uh ST, Kim MK, Choi IS, Cho SH, Choi BW, Park CS, Shin HD., Free PMC Articles: PMC2896935, PMC2896935

    06/30/2010
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
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