| A novel cancer-germline gene DAZL promotes progression and cisplatin resistance of non-small cell lung cancer by upregulating JAK2 and MCM8. | A novel cancer-germline gene DAZL promotes progression and cisplatin resistance of non-small cell lung cancer by upregulating JAK2 and MCM8.
Zhou L, Le MNU, Du Y, Chen X, Jin M, Xiang H, Xia LE, Zhou J, He J, Ning Y. | 05/31/2024 |
| Association of DAZL polymorphisms and DAZ deletion with male infertility: a systematic review and meta-analysis. | Association of DAZL polymorphisms and DAZ deletion with male infertility: a systematic review and meta-analysis.
Nongthombam PD, Malini SS. | 05/24/2023 |
| DAZL regulates proliferation of human primordial germ cells by direct binding to precursor miRNAs and enhances DICER processing activity. | DAZL regulates proliferation of human primordial germ cells by direct binding to precursor miRNAs and enhances DICER processing activity.
Yan A, Xiong J, Zhu J, Li X, Xu S, Feng X, Ke X, Wang Z, Chen Y, Wang HW, Zhang MQ, Kee K., Free PMC Article | 11/12/2022 |
| Direct reprogramming of human Sertoli cells into male germline stem cells with the self-renewal and differentiation potentials via overexpressing DAZL/DAZ2/BOULE genes. | Direct reprogramming of human Sertoli cells into male germline stem cells with the self-renewal and differentiation potentials via overexpressing DAZL/DAZ2/BOULE genes.
Zhang W, Chen W, Cui Y, Wen L, Yuan Q, Zhou F, Qiu Q, Sun M, Li Z, He Z., Free PMC Article | 03/19/2022 |
| The marker of alkyl DNA base damage, N7-methylguanine, is associated with semen quality in men. | The marker of alkyl DNA base damage, N7-methylguanine, is associated with semen quality in men.
Altakroni B, Nevin C, Carroll M, Murgatroyd C, Horne G, Brison DR, Povey AC., Free PMC Article | 11/22/2021 |
| Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells. | Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells.
Zhang F, Liu R, Zhang H, Liu C, Liu C, Lu Y., Free PMC Article | 02/13/2021 |
| computational analysis of free energy change due to this point mutation using GROMOS96 indicated decreased stability of the DAZL protein. The N109T variant in an infertile male population may provide a genetic marker for mutational analysis of DAZL | In silico analysis of non-synonymous single nucleotide polymorphisms in human DAZL gene associated with male infertility.
Nailwal M, Chauhan JB. | 03/31/2018 |
| Data suggest that DAZL may be one such factor in human female fertility | Is there a role for DAZL in human female fertility?
Rosario R, Adams IR, Anderson RA., Free PMC Article | 01/27/2018 |
| Through the translational regulation of novel RNA targets SMC1B and TEX11, DAZL may have a key role in regulating chromosome cohesion and DNA recombination; two processes fundamental in determining oocyte quality and whose establishment in foetal life may support lifelong fertility. | RNA immunoprecipitation identifies novel targets of DAZL in human foetal ovary.
Rosario R, Smith RW, Adams IR, Anderson RA., Free PMC Article | 12/23/2017 |
| hypermethylation of DAZL and BOULE promoters in human sperm is associated with human infertility | Highly conserved epigenetic regulation of BOULE and DAZL is associated with human fertility.
Zhang C, Xue P, Gao L, Chen X, Lin K, Yang X, Dai Y, Xu EY. | 09/9/2017 |
| data can be used to further elucidate the role of NANOS3 and DAZL in germ cell development both in vitro and in vivo | Over Expression of NANOS3 and DAZL in Human Embryonic Stem Cells.
Panula S, Reda A, Stukenborg JB, Ramathal C, Sukhwani M, Albalushi H, Edsgärd D, Nakamura M, Söder O, Orwig KE, Yamanaka S, Reijo Pera RA, Hovatta O., Free PMC Article | 06/24/2017 |
| DAZL was not expressed either in normal cultures or lesions from cervixes with papillomavirus infections and cervical intraepithelial neoplasia. | OCT-4 and DAZL expression in precancerous lesions of the human uterine cervix.
Stefanidis K, Pergialiotis V, Christakis D, Patta J, Stefanidi D, Loutradis D. | 12/17/2016 |
| analysis demonstrated that SNP260 of DAZL did not contribute to oligo/azoospermia while SNP386 was correlated to male infertility | Association of polymorphisms of A260G and A386G in DAZL gene with male infertility: a meta-analysis and systemic review.
Chen P, Wang X, Xu C, Xiao H, Zhang WH, Wang XH, Zhang XH., Free PMC Article | 10/1/2016 |
| Neither the A260G nor the A386G polymorphism of DAZL appeared to be involved in male infertility. | Analysis of DAZL SNP260 and SNP386 in infertile Chinese males using multi-analyte suspension array.
Zhu Y, Ma M, Wan L, Zhang D, Zhao L, Wei L, Li L. | 06/20/2015 |
| analysis of T12A and T54A polymorphisms role in the development of male infertility (Meta-Analysis) | Association between DAZL polymorphisms and susceptibility to male infertility: systematic review with meta-analysis and trial sequential analysis.
Zhang S, Tang Q, Wu W, Yuan B, Lu C, Xia Y, Ding H, Hu L, Chen D, Sha J, Wang X., Free PMC Article | 12/20/2014 |
| demonstrate that Boll is also transiently expressed during oogenesis in the fetal mouse ovary, but is simultaneously co-expressed within the same germ cells as Dazl | A developmental stage-specific switch from DAZL to BOLL occurs during fetal oogenesis in humans, but not mice.
He J, Stewart K, Kinnell HL, Anderson RA, Childs AJ., Free PMC Article | 07/19/2014 |
| Abnormal DNA methylation of the DAZL promoter might represent an epigenetic marker of male infertility. | Altered DNA methylation patterns of the H19 differentially methylated region and the DAZL gene promoter are associated with defective human sperm.
Li B, Li JB, Xiao XF, Ma YF, Wang J, Liang XX, Zhao HX, Jiang F, Yao YQ, Wang XH., Free PMC Article | 05/24/2014 |
| Amniotic fluid-derived stem cells (AFSc) seem to express Nodal, Nanog and DAZL and it speculated that the regulation of self-renewal in AFSc could be similar as in human embryonic stem cells. | Nodal, Nanog, DAZL and SMAD gene expression in human amniotic fluid stem cells.
Stefanidis K, Pergialiotis V, Christakis D, Loutradis D, Antsaklis A. | 03/8/2014 |
| The A260G and A386G polymorphisms of the DAZL gene are not correlated with astheno-teratozoospermia-induced male infertility in the Han Chinese population. | [DAZL gene polymorphisms and astheno-teratozoospermia].
Ye LW, Yu QF, Yang XX, Li JP, Wu XQ, Zhang YH, Mao XM. | 09/28/2013 |
| study identified the core promoter of the DAZL gene; also provided preliminary evidence for the role of a novel SNP of the DAZL gene promoter in spermatogenic failure | A single-nucleotide polymorphism of the DAZL gene promoter confers susceptibility to spermatogenic failure in the Taiwanese Han.
Teng YN, Chang YP, Tseng JT, Kuo PH, Lee IW, Lee MS, Kuo PL. | 01/12/2013 |
| overexpression of VASA and or DAZL, in both embryonic and induced pluripotent stem cells promoted differentiation into primordial germ cells, and maturation and progression through meiosis was enhanced. | Divergent RNA-binding proteins, DAZL and VASA, induce meiotic progression in human germ cells derived in vitro.
Medrano JV, Ramathal C, Nguyen HN, Simon C, Reijo Pera RA., Free PMC Article | 06/16/2012 |
| results showed no significant differences in the frequency of DAZL AG (P = 0.58) and MTHFR CT (P = 0.44) between oligozoospermic infertile men and controls | DAZL 260A > G and MTHFR 677C > T variants in sperm DNA of infertile Indian men.
Kumar K, Venkatesh S, Sharma PR, Tiwari PK, Dada R. | 03/3/2012 |
| These results suggest that incorrect epigenetic marks in germline gene DAZL may be correlated with male gametogenic defects. | Incorrect DNA methylation of the DAZL promoter CpG island associates with defective human sperm.
Navarro-Costa P, Nogueira P, Carvalho M, Leal F, Cordeiro I, Calhaz-Jorge C, Gonçalves J, Plancha CE., Free PMC Article | 01/15/2011 |
| 386A-->G was significantly correlated with sperm count (P<0.0001) and motility (P<0.005) and 584+28c-->t was marginally correlated with sperm morphology. | Quantitative trait analysis suggests human DAZL may be involved in regulating sperm counts and motility.
Hsu CC, Kuo PH, Lee IW, Su MT, Tseng JT, Kuo PL. | 01/1/2011 |
| expression of spermatogenic phenotypes of partial AZFc deletions is independent of the variations in DAZL and BOULE in the Han population | Phenotypic expression of partial AZFc deletions is independent of the variations in DAZL and BOULE in a Han population.
Chen P, Ma M, Li L, Zhang S, Su D, Ma Y, Liu Y, Tao D, Lin L, Yang Y. | 06/28/2010 |